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영재 학생들을 위한 과학사-CPS 수업 모형을 활용한 분자생물 영역 수업 프로그램의 개발 및 적용
이주현 ( Ju Hyun Lee ),이미숙 ( Mi Sook Lee ),주희영 ( Hee Young Ju ),이길재 ( Kil Jae Lee3 ) 경북대학교 과학교육연구소 2011 科學敎育硏究誌 Vol.35 No.2
This research was aimed to develop and apply the molecular genetics teaching program based on the history of science and creative problem solving model (HS-CPS model) for gifted students. Based on the strategies of creative problem solving and scientific theory development, the HS-CPS teaching program were developed. This program was applied to 8 first and second graders of the special class for invention activity in a high school. Creative problem solving ability in science and the understanding of DNA and gene concept were tested in pre and post of 12 lessons. The results were as follows: First, creative problem solving ability in science was improved meaningfully. Second, HS-CPS teaching program was effective in the understanding of DNA and gene concepts. Third, the students responded positively to the program evaluation questionnaire.
Alkylhalide가 Mouse의 LDH isozyme 분포에 미치는 영향 : Cellulose Acetate Electrophoresis Method
권미경,김영옥,박은주,이동화,이명미,이문희,이양자 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-
The effect of Carbontetrachloride administration on Lactatedehydrogenase isozyme patterns were analyzed by cellulose acetate electrophoresis for the brain, heart, kidney, lung, liver and mouse muscle. Each other tissue was found to have a characteristic distribution of these isozymes. At normal condition, aerobic tissue such as brain, heart, kidney, and lung were found to have all five isozymes from LDH_1 to LDH_5, while anaerobic tissues such as liver and muscle were found to have superiorly LDH_5 The toxicity of Carbontetrachloride administration was most prominence in the liver, and lung toxicity was occured also.
Trans-sphenoidal approach에 의한 pituitary microadenoma 수술 후의 임신 1례
여준규,이두룡,이미정,최종무,이원주,류효충,임만빈,최은주 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3
We treated a patient with pituitary microadenoma having hyperprolactinemia and irregular menstruation infertility by transsphenoidal microsurgery. Her menstrual cycle become irregular after marriage but previous menstrual cycle was regular. When she visited our hospital due to infertility, initial serum prolactine level was slightly elevated 35.68ng/ml, During bromecriptine therapy, abrupt increase of serum prolactine level up to 126.52 ng/ml and headache and facial flush and galactorrhea developed. Pituitary microadenoma was confirmed by CT and MRI. The patient underwent transsphenoidal microsurgery. Patient was pregnant after surgery, and it was confirmed by USG and she is following up, OPD now.
일 도농복합지역 저소득층 노인의 건강문제 분석 : 보건소 방문간호사업 대상자 중심으로
고일선,,이태화,이경자,이정렬,임미혜,천의영,주윤미,이계철 노인간호학회 2005 노인간호학회지 Vol.7 No.2
Purpose: The purpose of this study was to analyze the health problems of low-income aged with chronic illness living in urban-rural composite area. Method: The sample consisted of 440 aged who were receiving home care services from a public health center. MDS-HC was applied to analyze the health problems of the aged. Data were collected through a face- to-face interview by six trained interviewers from June 28 to July 15, 2004. Result: Subjects had average number of 8 health problems in both urban and rural area. Lack of preventive health care measure, pain, and visual function were the most frequent health problem. The rural aged had more pain, bowel management problems, compared to the urban aged having more urinary incontinence and indwelling catheter. There were many health problems related to falls and pressure ulcers with middle-old aged in urban, and old-old aged in rural area. Conclusion: The results of this study showed strategies for care intervention of low-income elderly to put in practice. Therefore, tailored-service for each subject should be provided.
흑두로 제조한 청국에서 분리된 Bacillus subtillus BB-1으로부터 혈전용해효소 유전자 크로닝 및 특성규명
이영훈,이성호,전주미,김홍출,조용운,박기훈,최영주,갈상완 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.
A bacterium producing five fibrinolytic isozymes was isolated from black bean chung kuk. The bacterium was identified as Bacillus subtilis BB-1 by 16s rDNA sequence homology search. A gene out of five fibrinolytic genes in the Bacillus subtilis BB-1 was cloned by shot-gun method. A Cla ⅠDNA fragment of B. subtilis BB-1 chromosome was cloned in to pBluescript ⅡSK(-) and showed the fibrinolytic activity to bacterial cells. The Cla ⅠDNA fragment was sequenced and the sequences did not show homology with gene for protease or fibrinolytic enzyme genes in other organisms. The Cla ⅠDNA fragment was reduced to 2,142 bp by activity-guided PCR cloning method. The optimum pH and temperature of the enzyme were 5.0 and 35℃, respectively. Substrate specificity of the fibrinolytic enzyme was detected in skim milk, casein, gelatin and blood agar plates. The activity of the enzyme was not detected with these substrates. Taken together, this enzyme is a new fibrinolytic enzyme and may be used to prevent thrombosis and arteriosclerosis.
이경민,송주희,장재혁,심수정,강양화,안재경,이숭호,박미영,정문호 대한보건협회 2002 대한보건연구 Vol.28 No.4
Object The usage of agricultural chemical is on the increasing. Use of pesticides has increased agricultural production. However, negative externalities from such use have increased too. Pesticide poisoning is a major public problem. The purpose if this study is to find out the relationship between keeping the safety rules or protective equipments or attending safety education or dose of pesticides use , and poisoning experience. Methods For Gu, H.M. and Pack, S.G. study , we obtained questionnaire data concerning pesticides poisoming. A person interviews on 203 were conducted in two villages in Sinmeari and woulbonri Chunchun , Kangwon province, July 2002. Result 1. 144 people(70.9%) have sprayed pesticides and the rata of experiences of pesticide poisoning was 26% among 144. Spraying time of pesticides was 1-2 hours in 63.9% of farmers. Rate of using the protective equipment was 25.7% (protective clothes), 49.3% (Mask), 48.6 (Gloves), 7.0 (Protective glasses), 64.6% (boots) respectively. 2. Chi-square and multiple logistic regression analysis showed that Duration of spraying per day (<2hr) and using of mask(protective equipment)are significantly association with poisoning experience.(x^2=5.2684 p=0.0217, CI=0.140-0.5853 OR=0.346 p=0.0211 respectively). But no association between poisoning experience and keeping safety rule, attending of safety education. 3. Spraying pesticides. Duration of spraying pesticides, reading manuals and no spraying at fatigue (keeping safety rule) are significantly association with symptom experience(x^2=14.0621 p=0.0002, x^2=7.0639 p=0.0079, CI01.395-10.950 OR=3.908 p=0.0095, CI=0.101-0.726 OR=0.271 0.0094 respectively). But no association between symptom experience and protective equipments, attending of safety education.
이온화가스와 응집공정을 조합한 축산폐수의 처리시 용존 유기물의 특성에 관한 연구
이은주,정팔진,김민정,현미희 한국물환경학회 2004 한국물환경학회지 Vol.20 No.6
This study was performed to investigate the variations of hydrophilic and hydrophobic organic matter fractions in soluble organic matter according to livestock wastewater treatment by ionized gas and coagulation effect to these fractions after ionized gas contact. As a result of experiment, because of ionized gas contact, particle in the surface of livestock wastewater was more smaller and the result was consisted of particle size analysis and the amount of small size was increased. Also, we confirmed that organic matters in livestock wastewater by ionized gas contact were removed. The relation equation between ionized gas contact time(X) and TCOD_(cr)(Y) was shown as yscale(y)=3.748-0.431^*xscale(X). That between ionized gas contact time(X) and SCOD_(cr)(Y) was yscale(y)=3.283-0.463^* xscale(X). As respects the HPL(hydrophilic matter)and HPO(hydrophobic matter) fractions of raw in livestock wastewater treatment plant, HPL fraction was 53.2% and HPO fraction was 46.8%. But, HPO fraction according to ionized gas treatment was increased at 30min and after that time, HPL fraction was increased. Also, when we performed coagulation process after ionized gas treatment of raw wastewater, the removal efficiency of organic matter was the highest at 30min of ionized gas treatment because of the variation of HPL and HPO fractions in organic matter by ionized gas. In coagulation process following after ionized gas process, HPO was removed more effective than HPL.
박미선,박호원,서현우,이주현 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4
선양 치성 종양(adenomatoid odontogenic tumor)은 악골에 드물게 발생하는 치성 기원의 종양이다. 이전에는 법랑모세 포종(ameloblastoma)의 한 종류로 여겨졌으나 양성이며 재발되는 경우는 극히 드물다. 상악 견치에 호발하며 대개는 무증 상이지만 크기가 천천히 커져 무통성 종창을 일으킬 수 있다. 방사선학적으로 함치성 낭종(dentigerous cyst) 및 단방성 법 랑모세포종(unicystic ameloblastoma)과 매우 유사하다. 일반적으로 보존적인 소파술(curettage) 및 적출술(enucleation) 을 통해 치료한다. 본 증례는 하악 우측 측절치 미맹출을 주소로 내원한 10세 여자 환아에서 방사선 사진 검사를 통해 치아의 매복 및 병소를 확인하고 적출술을 시행하였다. 치아에는 브라켓을 부착하여 교정적 정출을 유도하였다. 조직학적 검사를 통해 선양 치성 종 양으로 확진되었으며 양호한 치료 결과를 보였기에 보고하는 바이다. Adenomatoid odontogenic tumor(AOT) is an infrequent odontogenic tumor which arise in the jaw. It was considered as a variant of ameloblastoma. The adenomatoid odontogenic tumor is clearly benign and, in contrast to the ameloblastoma, present a very low recurrence. It most often appears in the canine region of the maxilla. The adenomatoid odontogenic tumor is frequently asymptomatic, however it may cause painless swelling. The radiological findings of adenomatoid odontogenic tumor frequently share characteristics of dentigerous cyst and unicystic ameloblastoma. Conservative surgical enucleation and curettage are the treatment of choice. In this case a 10-year-old child was presented with mandibular right lateral incisor in unerupted. Radiographically, the tooth was impacted and a radiolucency was seen in the area. The lesion was enuclated without extraction of the tooth. Bracket was attached on the tooth for orthodontic extrusion installed. Histopathologically adenomatoid odontogenic tumor was revealed.