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      • KCI등재

        수영운동과 DA-9601투여가 흰쥐의 소화기계에서 IL-8, TNF-a와 COX-2유전자 발현에 미치는 영향

        최은주,차광석 한국운동생리학회(구 한국운동과학회) 2012 운동과학 Vol.21 No.3

        최은주, 차광석. 수영운동과 DA-9601투여가 흰쥐의 소화기계에서 IL-8, TNF-a와 COX-2유전자 발현에 미치는 영향. 운동과학, 제21권 제3호. 339-346, 2012. 본 연구는 수영운동과 DA-9601의 투여가 소화기관내 염증성 사이토카인과 케모카인 발현에 어떠한 영향을 미치는지 규명하고자 하였다. 이 연구를 위하여 20마리의 BALB/c마우스를 대상으로 각각 5마리씩 4그룹 통제그룹(CON), DA섭취그룹(DA), 운동그룹(EX), DA-9601투여와 운동병행그룹(DA+EX)으로 분류하였다. DA-9601은 수영운동 30분 전에 경구 투여 50 mg/g/day로 실시하였으며, 조직은 마지막 운동 훈련 직후 소화기관인 소장과 대장에서 적출하였다. 그 결과 염증성 사이토카인인 IL-8, TNF-a, COX-2유전자가 운동그룹(EX)에서 증가하였으며, DA-9601투여와 운동병행그룹(DA+EX)에서 유의하게 감소하는 것을 볼 수 있었다. 이상과 같은 연구 결과를 종합해 볼 때 수영운동은 소화기계에 염증성 사이토카인 유전자를 증가시켜 염증상태의 환경을 제시하였다. 따라서 DA-9601의 투여가 운동으로 인한 소화기계의 염증성 케모카인 및 사이토카인을 완화시키는 것을 증명하였다. Choi, E. J., Cha, K. S. The effects of the IL-8, TNF-a and COX-2 gene expression on DA-9601 administration and swimming exercise in small intestine and colon, Exercise Science, 21(3): 339-346, 2012, The purpose of this study is to identify how DA-9601 administration and swimming exercise effect to Inflammatory Cytokines and Chemokine in digestive system. To perform this experiment, we prepared 20 BALB/c mice and divided into 4 groups (5 rats in each group). These 4 groups were designated as followings:control group(con), DA administration group(DA), exercise group(EX) and exercise group with DA-9601 administration(EX+DA). DA-9601 was steadily administered(50 mg/g/day) during 30 minutes before swimming exercise, and the organization was removed from small intestine and colon after the last exercise training. From above process, we identified that inflammatory cytokines IL-8, TNF-a, COX-2 genes were steadily increased in exercise group (EX), and they were significantly decreased in an exercise group which was DA-9601 ingested (DA+EX). As a result of this experiment, we inferred that high-intensity exercise such as a swimming exercise can cause an inflammatory condition of the environment by increasing inflammation-related genes in digestive system. Therefore, DA-9601 administration which has antioxidant and anti-inflammatory effect would be necessary to repress inflammatory cytokines due to exercise. Also, ingestion with antioxidant products is ideally considered and recommended in order to repress the Inflammation in intestines.

      • 교사추천서와 자기소개서 분석을 통한관찰∙추천제의 영재 판별 효과성 탐색

        최은주,유미현 한국과학영재교육학회 2013 과학영재교육 Vol.5 No.1

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        The purpose of this study was to investigate the effectiveness of observation- recommendation system analyzing teacher recommendation letter and self-introduction essay and compare with the educational results. For this purpose, the frequency and characteristics shown in gifted teacher recommendation letter was analyzed. As a result, it showed that teacher recommendation evaluate more objectively than students’self-introduction essay. However, behavioral characteristics of the 32 최은주∙유미현gifted was more frequently mentioned in students’self-introduction essay. Teacher recommendations also put importance on social and creative characteristics of gifted students, and self-introduction essay emphasizes affective and creative characteristics of gifted students. Secondly, investigating the correlation between the observed results in the actual educational situation and the characteristics shown in teacher recommendations and self-introduction essay. As a result, there were some significant correlations among teacher recommendation letter, self introduction essay and the observed results. However, rank at the time of admission did not show a significant correlation with the rank after educating in Gifted Education Center. It depends on the efforts of students and admission rank could be different with results of education. 본 연구의 목적은 새로운 과학영재 판별 방법인 관찰∙추천제에 사용되는 추천서, 자기소개서를 분석하고영재학생들의 실제 교육상황에서 결과와 비교하여 관찰∙추천제의 효과성을 조사하는 것이다. 이를 위해 첫 번째로 교사추천서에 나타난 영재 행동 특성의 빈도 및 비율을 분석하였다. 분석 결과 교사추천서가 학생들을 보다 객관적으로 평가하고 있는 것으로 나타났다. 그러나 자기소개서에서 영재 행동 특성에 대한 언급 빈도가 높았다. 또한 교사추천서는 영재 학생의 사회적 특성과 창의적 특성을 중요시하였고, 자기소개서는 정의적과 창의적 특성을중요시하는 것으로 나타났다. 두 번째로 교사추천서와 자기소개서의 특성, 그리고 실제 교육상황에서 관찰결과와의 상관관계를 조사하였다. 그 결과 교사추천서, 자기소개서 및 영재교육원 교육장면 관찰 일부 영역에서 유의미한 상관관계가 나타났다. 그러나 입학 당시의 석차는 영재교육원에서의 교육 후 석차와는 유의미한 상관관계가나타나지 않았다. 이는 영재교육원의 교육결과는 입학석차와는 다르며, 학생의 노력 여하에 따라 달라지는 것을의미한다.

      • KCI등재

        조선풍속사진, 가족표상과 여성

        崔恩珠 일본어문학회 2013 일본어문학 Vol.63 No.-

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        帝国主義発現の視覚メディアであった朝鮮風俗写真において、女性は帝国男性の性的欲望を満たすことで朝鮮の未開と野蛮性を表し、植民支配を正当化させたと指摘されている。本稿では、朝鮮風俗写真における女性表象を、当時朝鮮において公的談論の対象となった'家族'との関わりの中で分析することで、女性表象がもつ植民統治との関連性を明らかにし、朝鮮風俗写真の意義を指摘することを目的とする。 '家族'と対比され、近代ㆍ文明と意識された家族の表象には'家庭'という命名がついている。この'家庭'表象は、まず、日本式戸籍制度のもつ女性抑圧的な側面を不可視化し、植民家族政策の実行において有効性を持ったといえよう。二番目に、母性を女性の本能と位置づける'親子'表象が、'家庭'と'子供の再発見'と遭遇することで、植民女性の役割が'母'に固定されたのである。朝鮮風俗写真の家族と関わる女性表象には、植民支配の正当化のみならず、植民統治と直接関わる概念が見られるのである。

      • 대학도서관의 온라인 참고서가 구축현황과 온라인 참고정보원의 유형분석에 관한 연구

        최은주,Choi, Eun-Ju 한국과학기술정보연구원 과학기술정보센터 2007 정보관리연구 Vol.38 No.1

        본 연구는 국내 대학도서관의 온라인 참고서가 구축현황과 참고서가 접근을 위한 접근점 및 온라인 참고정보원의 유형을 분석해 보고자 하였다.서울.경기지역 소재41개 대학도서관을 조사대상으로 홈페이지의 직접 접속을 통해 자료를 수집하였다. 41개 관 중 30개 관에 참고서가가 구축되어 있었으며, 참고정보원에 접근하기 위한 홈페이지상의 메뉴로는 "이용자서비스", "전자정보원", "참고정보원"의 순이었다. 제공되고 있는 참고정보원의 유형은 도서관별로 다양하였으며, "명부/명감", "사전", "통계", "백과사전"의 순으로 밝혀졌다. 국내 대학도서관의 온라인 참고서가 구축 및 활성화를 위하여 선정을 위한 평가기준의 설정 및 적용, 접근의 용이성, 주제별 접근방법, 참고정보원의 계속적인 갱신 및 추가 등을 제언하였다. This study aimed to investigate present status of online reference shelf and analyze access point in the home page and types of online reference sources in the university library. Data were collected by accessing home pages of 41 university libraries in the region of Seoul and Kyonggi-Do. 30 libraries had prepared reference shelf out of 41 libraries, and "User Service", "Electronic Reference Sources", or "Reference & Information Sources" were mostly used as home page menu. Types of references sources varied among libraries, and "Directories", "Dictionaries", "Statistics" or "Encyclopedias" were mostly loaded types in the reference shelf. For the enhancement of reference services through reference shelf, establishing and applying standards for evaluation, ease of access, access by subject, and continuous updates and additions of reference sources were suggested.

      • KCI등재

        동북아시아 지역 전통복식 디자인을 응용한 셔츠디자인 개발-글로벌 패션문화상품-

        최은주 한국의류산업학회 2020 한국의류산업학회지 Vol.22 No.4

        In order to develop high value fashion culture products capable of reaching the global market, this study developed the original traditional clothing design of Northeast Asian countries according to a global perspective. This study applied the structural formality of traditional clothing to fashion cultural products. This study developed designs using Deel of Mongolia, Makap of China Korean Dang-ui / Dan-ryung, and Haori of Japan. The research methods are theoretically examined using literature on traditional clothing in Northeast Asia. First, it designed a shirt design using Adobe Illustrator CS6 and created a pattern with the Yuka program as well as applied CLO 5.0 (a 3D virtual dressing system from CLO Virtual Fashion Co.). A survey was also conducted on individual interest for the developed fashion cultural products. The design method obtained various design effects by applying the method of adding point detail parts of the clothes to the shirt that represented each country among their traditional clothes. This research can be used as basic data for the global fashion cultural products market that can contribute to maintaining the originality of each country in the global era, expanding tourism income to succeed and develop culture and tradition.

      • KCI등재

        Four Flavonoids from Echinosophora koreensis and their Effects on Alcohol Metabolizing Enzymes

        최은주,권학철,Young Chang Sohn,Chun Woo Nam,Hyun Bong Park,Cheol Young Kim,양현옥 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.6

        A new prenylated dihydroflavonol, 3-hydroxy-kenusanone B 1, as well as three other known isoflavanones, sophoronol 2, sophoraisoflavanone A 3 and kenusanone H 4, were isolated from the rhizomes of Echinosophora koreensis. The structures of these compounds were elucidated using spectroscopic analyses that included extensive 2D NMR, optical rotation spectrometry and mass spectrometry. All four flavonoids enhanced the activities of alcohol metabolizing enzymes such as alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) at micromolar concentrations. Sophoronol 2 showed a nine-fold increased activation of alcohol dehydrogenase and aldehyde dehydrogenase than a negative control group at concentrations of 100 μg/mL and 50 μg/mL, respectively. This study suggests that prenylated flavonoids have the potential to prevent ‘hangovers’ after alcohol intake.

      • KCI등재후보

        산양산삼약침의 지질강하 및 항산화효과에 대한 생화학적 및 분자생물학적 검토

        최은주,이준무,원승환,권기록,Choi, Eun-Ju,Lee, Joon-Moo,Won, Seung-Hwan,Kwon, Ki-Rok 대한약침학회 2006 Journal of pharmacopuncture Vol.9 No.1

        Objectives : This study was carried out to identified the effects of distilled cultivated wild ginseng pharmacopuncture to the obesity. Methods : Cultivated wild ginseng pharmacopuncture was administered on the points of chung-wan(CV12), $Ch'{\breve{o}}nch'u$(ST25), and Chok-samni(ST36) on lowering lipid and oxidative capacity in biochemical and molecular biological aspects were investigated in obese rats fed with high fat diet. Results : 1. The contents of plasma ${\beta}-lipoprotein$ showed a tendency to decrease in the pharmacopuncture groups compared to the control group. In the pharmacopuncture groups, the values of ST25 and ST36 pharmacopuncture groups showed lower value. 2. The contents of plasma free fatty acids showed a tendency to decrease in pharmacopuncture groups compared to the control group. However, in the pharmacopuncture groups, the values were not significantly different. 3. Plasma triglyceride and glucose showed lower value in the ST25 pharmacopuncture groups compared with the other groups. 4. The activity of AST showed a tendency to decrease in the pharmacopuncture groups. However, the activity of ALT was not significantly different in all the treatment groups. 5. Plasma total cholesterol and LDL-cholesterol showed lower value in the ST25 and ST36 pharmacopuncture groups and HDL-cholesterol showed higher value in the CV12 pharmacopuncture groups than that of the other treatment groups. 6. Liver total cholesterol values didn't show significant difference in all the treatment groups, and triglyceride showed lower value in the pharmacopuncture groups. 7. The contents of plasma TEARS showed lower value in the ST25 pharmacopuncture group and contents of liver TBARS showed a tendency to decrease in the pharmacopuncture groups. However these values didn't show significant difference in the pharmaco puncture groups. 8. Liver super oxide dismutase activity showed higher value in the ST25 and ST36 pharmacopuncture groups, and the value of liver glutathione peroxidase and catalase activity showed a tendency to increase in the pharmacopuncture groups. However, these values showed no significant difference in the pharmacopuncture groups. 9. Expression of apo-B and E mRNA in liver cells was lower in the ST25 pharmacopuncture group than that of the other treatment groups. However, expression of $TNF-{\alpha}$ and leptin mRNA in adipose cell showed no difference among all the treatment groups. 10. ST25 pharmacopuncture group showed a good histological character of liver. It showed similar to that of normal group. However other treatment groups and control group showed slight vasodilation and slight fat accumulation. Conclusion : These results indicate that distilled cultivated wild ginseng pharmacopuncture suppressed adipose tissue mass and lipid peroxidation, and increased antioxidant capacity.

      • KCI등재

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