Effects of Extrusion Conditions on Pasting Properties of Potato and Potato : Wheat Flour Mixture

Cha, Jae Yoon,Cho, Yong-Jin,Kim, Chong-Tai,Kim, Chul-Jin,Ng, P. K. W. 한국산업식품공학회 2003 산업 식품공학 Vol.7 No.2

The purpose of this study was to develop extrusion process of fresh potato and to study the effects of extrusion condition on the pasting properties of extruded potato products. The blend of pressed potato and wheat flour and pressed potatoes were extruded at different die exit temperatures (110-160℃) and screw speed of 100 rpm using a twin-screw extruder with conveying, high and low shear screw configuration. The viscosity-related parameters, such as peak viscosity, through, final viscosity, peak time, and pasting temperature of the feed materials and extruded products, were studied using a rapid visco analyzer (RVA). Their water solubility index (WSI) and water absorption index (WAI) were also studied. The peak viscosity, through, final viscosity, and peak time of pressed potato extrudates and potato-wheat flour mixture extrudates decreased as die exit temperature increased. The WSI and WAI of potato products increased as die exit temperature increased. When high shear screw configuration was used, the values of viscosity-related parameters were lower than those when low shear screw configuration was used. The potato-wheat flour mixture products obtained different degrees of depolymerization from fresh potatoes and wheat flour depending on die exit temperature and screw configuration.

신이식 환자에서 EBV감염과 관련된 악성 임파종 2예

윤선애,진동찬,김용수,신완식,윤영석,방병기,최영진,심상인,고용복 大韓移植學會 1993 Korean Journal of Transplantation Vol.7 No.1

張元素의 生涯와 醫學思想

金容辰,尹暢烈 대한한의학원전학회 1990 대한한의학원전학회지 Vol.4 No.-

Geum-Won dynasty is the era which totalized the every medical attainments of before Song dynasty and appeared some medical practioners who found new medical theory based upon this, and is important time for various developments of the oriental medical theory. At this time of the era, the representative practioners are called the four noted physician of Geum-Won dynasty. Jang Won-So who influenced the formation of the theory of the four noted physician of Geum-Won dynasty, originated new theory by joining the theory of 「Nae-Gyung」 with his own medical experience. The results can be summarized as follows after studying his life and idea of medicine. 1. Jang Won-So, courtesy name is Gyeol-Go, came from Yeog-Joo and it is unknown that when he was born and dead, but he lived in 11C. At 27, after failed in a Jin-Sa examination, he started medical study, and widely spreaded his medical art by healing the Yoo Wan-So's Sang-Han disease. 2. There are many Jang Won-So's writings, such as 「Eui-Hag-Gye-Won」 which is the condensation of his idea of medicine, 「Jin-Joo-Nang」 which is greatly contributed to development of Herbology, 「Jang-Boo-Pyo-Bon-Han-Yeol-Heol-Sil-Yong-Yag-Sig」 which is the sample of Jang-Boo-Byun-Jeung-Lon-Chi, and 「Yag-Joo-Nan-Gyung」 「Gyeol-Go-Ga-Jin」 「Gyeol-Go-Joo-Sug-Hwa-Mag-Myeol」 「Gyeol-Go-Bon-Cho」 「San-Yog-Bo-Sang-Bang」 which are known do not existing. 3. Jang Won-So's study about Jang-Boo-Byun-Jeung was influenced by 「Nae-Gyung」 「Jung-Jang-Gyung」 「So-A-Yag-Jeung-Jig-Gyeol」 etc. and outline by Han-Yel-Heo-Sil and the change and prognosis of the state of disease can be decided by Saeng-Sa-Yeong-Soon, so he contribute to development of Jang-Boo-Byun-Jeung-Lon-Chi of posterity. 4. Jang Won-So succeeded and develope the theory of the herbs of Oh-Jang-Go-Yog-Bo-Sa and about Ki-Mi-Seung-Gang-Boo-Chim etc. appeared on 「Nae-Gyung」, especially invented such as Kwi-Gyung-Lon, In-Gyeung-Bo-Sa-Seol, Jang Boo-Pyo-Bon-Yag-Sig and he enriched the content of pharmacological theory, so he motivated various development of herbalogical theory. 5. Jang Won-So's idea of On-Yang-Bi-Wi directly influence Lee Go's assertion of Bi-Wi-Lon, idea of Go-Geum-I-Gue-Seol presented theological basis of posterior medical practioners formation of prescription, so the way of drug usage greatly developed. 6. Jang Won-So's theory of the Jang-Boo-Byun-Jeung and herbology directly influenced to Lee Go, Wnag Ho-Go, Na Chen-Ik, Jang Byeok etc. so he became the father of Yeog-Soo class and indirectly influenced to Seol Gi, Jo Hen-Ga, Jang Gae-Bin, Lee Jung-Jae etc. of Myeng dynasty, so the On-Bo class has been formed. Like this, because, his idea of medicine developed at various aspect and greatly influenced to posterity, Lee Si-Jin said "Since the emergency of 「Nae-Gyung」, Jang Won-So is the only man who greatly enhance medical principle." so it is clear that this is not unfounded expression at all.

SELDI-TOF MS를 이용한 유방암 환자 진단을 위한 새로운 혈청 표지자의 개발

정용식,김호승,윤태일,전미선,윤용달,이용성,이기환,김혜진,김명욱,박희붕 한국유방암학회 2004 한국유방암학회지 Vol.7 No.1

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

한국의 대선진국 직접투자에 대한 소고: 구조적 시장방어론 : 가전산업을 대상으로

윤동진,전용욱 韓國國際經營學會 1991 國際經營硏究 Vol.2 No.1

개도국의 대선진국 직접투자는 흐름방향면에서 역투자로서의 의미를 지니며 전통적인 해외직접투자와는 그 특징이 상이하기 때문에 기존의 해외직접투자이론으로서는 그 설명이 어렵다고 할 수 있다. 본고에서는 한국제조업 중 대선진국 직접투자가 가장 활발한 가전산업의 해외투자를 분석한 결과 가전산업의 대선진국투자는 i) 독점적 우위의 부재, ⅱ) 방어적이고 생존적인 차원에서의 진출 ⅲ) 미성숙한 유형의 투자라는 특징을 가짐을 알아내고 이를 바탕으로 기존이론의 설명력 한계를 살펴본 다음, 대선진국 역투자를 설명할 수 있는 새로운 이론을 제시하고자 한다. 즉 한국가전산업의 역투자는 우리 경제의 성장구조적인 특징으로 인해 선택된 대량생산- 저가수출전략이라는 기존의 의사결정을 단기간내에 바꿀 수 없는 경직성으로인해 독점적 우위없이 불가피하게 이루어진, 수출시장보호라는 생산차원에서 내려진 구조적 시장방어행위임을 알 수 있었다. 이러한 특성으로 인해 가전 산업의 대선진국투자는 그 생명이 길지 못할 것으로 예상되므로 독점적우위확보, 글로벌 네투워크화, 전략적제휴 등을 통하여 이에 대한 대책을 마련해야 할 것이다.

低溫 鹽素化 反應에 依한 Silicon 製造

尹秉河,林龍進,金大龍,金圭鎬 경북대학교 공과대학 1980 工大硏究誌 Vol.9 No.-

The preparation of high purity silicon by the hydrogen reduction of sicl_4 which producted from the chlorination of commercial ferrosilicon was carried out. The chlorination rates and reaction ratio of ferrosilicon were increased with inoreasing of temperature and Cl_2 flow rate. The optimum Cl_2 flow rate and particle size of ferrosilicon was about 50ml/min and 30-40mesh, respectively. Reaction rate and reaction ratio were increased in the presence of NiCl_2, but CaCl_2, znCl_2, Cu powder and Cu-turnings were acted as an acticatalystic effects. By the addition of 10% NiCl_2 catalysis at 250℃, 66% reaction ratio for four hours was obtained. Silicon chlorides products were purified by the combination of the fractional distillation and silica gel adsorption techniques, and, using these purification techniques, all metallic and nonmetallic impurities were eliminated to unit ppm purified SiCl_4 was reduced in a graphite tube by hydrogen in the temperature range of 900-1200℃, The yields of the silicon products were increased with increasing of temperature and H_2/SiCl_4 mole ratio, and yields at 1100℃ and 1200℃ with mole ratio of 50 was 30% and 43%, respectively. Growth morphologies of silicon crystal were fine needle or cobweblike growth up to 1100℃ and coarse needle or sawtoothlike at 1200℃. These growth morphologies were little changed with precipitation substrates. The purity of silicon product which was analyzed after etching of HF and hydrochloric acid was higher than 99.99%.

대한상하수도학회 국제저명인사 초청간담회

윤제용,손진식 대한상하수도학회 2002 상하수도학회지 Vol.16 No.6

광굴절 매질을 이용한 칼라 패턴분류 시스템의 구현

윤진선,김남,전용성,정교일 충북대학교 컴퓨터정보통신 연구소 2000 컴퓨터정보통신연구 Vol.8 No.2

본 논문은 광굴절 매질(LiNbO3)을 이용한 칼라 패턴분류에 관한 연구이다. 광굴절 매질을 이용하여 모양 정보 뿐만 아니라 칼라 정보도 분류하는 시스템을 구현하였다. 칼라 패턴분류 시스템의 특성 실험으로서, 자기 상관 및 상호 상관 특성 실험을 수행하여 상관 세기를 비교 측정함으로써, 광굴절 매질을 이용하여 기록된 복소 공간 필터의 유사 판별 능력을 실험하였다. 광학 실험에서 렌즈의 초점거리는 250mm, He-Ne 레이저의 참조광의 각도는 11° , Ar 레이저의 참조광의 각도는 7°를 사용하여, R에 대한 상관결과는 원점으로부터 47.7mm. G에 대한 상관결과는 원점으로부터 30.5mm에서 각각 얻을 수 있었다. In this paper, the color pattern classification technique using a photorefractive material(LiNbO3) is proposed. The optical implementation to classify the shape and color distributions is realized. The discrimination capability of the color pattern classification system is examined against the similar patterns in the optical experiment for auto-correlation and cross-correlation tests. The correlation peak of red light is obtained at coordinates (47.7, 0) and the correlation peak of green light is acquired at coordinates (30.5, 0), when the focal length of the lens is 250mm, the reference waves of He-Ne laser and Ar laser are introduced at 11° and 7° respectively.

Midazolam의 백서 기관평활근 이완효과와 Flumazenil의 길항작용

윤석화,신용섭,손수창,이원형,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Midazolam have been used widely as adjuvants in both regional and general anesthesia and in high risk patients in the intensive care unit. In the present study we evaluated the effect of midazolam and antagonistic effect of flumazenil on isolated rat tracheal preparations mounted for recording isometric contractile force. Trachea smooth muscle were contracted with acetylcholine (10^-5M, Ach) and potassium chloride (40mM KC1). Midazolam 5x10 exp (-6)M and 5x10 exp (-5)M produced dose-dependent relaxation and flumazenil (3.2 x 10 exp (-7)M), central antagonist of benzodiazepine, pretreatment had no significant change midazolaminduced relaxation. Midazolam probably did not relax airway smooth muscle by activatong central benzodiazepine receptors, as flumazenil did not block the concentration-related relaxation of midazolam. Our study suggests that flumazenil may be used satety for asthmatic patients who have been with midazolam, as flumazenil did not antagonize airway relaxation elicited by midazolam.