Enhanced Densification and Hardness of Titanium Bodies Sintered by Advanced Hydrogen Sintering Process

Jung‑Min Oh,Ja‑Geon Koo,Jae‑Won Lim 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.6

A new sintering technique for enhancing a densification and hardness of sintered titanium body by supplying hydrogen wasdeveloped (Hydrogen Sintering Process, HSP). The HSP was developed by only injecting hydrogen into an argon atmosphereduring the core time. As a result, sound titanium sintered bodies with high density and hardness were obtained by the HSP. In addition, a pore size and number of the HSP specimens were smaller than those of the argon atmosphere specimen. It wasfound that the injecting hydrogen into the argon atmosphere by HSP can prevent the formation of oxide layers, resulting inenhanced densification and hardness.

산소유리라디칼이 뇌조직 미크로좀분획의 Na⁺-K⁺-ATPase 활성도에 미치는 영향

오세문(Sae Moon Oh)손영숙(Young Sook Son),최길수(Kil Soo Choi),임정규(Jung Kyoo Lim),정명희(Myung Hee Chung) 대한약리학회 1982 대한약리학잡지 Vol.18 No.2

중추신경계의 혈관폐쇄 또는 충격손상에 의한 허혈병소에서 진행되는 병리적 변화에 산소유리라디칼이 중요한 역할을 할 것으로 시사되고 있다. 저자는 산소유리라디칼이 뇌조직에 미치는 영향 중 특히 신경세포 정지막전위 유지에 중요한 Na⁺-K⁺-ATPase의 활성도에 미치는 영향을 관찰하기 위하여 산틴산화효소 반응계와 뇌조직미크로좀을 이용하여 본 연구를 시행하였다. 미크로좀분획(microsomal fraction)을 산틴과 산틴산화효소와 함께 반응시켰을 때, 분획의 Na⁺-K⁺-ATPase의 활성도는 현저한 불활성화를 보인 반면, Mg⁺⁺-ATPase의 활성도는 별로 영향을 받지 않았다. 이 불활성화는 산틴과 신틴산화효소 중 어느 한 물질이라도 반응계에 존재하지 않는 경우에는 나타나지 않았고, 두 물질이 같이 반응계에 존재할 때 나타났다. 산틴과 산틴산화효소의 반응에서 생성되는 산소유리라디칼들 중, 어떤 것이 Na⁺-K⁺-ATPase불활성화에 관계하고 있는가를 알아보기 위하여, 산수유리라디칼 각각에 대하여 제독작용을 가진 효소나 화학물질을 사용하여 불활성화의 저해유무를 관찰하였다. O^-₂⋅의 제독효소인 superoxide dismutase, H₂O₂의 제독효소인 catalase와 ¹O₂의 제독물질인 1,4-diazabixyclo(2,2,2)octane을 각각 사용하였을 때, 이들 물질들이 농도에 비례하여 Na⁺-K⁺-ATPase의 불활성화가 저해되었다. 그러나 OH⋅의 제독물질인 mannitol은 뚜렷한 효과를 보이지 못했다. 이상의 결과는 산소유리라디칼들 중 O^-₂⋅, H₂O₂ 및 ¹O₂가 Na⁺-K⁺-ATPase의 불활성화에 관계하고 있고, OH⋅는 거의 관계하지 않는다는 것을 시사하여 주었다. 이로 미루어, 산소유리라디칼에 의한 뇌조직 Na⁺-K⁺-ATPase의 불활성화는 뇌 허혈병소에서 관찰되는 신경세로의 기능적 장해를 유발시키는 한 요인으로 사료되었다. The effects of xanthine-xanthine oxidase reaction on brain microsomal Na⁺-K⁺-ATPase activity were studied to see possible involvement of oxygen free radicals in pathologic change occurring in ischemic state of CNS accompanied by cerebral vascular occlusion or impact injury. When microsomal fraction was incubated with xanthine ana xanthine oxidase, Na⁺-K⁺-ATPase activity of the fraction was markedly inactivated (80% inactivation) whereas btssl Mg⁺⁺-ATPase was much less sensitive (less than 10% inactivation) compared to that of Na⁺-K⁺-ATPase. The inactivation was observed only in the presence of both xanthine and xanthine oxidase, not either of them alone, and the extent of inactivation was dependent on the concentration of xanthine. In an attempt to determine which of the oxygen species was responsible for the inactivation, the ability of various scavengers to overcome the inactivation was tested. Superoxide dismutase, catalase and 1,4-diazabicyclo(2,2,2)octane were shown to reverse the inactivation of the ATPase in dose-dependent manner. In contrast, mannitol as well as other OH⋅quenchers were ineffective in limiting oxygen radical-induced inactivation. Thus OO^-₂⋅, H₂O₂ and ¹O₂ were implicated to be mediators involved in the inactivation. Since oxygen radicals are suspected as being a cause of the peroxidative damaging process in train ischemia, the ATPase inactivation by oxygen radicals may be a possible contributing factor which gives rise to functional derangement of nerve cells observed in the pathologic process.

외음부에 발생한 혈관근육섬유아세포종 1례

오혜근,구자봉,김동출,심재영,박정훈,박영균,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

We present a case of angiomyofibroblastoma of the vulva in a 32-year-old woman. The asymptomatic lesion measured 4×3cm and appeared as a gray-white myxoid mass on cut sections Histologically, it appeared as a relatively well-circumscribed spindle cell proliferation with alternating hypercellular and hypocellular areas and proliferation of thin-walled blood vessels. Immunohistochemically, the stromal cells expressed vimentin, CD34 and progesterone receptor, but not desmin, α-smooth muscle actin, S-100 protein and estrogen receptor. These features were similar to those of angiomyofibroblastoma as previously reported in the vulva except negativity for desmin A case of pathologically proven very rare tumor of angiomyofibroblastoma of the vulva is presented with a literature review

畵夜間 溫度差(DIF)處理에 의한 고추 '녹광' 플러그苗의 生長反應

임기병,오중열,정재동 慶北大學校農業科學技術硏究所 1996 慶北大農學誌 Vol.14 No.-

고추 '녹광' 품종의 플러그 육묘시 주야간 온도차 처리에 따른 생육조사 결과 초장은 주간온도와 DIF에 의해 영향을 받으며 절간장도 초장과 비슷한 경향이었다. 엽전개속도는 주로 일 평균 온도에 의해 좌우되었다. 엽장, 엽폭은 일 평균 온도가 증가함에 따라 증가 하는 것으로 나타났으며 생체중은 주야간 온도가 15℃처리구에서 가장 낮았고 일평균 온도가 증가함에 따라 증가하는 경향이었다. 생체중과는 반대로 엽록소함량은 일평균 온도가 15℃처리구에서 가장 높게 나타났으며 전체적으로는 야간온도가 증가할수록 엽록소함량이 저하되었다. 줄기직경은 DT/NT=15/15처리구에서 가장 낮았고 다른 처리구는 비슷한 경향이었다. T/R율은 DT/NT=30/15℃(+15DIF)처리구에서 가장 높게 나타나 지상부가 지하부에 비해 과번무됨을 알수 있었다. 따라서 녹광 고추의 플러그 육묘시 충실한 묘를 생산하기 위해서는 주간온도가 22.5℃, 야간온도는 15-22.5℃범위의 0DIF또는 약한 +DIF조건에서 육묘하는 것이 강건한 묘생산에 유리할 것으로 판단된다. Capsicum annuum 'Nokkwang' plug seedlings were treated with 9 different day and night temperatures to investigate on growth and differentiation in controlled environment conditions. The plant height was the most affected by day temperature and DIF and stem length was the similler results as plant height. However, Leaf unfolding rate and leaf length and width increased as average daily temperature increased. and especially fresh weight was worst at ADT was 15℃ and increased as ADT increased. In contrast with fresh weight, chlorophyll content calculated highest when ADT was 15℃, and decreased as NT increased respectively. The stem lengths were not significantly different among treatments with exception of DT/NT=15/15℃ which significantly decreased. The ultimate +DIF condition, DT/NT=30/15℃, caused high T/R ratio due to abundant top growth. It is concluded that DT is 22.5℃, caused high T/R ratio due to abundant top growth. It is concluded that DT is 22.5℃, and NT is ranged from 15℃ to 22.5℃ to be produced short, healthy plug seedlings in Capsicumannuum 'Nokkwang'.

활옷(豁衣)에 나타난 색상과 문양의 상징성에 관한 고찰

임현정,조오순 창원대학교 생활과학연구소 2003 생활과학연구 Vol.- No.7

Dress and ornament are native products of culture that can reflect certain and emotion of each times, particularly wedding dress is most brilliant and had variety implications in general. Woman's marriage ceremony puffer who wear in wedding is having very important meaning. Can lift Haw-Ot that is fortune of representative traditional wedding of our country. Among those wedding dresses for women in the public class, in the study, Hawl-Ot is discussed. Hwal-Ot is has beauty of peculiar form, color, pattern ect... and have each symbolism. Hwal-Ot was designed with patterns representing the very significance of wedding and those wishing worldly blessings more children and more sons, longevity and prosperity. Beyond just depiction or decoration of natural things, symbolic expressions were made into patterns based on a belief that there are spelling power in the wold to exert the absolute power unable of bing compared with human more ability.

건축설계과정에서 나타나는 협업프로세스에 관한 연구 : 파빌리온 설계사례를 중심으로

김정훈,김소희,임병민,김진아,송정화,오건수 남서울대학교 2007 남서울대학교 논문집 Vol.13 No.4

This study aims to deduce the effective collaborative process of architectural design process based on the specific pavilion design case. The study schematizes the collaborative procedure which is generated at the early stage of design process, analyzes the decision support system and suggests the method for reaching a compromise.Finally, this study suggested collaborative process method of architectural design and provided the basic concept that can be used for the similar projects. Keywords : Collaborative Design, Design Process

수종의 엔진구동형 니켈-타이타늄 파일에 의한 급한 만곡의 근관 성형시 근관형태 변화에 대한 비교연구

임중장,김동준,황윤찬,황인남,오원만 大韓齒科保存學會 2005 Restorative Dentistry & Endodontics Vol.30 No.4

본 연구는 치근첨부위의 급한 만곡을 가진 근관에서 엔진구동형 니켈-타이타늄기구를 이용해 근관 성형시 근관형태 변화에 대한 비교 연구를 함으로써 어떤 기구가 근관의 본래 형태를 잘 유지하는가를 구명하기 위하여 시행되었다. #15 finger spreader를 이용해 만곡된 근관의 주형을 형성하고 epoxy resin으로 모형 근관을 갖는 레진 블록 96개를 제작하였다. 모형 근관은 만곡의 반경이 0.5 mm, 3.0 mm.4.0 mm 및 6.0 mm를 가지며, 근관의 만곡도는 90도로 제작하였다. 엔진구동형 니켈-타이타늄 파일로 ProFile, ProTaper, Hero 642 그리고 K³를 사용하였으며 크라운다운법을 이용하여 제조회사의 지시에 따라 300 rpm으로 근관을 성형하였다. 시술 전·후사진을 디지털 카메라를 이용하여 촬영한 후, 이미지분석기를 이용하여 근관의 변화량을 측정하였다. 근관의 만곡을 따라서 치근첨 으로부터 1 mm 간격으로 계측점을 총 9부분을 설정하여 원래의 근관형태가 유지되는 정도를 측정하였다. 각 계측점에서 근관의 중심축의 변위량, 근관의 폭의 변화량을 측정하였다. 계측점에서 각 기구들간의 유의성은 Kruskal-Wallis 분석법을 이용하였고 기구간에 검정은 Mann-Whitney U-test분석법을 이용한 결과 급격히 만곡된 근관 성형시에 반경 1.5 mm의 만곡에서는 엔진구동형 니켈-타이타늄 파일을 사용시 주의를 요하며, 반경3.0 mm 이상의 만곡에서는 다른 엔진구동형 니켈-타이타눔 파일보다는 ProFile의 사용이 권고된다. The purpose of this study was to evaluate which type of Ni-Ti files are able to maintain canal configuration better in the simulated canal with abrupt curvature near it's apex. Ninety six simulated root canals were made in epoxy resin and #15 finger spreader was used as root canal templates. The simulated root canals were made with radius of curvature of 1.5 mm, 3.0 mm, 4.0 mm, 6.0 mm respectively and the angle of curvature of all simulated canals were adjusted to 90 degree. The simulated canals were instrumented by ProFile, ProTaper, Hero 642, and K³ at a 300 rpm using crown-down pressureless technique. Pre-instrumented and post-instrumented images were taken by digital camera and were superimposed with Adobe Photoshop 6.0 program. Images were compared by image analysis program. The changes of canal width at the inner and outer side of the canal curvature, canal transportation were measured at 9 measuring point with 1 mm interval. Statistical analysis among the types of Ni-Ti files was performed using Kruskal-Wallis test and Mann-Whitney U-test. The result was that ProFile maintain original canal configuration better than other engine driven Ni-Ti files in the canals above 3.0 mm radius of curvature, and in the 1.5 mm radius of curvature, most of Ni-Ti flies were deformed or separated during instrumentation.[J Kor Acad Cons Dent 30(4):303-311,2005]

유아놀이에서 나타나는 언어세계에 대한 의미 탐구

오정희,임부연 부산대학교 보육종합센터 영유아보육연구소 2008 영유아보육연구 Vol.14 No.-

Young children's world of language is fill with fresh and joyful sign. Play is one of the most significant context to reveal young children's language. This study attempts a phenomenological exploration on the meaning of children's language during play time. This study used phenomenological skills to observe 30 children's distinctive ability of using language during free play time in 5 year-old class at a kindergarten located in P city area. The data collected through 30 times of observation include observation note, in-depth interview with classroom teachers, and researcher's field note. The result showed that young children make rich the world of meaning to use and produce language in play time. The children knew what are the rule of play through insight and they create rules of play. They were also able to deconstruct and reconstruct signs by using imagination and metaphor which are the most powerful symbol of consciousness in early childhood period. This study discussed that early childhood teachers should be more careful to listen and respect children's own language which is not a measure of development or fuction but an expression of inner world.

경피내시경하 위루술(PEG)을 시행한 중풍후유증 환자 1례에 대한 증례보고

임승민,안정조,최영,조현경,오병렬,설인찬 대전대학교 한방병원 2002 惠和醫學 Vol.11 No.1

According to the case study of patient with seguela of C.V.A who was treated by Percutaneous Endoscopic Gastrotomy(PEG), his chief complaint is the dysphagia. We treated him by a viewpoint of oriental medicine and got the good clinical symtom.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.