들잔디 성숙종자로부터 캘러스배양 및 식물체 재분화에 미치는 몇 가지 요인의 영향

이상훈,김범수,원성혜,조진기,김기용,박근제,성병렬,이효신,이병현 Plant molecular biology and biotechnology research 2004 Plant molecular biology and biotechnology research Vol.2004 No.-

In an effort to optimize tissue culture responses of zoysiagrass (Zoysia japonica Steud.) for genetic transformation, factors affecting callus induction and plant regeneration were investigated. MS medium containing 3 ㎎/L 2,4-D was optimal for embryogenic callus induction from mature seed. The plant regeneration frequency of 73.3% was observed when embryogenic calli induced in this medium were transferred to N6 medium supplemented with 0.1 ㎎/L 2,4-D and 5 ㎎/L BA. Among several basic media, MS and N6 medium were optimal for callus induction and plant regeneration, respectively. Regenerated plants were grown normally when shoots transplanted to the soil. A rapid and efficient plant regeneration system established in this study will be useful for molecular breeding of turfgrass through genetic transformation.

다산부에서 자간전증의 임상적 고찰

이주롱,이석민,한효상,이해혁,이임순,이권해 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

목적 : 전자간증 산모에서 초임신부와 다산부 각각의 임상적 특징을 조사하여 비교 분석하고자 하였다. 연구방법 : 1998년 1월부터 1999년 12월까지 2년간 순천향대학 서울병원에서 입원 분만한 임신성 고혈압성 질환 환자중 초임신부 106명과 다산부 50명, 총 150명을 대상으로 임상통계학적으로 조사 분석하였다. 결과 : 분만까지 임신기간의 비교시 초임신부에서는 33-36주에서 17.9%였고 다산부에서는 34.0%로, 다산부에서 조기분만의 예가 의의있게 많았다. 신생아 체중이 2500g 미만인 군이 초임신부군에서는 36.8%였고 다산부군에서는 62.0%로 다산부군에서 더 많았다. 임신성 고혈압성 질환의 중등도를 보면 중증자간전증의 초임신부에서 35.8%와 다산부에서는 44.0%로, 초임신부에 비해 다산부군의 중증 자간전증의 비율이 많았다. 결론 : 중증 임신성 고혈압성 질환이 다산부군에서 더 많았으며 적은 주수에서 제왕절개술을 시행해 출생아의 체중이 초임신부군에 비해 더 작았고 Apgar 점수도 더 낮았다. Objective : To study the clinical differences of primiparous and multiparous preeclamptic patients. Methods : We statistically analyzed 106 primiparous and 50 multiparous preeclamptic patients who were admitted to the Soonchunhyang University Hospital from January 1998 to December 1999. Results : It was statistically found that multiparae were more likely to give premature birth than primiparae: Thirty four percents of multiparae gave birth in the period between the 33rd and the 36th gestational weeks while 17.9% of primiparae did in the same period. Sixty two percents of the newborn babies of multiparae weighed less than 2500g. Among primiparae, the ratio was 36.8%. In addition, more multiparae(44.0% vs. 35.8%) suffered from severe preeclampsia. Conclusion : severe preeclampsia was found more frequently among multiparae. Since they gave birth earlier by cesarian section than primiparae, their babies weighed less and had lower apgar scores.

집적화된 실리콘 압력센서의 출력전압 보상파라미터 추출 및 그 특성

이보나,김건년,박효덕,신상모,이경탁,김찬,권혁채,이상조,박현주 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

An integrated silicon pressure sensor has been designed, fabricated and tested. The signal conditioning circuits were designed to include calibration and temperature compensation of output voltage through trimming of diffusion and ion-implanted resistors. Before trimming of resistors, the compensation parameters such as pressure sensitivity, temperature coefficient of pressure sensitivity, temperature coefficient of piezoresistors and pressure sensitivity of piezoresistors were measured. Then offset voltage, span, and temperature coefficients of offset voltage and span were calibrated by trimming of resistors. The measured output voltage met our design specification and simulation value above room temperature. But, the measured output voltage at -30°C deviated from our design specification and simulation value because the offset voltages were found to vary randomly as a function of temperature.

Novel Methylation Biomarker for Non-invasive Diagnostics in Lung Cancer

오태정,( Chang Hun Lee2 ),( Min Ki Lee ),( Yeul Hong Kim ),( Sang Yull Lee ),( Hyo Sung Jeon ),( Shin Yup Lee ),( Seung Soo Yoo ),( Jae Yong Park ),( Sung Whan An ) 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-

To identify aberrantly hypermethylated DNA in lung cancer cells we established a genome-wide analysis for hypermethylation sites, namely Methyl DNA Isolation and Amplification (MeDIA) coupled-CpG microarray analysis. In the comprehensive methyaltion profiling analysis between human lung cancer, A549 cells and normal NHBE cells, we observed that several clusters of genes show a significant level of aberrancy in CpG island methylation pattern in cancer cells compared to normal cells. We further identified PCDHGA12 gene as a new marker of non-invasive diagnostics for lung cancer based on followings. 1) Transcription of PCDHGA12 gene is reactivated after treatment of A549 cells with demethylating agent. 2) Bisulfide clonal-sequencing reveals that CpG island of PCDHGA12 shows a distinctive differential methylation between two cell lines. 3) Pyrosequencing-based quantitative methylation assay for such region in tumor and non-tumorous tissues from lung cancer patients shows aberrant hypermethylation in 37 (92%) of the 40 tumor tissues. In clinical validation by pyrosequencingin induced-sputum of lung cancer patients (n=87) and healthy controls (n=51), we observed aberrant hypermethylation incident at significantly elevated level in samples derived from lung cancer patients. According to the optimal threshold calculated by ROC curve analysis, sensitivity and specificity of PCDHGA12 was 86.2% and 82.4%, respectively. PCDHGA12 methylation status could be a potential methylation biomarker alone or combined with others for the screen and the detection of relapse of lung cancer.

궤양성대장염 환자와 과민성대장증후군 환자의 감정표현불능증 비교 연구

이상빈,이성용,김상헌,임효덕 한국정신신체의학회 2003 정신신체의학 Vol.11 No.1

기계적 합금화에 의한 Cr-N계 합금분말의 합성연구

이충효,이상진 木浦大學校 應用科學硏究院 2001 應用科學硏究誌 Vol.1 No.-

Mechanical alloying(MA) by high energy ball mill of pure chromium powders was carried out under the nitrogen gas atmosphere. Cr-N amorphous alloy powders have been produced through the solid-gas reaction subjected to MA. The atomic structure during amorphization process was observed by X-ray and neutron diffractions. An advantage of the neutron diffraction technique allows us to observe the local structure surrounding a nitrogen atom because of a large coherent scattering length of the N atom in comparison with that of the Cr atom. The coordination number of metal atoms around a N atom approaches with 5.5 atoms. This implies that the nitrogen atom is located at both of centers of the tetrahedron, octahedron and/or trigonal prism formed by metal atoms to stabilize the amorphous structure.

進饌儀軌 卷之一

이성우,이효지 漢陽大學校 韓國生活科學硏究所 1985 韓國 生活 科學 硏究 Vol.- No.3

경호업무 수행을 위한 용무도(龍武道) 수련방법 연구

이상철,김의영,김의영,한창효 龍仁大學校 武道硏究所 2002 武道硏究所誌 Vol.13 No.1

This study focuses on reestablishing martial arts and sports education based on existing educational capabilities in Korean martial arts education to facilitate the localization of Korean culture around the world. Furthermore, the study intends to globalize our own martial arts and apply Yongmoo-do practices to different guard situations, which were originally developed on a great ambition to enhance the position of Korean martial arts in the 21st century as the beginning of new millennium. Guard or escort exists for just a moment which implies accidental emergency. Upon any occurrence of such emergency, the success of guard duty depends on how much rapidly and safely clients can be protected. Therefore, a bodyguard or escort who performs guard duty could face a variety of accidental emergencies so that they must be usually trained with proper martial arts in various way. Yongmoo-do is designed to enable bodyguards to safely deal with unexpected accidents by practical martial skills such as strike, kick, throws(mechigi), snap, neck wring and other skills using weapon. In addition, Yongmoo-do also allows guards to raise their defense capability and survivability against accidental threatening attacks from any suspicious criminal. As described above, it is noted that Yongmoo-do has high applicability enough to meet both safety and self-defense requirements. Thus, it is expected that Yongmnoo-do practices will facilitate trainees to master its theories and phased basic skills so that they can be trained in scheduled and formulated ways based on countermeasures and guard/escort techniques against any occurrence of emergency. Moreover, they will be likely to feel more actuality through an approach of guard martial art according to harmful elements under the simulated guard formation by different situations.

최근 10년간 조선대학교 치과병원 소아치과에 내원한 신환에 관한 역학적 연구(1990-1999)

이창섭,류현섭,김효석,이상호 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.3

본 연구는 소아환자들의 변화하는 특성을 파악하고 이해함으로써 환자나 보호자와의 적절한 의사소통을 위한 자료나 정보 제공을 용이하게 하며 , 적절한 진단과 치료계획을 수립하는 데 도움을 주며 , 또한 국내 다른 지 역을 중심으로 한 연구와 비교 분석하여 이 지방의 소아환자의 치료의 방향성을 설정하기 위해 본 연구를 시행하였다. 이를 위해 1990년 1월 1일부터 1999년 12월 31일 까지 조선대학교 부속치과병원 소아치과에 내원한 모든 신환아동을 대상으로 하여 분포와 변화추세를 조사 연구한 결과 다음과 같은 결론을 얻었다. 1.내원환자의 수는 56년 이후 증가 추세이며, 남자가 55.9%, 여자가 44.1%로 남자가 여자보다 많은 비율을 보였다 (P>0.05) . 2. 연령별 분포에서 3∼4세 군의 내원율이 23.4%로 가장 높게 나타났으며 5∼6세 군이 19.9%, 7∼8세 군이 17.7%,0∼2세 군이 14.6%순 이었다. 3 내원환자의 거주지 분포에서 광주시내 거주자가내원환자의 83.0%로 대부분을 차지하였고,근거리 광주시외 거주자는 5.4%를 보였다 4.내원환자의 주소(chiefcomplaint)별 분포에서 충치 치료를 주소로 내원한 경우가 40.5%로 가장 많았고, 구강검진이 13.9% , 교정적 문제가 12.6%를 보였다. 5.외상을 주소로 내원한 환자중 치관 파절이 41.4%로 가장 많았고, 아탈구가 19.4%, 진탕이 12.0%. 완전탈구가 11.4% , 함입이 9.3%를 차지하였다. 6.내원동기의 분포는 의뢰되지 않은 경우가 78,7%를 차지하고, 의뢰된 경우 중 치과의원에서 의뢰된 경우가 전체의 20.5%이고,치과의원에서 의뢰된 경우 중 진료의 난이도 때문이 12.7%,행동조절의 어려움 때문이 6.2%를 나타냈다. 7. 주기적인 검사가 되는 환자가 전체환자의 19.6%를 차지하였고, 그 중 3개월 후가 36.7% , 6개월 후가 22.2% , 9개월 후가 13.5%를 나타냈다. The purpose of this study was to make public oral health plan more effective and the improvement of the hors-pital management system for better clinical dental practice. Distribution and trends were examined in all patients who had been examined and diagnosed at Department of Pedodontics, Dental Hospital, Chosun University over 10 year-period from 1990 to 1999 Results were as follows, 1.The number of patients per year was increasing trend after 1996 and higher visiting rate in male(55.9% ) than in female(44.1%). 2.Age distribution had shown 3∼4 year-old group being the largest (23.4% ) and each percentage of 5∼6, 7∼8,0∼2. 9∼10. 11∼12, 13∼14. above∼15 year-old group was 19.9%, 17.7%, 14.6% 12.6%, 8.0%, 3.3%, 0.5%. 3.Geographic distribution showed a majority of patients in Kwang-Ju (83.0%) . Group in the suburbs of Kwang-Ju (Jang-Sung group) was 5.4%. 4.Dental caries showed the highest percentage(40.5%) in chief complaints and percentage of oral exam, orthodontic problem, oral pain, trauma. supernumerary teeth, swelling was 13.9%, 12.6% . 8.8%. 7.4% , 5.5%,4.9% 5.In all patients with traumatic problem, crown fracture showed the highest percentage(41.4%) and percentage of subluxation was 19.4%. 6 Majority(78.7% ) of patients were not refired, and percentage of patients refered from local clinic was 20.5%. 7 Patients who had periodic check-up comprised 19.6% , and percentage of after 3, 6, 9. 12, 18,24month was 36.7%,22.2%, 13.5%, 11.3%,5.4%, 11.0%.

DCT를 이용한 정지화상의 효과적인 DC계수의 부호화

이성필,김태효 慶南大學校 附設 工業技術硏究所 1993 硏究論文集 Vol.11 No.-

최근 JPEG(Joint Photograph Expert Group)이 변환부호화기술을 이용한 정지화상의 부호화 알고리즘을 국제표준의 권고안으로 내 놓았다. JPEG시스템에서는 현재 블럭의 DC계수를 예측하기 위해 이전블럭의 DC계수를 사용하여 간단한 1-D 예측기를 이용한 DPCM(Differencial Pulse Coded Modulation)으로 부호화된다. 본 논문에서는 블럭엣지차분(Block Edge Difference, BED)예측기가 기본 JPEG시스템의 성능을 개선하기 위해 제안되었다. BED예측기는 현재블럭의 DC계수를 예측하기 위해 인접하고 있는 블럭들 사이의 엣지차분정보를 이용한다. 제안된 BED예측기가 JPEG예측기보다 DC계수를 더욱 효과적으로 부호화할 수 있음을 확인하기 위해 통계적 모델에 의한 분산해석을 하였고, 또 실제화상을 이용한 컴퓨터 시뮬레이션에서 제안된 BED예측기를 사용했을 때 기본 JPEG예측기보다 약 5% 이상의 비트율(bit-rate)의 압축효과를 얻을 수 있었다. Recently, an international standard, JPEG algorithm is proposed for still image coding using the technique of discrete cosine transform(DCT). In JPEG scheme, in other to predict the DC coefficient of current block, the DC coefficient of the previous block is used by a simple 1-D predictor of DPCM. In this paper, a block edge difference(BED) predictor is proposed to improve the performance of the basic JPEG system. The BED predictor uses the block edge difference between adjacent blocks for prediction of the current block. A statistical variance analysis shows that the BED predictor can encode the DC coefficients more effectively than the JPEG predictor. Computer simulation using real test images also shows that when the proposed BED predictor is used, it is obtained about 5% bit-rate compression over the basic JPEG predictor.