한국의 정신분열병 외래 환자의 직ㆍ간접비용

박종익,송선희,서동우,장현종,이종국,장안기,김윤,이철,홍진표 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.3

연구목적 : 정신분열병 외래 환자의 직접 비용과 간접 비용을 추산해 보고, 의료 자원의 적절한 운용과 효과적인 배분을 위한 보건 정책의 기초자료로 사용하고자 한다. 방 법 : 정신분열병 진단을 받은 289명의 환자를 대상으로 6개월간 외래를 방문하면서 사용한 의료비와 시간을 조사하여 직접 비용을 추산하였고, 이 기간 동안 소실된 생산성을 간접 비용으로 환산하였다. 만성질환인 관상동맥 질환을 앓고 있는 환자 82명을 대조군으로 하여 비용을 비교하였다. 결 과 : 정신분열병 환자의 실업률은 72.1%였으며, 직장을 가지고 있는 경우에도 단순노무직의 비율이 64.5%로 매우 높았다. 정신분열병의 직접 비용은 평균 81.5만원으로 관상동맥 질환의 평균 71.5 만원보다 상대적으로 많이 추산되었으나 유의하지는 않았다. 간접 비용은 평균 645.6만원, 258.9 만원으로 정신분열병군이 2.5배 정도 높았다. 결 론 : 정신분열병은 다른 만성질환에 비하여 상대적으로 매우 고비용이 요구되는 질환이며, 보다 체계적인 비용의 추산을 통하여 양질의 정신 보건 서비스를 제공할 수 있는 토대가 마련되어야 할 것이다. Objectives : We have aimed to estimate the direct and indirect costs of treating out-patients with schizophrenia in Korea, to use this fundamental data for the effective management and proper distribution of the medical resource. Method : To estimate the direct cost, we surveyed the medical cost and time of two hundred and eighty-nine out-patients with schizophrenia for six months. And the lost productivity as many months was converted into the indirect cost. Those of eighty-two coronary heart disease patients were also estimated as a comparison group. Results : An unemployement rate of schizophrenic patients was 72.1 percent. Moreover the ratio of the laborer in the sample was, even if employed, 64.5 percent. The mean direct cost of schizophrenic patients was, about 815,000 won, higher than that of coronary heart disease, 715,000 won however it was not statistically significant. The former was also estimated 2.5 times more than the latter for the indirect cost, or 6,456,000 won versus 2,589,000 won. Conclusion : Schizophrenia is a relatively costly illness compared to other chronic illness, so the systematic estimation of the cost is necessary to provide mental health service of high quality.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

남성유방에 발생한 지방육종

최종범,임성철,기근홍,전호종,서재홍 대한병리학회 1992 Journal of Pathology and Translational Medicine Vol.26 No.3

Triple X 증후군(47,XXX) 환자에서의 강박장애 1례

김종훈,진영호,장기용 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

Triple X 증후군은 비교적 드물게 나타나는 성염색체이상증후군으로 아직까지 특정 정신병리현상과의 연관성은 충분히 알려져 있지 않은 상태이다. 본 저자들은 핵형 분석으로 검증된 47, XXX triple X 증후군에서 강박장애가 동반된 증례 1례를 경험하였다. 환자는 불완전한 성적발달, 내분비적 이상, 무월경과 함께 복합적인 강박증상, 강박행동을 나타내었다. 뇌자기공명영상촬영 결과 환자의 좌측 후두엽피질하 백질 부위에서 고신호 광도 병변이 관찰되었다. 환자의 강박증상, 강박행동들은 고용량의 fluoxetine과 buspirone약물요법 및 인지행동치료에 부분적 반응을 보였으나, 환자의 전반적인 심리 사회적 기능은 치료후 크게 호전되었다. 본 증례 및 관련문헌에 대한 고찰을 통해, 본 저자들은 triple X 증후군과 같은 X염색체의 이수배수체질환(X chromosome aneuploidy)이 강박스펙트럼장애(obsessive-compulsive spectrum disorders)혹은 강박장애에 취약할 가능성이 있음을 제시하고자 한다. Triple X syndrome is a relatively rare sex chromosomal anomaly, and its association with psychopathology is not well understood. The authors report one case of obsessive-compulsive disorder(OCD) with karyotype-confirmed triple X syndrome, 47, XXX. She had incomplete sexual development, secondary amenorrhea and multiple obsessive-compulsive symptoms. Magnetic resonance imaging of the brain revealed left occipital white matter hyperintensity lesion. The patient's multiple obsessive-compulsive symptoms were responded partially with fluoxetine and adjunctive buspirone treatment, however, her overall psychological functions were much improved. With the literature reviews, the authors suggest the possibility that a certain type of sex chromosome aneuploidy might be susceptible to obsessive-compulsive spectrum disorders(OCSDs) or ODC.

蛇行河川에서의 흐름特性 : 準蛇行形 및 一定曲率形 水路中心으로 Flow Analysis in the Sinouos Channel and Constant Curvature Channel

車英基,이종석 단국대학교 1993 論文集 Vol.27 No.-

This paper is a model of the calculation of flow field and bed topography for sinuous channels and constant curvature channels with erodible beds. A small perturbation approach is used to linearize the governing equations as equations describing the flow field and the bed topography. The model predicts satisfactorily the secondary flow and the transverse bed slope. The model of Kitanidis and Kennedy(1984) was shown to highly overpredict the magnitude of the secondary flow. By comparsion with laboratory and field data it is shown that our flow model gives substantially better results than the other models.

數種의 글라스 아이오너머 修復材의 弗素 遊離量과 修復物 邊緣 琺瑯質에 吸收된 弗素 含量에 관한 硏究

김종수,손일수,김용기 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

In this study, various kinds of glass ionomer filling materials were evaluated for fluoride release and uptake by adjacent enamel. Fuji Ⅱ, Ketac-Fil, Ketac-Silver were used for this study and Silux plus was selected for control group. Measurements of fluoride concentration released in solution from discs made of selected materials were performed daily for the first 7 days and on the 14th, 21st day after the experiment. In order to evaluate the amount of fluoride uptake by enamel adjacent to restorations, pre-op and post-op enamel biopsy were done on every sample teeth. Ketac-Fil showed the highest amount of fluoride release among tested materials through whole experimental periods. Statisically significant differences between pre-op and post-op enamel fluoride concentration could be found in Ketac-Fil from the first week and in Fuji Ⅱ from the 2nd week after fillings.

Ni_1-xFe_x 박막의 자기저항효과에 관한 연구

김종기,정진봉,백주열,이기암 단국대학교 신소재기술연구소 1993 신소재 Vol.3 No.-

DC Magnetron Sputtering 법으로 제조된 Ni_1-xFe_x 박막에 대해 박막의 두께 및 시편의 조성비가 자기저항비에 미치는 영향에 대하여 조사하였다. 시편의 조성비는 Fe chip의 개수로 조정하였으며, 박막의 두께는 400∼1600Å으로 변화시켰다. 복합타겟의 구성방법은 개량된 모자이크방식이었고, 자기저항비는 4-point probe를 이용하여 측정하였다. Fe의 조성이 증가함에 따라서 자기저항비는 증가하였으며, 조성이 x≒11에서 최대가 되었고, 두께가 증가함에 따라 자기저항비도 증가하였다. 제작된 모든 시편은 비정질구조를 나타내었다. We have investigated the magnetoresistance ratio on the influence of film thickness and range of sample composition about Ni_1-xFe_x Thin Film produced by DC Magnetron Sputtering. The range of sample composition was controlled by the number of Fe chips, and the range of deposited film was 400Å to 1600Å. Target formation was the improved mosaic type, and magnetoresistance ratio measured by 4-point probe method. The magnetoresistance ratio was increased with the increase of film thickness, and the magnetoresistance ratio was varied with sample composition. All samples were showed amorphous structure.

공간 데이터베이스에서의 연속 클래스 및 설명 기능

박종석,이준호,이기철 弘益大學校 科學技術硏究所 1999 科學技術硏究論文集 Vol.10 No.1

Recently, spatial data mining has become an important area as geographic information systems are affecting people more in many areas. In the past decade, knowledge extraction from raw data has been extensively studied. How to utilize the data mining technique for building a spatial data mining system is suggested in this paper. Especially, descretization of class attribue may affect the quality of the system, and after decising a partner attribute, we repeatedly re-discretized the class attribute and partner attribute alternately until no more recognition rate is improved. Also, we suggested a general query form which may be used in most spatial mining domains. The experimentation has been performed on TIGER data to prove the stability of our method.

Southern Blot Hybridization법을 이용한 악성 림프종의 면역유전형에 관한 연구

전호종,기근홍,김윤신,이미숙,이미자,장원재,장숙진,박영진,정춘해,정종훈,양성훈,이광민 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Immunogenotyping using gene rearrangement analysis has emerged as a precise laboratory aid in the diagnosis and classification of malignant Iymphoid neoplasms. The lineage and clonality of the malignant Iymphoid neoplasms can be identified by the demonstration of rearrangements of antigen receptor genes of the immunoglobulin and T-cell receptor genes. The analysis of the gene rearrangements on the malignant Iymphoid neoplasms are also useful as a sensitive unique clonal markers to detect early recurrence in patients with malignant Iymphoid neoplasms after treatment. To analyze the sensitivity and specificity of gene rearrangements in the diagnosis of malignant Iymphoid neoplasms. 24 cases of malignat Iymphoma were examined by Southern blot hybridization using CTβ-T cell receptor β chain gene-DNA probe and JH-immunoglobulin heavy chain gene-DNA probe. The results of the immunogenotypings using Southern blot hybridization disclosed high correlation between the immunophenotyping using immunohistochemical stain with monoclonal antibodies (B-cell Iymphoma 84.2%. T-cell Iymphoma 75% ). The analysis of the gene rearrangement of the angioimmunoblastic lymphadenopathy(AILD) and unclassifiable Iymphoma using immunohistochemical stain could resolve the monoclonality and lineage . Rearranged bands to the CTβDNA probe were observed in one case out of 2 cases of AILD. One case of unclassifiable Iymphoma showed rearranged bands to the CTβ DNA probe. There were no rearrangements in reactive follicular Iymphoid hyperplasia and paracortical Iymphoid hyperplasia. In conclusion, DNA gene rearrangement study should be applied to differentiate the clonality and cell lineage in the malignant Iymphoma with indistinctive immunophenotype.

인텔리젠트 빌딩의 安全시스템에 關한 硏究

김종배,이동기 대구산업정보대학 1994 논문집 Vol.8 No.-

After passing through both agricultural and industrial phase, today society, due to technological revolution is becoming highly information oriented. This has resulted in the need for greater amounts of information in all fields of society. In step with this trend, office automation, home automation and factory automation are being promoted extensively. In turn these tendencies have been the main cause of grand scale disasters and the problem of ensuring safety in buildings has manifested itself as a problem for the whole society. However at present in most buildings the fire-fighting facilities and supervisory equipments are usually set-up separately, trailing greatly in areas of safety and efficency. Although there are numerous methods for improving security in office buildings, this study will focus on Intelligent Building and ultimately try to reach the goal of ensuring safety in buildings through interconnecting security systems with intellectualization of buildings. Untill now security systems were usually set-up and operated apart from the central supervision and control department which oversees and regulates the electricity, air conditioning, sanitary facilities and so on. But in Intelligent Buildings central supervisory, control system is introduced in which fire-fighting, crime prevention facilities, electricity, air conditioning, comunications devices and so on are all inter-connected organically, and thus each facility is comprehensively intergrated and interlocked. From the above viewpoint, planning of a system best suited to the requirements which have taken into consideration future usage and expansion on the basis of extensive professional knowledge and experience, must be the preconditions for the fulfillment of Intelligent Building with its highrate safety capabilities.