서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

RAPD와 핵 리보솜 DNA ITS2 염기서열에 의한 한국산 전나무속 식물의 유전적 변이 및 계통유전학적 분석

정용환,한상현,오유성,고미희,고석찬,김문홍,오문유 濟州大學校 基礎科學硏究所 2001 基礎科學硏究 Vol.14 No.2

We analyzed the genetic variation and phylogenetic relationship among fourteen taxa of GenusAbies distributed in Korea using random amplified polymorphic DNA (RAPD) and internal transcribed spacer (ITS) 2 sequences of the nuclear ribosomal DNA (rDNA). RAPDs were used for identification of selected taxa by amplification using single 10-mer primers of arbitrary sequence. Fourteen taxa were clearly classified with 10 arbitrary primers, which generated 102 useful polymorphic bands that were evaluated according to the presence or absence of the fragments of equal size. The genetic distance between A. koreana for. chlorocarpa and A. koreana for. rubrocarpa was 0.127, showing the closest among any other pairs. By comparing the base sequences in the ITS2 region of the nuclear rDNA, genetic relationship was assesed among selected taxa. It showed twenty six sites of point mutation (base substitution) in 243 base pairs (bp) of ITS2 region. The G+C contents of ITS2 region were ranged from 58.3% to 61.7%. The value of nucleotide divergence among selected taxa was ranged from 0.4% to 9.8%. These results showed that RAPD and ITS2 sequence analysis was a useful tool for elucidating phylogenetic relationship and selection of specific marker in Abies species.

활동혈압에 의한 Cicletanine의 강압효과 판정

정태기,김현대,류재춘,최석구,유원상 인제대학교 1993 仁濟醫學 Vol.14 No.4

Prostaglandin 합성을 촉진하는 새로운 강압약인 cicletanine의 강압효과를 진료실 혈압과 24시간 활동혈압으로 평가했을 때 상당한 차이를 보여 그 이유를 검토해 보았다. To evaluate antihypertensive effect of cicletanine with both clinic and ambulatory blood pressure monitoring, 10 male hypertensive patients were administered cicletanine, a new antihypertensive stimulating prostaglandin synthesis, in 100∼200 mg daily for 12 weeks. The following were the results. 1.Mean of clinic BP decreased from 161/98 mmHg to 153/98 mmHg. 2.Mean of ambulatory BP changed from 140/91 mmHg to 153/99 mmHg. 3.Side reactions were mild, namely indigestion and constipation. 4.Discrepancy between clinic and ambulatory BP were discussed. In conclusion cicletanine revealed slight antihypertensive effect with clinic blood pressure, but failed to confirm it with ambulatory blood pressure.

體型과 有·無酸素的 運動能力에 關한 硏究

鄭石珍,金武泳 全北大學校 敎育大學院 1982 敎育論叢 Vol.2 No.-

Fifty randomly sampled male students (mean age 19 years) at Jeonbug National University in Jeonju city served as subjects in this study. These students were divided into three groups of 5 endomorphs, 36 mesomorphs, 9 ectomorphs according to Heath-Carter's anthropometric method. The one hundred meter dash and 2,000 meter distance run were adopted to measure aerobic and anaerobic motor ability respectively. To determinethe relationship of somatotype to motor ability and the differences of motor ability among somatotype groups, statistical analysis were used. The findings of this study are as follows: 1. The mean somatotype of college freshman was ectomesomorph. 2. Low realtionships existed between the first components of somatotype and aerobic and anaerobic motor ability. 3. The second and the third somatotype components were not related to erobic and auaerobic motor ability. 4. There were significant differences between aerobic and anearobic motor ability among somatotype groups. 5. Mesomorphs were superior to other endomorphs and ectomorphs in track records.

韓國에 있어서의 먼지진드기에 關한 硏究

康晳榮,朱鼎均 대한의학협회 1975 대한의학협회지 Vol.18 No.12

韓國에 있어서의 우렁?이 알레르기에 關한 硏究 : 韓國에 있어서의 職業性 알레르기硏究 第1報 Studies on the Occupational Allergic Disease in Korea Report Ⅰ

康晳榮,朱鼎均 대한의학협회 1976 대한의학협회지 Vol.19 No.11

자이로 안정화 플랫폼의 정밀제어를 위한 적응 마찰 보상

윤석영,박정일 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.1

This paper presents a new adaptive friction compensation technique for stabilized platform of a first order plant with nonlinear friction. Nonlinear friction torque is a major source of tracking and stabilization error in precision pointing servo systems. The proposed compensator is composed of nonlinear feedback controller and reference model of a plant without torque friction. Gains of friction compensator are adaptively adjusted to variation of the friction torque of plant. Simulation result shows that the proposed compensator can significantly reduce the nonlinear factors.

생물막 유동층 반응기에서의 미생물 농도 예측

추석열,서정호,박태주,김동석,송승구 부산대학교 환경문제연구소 1991 環境硏究報 Vol.9 No.-

This experiment was carried out to predict biomass concentration of attacted biofilm and to investigate fluidized-bed biofilm reactor (FBBR) performance of treating high organic loading rate. A number of experiments were conducted by increasing organic loading rate from 10kgCOD/㎥·day to 80kgCOD/㎥·day with superficial upflow velocity, 0.47cm/sec, operationg temperature, 22±1℃ and pH, 7±0.1. Glucose was used as a synthetic substrate. COD removal efficiencies were remarked as 73 to 96%, and the biomass concentration was increased up to 37,000mg/1. Under this experimental conditions, the FBBR was most efficiently operated at the F/M ratio of 1.7 and the biofilm thickness of 420㎛.

키틴 분해균 Bacillus sp. LJ-25의 분리 및 효소생산 최적화

이정석,주동식,조만기,이응호 동서대학교부설연구소 1997 연구소 논문집 Vol.2 No.-

In order to produce functional chitin oligosaccharides, a chitinolytic becterium was newly screened from the viscera of Korean bony fish, and identified as Bacillus sp. LJ-25. For the production of chitinolytic enzyme, 1.0% nutrient broth and 0.3% colloical chitin was used as nitrogen and carbon source, respectively. The optimal temperature, initial pH and conentration of NaCl for the production of chitinase from Bacillus sp. LJ-25 were 30℃, 6.5-7.0 and 1.0%, rspectively. Chitinolytic activity of Bacillus sp. LJ-25 was increased until the incubation of 168 hours, but after 168 hours, the activity was decreased.

17β-Estradiol의 심근 보호작용에 대한 연구 ; 재관류 부정맥을 유발한 동물실험

홍정석,김원,조규종,이미우,장성은,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: Although reperfusion certainly prevents tissue ischemia from possible cardiac death, several lines of evidence suggest that reperfusion may paradoxically aggravate the frequency of serious reperfusion-induced lethal arrhythmias. It has been reported that acute administration of estrogen at physiological concentrations reduced with myocardial ischemic injury in women with coronary heart disease. In studies with canines, acute administration by either the intra-muscular or the intra-coronary route similarly prevented ischemia and reperfusion dysrhythmias and also reduced the infarct size because the estrogen increased the distal coronary perfusion pressure, scavenged free radicals and had other effects during both ischemia and reperfusion. However, the canine heart is notoriously well collateralized. 17β-estradiol induces very little vasorelaxation in cat coronary rings, suggesting that increased ischemic myocardial blood flow dose not contribute to the protective effect. In the present study, employing a cat model of regional cardiac ischemia, we examined whether reperfusion rendered after acute administration of 17β-estradiol could lower the incidence of reperfusion-induced lethal arrhythmia and the death rate. Method: Adult mongrel male cats(n=31, 2.7∼4.5 kg) were anesthetized under positive-pressure artificial ventilation with room air. Electrocardiograms were recorded. The animals of the control group(n=15) were subjected to 20-minute left anterior descending coronary artery(LAD) occlusion followed by abrupt reperfusion. The animals in the experimental 17β-estradiol(2 or 20 ㎍/kg) group were subjected to ischemia/reperfusion insult following drug treatment: 17 β -estradiol was applied intravenously within the 60 seconds just before LAD ligation followed by abrupt reperfusion. The Fisher's exact test was used to compare the data from different animal groups(p<0.05). Results: The number of arrhythmias(ventricular premature beat, ventricular tachycardia and ventricular fibrillation) emerging during the reperfusion phase were not statistically different from that in the control group. The death rate in the 17β-estradiol 20㎍/kg group was lower from that in the control group(P value = 0.039). Conclusion: Acute administration of 17β -estradiol at a supraphysiological concentration might produce cardioprotective effects, not by modificating the coronary blood flow into the threatened myocardial region, but by other mechanisms that directly or indirectly increase the intrinsic myocardial ischemic tolerance in the cat during the reperfusion phase.