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이석종,이수정 대한의사협회 2018 대한의사협회지 Vol.61 No.11
The cutaneous melanoma has been regarded as rare disease entity in Korea for long time but it shows a silent growth recently. Furthermore the management of cutaneous melanoma including staging system, surgical principle, sentinel lymph node biopsy and subsequent complete node dissection and, most importantly, immunotherapy and target therapy against cutaneous melanoma recently. The incidence of cutaneous melanoma is steadily increasing in Korea but its increase is rapid recent 2 decades to 4.3 times and should be greater soon according to the steeper increase of life expectancy. New staging system proposed by American Joint Committee on Cancer (2017) includes changes in individual TNM category and stage groups, particularly from a prognostic viewpoint. Dermoscopy has been successfully introduced in the differential diagnosis of pigmented skin lesion focusing on cutaneous melanoma by non-invasive simple diagnostic tool. Sentinel lymph node biopsy was a issue of long debate whether survival benefit is real or not. Temporary conclusion about this question is reached after two large scale studies and immediate complete node dissection should be performed in a certain situations. Most important change is drug therapy focusing on immunotherapy and target therapy. Braf- and MEK-inhibitor, immune checkpoint inhibitor and PD-1 blocker has been proved to be effective as a sole or combination regimen against advanced and/or high-risk adjuvant setting of cutaneous melanoma. In conclusion, these remarkable changes will be reviewed shortly here.
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Intuitionistic Fuzzy θ-compact spaces
이석종,엄연석 한국지능시스템학회 2011 한국지능시스템학회 학술발표 논문집 Vol.21 No.1
In this paper, we introduce and study notion of intuitionistic fuzzy θ-compact space.
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풍하중을 받는 일부 개방형 건축물의 측면 개구부 변화에 따른 실내압 평가
이석종,하영철 한국풍공학회 2002 한국풍공학회지 Vol.6 No.2
본 연구는 풍하중을 받는 일부 개방형 건축물의 실내압 변화 특성을 풍동실험과 이론해석을 통하여 평가하는 것이 목적이며, 평가 시에는 개구부의 위치 및 크기 변화를 중점 고려사항으로 하였다. 실험모형은 측벽면 및 후면의 개구크기를 0.2%와 3.5% 및 개구부위치를 변화시켰을 경우의 모형을 9개종류로 하여 실내압의 변화특성을 이론해석과 풍동실험을 실시하여 비교 분석을 하였다. 실험결과로부터 일부 개방형 건축물의 경우 바람으로 발생하는 이론해석식에 의하여 큰 오차 없이 평가 할 수 있음을 나타냈다. 또한, NBCC규준의 실내압계수와 풍하중을 받는 일부 개방형 건축물의 실내압계수를 비교하여 나타내었다 Wind-induced internal pressures in partially opened buildings were evaluated by using both a wind tunnel test and an analytical method. The change of the location and size of the wall openings was considered in the evaluation. The area of the openings was variable between 0.2 % and 3.5 % of the wall area, and the location of the openings was changed into 9 types. The experimental results have been compared with analytical evaluation to investigate the accuracy of a simple analytical approach for the evaluation of wind-induced internal pressures in buildings. Analytically evaluated internal pressure coefficients show a good agreement with experimental results determined by wind tunnel tests. The Comparison of internal pressure coefficients with those stipulated in the NBCC Standard indicates that NBCC Standard seems to underestimate wind-induced internal pressures for partially opened buildings.
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Fuzzy r-regular open sets and fuzzy almost r-continuous maps
이석종,이은표 대한수학회 2002 대한수학회보 Vol.39 No.3
We introduce the concepts of fuzzy r-regular open setsand fuzzy almost r-continuous maps in the fuzzy topology ofChattopadhyay. Also we investigate the equivalent conditions ofthe fuzzy almost r-continuity.
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