Material Balance and Metabolic Flux Analysis for Styrene Epoxidation Reaction by a styC Knockout Mutant of Pseudomonas Putida SN1

Jong_Wan Bae,Seung-Hyuk Kim,Sun-Gu Lee,Sunghoon Park 한국생물공학회 2005 한국생물공학회 학술대회 Vol.2005 No.4

신호인자와 목표치가 디지털 변수인 경우를 고려한 동적 파라미터 설계 적용(2)

송종대,황규완,배홍석 慶南專門大學 2000 論文集 Vol.28 No.1

초등학교 어린이의 선수 활동을 통한 사회성 변화 연구

이완섭,배종진,강진구 춘천교육대학교 초등교육연구소 2003 敎育硏究 Vol.20 No.-

선형전동기의 고속도 위치결정제어에 관한 연구

이동철,배종일,김중완 釜山工業大學校 1991 論文集 Vol.33 No.-

This is a study on a high speed and high accuracy position determination control about Linear DC Motor (LDM) as a controlled system. In this research, a linear encoder using magnetic resistive effect element is used as the dual mode position determination control method consisting of speed and analog controls. The speed contol is realized on a linear switching line according to Bang-bang control in the shortest time. By the proposed method, existence condition and robustness of sliding mode are also studied. An analog position control is constructed from linear feedback control system and LDM is stopped and kept at the origin. Finally through experiments the effectiveness of the above method is certified.

무손실 공진기를 이용한 병렬형 능동전력필터의 Digital 제어

박지호,김동완,배종일,우정인 동아대학교 정보기술연구소 2000 情報通信硏究所論文誌 Vol.8 No.1

In this paper, a new simple control method for active power filter which can realized the complete compensation of the harmonic currents is proposed. In the proposed scheme, a compensating current reference generator employing lossless resonator implemented by a DSP(Digital Signal Processor) is introduced. Deadbeat control is employed to control the active power filter. The switching pulse width based SVM(Space Vector Modulation) is adopted so that the current of active power filter is been exactly equal to its reference at the next sampling instant. To compensate the computation delay of digital controller, the prediction of current is achieved by the current observer with deadbeat response.

인슐린 비의존형 당뇨병 환자에서 24시간 혈압 변동 및 요중 알부민 배설량에 관한 연구

주기산,안기완,정종훈,배학연,홍순표 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Recently, blood pressure(BP) starts to increase in close relationship to development of persistent microalbuminuria in diabetes. Thus, author studied 24-hour BP changes in diabetics compared to the those in nondiabetics and the changes of urinary albumin excretion (UAE) according to 24-hour BP changes in diabetics with microalbuminuria. Twenty-four-hour ambulatory blood pressure monitoring(ABPPM) was performed in 38 NIDDM patients(18 normotensives and 20 hypertensives) and in 37 control subjects without diabetes(18 normotensives and 19 hypertensives) . Also 24-hour ABPM was performed in 38 diabetics (20 microalbuminurit and 18 normoalbuminuric). The analysis of individual recordings allowed us to detect an impaired circadian pattern(the disappearance of the nocturnal BP decrease or a paradoxical BP increase) in 30% of the normotensive and 31% of the hypertensive diabetics. Twenty-four-hour ABPM(night systolic/diastolic ±SD mmHg) was significantly higher in microabluminuric(124.2 ±11.4/75.1±8.2 mmHg) than in normoalbuminuric subject, (114.0±7.6/64.6±6.6 mmHg, p<0.05). This study suggests that not only awaking BP but also especially day-night minimum SBP decrease are highly responsible for the renal impairment in NIDDM patients, unrelation to hypertension. Thus. ABPM reflects the association between UAE and blood pressure in diabetics more precisely than clinical measurements. and a significant correlation exists between rate of increase in Urinary albumin excretion and blood pressure in diabetics.

인공관절 치환술 후 발생한 대퇴 골절 치료에서 금속판 내고정의 문제점

박명식,최병완,배현경,박종혁 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목 적: 최근 빈도가 증가하고 골절양상도 복잡해지는 인공관절 수술 후 발생한 대퇴 골절의 발생 빈도와 금속판을 이용한 치료 시의 문제점을 문헌 고찰과 함께 보고하고자 한다. 대상 및 방법: 1985년부터 1998년까지 시행된 1,275 (1,188 일차 치환, 97 재치환술)례의 고관절 치환술 시행 환자 중 52명에서 발생한 52ㄹㅖ의 대퇴부 골절을 대상으로 조사하였다. 이를 안정성 여부와 스템 끝 주위의 골절 위치에 따라서 근위부 (Ⅰ), 중심부 (스템 주위) (Ⅱ), 언위부(Ⅲ)로 구분하였고 이를 다시 비전위성 (A), 전위성 (B), 불안정성 삽입물 (C)으로 세부나였다. 치료의 방법으로 삽입물이 안정성을 가진 근위부 골절 (제 1형)에서는 부목 고정이나 환상 강선 고정을 시행하였으며, 스템 끝 (제 2형)이나 원위부 (제 3형) 골절에서는 금속판과 나사못 등을 사용하고 대퇴골 과상부인 슬관절 주변의 골절인 경우 외고정 장치 장착을 하였다. 금속판 고정을 한 경우는 골이식술을 시도하였다. 결 과: 인공관절 치환 후 발생한 골절의 빈도는 4.1%이었고, 이 중 술 중 골절은 1.5%, 술 후 골절은 2.6%이었다. 골절의 평균 유합기간은 3.1개월이었다. 금속판을 이용하여 치료한 경우 2례의 불유합과 3례의 재골절 중 1례는 골절 유합 후 보행 도중 낙상에 의하여, 1례는 골절부 유합 후 금속판 제거 후 발생하였으며, 1례는 체중 부하 도중 발생한 골절이었다. 제 Ⅲ형 골절의 경우 전례에서 스템의 이완 소견은 볼 수 없었다. 결 론: 저자들은 인공고관절 치환술 후 발생한 대퇴골 골절 치료에서 금속판 내고정 후 5례의 비교적 많은 합병증을 경험하였다. 이 중 2례는 부적절한 짧은 금속판의 선택과 조기 보행, 나머지 3례는 금속판 및 나사못과 관련된 골절로서 스트레스가 집중되는 부위인 대퇴 스템 원위단이나 금속판의 근위부는 재골절의 위험이 있으므로 골절의 치료에 있어서 골이식이나 긴 금속판 사용, 골유합시까지 외부충격에 보호 등으로 재골절의 위험 빈도를 해결해야 한다. Purpose: The purpose was to evaluate the postoperative periprosthetic femur fracture of hip arthroplasty and relative problems of management using plate fixation. Material and Method: We reviewed 37 cases of femoral fractures out of 1,270 (1,183 primary hips and 97 revision hips) hips which received hip arthroplasty during the observation period(1985~1998). We classified them according to the stability and the location of the fractures related to the stem tip: Proximal (Ⅰ), middle (around stem)(Ⅱ) and distal(Ⅲ). Then we subclassified the fractures as cortical perforation or a fissure, undisplaced (A), displaced(B) and unstable prosthesis (C). we managed periprosthetic fracture with splint applied or cerclage proximal fracture (type Ⅰ), plate fixation and bone grafts in the step tip(type Ⅱ) or distal fracture (type Ⅲ). Un unstable fractures, we revised them with long fluted stems. Result: The average union time is 3.1 months (range, 2~6.2 months). After management of fracture with plate showed 5 complications, two nonunion and three refractures. The causes of nonunion are weight bearing and a too short plate. The causes of refracture are screw fixation and empty hole just distal to stem tip. The other caused by the roles of stress riser in proximal screw of blade plate in management of supracondylar fracture. Conclusion: We recommend the use of cerclage band system of fixed in a more proximal site in long plate and bone graft. In unstable prosthesis, we had taken a best results after revised with distal fluted stem, in which we don't need further distal stability like a additional cerclage or locking screw and additional bone graft.

주의력결핍 과잉행동장애 아동의 지적수준에 따른 정신병리와 실행기능의 차이

천은진,서완석,이종범,김진성,구본훈,송창진,성형모,배준용,배대석 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.4

To investigate psychopathoIogy and executive functions of attention deficit hyperactivity disorder (ADHD) children according to intelligence level, this study included 197 ADHD children who visited the outpatient department of neuropsychiatry of YeungNam University Medical Center, from July 2000 to June 2002. The children were divided into groups based on their intelligence levels. They were compared by the Personality Inventory for Children (PIC), Conncers' Continuous Performence Test (CPT), and Wisconsin Card Sorting Test (WCST). There were significant differences in PIC, on the subscales of verbal development, socialization and autism. In the CPT, there was no significant difference. In the WCST, there were significant differences in the total number of errors, the number of perseverative errors, the number of completed categories and the number of trials needed to complete the first category. Considering these results, the intelligence level of ADHD children is related to their disabilities and behavioral symptoms.Executive functions such as abstract thinking, categorization, working memory and flexibility had significant relationship to the intelligence levels of ADHD children. Therefore, the intelligence level of children with ADHD influences the higher executive functions of regulating attention and information processing rather than attentional functions and capacity alone.

급성 심근경색증을 동반한 혈전성 혈소판 감소성 자반증 1예

이태희,김진혁,김완중,박지영,강흥선,조정휘,김권삼,송정상,배종화 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

Construction and Characterization of a Recombinant Whole-cell Biocatalyst of Escherichia coli Expressing Styrene Monooxygenase under the Control of Arabinose Promoter

Jong Wan Bae,이선구,정용주,Seunghee Shin,S. Mohan Raj,Song Eun Lee,박성훈 한국생물공학회 2008 Biotechnology and Bioprocess Engineering Vol.13 No.1

A recombinant Escherichia coli (pBAB1) containing styrene monooxygenase (SMO) was developed for the conversion of styrene to enantiopure (S)-styrene oxide that is an important chiral building block in organic synthesis. The styAB genes encoding SMO was cloned into a multicopy plasmid under the tightly regulated promoter of bacterial L-arabinose operon which is inducible by L-arabinose. The recombinant showed that expression level of StyA protein and whole-cell SMO activities were varied depending on the concentration of the inducer L-arabinose. The maximum SMO activity was 108 U/g cdw when the cells were induced with 0.2% L-arabinose. SDS-PAGE and Western blot analyses indicated that whole-cell SMO activity was strongly correlated with the expression level of StyA protein. Organic-aqueous two-phase experiment could yield 50 mM enantiopure (S)-styrene oxide in organic phase in 18 h, but the recombinant SMO activity was unstable during the reaction. The expression of styAB under the control of L-arabinose promoter was significantly repressed in the presence of glucose.