기종성 신우신염 1례

이재욱,구정태,서정일,양창헌,이정호,이동철,이영현,이활,이경섭 동국대학교 경주대학 1997 東國論集 Vol.16 No.1

기종성 신우신염은 주로 당뇨병환자나 폐쇄성 요로질환을 가진 환자에 발생하며 특징적으로 신실질 및 그 주위조직에 가스를 형성하면서 심한 조직괴사를 일으키는 매우 드문 급성 화농성 신감염으로 사망률이 높은 질환이다. 이 질환은 1989년 Kelly와 MacCallum에 의해 처음 보고된 이래 외국문헌에 약 90례 정도가 보고되어 있으며 국내에는 28례가 보고되어 있다. 수액 및 전해질 보충, 인슐린 투여를 통한 적절한 혈당조절 및 항생제 투여등의 내과적 치료와 절개배농 및 신적출술등의 수술적 치료 방법이 있다. 내과적 치료로 가스의 감소가 없는 경우에는 즉각적인 수술적 치료를 시행하여야하므로 이 가스변화에 대한 추적관찰이 중요하다 하겠다. 본 저자들은 당뇨병환자에서 발생한 기종성 신우신염 1례를 내과적 요법을 치험하였기에 문헌고찰과 함께 보고하고자 한다. Emphysematous pyelonephritis is rare, life-threatening infection of the renal parenchyma and perirenal tisseue. This disease is characterized by the production of intrarenal and perirenal gas and is frequently encountered in patients with diabetes mellitus or urinary obstruction. We experienced a case of emphysematouse pyelonephritis in a 62 years old women with poorly controlled diabetes mellitus who had been managed with medical theraphy. So we report this case with a review of the referenced literatures.

고빌리루빈혈증을 동반한 자가면역성 간염 1례

서영범,김성욱,장재식,강혁주,이중현,윤병구,김욱년,이광헌,이구,유석동,양창헌,이정호,이영현,이창우,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

자가면역성 간염은 대개 만성 경과를 가지며, 혈중 자가면역항체와 혈청 글로불린치의 상승, 그리고 조직학적으로 괴사 염증성 변화를 특징으로 하는 질환으로 아직 정확한 병인이 밝혀져 있지 않은 상태이다. 발병연령은 대개 젊은 영자(15-25세)에서 호발한다. 이 질환은 급성 간염의 임상경과를 보일 수 있으나, 심한 급성 간염이나 전격성 간염으로도 나타날 수 있는데, 이 경우 아주 나쁜 예후를 보인다고 한다. 치료는 자가면역성 간염 임상 경과의 다양성이나 병인, 병리기전의 불확실성에도 불구하고 대개 steroid 치료에 반응하는 것으로 알려져 있으며 대개 80%의 관해율을 나타내며 궁극적으로 간경변으로의 진행을 막을 수 있는 것으로 보인다. 저자들은 58세 남자에서 발생한 급성의 경과를 가지고 심한 황달을 동반한 자가면역성 간염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and a high serum globulin level. The age of onset of AIH show a peak between the age of 15 and 25 years. AIH can develop and be manifested as acute hepatitis, but severe form of acute hepatitis or fulminant hepatic failure has a poor prognosis. Although AIH is likely to progress from chronic active hepatitis to cirrhosis, steroid therapy can control the disease activity, prolong survival, improve the quality of life , and defer liver transplantation. In the present report we describe a 58-year-old man who admitted because of progressive jaundice and fatigue. He was diagnosed with AIH from laboratory test result showing positivity for antinuclear antibodies, anti-smooth muscle antibodies, and negativity for hepatitis viral markers and from liver biopsy. Steroid therapy, oral administration of prednisolone, was effective in improving the liver function test. Following liver biopsy 6 months after onset shows markedly improved necroinflammatory activity.

국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

A. 高校 科學 (生物·地球科學) 및 數學科 探究學習의 評價模型 定立과 評價紙 開發

李相協,權炳奎,林在圭,孫文求,吳岱燮,楊洪準,梁承榮,姜用熙,林成圭,金正遠,金吉民,兪正在 경북대학교 과학교육연구소 1982 科學敎育硏究誌 Vol.6 No.-

Currently the evaluation of high school science and mathematics learning has been too much knowledge-centered without concerning the inquiring ability or scientific attitude. This study, therefore, was made for the purpose of establishing of evaluation model for high school science (biology and earth science) and mathematics learning and its evaluation items. In this paper, the research was done about three fields, biology, earth science and mathematics. 1. For the biology, the evaluation methods of inquiry learning were studied with the foreign references, and proper evaluation items were suggested. 2. For the earth science, after analizing 5 kinds of earth science textbook of current using in high school, essential 19 items were selected. 5 of them were tested in test group and control group, then, the results were analized. 3. For the mathematice, the teaching elements of「Set」and「Flow chart」in mathematics (Ⅰ) were selected and structured. Detailed teaching objects were established and evaluation items were introduced.

다층박막 WC-Cr_(1-x)Al_(x)N의 Al 함량에 따른 부식특성에 관한 연구

이정호,안승호,김정구 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.11

Multilayered WC-Cr_(1-x)Al_(x)N coatings were deposited on AISI D2 steel by cathodic arc ion plating process (CAIP). The Al concentration was controlled by using evaporation source for Al and fixing the evaporation rate of the other metals (WC alloy and Cr). Five types of WC-Cr_(1-x)Al_(x)N were deposited, i.e., WC-Cr_(0.6)Al_(0.4)N, WC-Cr_(0.57)Al_(0.43)N, WC-Cr_(0.53)Al_(0.47)N, WC-Cr_(0.48)Al_(0.52)N, and WC-Cr_(0.45)Al_(0.55)N. The corrosion behavior in deaerated 3.5 wt.% NaCl solution for the prepared samples was investigated by electrochemical tests (potentiodynamic polarization test, galvanic corrosion test, electrochemical impedance spectroscopy (EIS)) and surface analyses (scanning electron microscopy (SEM), X-ray diffractometry (XRD), glow discharge optical emission spectroscopy (GDOES), and electron probe micro analyzer (EPMA)). The results from potentiodynamic polarization test showed that the WC-Cr_(0.48)Al_(0.52)N coating with the lower porosity (0.144) enhanced the corrosion resistance. Galvanic corrosion test was accomplished using the galvanic couple between the substrate and the WC-Cr_(1-x)Al_(x)N coating. The WC-Cr_(0.6)Al_(0.4)N showed a higher galvanic current density. In EIS measurements, the WC-Cr_(0.48)Al_(0.52)N coating showed an increased charge transfer resistance (R_(ct)). The measured electrochemical tests indicated that the WC-Cr_(0.48)Al_(0.52)N coating with the lower corrosion current density (3.023 μA/㎠) and higher charge transfer resistance (158.7 kΩ㎠) enhanced corrosion resistance.

스포츠 스쿠버 다이버의 심해 다이빙 기술 분석

이장구,구정철,신철호 한국학교체육학회 2002 한국학교 체육학회지 Vol.12 No.2

본 연구는 스포츠 스쿠버 다이버가 안전수칙을 준수하며 심해다이빙을 안전하게 하고 있는지 그 실태를 분석하는데 있다. 연구 목적을 달성하기 위하여, 다이버 9명의 다이빙 컴퓨터를 회수한 후, SUUNTO dive log 프로그램과 다이빙 기록 분석도구를 이용해서 자료를 수집하였다. 다이빙 사례 37회를 첫 잠수와 재 잠수로 비교 분석하였으며, 분석 결과 다음과 같은 결론을 얻었다. 첫째, 다이버의 다이빙 한계 수심 초과 빈도는 첫 잠수 시 5회(13.5%)로 나타났다. 둘째, 다이버는 분당 9m이하의 상승속도를 준수하였다. 셋째, 다이버의 안전 감압 미실시 빈도는 첫 잠수 시 16회(43%), 재 잠수 시 10회(27%)로 나타났다. 넷째, 다이버는 재 잠수 시 전체 다이빙 시간을 2.7분 더 소요하는 것으로 나타났다. 다섯째, 다이버는 무감압 한계 시간 내에서 안전하게 다이빙을 하고 있었다. The purpose of this study was to analysis the deep diving actual condition of safety rule of to observe sport SCUBA divers. An analysis first dive and repeated 37 cycle, use SUUNTO dive log program and dive log analysis tools, the right of restitution of diving computer of 9 diver's. The study has achived the following findings. First, the number of times of times of depth limit to exceed, showed 5(13.5%) at the first dive. Second, all divers observed the velocity of ascent per minute under 9m. Third, the divers' failure number of times of observing the safety decompression stop showed 16(43%) at the first dive and 10(27%) at the repeated dive. Fourth, divers' average total dive time was 27.6minutes at the first dive and 30.3 minutes at the repeated dive. Fifth, they dived safely within the no-decompression limit.

팔영산 삼림식생과 토양환경

이호준,김종홍,배병호,박문수,전영문,강재구,신정식 建國大學校基礎科學硏究所 1997 理學論集 Vol.22 No.-

전라남도 고흥군 소재 팔영산 (608.6 m) 일대의 삼림군락에 대한 색생조사를 1993년 10월부터 1995년 7월까지 실시하였다. 조사한 자료는 Z-M 방식에 의해 종조성표를 작성하였다. 이에 따라 삼림군락은 신갈나무군락, 졸참나무군락, 굴참나무군락, 서어나무군락, 소나무군락등 5 개 군락으로 분류되었다. 입지와 환경과의 유기적 관계를 조사하기 위해 토양을 분석한 결과, 신갈나무군락은 토양의 비옥도가 높은 산의 능선 부위에 집중 분포하였으며, 굴참나무군락과 소나무군락은 토양의 비옥도가 낮고 비교적 건조한 고도 400 m 이하 지역에 주로 군락을 형성하고 있었다. 또한 졸참나무군락은 고도 300 - 550 m 이내에서 부분적으로 나타났으며, 서어나무군락은 토양의 비옥도가 양호한 고도 300 - 550 m 사이의 골짜기 주변에 국지적으로 분포하였다. 팔영산 삼림식생의 특징은 상록활엽수림이 형성될 수 있는 지역이나 후박나무, 동백나무, 사스레피나무 등의 몇몇 종을 제외하고는 상록활엽수의 분포를 확인할 수 없었으며, 일부 식재림을 제외한 대부분의 지역이 낙엽활엽수와 소나무의 혼효림으로 구성되어 있었다. The phytosociological study forest vegetation on Mt. Palyoung (608.6 m) was investigated from October 1993 to July 1995 in Koheug-Gun, Cheonnam province. According to Z-M method, the floristic composition table of the forest vegetation was divided into five community as follows; Quercus mongolica community, Quercus serrata community, Quercus variabilis community, Pinus densiflora community, Carpinus laxiflora community. The soil was analyzed to investigated the soil conditions and soil fertility. As a result, the organic matters which showing soil fertility were found to be low Quercus variabilis and Pinus densiflora community at comparatively xerophic conditions, below 400 m altitude, while they were increased in Quercus mongolica community on mountain ridge, and that Quercus serrata community was appeared 300-550 m altitude around mountain stream to moderate soilfertility. The forest vegetation of Mt. Palyoung area unconfirmed capable of evergreen broad-leaved forest, but appeared to Machilus thunbergii, Camellia japonica and Eurya japonica species etc. On the other hand, surveyed site's vegetation was distributed mixed forest of deciduous leaved forest and Pinus desiflora, except for some afforestation.

바둑판을 이용한 흑백 게임의 최적해를 구하는 선형대수학 알고리즘

이상구,박종빈,양정모,김익표 한국수학교육학회 2004 수학교육 Vol.43 No.1

For finding the optimal strategy in Blackout game which was introduced in the homepage of popular movie "Beautiful mind", we develop a mathematical proof and an algorithm with a software. We only use the concept of basis and knowledge of basic linear algebra. This process can be extended to the fullsize Go table problem and shows why we have to study mathematics at the college level.

상악골절단술 후 외전신경마비를 동반한 경동맥 해면정맥돌루

이원학,김동률,홍광진,이정구 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

Carotid cavernous sinus fistula(CCSF) is an abnormal communication at the base of the skull between the internal carotid artery and the cavernous sinus. Fistula is almost associated with extensive facial trauma as a result of direct or indirect forces. Most fistulas of traumatic origin develop as a result of fractures through the base of the skull, which cause the laceration of the internal carotid artery near the cavernous sinus. The signs and symptoms of CCSF are pulsating exophthalmosis, orbital headache, pain, orbital or frontal bruit, loss of visual acuity, diplopia and ophthalmoplegia. Angiography reveals a definite CCSF and a detachable balloon embolization is known to be the treatment of choice. Even though carotid cavernous sinus fistula is an uncommon complication after orthognathic surgery, several cases of CCSF due to congenital anomalies, pre-existing aneurysms and abnormally thickened maxillary posterior wall have been reported in the literature. We have experienced a case of CCSF after Le Fort I osteotomy for maxillary advancement in skeletal class III patient and the cause, pathogenesis, diagnosis and treatment of this case.

골화석증 1례 보고

오정환,이문구 건국대학교 의과학연구소 1994 건국의과학학술지 Vol.4 No.-

Osteopetrosis, also known as Albers-Schonberg disease, marble bone, osteosclerosis fragilis, or chalk bone, is a rare hereditary, congenital and familial disease, characterized by a marked increase in the radiodensity of the bone and by an abnormality in the shape of the long bone, especially the metaphysis. It may occur in autosomal recessive form with severe, generalized bone changes in the new born infant that result in early death or in a more benign autosomal dominant form with less extensive bone involvement and relatively good prognosis. We experienced a case of a benign autosomal dominant form of osteopetrosis incidentally and reporting this case with a review of the literatures.