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이대희,조헌노,원세열,이영민 인제대학교 1999 仁濟論叢 Vol.14 No.3
본 연구에서는 변압기 냉각용 각-관(Shell and Tube) 열교환기의 성능을 실험적으로 테스트하여 열교환기의 냉각능력을 향상시키는 기술을 개발하고자 하였다. 예열수조 2개를 항온조와 함께 사용함으로써 열교환기 입구에서와 온수의 초기온도를 60℃로 유지하고, cooling tower를 이용하여 입구에서 냉각수 온도를 20℃로 유지하였다. 냉각수 유량변화(5ℓ/min, 10ℓ/min, 15ℓ/min)에 따른 baffle의 형태(Single-segmental baffle, Double-segmental baffle, Disk & Doughnut baffle, Helical baffle)와 baffle의 개수(7개에서 5개) 및 tube의 개수(26개에서 18개)를 변화시켰을 때 열교환기의 냉각능력을 각각 실험하였다. 온수와 냉각수의 입ㆍ출구에서의 온도변화를 측정하기 위하여 Thermocouple을 온수와 냉각수 관의 입ㆍ출구에 하나씩 설치하였다. 실험결과 Disk & Doughnut, Helical baffle, Double-segmental baffle의 열전달률이 Single-segmental baffle보다 5.3%, 5.5%, 11.8% 높고, Double-segmental baffle의 경우 Tube 수의 감소율이 35%일 때 열전달률의 감소율은 14.3%임을 알 수 있었고, baffle의 수가 5개에서 7개로 증가했을 때 열전달률이 12.1% 증가함을 알았다. An experimental study to enhance the cooling capacity of the shell and tube type heat exchanger has been carried out. The initial temperature of hot water in the heat exchanger is maintained at 60℃, using two preheating water baths and one constant temperature water bath, while the coolant temperature is maintained at 20℃ by way of the cooling tower. For the coolant rates of 5 ℓ/min, 10 ℓ/min, 15 ℓ/min, the experiments to determine the heat exchanger cooling capacity have been performed using the various types of baffle(Single- segmental baffle, Double-segmental baffle, Disk & Doughnut baffle, Helical baffle), the number of baffles(from 7 to 5) and number of tubes(from 26 to 18). Thermocouples are installed in the inlet and outlet of hot-water and coolant tube to measure the temperature difference. It was found that the heat transfer rates for Disk & Doughnut baffle, Helical baffle, Double-segmental baffle are 5.3%, 5.5%, 11.8% higher than the Single-segmental baffle, respectively. When the number of tube is reduce by 35%, the 14.3% decrease in the heat transfer rate occurs, while when the number of baffle increases from 5 to 7, the 12% increase in the heat transfer rate occurs.
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Young Min Choi,Sang Hoon Lee,Jee Hwan Choe,Kyoung Heon Kim,Min Suk Rhee,Byoung Chul Kim 한국축산식품학회 2013 한국축산식품학회지 Vol.33 No.5
The objective of this study was to investigate the effects of supercritical carbon dioxide (SC-CO2) treatment on meat quality and sensory evaluation of marinated pork. Meat marinated in two traditional Korean marinades, soy sauce and hot-pepper paste, and raw marinated meat were then treated with 7.4, 12.2, or 15.2 MPa CO2 at 31.1oC for 10 min. The SC-CO2 treatments had no effect on the meat pH (p>0.05) or Warner-Bratzler shear force (p>0.05). There was no significant difference (p>0.05) in the total loss (sum of treatment loss and cooking loss) between the control and SC-CO2 treated samples at 15.2 MPa (soy sauce marinated pork: 21.78 vs. 18.97%; hot-pepper marinated pork: 21.61 vs. 18.01%). After the SC-CO2 treatment, lighter surface colors were observed in the treatment samples compared to those of the control samples (p< 0.001). However, tasting panelists were unable to distinguish a difference in color or in overall acceptability of the control and treatment (p>0.05). In the case of soy sauce marinated pork, when SC-CO2 applied at 15.2 MPa and 31.1oC for 10 min, treatment samples showed a tenderer meat than the control samples. Therefore, the SC-CO2 treatment conditions had no adverse effects on the sensory quality characteristics of the marinated meat products.
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Choi, Young Min,Lee, Sang Hoon,Choe, Jee Hwan,Kim, Kyoung Heon,Rhee, Min Suk,Kim, Byoung Chul Korean Society for Food Science of Animal Resource 2013 한국축산식품학회지 Vol.33 No.5
The objective of this study was to investigate the effects of supercritical carbon dioxide (SC-$CO_2$) treatment on meat quality and sensory evaluation of marinated pork. Meat marinated in two traditional Korean marinades, soy sauce and hot-pepper paste, and raw marinated meat were then treated with 7.4, 12.2, or 15.2 MPa $CO_2$ at $31.1^{\circ}C$for 10 min. The SC-$CO_2$ treatments had no effect on the meat pH (p>0.05) or Warner-Bratzler shear force (p>0.05). There was no significant difference (p>0.05) in the total loss (sum of treatment loss and cooking loss) between the control and SC-$CO_2$ treated samples at 15.2 MPa (soy sauce marinated pork: 21.78 vs. 18.97%; hot-pepper marinated pork: 21.61 vs. 18.01%). After the SC-$CO_2$ treatment, lighter surface colors were observed in the treatment samples compared to those of the control samples (p< 0.001). However, tasting panelists were unable to distinguish a difference in color or in overall acceptability of the control and treatment (p>0.05). In the case of soy sauce marinated pork, when SC-$CO_2$ applied at 15.2 MPa and $31.1^{\circ}C$for 10 min, treatment samples showed a tenderer meat than the control samples. Therefore, the SC-$CO_2$ treatment conditions had no adverse effects on the sensory quality characteristics of the marinated meat products.
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이화민,정순영,유헌창 한국컴퓨터교육학회 2002 컴퓨터교육학회 논문지 Vol.5 No.2
본 논문에서는 기존의 분산 컴퓨팅 시스템의 결합 포용 기법에 멀티 에이전트의 개념을 도입하여 운영체제에 독립적인 에이전트틀 이용한 회복기법을 제안한다. 기존의 복귀회복기법들은 운영체제의 관리하에서 결함 발생 시 회복에 관련된 동기화를 수행하는데, 이는 전체 분산 컴퓨팅 시스템의 성능을 저하시키는 원인이 되었다. 이러한 문제점을 해결하기 위해 본 논문에서는 프로세스의 회복을 담당할 회복 에이전트, 결함 포용 규칙과 정보를 유지 · 관리하는 정보 에이전트, 전체 에이전트간의 통신 기능을 담당할 조정 에이전트를 정의 및 설계하고 회복 에이전트를 이용한 회복 알고리즘을 제안한다. 그리고 코바 환경에서 자바와 에이전트 통신 언어를 이용하여 제안한 회복 알고리즘을 실험하였다. 분산 컴퓨팅 시스템에서 회복 에이전트의 도입은 결함 발생 프로세스의 결합 회복 작업을 어플리케이션 계층과 독립적인 별도의 계층으로 계층화하여 결함 포용을 위한 메카니즘의 이식성증대 및 확장성 증대를 가져온다. This paper proposes a new approach to rollback-recovery using multi-agent in distributed computing system. Previous rollback-recovery protocols are dependent on inherent communication and operating system, which causes a decline of computing performance in distributed computing system. By using multi-agent, we propose rollback-recovery protocol that is independent on operating system. We define three kinds of agent. One is a recovery agent that performs rollback-recovery protocol after a failure. Other is an information agent that constructs domain knowledge as a rule of fault tolerance and information during failure-free operation. The other is facilitator agent that controls the efficient communication between agents. Also we propose rollback-recovery protocol using multi-agent and simulated the proposed rollback-recovery protocol using JAVA and agent communication language in CORBA environment.
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장기간 Risperidone 투여후 지연성으로 발생한 Neuroleptic Malignant Syndrome 1례
이헌정,조방현,김인,이민수 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.4
Risperidone은 비교적 최근에 개발된 항정신병약물이며, 그것이 가진 도파민 D2 수용체와 세로토닌2 수용체를 차단하는 작용기전, 추체외로 부작용과 지연성 운동장애가 적다는 점, 정신분열병의 음성증상에도 효과가 있다는 점에서 흔히 비전형적 약물로 불리운다. 그러나 이러한 비전형성에도 불구하고, 이미 전세계적으로는 15개 정도의 risperidone에 의한 신경이완제 악성증후군(neuroleptic malignant syndrome : NMS)의 보고가 있으며. 국내에서도 최근 하나의 증례가 보고되었다. 저자들은 정신분열병으로 장기간 risperidone으로 치료받던 젊은 남자 환자에서 치료 1년 9개월만에 발생된 NMS 1례를 경험하였기에 관련문헌의 고찰과 더불어 증례보고하고자 한다. Risperidone is a relatively new antipsychotic agent. It is often referred to as 'atypical', because it has a mechanism of action that blocks post synaptic dopamine-2 and serotonin-2 receptors, it is associated with fewer extrapyramidal side effects, it is not yet associated with tardive dyskinesia, and it may have some efficacy on negative symptoms of schizophrenia. In despite of its 'atypical' nature, there are already more than 15 reports of risperidone-induced neuroleptic malignant syndrome. Only one case of risperidone-induced NMS was reported recently in Korea. We report one case of delayed risperidone-induced neuroleptic malignant syndrome in young male patient and review the related articles.
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이헌정,최낙경,김린,이민수,김용구 대한신경정신의학회 2000 신경정신의학 Vol.39 No.6
연구목적 : 낮은 혈청 콜레스트롤 농도와 자살과 같은 폭력적 행동에 관한 관련성에 관한 논란이 있어왔다. 본 연구는 자살 시도 후 응급실로 내원한 환자에서 혈청 총 콜레스테롤 농도만이 아닌 전반적인 혈청 지질 농도의 저하 여부를 조사하였으며, 자살 시도 상황을 평가하는 객관적 척도를 통하여 자살 시도 상황에서 자살 시도의 심각도와 혈청 지질 농도의 관계에 대하여 연구하였다. 방 법 : 1998년 7월부터 1999년 6월 사이에 자살 시도후 고려대학교 의료원 응급실로 내원한 50명의 자살 시도자를 연구대상으로 하였다. 이들은 정신과 의사의 면담을 통하여 정신과적 진단을 받았으며 동시에 위험-구조척도(RRR). HDRS, BPRS 등이 평가되었다. 또한 동 기간에 본원 정신과에서 입원 치료를 받은 자살 시도가 없었던 환자중, 대상군과 나이, 성별, 진단을 맞추어서 50명의 환자를 선정하여 정신과 환자 대조군으로 하였다. 자살 시도군과 대조군의 혈청 지질농도가 t-test를 통하여 비교되었으며, RRR점수와 혈청 지질 농도, HDRS,BPRS와의 사이의 연관성 Spearman순위 상관계수로 분석되었다. 결 과 : 자살 시도자중 주요우울증이 29명, 정신분열병이 2명, 인격장애가 19명이었으며, 자살 시도군의 혈청 총 콜레스트롤 농도(t=---3.29, p=.001). 총 지질 농도(t=-2.62, p=.01), LDL농도(t=-2.64, p=.011)가 대조군보다 유의하게 낮았다. 진단별로는 주요우울증에서는 총 콜레스트롤 농도, 총 지질 농도, LDL 농도가 대조군에 비하여 낮았으나, 인격장애에서는 혈청 콜레스트롤 농돤이 대조군보다 낮았다. 자살 시도군에서 RRR 점수는 혈청 콜레스테롤 농도와 부적 상관관계를 보였으나 (γ=.-293,p=.039), BPRS(γ=.544, p<.001)와 HDRS(γ=.488, p=.001)와는 정적 상관관계를 보였다. 결 론 : 자살 시도군에서 혈청 지질 농도 중 총 콜레스테롤, 총 지질, LDL농도가 유의하게 저하되어있음을 확인하였다. 또한 자살의 심각도를 평가한 RRR 정수가 혈청 총 콜레스테롤 농도와 유의하게 상관성이 있음이 확인되었다. 이는 낮은 혈청 총 콜레스테롤 농도가 심각한 자살 시도와 연관이 있음을 보여주는 것이다. Objectives : Many studies have demonstrated that suicide is related to low serum cholesterol level, whereas conflicting results have also reported. The aims of the present study are to determine whether suicidal attempters have low lipid concentration and to identify the relationship between suicidal attempt severity and serum lipid levels. Methods: Subjects were 50 suicidal attempters who visited the emergency room in Korea University Medical Center between July 1998 and June 1999. All subjects had been interviewed by psychiatrist and evaluated with Risk-rescue rating, HDRS and BPRS. They were diagnosed as major depressive disorder(n=29), personality disorder(n=19), and schizophrenia(n-=2). Serum lipid levels in 50 suicidal attempters were compared with those in 50 nonsuicidal psychiatric inpatients corresponding to the age, sex and diagnosis of the suicidal attempters. We also examined the Spearman's rank correlations between serum lipid levels and risk-rescue score. Results : The serum total cholesterol level(t=-3.29, p=.001), total lipid level(t=-2.62, p=.01), and LDL level(t=-2.64, p=.011) in suicidal attempters were significantly lower compared with nonsuicidal controls. In major depressive patients, total cholesterol level, total lipid level, and LDL level in suicidal attempters were significantly lower than those of nonsuicidal controls. In personality disorder patients, however, only serum total cholesterol level was significantly lower. Risk-rescue rating score was negatively correlated with serum total cholesterol level(p=.-293, p=.039), and positively correlated with BPRS(p=.544, p<.001), and HDRS(p=.488, p=.001). Conclusion : The lipid levels in suicidal attempter were significantly lower. Suicidal attempt severity was also significantly correlated with serum total cholesterol level. These findings suggest that low serum cholesterol should be related with severs violent suicidal attempt.
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이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김삼용,김영건 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1
We performed a variety of lymphocyte stimulation tests, delayed hypersensitivity skin tests, and enumeration of several lymphocyte subpopulations in 21 patients with gastric cancer who did not receive any form of anticancer therapy, and in 20 healthy controls. The gastric cancer patients had significantly decreased number and total score of positive reactions in delayed hypersensitivity skin tests compared with the healthy controls. The percent of CD_(4) positive lymphocytes in the gastric cancer patients was significantly decreased compared to the normal control subjects, but it had no correlation with the total score of delayed cutaneous hypersensitivity reactions. The ratio of helper to suppressor cells was lower in the cancer group. The uptake of 3H-thymidine was markedly depressed in cancer patients when stimulated with various mitogens. There was little correlation between any of the stimulation tests and any of the lymphocyte subpopulation proportions to delayed hypersensitivity cutaneous reactions. Optimal proliferative response was found in lymphocytes stimulated with 10 micrograms of concanavalin-A and 10 microgram of phytohemagglutinin. Advanced stage patients had greatly depressed delayed hypersensitivity skin reactions and proliferative responses to mitogens compared with localized diseases. These results suggest that gastric cancer patients have depressed cellular immune functions, which mainly result from the decreased helper cells and defects in functional proliferative response to mitogens. Interleukin-2 and interferon-gamma restored the in vitro proliferative response of lymphocyte in patients with gastric cancer.
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