Effect acid glycolic acid alone or combination with UVB on skin iritation and inflammation in guinea pigs

Hong JT,Park KS,Kim HJ,Kim EJ,Jung KM,Ahn KS,Lee JK,Man KT,Kim DJ,Kim YK,Lee SH 大韓藥學會 2000 大韓藥學會 總會 및 學術大會 Vol.49 No.-

한국인의 관동맥질환에 따른 혈중 지질 및 위험인자의 비교 연구

홍순준,오동주,김응주,이승진,신성희,최종일,최철웅,박재석,안정천,박창규,서홍석,노영무 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.6

초산부에서 연령에 따른 분만 및 분만방법의 추세 (1985~1995 년)

이의진,홍완철,고경수,오도산,김형석,박종두 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.6

1985년 1월부터 1995년 12월말까지 만 11년간 성애병원 산부인과에 입원하여 분만한 총 18,160예와 초산부를 대상으로 연령에 따른 임상적 고찰을 통해 다음과 같은 결론을 얻었다. 1. 2985~1995년간 초산부의 평균연령은 26.4세였다. 2. 19세이하의 초산부가 1985년에 0.5%인데 비해 1995년도에는 1.5%로 3배의 증가를 보였다. 3. 35세이상의 노령초산부는 1985년에 0.9%에서 점차 증가되어 1995년도에는 2.0%로 증가되었고 30세이상 초산부의 변화는 8.1%에서 15.2%로 1.9배의 증가를 보였고, 11년간 제왕절개술 시행율은 별다른 변화가 없었다. 4. 태위는 두정위가 17,107예(94.2%)이고 둔위가 1,053예(5.8%)였다. 5. 분만방법은 질식분만이 10,295예(56.7%), 복식분만이 7,865예(43.3%)였다. 6. 제왕절개술식은 자궁협부, 황절개술이 7,831예로 전체의 99.5%를 차지하였고, 체부종절개술은 13예로 0.2%였다. 7. 연령별 제왕절개술은 19세이하 24.1%, 20세~24세 38.1%, 25세~29세 42.8%, 30~34세 54.7%, 35세이상 76.4%로 연령이 증가할 수록 제왕절개술 빈도가 증가함을 알 수 있고 10대에 비해 노령초산부에서 제왕절개술 시행율이 약 3배로 많았다. 8. 제왕절개술의 적응증 중 아두골반 불균형이 59.5%, 둔위가 13.1%, 분만진행의 지연 및 실패가 9.0%, 태아절박증이 6.5%, 임시중독증이 6.4%, 전치태반 2.9%, 쌍태아 2.2%, 태반조기박리 0.4%순이었다. 결론적으로 최근 증가된 10대 초산부에 대한 성교육 및 예방이 필요하며, 경산부에 비해 증가된 초산부의 노령화에 따른 산과의의 산전관리 및 분만방법의 신중한 선택으로 산모와 태아의 분만관련 위험성을 저하시켜 무분별한 제왕절개술의 시행으로 인한 합병증 및 경제적 부담을 주지 않도록 산과의의 적극적인 자세와 노력이 필요하리라 사료된다. With the changing life style of women in current society, there is often postponement of childbearing and the pregnancy rate of teenage and elderly mothers is increasing. Thus the impact of maternal age on delivery outcome and mode becomes important. This study was carried out retrospectively based on the clinical charts of 18,160 primiparous women who had delivered from January, 1985 to December, 1995 at the department of Obstetrics & Gynecology, Sung Ae Hospital. The results obtained were as follows; 1. Total primiparous deliveries were 18,160 cases and the overall incidence of cesarean section was 43.3%. 2. The mean age of total 18,160 delivered primiparous women was 26.4 years. 3. In 1985, the rate of primiparous delivery was 0.5% under 19 years and 0.9% over 35 years, this rate rose to 1.5% under 19 years and 2.0% over 35 years in 1995. The rate was 1.9 times as high in 1995 as in 1985 for mothers age 35 over and 2 times as high for teenage mother. 4. 17,107 cases(94.2%) were vertex presentation, 1053 cases(5.8%) were breech presentation. 5. 10,295 cases(56.7%) delivered vaginally and 7,865 cases(43.3%) abdominally. 6. In the types of operation, lower segmental transverse incision was the most common (99.5%), and classical section was 0.2% in rate. 7. According to maternal age distribution, cesarean section rate was 24.1% in under 19 years group, 38.1% in 20~24 years group, 42.8% in 25~29 years group, 54.7% in 30~34 years group, 76.4% in over 35 years group. 8. The indication for primary cesarean section were cephalopelvic disproportion(59.5%), breech(13.1%), failure to progress in labor(9.0%), fetal distress(6.5%), placenta previa(2.9%), twin(2.2%), placenta abruption(0.4%). 9. Maternal age was a strong determinant of delivery mode in this study ; the Cesarean rate in women aged$gt;35 years was about three times the rate reported in teenagers. In conclusion, delivery outcomes and mode markedly changed for recent 11 years. That changes was increment of teenage mothers and elderly mothers. There was also an increased frequency of cesarean section rate in the older women. Thus maternal age factor is important for delivery outcomes and mode in primiparous women. So careful antenatal and intrapartal care should be performed for the older aged pregnant women and teenage mothers.

자궁내막암 임상 병기Ⅰ과 Ⅱ에서 수술중 동결 절편 진단의 정확도

심재욱,홍성란,정환욱,박인서,임경택,김태진,박종택,이승호,이기헌,김의정 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.5

이상의 결과로 보아 자궁내막암의 수술에 있어 동결 절편 진단을 시행함으로써 집도의가 골반 및 부대동맥 임파절에 암세포 전이의 고위험 요소를 선별할 수 있도록 하여 치료방침 결정에 중요한 역할을 할 것으로 사료된다. From January 1991 to December 1996, a comparative analysis was conducted on 45 consecutive patients underwent hysterectomy for FIGO stage I & II endometrial carcinoma to determine the accuracy of intraoperative frozen section (IFS) diagnosis. The IFS diagnosis and the permanent section diagnosis were compared in myometrial invasion, cervical invasion, adnexal involvement, tumor differentiation, and histological types. In IFS diagnosis, deep myometrial invasion, poor histological type, poorly differentiated tumor, cervical invasion, and adnexal involvement were considered as high risk factors for the pelvic and the paraaortic nodal metastasis. The depth of myometrial invasion (superficial 1/2 vs deep 1/2) was accurately determined by IFS diagnosis in 44 of 45 cases (97.8%). The sensitivity was 93.3%, and the specificity was 96.8%. The following tumor characteristics were also accurately determined by frozen section at surgery: histologic types (91.1%), poorly differentiated tumor (95.6%), cervical invasion (91.1%), and adnexal involvement (100%). One case of deep myomerial invasion, four cases of cervical invasion, and two cases of poorly differentiated tumor were underestimated in IFS diagnosis. 15 of 20 patients (75%) were correctly identified by frozen section at surgery as having high risk for pelvic and paraaortic nodal metastasis. We conclude that IFS diagnosis is an important procedure that enables the surgeon to identify the patients at high risk for the pelvic and the paraaortic nodal metastasis.

불완전 고환성 여성화 증후군 1 예

홍석우(SW Hong),허의종(EJ Hur),박형무(HM Park),김우균(WK Kim),배도환(DH Pai) 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.12

본 중앙대학교 의과대학 산부인과학교실에서는 임상증상 및 내분비학적 검사로 진단된 불완전 고환성 여성화 증후군 1예를 경험 하였기에 간단한 문헌고찰과 함께 이를 보고하는 바이다. Incomplete testicular feminization syndrome is an ill-defined designation used to lescribe a heterogenous group of patients with an atypical form of testicular feminization. As in complete testicular feminization syndrome, the karyotype is XY, bilateral testes and other male internal genitalia are present, and mullerian derivatives are absent; however, unlike individuals with the complete testicular feminization syndrome, the external genitalia are ambiguous rather than that of female and some degree of virilization such as clitorial hypertrophy, partial labioscrotal fusion and hirsutism occurs at puberty. Complete and incomplete testicular feminization syndrome have been shown to be a disorder of androgen receptor function or genomic expression perse. More than 200 cases, complete and incomplete type, have been reported in the world. In our country, four cases of complete type have been reported up to present. We first report a case of incomplete testicular feminization syndrome with the brief review of literatures.

부인과영역에서 골반경수술의 치험 125 예

홍완철(WC Hong),황정범(JB Hwang),한재희(JH Han),박농수(NS Park),조태일(TI Cho),이의진(EJ Lee) 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.5

본원 산부인과에서는 1992년 1월부터 1992년 11월까지 125례의 골반경수술을 시행한 결과 다음과 같은 장점을 얻을 수 있었다. 수술시간 및 입원기간 단축과 조기 사회생활복귀, 그리 고 경비절감의 잇점 이외에도 수술중 출혈 및 술후 유착 등과 같은 합병증이 현저히 적었으 며, 이환율의 감소 뿐아니라 수술상처가 거의 남지않아 부인과영역의 질환들의 대부분이 골 반경수술로 바뀔 것으로 생각된다. The diagnostic and therapeutic applications of operative pelviscopy are numerous. Pelviscopic surgery has been reproted to reduce inpatient hospital time and cost. In addition, to minimize tissue handling and bleeding. Pelviscopic surgery was performed on 125 patients. Who underwent hysterectomy 5, oophorectomy 11, salpingectomy 45, salpingoophorectomy 52, cornuectomy 2, myomectomy 2, adhesiolysis 4, ovary enucleation and wedge resection 2, fluid aspiration and cauterization 2 cases at the department of obstetrics and gynecology, Sung Ae Hospital, from Jan, 1992 to Nov, 1992. In conclusion, pelviscopic surgery was safe and effective in treatment of gynecologic diseases.

Report on the Progress of a Web-based Pharmacist Re-education Program: the Case of Pharmaceutical Care Specialist Program(PCSP)

ES Lee,HK Cho,EJ Hong,JY Yi,SH Lee,HT Shin 대한약학회 1999 大韓藥學會 總會 및 學術大會 Vol.2004 No.1

ABO 혈액형과 융모성질환

민보은,박은주,홍희선,이은희,박영미 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.6

본 연구는 G.T.D. 환자의 혈액형 분포에 현저한 차이가 없는 다른 보고와 비슷한 결과를 보여주었으나, G.T.T. 환자의 다른 보고와는 달리 O형으로 shift되는 양상을 보여주었다. 남편 혈액형 분포는 정상과 의미 있는 차이가 없었으나 AB형으로 약간 shift를 보여주었다. 환자와 남편의 혈액형이 같은 like mating은 uncomplicated mole로 되는 빈도가 높고 포상기태임신후에 G.T.T.가 되는 빈도는 낮음을 보여준다. Unlike mating 중에서 가장 중요한 차이는 O X A와 A X O mating중에서 molar G.T.T.의 비도가 높다는 것이다. 그러나 이러한 mating의 환자에서 사망율은 높지않다. AB형인 포상기태임신 환자 중에서 G.T.T.의 빈도는 낮으나 모든 G.T.T.환자 중에서 사망율은 가장 높았다. 포상기태임신 환자에서 만약 남편이 O형이면 G.T.T.빈도가 약간 더 높고, AB형이면 더 낮은 빈도를 보였다. O형의 남자와 결혼한 환자 중에서 사망율 또한 높았고, 이것은 G.T.T.의 사망율이, fully compatible mating일 때 더 높다는 사실을 반영한다. Studies from different parts of the world have reported differences in the ABO blood group distribution among patients with trophoblastic disease and husbands of these patients and some studies have shown definite influences of the ABO blood group on the outcome. The present study is a report on blood group and mating pattern distribution among 641 patients with hydatidiform mole and husbands of 493 of these patients. The influence of blood group and mating pattern on the prognosis of hydatidiform mole outcome was known in 474 of these patients including 385 in whom the husbands blood group was known . The same study was done on 58 patients with non molar gestational trophoblastic tumor and 25 husbands of these patients. The results were as follows: 1. In patients with G.T.D. there was no marked difference in the distribution of blood groups but in patients with G.T.T. there was a shift towards group O. 2. The distribution of blood groups among the husbands showed some shift towards group AB. 3. There was a decreased incidence of G.T.T. following hydatidiform mole in patients mated with men of the same blood group. 4. Among the unlike matings there was an increased incidence of molar G.T.T. among O x A and A x O matings. However the mortality rate in these patients was not raised. 5. There was no difference in the incidence of G.T.T. between fully compatible and possible incompatible matings but there was a higher mortality rate when the mating was fully incompatible.

완전 좌각 차단이 관상동맥 좌전하행지 혈류에 미치는 영향:경흉부 심초음파를 이용한 연구

박철수,윤호중,조은주,정해억,전희경,오용석,이만영,정욱성,노태호,김재형,최규보,홍순조 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.6

개흉 잡견에서 심방-양심실 조율의 혈역학적 효과

임상현,노태호,조은주,진승원,김희열,이만영,김종진,김재형,홍순조,최규보 대한순환기학회 2001 Korean Circulation Journal Vol.31 No.4