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임동건,정세민,최유신,김도영,이준신 성균관대학교 1997 학술회의지원논문목록집 Vol.1997 No.-
We have investigated Pt and RuO₂as a bottom electrode for a device application of PZT thin film. The bottom electrodes were prepared by using an RF magnetron sputtering method. We studied some of the property influencing factors such as substrate temperature, gas flow ratem and RF power. An oxygen partial pressure from 0 to 50% was investigated. The results show that only Ru metal was grown without supplying any O₂gas. Both Ru and RuO₂phases were formed for O₂partial pressure between 10-40%. A pure RuO₂phasewas obtained with O₂partial pressure of 50%. A substrate temperature from room temperature to 400°C was investigated with XRD for the film crystallinity examination. The substrate temperature influenced the surface morphology and the resistivity of Pt and RuO₂ as well as the film crystal structure. From the various considerations, we recommend the substrate temperature of 300°C for the bottom electrode growth. Because PZT film growth on top of bottom electrode requires a temperature process higher than 500°C, bottom electrode properties were investigated as a functiona of post anneal temperature. As post anneal temperature was increasedm the resistibity of Pt and RuO₂was decreased. However, almost no change was observed in resistibity for an anneal temperature higher than 700°C . From the studies on resistivity and surface morphology, we recommend a post anneal temperature less than 600°C.
임근우,박일영,유승진,나병호,오동렬,전해명,황주일,김세경 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1
We reviewed retrospectively 230 patients who came to emergency room of Kang Nam St. Mary's Hospital and Uijongbu St. Mary's Hospital between 1. January and 31. December 1994. We classified them according to their age, sex, a sort of drug, the cause of poisoning, prehospital care, time-lapse to arrive at hospital after poisoning, psychiatric problem the status of patients. *We conclude as follows; 1. The male to female ratio was totally 1 : 1.98, 1 : 1.24 in a urban area, 1 : 2.43 in a rural area. 2. On age of the patients in this study, the peake incidence was between 20 and 39(55.2%). 3. On seasonal prevalence, the poisoning was most common in summer and spring, in urban area(35.7%) and rural area(37.0%) respectively. 4. The common drug were as follow; Doxylamine, Organophosphate, Acetaminophen in urban area, Paraquat, Organophospate, Doxylamine in rural area 5. The percentage of suicidal attempt were 81.8% and 87.7% in urban area and rural area respectively. 6. The poisoning patients had psychatric problem in 19.4% and 24.6%, in urban area and rural area respectively. 7. Before arrival to emergency room, 27.7% of patient was done prehospital care in rural area. 8. On arrival to emergency room, 95.1% and 73.8% of patients show stable vital sign in urban area and rural area respectively.
운동유발성 아나필락시스 환자에서 혈 중 tryptase 측정 1례
예영민,임선교,서유진,최정희,서창희,남동호,박해심 대한천식 및 알레르기학회 2004 천식 및 알레르기 Vol.24 No.1
Exercise-induced anaphylaxis(EIA) is a medical emergency in that it derives from a physical allergy. We reported a case of food-independent EIA based on history and laboratory data. A 40-year-old male patient was presented with generalized urticaria, angioedema, and syncope after jogging. He had suffered from allergic rhinitis for 25 years. Increased level of serum tryptase was noted. Mast cell activation might be suggested in the pathophysiologic mechanism of EIA. (J Asthma Allergy Clin Immunol 24 : 152-5, 2004)
동종 조혈모세포이식 후 발생한 크립토콕쿠스 척추염 1예
고윤호,임동준,이성수,조유경,이동건,최정현,김유진,민창기,김동욱,박정미,김춘추,신완식 대한감염학회 2001 감염 Vol.33 No.4
Skeletal cryptococcosis is an uncommon infection. Cryptococcus is a common cause of meningitis and infects 7∼10% of patients with AIDS. As well as AIDS, the infection may be seen in association with leukemia, lymphoma, Hodgkin's disease, sarcoidosis, tuberculosis and diabetes, also in patients on steroid medication. But there is no case report of skeletal cryptococcosis following allogeneic hematopoietic stem cell transplantation. A 40-year-old woman was admitted to the hospital because of low back pain. She had chronic myelogenous leukemia for 2 years and underwent allogeneic hematopoietic stem cell transplantation 8 months ago. She have been treated with steroid and cyclosporine orally because of chronic graft versus host disease. On examination she was afebrile and had posterior lower lumbar tenderness. But, she had no reduced strength of low extremities. Open biopsy was underwent. Histology demonstrated budding, round-to-oval, refractile yeast-like organisms within debris. The results of a lumbar puncture were unremarkable and cerebrospinal fluid culture failed to grow bacteria and yeast. The patient was treated with amphotericin B (1 gram) and AmBisome□ (2.8 gram) over 6 weeks. Three months after cessation of therapy, the patient was doing well.(Korean J Infect Dis 33:298∼301, 2001)
Terfenadine과 Ketoconazole 복용 후 발생된 Torsades de pointes 심실 빈맥증의 치험 1례
김세경,이기중,유승진,박일영,박승현,임근우,이원재,강동헌 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1
Torsades de pointes is a form of polymorphic ventricular tachycardia that is associated with prolongation of the QT interval, characterized by QRS complexes of progressively changing amplitude and contour that seem to revolve around the isoelectric line. The most common cause of Torsades de pointes induced by antiarrhythmic agents, occupying in certain drugs or toxin, electrolyte disturbance, congenital QT prolongation syndrome. Cardiotoxicity terfenadine, in overdose a widely used, nonsedating antihistamine, has been reported. Case after administration of terfenadine and ketoconazole causing syncope and torsades de pointes have been reported in recommended dose. We report a case of QT prolongation with torsades de pointes after therapeutic administration of terfenadine, a long acting histamine H1 receptor antagonist, together with ketoconazole, an antifungal preparation. The patient is a 43-year-old female, who experienced palpitation, dizziness and syncopal episoders after coadministration of terfenadine and ketoconazole, for a fungal infection of the skin. The ECG showing typical episodes of torsades de pointes with QT prolongation. Magnesium sulfate was given, torsades de pointes did not recur. The patient was discharged with improved condition.
A-Si:H/Cd 계면층을 이용한 a-Si:H의 결정화 연구
김도영,최유신,임동건,이준신,김홍우,이수홍 성균관대학교 1997 학술회의지원논문목록집 Vol.1997 No.-
We studied the crystallization of a-SiH thin film. Multi crystallized Si fillms are preferred in many applications such as FPD, solar cells, RAM, and integrated circuits. Because most of these applications require a low temperature process, we investigated a crystallization of a-SiH using a Cd layer. A metal Cd shows an eutectic point at a temperature of 321°C. THis paper present Cd layer assisted crystallization of a-SiH film for the various grain growth parameters such as anneal temperature. Cd layer thickness and anneal time.
대퇴 전자간 골절의 내고정시 발생한 천부 대퇴 동맥의 관통 손상 : 증례보고
김기수,류상욱,서유석,임동윤 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.1
The superficial femoral arterial injury due to the internal fixation surgery in intertrochanteric femoral fracture has been reported to be an unusual complication case. Recently, we experienced a case of patient with penetrating injury of superficial femoral artery induced by the internal fixation surgery with a gamma nail in an intertrochanteric femoral fracture. This penetrating injury was successfully treated by the transplantation surgery with an artificial blood vessel, which has been not yet reported. Therefore, we report the present clinical result obtained from the case work with reviewing literature, It seems likely that this case is the first report related to penetrating injury of superficial femoral artery induced by the internal fixation surgery with gamma nail.
RAD2 and PUF4 Regulate Nucleotide Metabolism Related Genes, HPT1 and URA3
Yu, Sung-Lim,Lim, Hyun-Sook,Kang, Mi-Sun,Kim, Mai Huynh,Kang, Dong-Chul,Lee, Sung-Keun The Korean Society of Toxicogenomics and Toxicopro 2008 Molecular & cellular toxicology Vol.4 No.4
Yeast RAD2, a yeast homolog of human XPG gene, is an essential element of nucleotide excision repair (NER), and its deletion confers UV sensitivity and NER deficiency. 6-Azauracil (6AU) sensitivity of certain rad2 mutants revealed that RAD2 has transcription elongation function. However, the fundamental mechanism by which the rad2 mutations confer 6AU sensitivity was not clearly elucidated yet. Using an insertional mutagenesis, PUF4 gene encoding a yeast pumilio protein was identified as a deletion suppressor of rad2${\Delta}$ 6AU sensitivity. Microarray analysis followed by confirmatory RT-qPCR disclosed that RAD2 and PUF4 regulated expression of HPT1 and URA3. Overexpression of HPT1 and URA3 rescued the 6AU sensitivity of rad2${\Delta}$ and puf4${\Delta}$ mutants. These results indicate that 6AU sensitivity of rad2 mutants is in part ascribed to impaired expression regulation of genes in the nucleotide metabolism. Based on the results, the possible connection between impaired transcription elongation function of RAD2/XPG and Cockayne syndrome via PUF4 is discussed.