동일한 혈관 내에 발생한 이식형 약제 주입기 카테터의 위치이상

오대석,김영재,김명훈,조광래,임세훈,이정한,이근무,정순호,신치만 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

저자들은 56세 여성 환자의 왼쪽 쇄골 하 정맥에 시행한 이식형 약제주입기 카테터의 삽입 후 발생한 비정상 위치에 대한 증례를 보고하고자 한다. 카테터의 끝은 환자의 늘 어진 가슴, 체위, 신체의 움직임, 카테터의 유동성 등의 영향으로 천자된 정맥 내에서 견인되고 뒤쪽으로 이동하였다. 환자는 어떠한 증상도 호소하지 않았지만 비정상 위치의 카테터는 심각한 합병증을 유발할 수 있기 때문에 제거되었다. 따라서 시술자는 약제주입기 삽입 전에 환자의 신체 상태와 단순 흉부 촬영상을 확인하고 카테터의 비정상 위치가 발생할 수 있는 위험 징후를 알아차려야 하겠다.

통합교육에서의 장애유아의 적응기술에 대한 교사의 인식

박정훈,강대옥,박재국 한국특수아동학회 2003 특수아동교육연구 Vol.5 No.1

본 연구는 통학교육에서 장애유아의 적용기술에 대한 교사의 인식을 조사하기 위한 것으로 통합교육 프로그램을 준비하고, 실제적인 교육을 수행하는데 필요한 기초자료를 제공하고자 하였다. 부산시 유아교육기관의 일반교사 97명과 특수교사 60명을 대상으로 통합교육에 필요한 적용기술에 대한 인식을 설문지를 이용하여 조사한 결과 다음과 같은 주된 결론을 얻었다. 첫째, 통합교육에서 요구되는 적응기술에 대한 인식에서는 일반교사와 특수교사 사이에 차이가 없었으나, 하위 영역에서 특수교사들이 일반교사보다 적응기술의 중요성을 높게 평가하고 있다. 둘째, 통합교육에서 요구되는 적응기술의 하위영역에서 특수교사들은 집단활동 참여기술을 가장 중요하게 인식하고 있으나, 일반교사들은 독립생활기술을 가장 중요하게 인식하고 있다. 셋째, 장애유아 적응기술에 대한 교사변인에 따른 인식차이에서 통합경험이 없는 교사들이 적응기술을 중요하게 인식하고 있으며, 특수교육관련 연구경험이 없는 교사가 연수경험이 있는 교사보다 적응기술을 더 중요하게 인식하고 있다. 넷째, 성공적인 통합교육을 위한 교사의 의견에서는 교사의 긍정적 인식 및 태도를 가장 중요한 요인으로 인식하고 있으며, 학부모의 긍정적인 인식과 일반유아의 이해도 주요하다고 인식하고 있다. n This study aimed to determine teachers recognition of the adaptation skills of handicapped children for mainstream education and to provide basic materials for the successful execution of the programs to be prepared for mainstream education and actual mainstream education. This study considered 97 preschool teachers and 60 special teachers who were selected using random sampling, in Busan Metropolitan City. Questionnaires were distributed and collected, with responses reviewed and analyzed using SPSS Win 10.0. Results show no significant difference in the recognition of general adaptation skills of handicapped children required in mainstream education between special teachers and preschool teachers. In contrast, there is difference between the two groups in the sub-spheres of adaptation skills, in which spheres the importance of adaptation skills was more highly regarded by special teachers in the actual kindergarten education than ordinary kindergarten teachers thought. On the other hand, special teachers valued skills of participating in group activities the most in the sub-spheres of adaptation skills required in mainstream education while preschool teachers prioritized independent skills. To narrow such difference in recognition, correct understanding of and active exchange of information in mainstream education should be developed. In addition, teachers without experience in mainstream education were found to require a higher level of adaptation skills from handicapped children compared to teachers with experience in mainstream education. Likewise, teachers without educational training valued adaptation skills more compared to teachers with educational training. Both special teachers and preschool teachers expected a higher level of adaptation skills from handicapped children compared to mainstream education teachers. This suggests that special teachers or teachers without experience in mainstream education demanded a higher level of adaptation skills than actually necessary in mainstream education. The recognition of teachers also varied depending on the educational institution they belong. Finally, teachers considered the positive recognition and attitude of teachers, positive recognition of students parents, and understanding of children as mojor contributory factors to successful mainstream education.

Kano 모형에 기반한 소비자 요구사항 분류 : 퍼지 접근방법

임정훈,민대기,김광재 한국품질경영학회 2003 품질경영학회지 Vol.31 No.3

Kano model distinguishes three types of customer requirements, namely, one-dimensional quality, must-be quality, and attractive quality. There are a few methods for classifying a given customer requirement into one of the Kano's quality elements. However, the existing methods have a common limitation in that they are based on Kano evaluation table. Kano evaluation table is not always effective for the classification task, and suffers from a significant information loss. This paper proposes an alternative to Kano's evaluation table and a new classification scheme based on fuzzy set concept. The proposed method is illustrated using a case study on the ADSL service.

말기신부전 환자에서 혈액투석 전후의 QT간격분산 비교

강대웅,정지용,윤나라,안치용,김종오,신병철,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Background: Some cases of QT interval, corrected QT interval (QTc), QT dispersion (QTd) and corrected QT dispersion (QTcd) have been reported in ESRD, but these results are variable and the influence of a hemodialysis is still controversial, In this study, we investigated the effect of hemodialysis on QT and QTc interval and QT and QTc dispersion in patients with ESRD 15 min before and 15 minute after each hemodialysis. Methods: Sixty-seven patients with ESRD (men 33 & women 34) on three-times stable hemodialysis (>3 months) were randomly enrolled. Fifty control subjects with a similar age and normal renal function were enrolled from this hospital. Routine biochemical studies were measured pre- and post dialysis, at the time of the ECG. Plasma Na+, K+, BUN, creatinine, ionized calcium and phosphate were checked. Twelve-lead electrocardiographs were performed at 10㎜/mv and 50㎜/s using a HewIett-Packard Pagewriter 100, before and after a single hemodialysis session.The QT interval was measured from the onset of the QRS complex to the end of the T wave. If the end of the T wave was not clear in a particular lead then it was excluded from analysis. When U waves were present, the end of the T wave was taken as the nadir between the T and U waves. Each QT interval was corrected for heart rate using Bazett's formula (QTc==QT/√(RR)) (ms). The difference between maximal and minimal QT interval duration was defined as QT dispersion (QTd) in each of the 12 leads. Result: This study demonstrates that QT, QTd, QTcd is higher in hemodialysis patients compared with control subjects, and QT and QTd rise postdialysis to levels comparable to those seen acutely following myocardial infarction, when patients are at greatly increased risk of potentially fatal ventricular arrhythmias, Conclusions: QT interval and QT dispersion, markers of risk for arrhythmias and sudden death, are elevated in hemodialysis patients, and rise postdialysis. QT interval and QT dispersion is an easily obtainable, noninvasive, simple, inexpensive, and widely available method of risk stratification in uremic patients receiving chronic dialysis. Additional studies are needed to clarity whether increased postdialysis QT dispersion results in an increased occurrence of arrhythmias.

분자역학적 방법을 이용한 부산시내 대형건물 냉각탑수의 레지오넬라균의 형별 분류

김정만,정석훈,서대영,박은희,송은주,최재철,이은엽,장철훈 대한임상미샐물학회 2004 Annals of clinical microbiology Vol.7 No.1

齒科用 非貴金屬合金의 物理的 性質에 미치는 鑄型溫度의 影響

盧正剋,曺光憲,李基大 慶北大學校 齒科大學 1986 慶北齒大論文集 Vol.3 No.1

齒料用 非貴金屬合金으로 널리 使用되고 있는 니켈 - 크롬系 合金인 Ticonium Premium 100 과 코발트 - 크롬系 合金인 Regalloy를 對象으로 500, 600, 700, 800, 900 및 1,000℃의 鑄型溫度로 變化시켜 遠心鑄造한 後, 硬度 및 引張强度를 測定하고 微細組織과 引張試 片破斷面을 觀察하여 아래의 結果를 얻었다. 니켈 - 크롬系 合金인 Ticonium Premium 100은 鑄型溫度가 上昇할수록 結晶粒이 粗大하게 變化함에 따라 硬度 및 引張强度도 多少 減少를 나타내었다. 코발트 - 크롬系 合金인 Regalloy는 鑄型溫度가 上昇할수록 結晶粒이 粗大하게 變化함에 따라 硬度 및 引張强度의 顯著한 減少를 나타내었다. 코발트 - 크롬系인 Regalloy는 니켈 - 크롬系인 Ticonium Premium 100에 비해 硬度인 引張强度가 높게 나타났다. 引張試片 破斷面은 두 合金 모두에서 鑄型溫度가 上昇할수록 微細氣孔이 破斷面의 中心部에 集中되는 傾向이 增加하였으며 延性破斷에서 脆性破斷으로 轉移되는 樣相을 觀察할 수 있었다. 良質의 鑄造組織을 얻고 鑄造體의 適合性을 向上시키기 위해서는 適切한 材料에 따른 適切한 鑄型溫度의 選擇이 要求된다. The purpose of this study was to investigate the effect of mold temperature on the change in microstructure and physical properties of Ticonium Premium 100 (Ni-Cr alloy) and Regalloy (Co-Cr alloy). Tensile and hardness specimens were casted from the two types of alloys by centrifugal casting machine in mold temperatures of 500, 600, 700, 800, 900 and 1,000℃. After testing the hardness and the tensile strength of castings, the microstructure and the pattern of fracture were investigated and correlated with the above two mechanical properties. The results were as follows : As the grain size of Ticonium Premium 100 increased with the increase of mold temperature, the hardness and the tensile strength reduced slightly with the increase of grain size. As the grain size of Regalloy increased with the increase of mold temperature, the hardness and the tensile strength reduced remarkably with the increase of grain size. The values of hardness and tensile strength obtained from Ticonium Premium 100 were lower than those from Regalloy.

EPC 주강품의 Carbon Pick-up 현상

박익민,김대석,김정훈 한국주조공학회 2005 한국주조공학회지 Vol.25 No.1

혈액투석중인 말기신부전 환자에서 Fludrocortisone acetate (FCA) 투여 후 혈청 칼륨 저하 효과

류봉관,강대웅,정지용,윤나라,신병철,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Background: Hyperkalemia is a commonly encountered problem in dialysis patients with end-stage renal disease. In this study we evaluated the effect of mineralocorticoid therapy (fludrocortisono acetate) on serum potassium level in the serum of hyperkalemic end-stage renal disease patients. Methods: Fourteen patients on hemodialysis receiving fludrocortisone acetate (FCA) 0.1 mg/day were observed for 2 months periods. Consecutive monthly biochemical profiles were compared for the druration of the pre-and post-treatment of FCA. Result: Fourteen patients with mean age (±SE) of 51.5 years (4 males and 10 females) and mean hemodialysis period of 51.9 months were studied. Mean serum potassium levels significantly fell (p<0.05) during the post-FCA period (5.2±0.66 mEq/L) compared with potassium levels during the pre-FCA (5.8±0.43 mEq/L) period. Pre-and post-FCA values were not different for sodium, chloride, protein, albumin, AST/ALT, glucose, blood nitrogen, creatinine, phosphate and calcium. Conclusions: FCA appears to decrease serum potassium value in patients with end-stage renal disease. These results suggested that FCA could be effective to treat hyperkalemia without any adverse effect in patients undergoing hemodialysis.

Characterization of a Dual-Specificity Protein Phosphatase, Human DUSP28

Dae Gwin Jeong(정대균),Song Yi Kim(김송이),Jeong Hun Yun(윤정훈),Jae Hoon Kim(김재훈) 한국생명과학회 2011 생명과학회지 Vol.21 No.1

Dual-specificity protein phosphatase (DUSP)들은 인산화된 티로신 잔기와 인산화된 세린 또는 트레오닌 잔기를 탈인산화시키는 단백질 탈인산화효소 군을 이루고 있으며, 대부분의 DUSP들은 세포의 생존이나 분화에 관여하고 있다. 본 연구에서는 잘 알려지지 않은 인간 유래의 dual-specificity protein phosphatase인 DUSP28을 인간신장 cDNA에서 분리하였다. 대장균에서 생산된 재조합단백질은 6,8-difluoro-4-methylumbelliferyl phosphate(DiFMUP)에 대하여 좋은 활성을 보였다. 다양한 저해제와 2가 금속이온들이 DUSP28의 활성에 미치는 영향을 조사하였다. 다른 DUSP들에서와는 다르게, Zn<SUP>2+</SUP>은 DUSP28의 탈인산화활성을 강하게 억제하였다. 이러한 결과로부터 DUSP28이 Zn과 연관된 신호전달경로에 관여할 것으로 추정된다. 더욱이, DUSP28은 인산화된 티로신 잔기를 더욱 선호하는 경향이 있는 것으로 나타났고, 이는 세포 내에서도 비슷한 작용을 할 것으로 예상된다. Dual-specificity protein phosphatases (DUSPs) constitute a family of protein phosphatase characterized by the ability to dephosphorylate phospho-tyrosyl and phospho-seryl/threonyl residues. Most DUSPs are involved in regulation of cell survival and differentiation. In this study, a human dual-specificity protein phosphatase, DUSP28, was isolated from a human kidney cDNA. The recombinant protein was successfully produed in E.coli and showed sufficient phosphatase activity toward DiFMUP (6,8-difluoro-4-methylumbelliferyl phosphate). Various phosphatase inhibitors and divalent metals were tested for their effects on the DUSP28 phosphatase activity. As a result, Zn<SUP>2+</SUP> was found to strongly inhibit DUSP28 phosphatase activity, suggesting DUSP28 is involved in Zn-related signal transduction pathway. Furthermore, the DUSP28 protein preferred phospho-tyrosyl residues to phospho-threonyl residues, implying its physiological roles in the cellular process.

Unexpected finding of Pseudococcus orchidicola (Hemiptera: Pseudococcidae) in search of P. viburni and P. longispinus in Korea

Dae-Hun Jeong,Seulki Kim,Hyun Kyung Kim,Hyun-Na Koo,Gil-Hah Kim,Soowon Cho 한국응용곤충학회 2017 한국응용곤충학회 학술대회논문집 Vol.2017 No.10

We investigated if Pseudococcus viburni and P. longispinus, the two notorious pest species of mealybugs are foundin Korea. Our survey involved a total of 602 sites all over the country for the last three years. Pseudococcus viburniwas only once referred in Gimpel’s 1983 dissertation on P. affinis group: only one record was noted from Korea amongmany specimens from various countries. However, the species has never been reported from Korea for the last severaldecades and none was found in our thorough survey. We believe there was a misidentification, as noted by the authorregarding the species complex, and conclude that P. viburni does not occur in Korea. On the other hand, P. longispinushas been found in 36 sites, all from imported tropical houseplants in a green house or nurseries. In addition, anothersimilar species has been found from 86 sites. This unknown species was surprisingly best matched with P. orchidicola.Both species could not survive Korea’s harsh winter and they could only survive in a temperature-controlled place suchas nurseries and restaurants.