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RISS 인기검색어
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- 저자 : 신정원(Jeong Won Shin) (검색결과 30 건)
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신정원,허민석,이삼선,최순철,박태원,Shin Jeong-Won,Heo Min-Suk,Lee Sam-Sun,Choi Soon-Chul,Park Tae-Won 대한영상치의학회 2000 Imaging Science in Dentistry Vol.30 No.2
Pyogenic granuloma is a overzealous proliferation of a vascular type connective tissue as a result of some minor trauma and is a well circumscribed elevated, pedunculated or sessile benign inflammatory lesion of skin and mucous membrane. The clinical features of pyogenic granuloma are indicative but not specific and nearly all cases of pyogenic granulomas are superficial in nature, and there is little if any mention in the literature of these lesions producing alveolar bone even jaw bone loss. This case is somewhat unique in that the lesion was an obvious histologic pyogenic granuloma; however, it appeared to invade the mandibular bone which resulted in the loss of the adjacent teeth. A 12-year-old boy came to Seoul National University Dental Hospital with chief complaints of left facial swelling. The features obtained were as follows; Plain radiograms showed a large well-circumscribed radiolucent lesion on left mandibular ramus area, which made severe expansion of lingual cortex and displacement of lower left 3rd molar tooth germ. Computed tomograms showed large soft tissue mass involving left masticator space with destruction of left mandibular ramus. Histologically, sections revealed loose edematous stroma with intense infiltration of inflammatory cells and proliferation of vascular channels. Also, there were focal areas of extensive capillary proliferation, bone destruction and peripheral new bone formation.
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Tranexamic Acid를 주성분으로 하는 경구약제의 기미치료 효과연구
신정원 ( Jung Won Shin ),허선영 ( Sun Young Huh ),정정복 ( Jeong Bok Jeong ),박경찬 ( Kyoung Chan Park ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7
Background: Melasma causes considerable cosmetic disfigurement and none of the existing treatment modalities are satisfactory. Recently tranexamic acid has been reported to reduce hyperpigmentation in patients with melasma. Objective: The purpose of the study was to evaluate the efficacy and safety of tranexamic acid containing oral medication for the treatment of melasma. Methods: Forty-five female volunteers who had been diagnosed with melasma were enrolled in the present study. Patients were instructed to take medication for 8 weeks. The melanin index (MI) and erythema index (EI) were measured at baseline, and at 4 and 8 weeks. The melasma area and severity index (MASI) was scored at 0, 4, and 8 weeks. Self-satisfaction and safety evaluations were also performed at each visit. Results: The mean MI measured on the lesional skin was decreased at 4 and 8 weeks compared with baseline (p<0.01 for both). The mean EI measured on the lesional skin and the MASI also showed a significant decrease from baseline to 8 weeks (p<0.001 for EI and p=0.020 for MASI). Based on self-assessment, 39.5% of the patients were very satisfied, 44.2% were satisfied, and 11.6% felt moderate improvement after 8 weeks of medication; only 2 patients (4.7%) were dissatisfied. Thus, >80% of patients were satisfied with the medication. Adverse effects were minimal and two patients dropped out of the study due to drug-related urticaria and unexpected pregnancy. Conclusion: Tranexamic acid-containing oral medication is an effective and safe therapeutic modality for the treatment of melasma.
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신정원(Jeong Won Shin),박은주(Eun Jo Park) 한국복식학회 1989 服飾 Vol.13 No.-
The purpose of this study was to identify the predictable variables of criteria on clothing selection. Relationships among criteria on clothing selection, psychological variable, lifestyle variable, and demographic variable were tested by Pearsons` correlation coefficients and One-way ANOVA. The predictors of criteria on clothing selection were identified by Regression. The consumers were classified into several benefit-segments by criteria on clothing selection, and then, the character of each segment were identified by Multiple Discriminant Analysis. Data was obtained from 593 women living in Pusan by self-administered questionnaires. The results of the study were as follows ; 1. Relationship between criteria on clothing selection and relative variables. 1) The important variables to criteria on clothing selection were 「down-to-earth-sophisticated」, 「traditional-morden」, 「conventional-different」, 「conscientious-expendient」, need for exhibitionism, need for sex, fashion/appearance. 2) The important factor of clothing selection criteria was comfort and it has significant difference among ages. 3) The higher of social-economic status have the more appearance-oriented selection. 2. Predictors of criteria on clothing selection. There were several important predictors of criteria on clothing selection like lifestyle, need, and self-image. Especially, fashion/appearance in lifestyle variable was very important. 3. Segmentation by the criteria on clothing selection. There are four groups Classified by the criteria on clothing selection, that is practical-oriented group, appearance-oriented group, practical and appearance-oriented group, and indifference group. The significant discriminative variables were Fashion/appearance factor, need for exhibitionism, and need for sex. The result of this study can be used for a enterprise to analysis the consumer and to build the strategy of advertisement clothing.
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지연성 운동장애와 5-$HT_{2A}$ 수용체 유전자 T103C 다형성과의 관계
한상우,신정원,최태윤,우성일,정한용,정희연,한선호,Hahn, Sang Woo,Shin, Jeong Won,Choi, Tae Youn,Woo, Sung Il,Jung, Han Yong,Jung, Hee Yeoun,Han, Sun Ho 대한생물정신의학회 2003 생물정신의학 Vol.10 No.2
Objective:Some candidate gene polymorphisms were reported to be associated with tardive dyskinesia (TD). The aim of this study was to investigate the association of the 5-$HT_{2A}$ receptor gene polymorphisms with TD in Korean schizophrenic subjects. Method:Subjects were of 59 schizophrenic patients with TD and 60 schizophrenic patients without TD for studying of 5-$HT_{2A}$ receptor gene polymorphisms. TD was evaluated using the Abnormal Involuntary Movement Scale(AIMS). Genomic DNA was amplified by PCR and digestion with MspI and BsmI. Result:There were no statistically significant differences in the demographic variables, such as age, male to female percentage, duration of illnesses and duration of antipsychotic drug exposure between the TD group and control group. 1) T102C polymorphisms and TD Comparing the TD group and control group, the 102T/C allele was associated with a significantly increased risk for TD (${\chi}^2$=5.560, df=1, p=0.018). 2) Three AIMS categories of TD and T102C genotype. There were statistically significant differences in the three AIMS categories(${\chi}^2$=6.835, df=2, p=0.033). Conclusion:These result suggest 102T/C genotypes of the 5-$HT_{2A}$ receptor gene are related to the development of TD. The 102T/C genotypes were associated with significantly higher AIMS orofacial dyskinesia scores. These findings suggest that the 5-$HT_{2A}$ receptor gene is significantly associated with susceptibility to TD in patients with chronic schizophrenia.
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특발성 폐섬유증의 통합의료 협진 모델 개발을 위한 의료진 및 환자 대상 설문조사 연구
박지원,이범준,신정원,진수현,양정민,김수덕,김관일,최혜숙,정희재,Jiwon Park,Beom-Joon Lee,Jeong-Won Shin,Su-Hyun Chin,Jung-Min Yang,Sooduk Kim,Kwan-Il Kim,Hye Sook Choi,Hee-Jae Jung 대한한방내과학회 2023 大韓韓方內科學會誌 Vol.44 No.3
Objective: In this study, a questionnaire survey was conducted for doctors and patients to obtain basic data necessary for the development of an integrated medical system for idiopathic pulmonary fibrosis (IPF). Methods: Questionnaires were developed separately for doctors and patients through an expert group meeting. The survey subjects were recruited online and offline, and finally, responses from 231 doctors and 59 patients were used for statistical analysis. Results: The most important parts in the treatment of IPF for both doctors and patients were the "improvement of respiratory symptoms," "improvement of quality of life," and "prevention of disease progression." Antifibrotic agents were prescribed at a high rate, and 100% of the specialists in Western medicine (WM) and 45.8% of patients reported experiencing side effects. As for the additional payment costs that patients considered as affordable for an integrated medical system, "under 50,000 won (about 38$)" was reported the most in both doctor and patient groups. With regard to the reasons for their reluctance to recommend an integrated medical system for IPF, specialists in WM responded highly to "uncertain evidence for treatment effectiveness." Regarding complementary and alternative medicine therapies that can be beneficial in patients with IPF, "lifestyle management," "diet management," "herb," "relaxation therapy," and "psychotherapy" were ranked high in both doctor and patient groups. Conclusions: In this study, a questionnaire survey on IPF was conducted to review actual treatment status, analyze shortcomings, and identify considerations for the development of an integrated medical system for IPF in the future.
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일개 대학병원 신경외과중환자실에서 Clostridium difficile 관련 설사 감소를 위한 CQI활동
박은숙,장경희,윤영옥,이정신,김태곤,여한승,김선호,신정원,이경원,김준명,Park, Eun Suk,Chang, Kyung Hee,Youn, Young Ok,Lee, Jung Sin,Kim, Tae Gon,Yea, Han Seung,Kim, Sun Ho,Shin, Jeong Won,Lee, Kyungwon,Kim, June Myung 한국의료질향상학회 2001 한국의료질향상학회지 Vol.8 No.2
Background : The Clostridium difficile is the most important identifiable cause of nosocomial infectious diarrhea and colitis, which lengthens hospital stay. Recently incidence of C. difficile has been increasing in an university hospital, and an intervention for prevention and control of C. difficile associated diarrhea (CDAD) was in prompt need. Methods : Subjects were the patients in the neurosurgical intensive care unit(NCU) where C. difficile was most frequently isolated. To increase participation of various departments, we used the CQI method, because management of CDAD requires a wholistic approach including control of antibiotics, barrier precaution and environmental cleaning and disinfection. Duration of the CQI activities was 9 months from April to December 1999. Results : The identified problems were misuse and overuse of antibiotics, lack of consciousness of medical personnels and the possibility of transmission from the contaminated environment and tube feeding. Education for proper use of antibiotics and management of C. difficile infection, use of precaution stickers, supplement of handwashing equipments, emphasis on environmental disinfection, and the change of the process of tube feeding were done. The CDAD rate in NCU was significantly decreased after the CQI program (8.6 case per 1,000 patient days from January to April 1999 vs 4.8 from May to December 1999). The distribution of neurosurgical wards including NCU among the total number of isolated C. difficile from the clinical specimens dropped from 49.4% in January to April to 33,7% in May to December. The average hospital stay of the neurosurgical department changed from 19.6 days to 15.2 days. Also, the effect of the CQI activities for C. difficile may have affected the incidence of vancomycin resistant enterococci (VRE). Duration and dosage of certain antibiotics used in the NS department were decreased. The distribution of neurosurgical department in the number of VRE isolated patients declined from 18.4% to 11.1%. Conclusion : Infection control of resistant organisms such as C. difficile is likely to be successful when management of environmental contamination an collaborative efforts of decreasing the patients' risk factors such as antibiotics management and decreasing the length of hospital stay come simultaneously. For this work, related departments need to actively participate in the entire process under a common target through discussions for identifying problems and bringing up solutions. In this respect, making use of a CQI team is an efficient method of infection control for gathering participation and cooperation of related departments.
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서영익 ( Young Ik Seo ),최태윤 ( Tae Youn Choi ),신정원 ( Jeong Won Shin ),원종호 ( Jong Ho Won ),이상철 ( Sang Cheol Lee ),박희숙 ( Hee Sook Park ),이남수 ( Nam Soo Lee ),박노진 ( Ro Jin Park ) 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.1
We report a case of acute myeloid leukemia with multilineage dysplasia accompanying malignant pleural effusion. A 73 year-old male patient was admitted complaining of febrile sensations and right chest pain. The cytology of the pleural fluid revealed malignant pleural effusion showing many blasts, which had previously been identified in his bone marrow when he was diagnosed with acute myeloid leukemia with multilineage dysplasia two months earlier. His age and poor general condition had precluded chemotherapy with the exception of hydroxyurea and conservative treatment. Unfortunately, he succumbed to the disease 4.5 months after diagnosis. This case highlights the importance of determining if the pleural effusion of acute leukemia is malignant or not because it can suggest a pleural metastasis and influence the prognosis.
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