喀痰에 關한 東西醫學的 文獻考察

鄭熙才,鄭昇杞,李珩九 대한한방성인병학회 1995 韓方成人病學會誌 Vol.1 No.1

Depantment of pulmonary Internal Medi-cme, College of Oriental Medicme, Kyung Hee University. Seoul Korea I could come to the conclusion like the following after studying many western and eastern books on sputum. 1. Sputum is a kind of tangible dirty pathogenic fliud secreted by respiratory tract, and mucous which is mixed substance of secretion from trachea and bronchus and foreign body. And it is expectorated or swallowed after moved to pharynx by ciliary movement 2. In oriental Medicme, there are wind, cold, damp, hot, dry stagnant, Qi sputm, while in western medicne, mucus, serous, purulent, bloody. 3. Morphologically, cold and damp sputum are similar to mucous sputum, wind sputum to serous, and hot, dry and stagnant sputum to purulent or mucopurulent. The classification of sputum by observing and comparing type, color and amount of sputum might be of great use to inspection of respiratory disorders.

소청룡탕치료 기관지천식환자의 혈액내 호산구수와 혈청IgE 및 T림프구아형의 변화

정희재,주창엽,이재성,이경기,이형구,정승기,황우석,Jung, Hee-Jae,Ju, Chang-Yeop,Lee, Jae-Sung,Lee, Kyung-Ki,Rhee, Hyung-Koo,Jung, Sung-Ki,Hwang, Woo-Suck 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.1

Background : Nowadays asthma is considered to be an inflamatory disease characterized by airborne hyper-responsiveness and pulmonary eosinophilia. Objective : We aimed to identify the effects of Sochongryongtang on blood eosinophil, serum IgE and T lympocyte subpopulation in asthmatic patients. Material and Methods : The subjects consisted of fifteen patients with asthma who had been treated with Sochongryongtang for two weeks from February 2001 through June 2001. Sochongryongtang is herbal decoction which has been used for the traditional therapeutic agent of asthma. Results : The blood eosinophil and serum IgE in a normal controlled group. However, the T lympocyte subpopulation in asthmatic patients was not significantly different from the T lympocyte subpopulation in a normal group. The patients were treated with Sochongryongtang for two weeks. No significant difference in the blood eosinophil, serum IgE and T Iympocyte in the sub population. After treatment with Sochongryongtang for two weeks, FEV 1 increased significantly over 0.5 points out of total scores. Conclusion : This study shows that Sochongryongtang has effects on improvement of pulmonary function and quality of life in asthmatic patients. However, the patients who were treated with Sochongryongtang for two weeks showed no significant difference in the blood eosinophil, serum IgE and T lympocyte subpopulation. Further long-term studies must be made on a large number of asthmatic patients.

3D Laser Scanning을 활용한 화재 손상 부위의 보수·보강 물량 산출 방식 개선에 관한 연구

정희재,함남혁,이병도,박광민,김재준 한국BIM학회 2019 KIBIM Magazine Vol.9 No.1

Recently, there is an increase in fire incidents in building structures. Due to this, the importance of fire-damaged buildings’ safety diagnosis and evaluation after fire is growing. However, the existing fire-damaged safety diagnosis and evaluation methods are personnel-oriented, so the diagnostic results are intervened by investigators’ subjectivity and unquantified. Thus, improper repair and reinforcement can result in secondary damage accidents and economic losses. In order to overcome these limitations, this study proposes using 3D laser scanning technology. The case analysis of fire-damaged building structures was conducted to verify the effectiveness of accuracy and manpowering by comparing the existing method and the proposed method. The proposed method using 3D laser scanning technology to obtain point cloud data of fire-damaged field. The point cloud data and BIM model is combined to inspect the fire-damaged area and depth. From inspection, quantified repair and reinforcement quantity take-off can be acquired. Also, the proposed method saves half of the manpowering within same time period compared to the existing method. Therefore, it seems that using 3D laser scanning technology in fire-damaged safety diagnosis and evaluation will improve in accuracy and saving time and manpowering.

컴퓨터는 바보

정희재,Jeong, Hui-Jae 한국IT전문가협회 1987 소프트웨어세계 Vol.1 No.-

사람 Mast cell에서의 케모카인에 대한 백연치효탕(白蓮治哮湯)의 효과(效果)

정희재,이형구,정승기,이형철,Jung, Hee-Jae,Rhee, Hyung-Koo,Jung, Sung-Ki,Lee, Hyung-Chul 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4

Background : Although the pathophysiology of asthma has been reported, its mechanism has not been fully elucidated. The mast cell is an effector cells in allergic inflammation and secretes a number of chemokines. Chemokines are important for the recruitment of leukocytes to sites of infection, which is essential in host defense. Chemokines also contribute to the pathogenesis of several disorders such as asthma, chronic bronchitis, atopic dermatitis, allergic rhinitis, and rheumatoid arthritis. Objective : In this study, the aim was to identify the effect of Baekryunchihyo-tang(白蓮治哮湯) on expression of chemokines. This was examined by RT-PCR using the human mast cell line (HMC-l) Materials and Methods : HMC-l cells were used, which is known to secrete and express chemokines. In order to investigate the protective effect of Baekryunchihyo-tang(白蓮治哮湯), HMC-l cells were incubated with pretreatment of Baekryunchihyo-tang(白蓮治哮湯) for 24 hrs. RT-PCR analyses of chemokine genes of cells pretreated with Baekryunchihyo-tang(白蓮治哮湯) showed that expressions of IL-8, $MIP-l{\beta}$, and RANTES genes in these cells were lower and $MIP-l{\alpha}$ showed a similar pattern compared to the calcium ionophore-treated group. In addition, cell cytotoxicity concentration measurements were performed by MTT assay method. Results : After stimulation with 1 uM calcium ionophore A23178 for 2 hrs, IL-8, major one of CXC chemokines, was highly expressed, and expression of $MIP-l{\beta}$ and RANTES (CC chemokines) increased, while expression of $MIP-l{\alpha}$ did not change. The cell cytotoxicity of Baekryunchihyo-tang(白蓮治哮湯) with treatments at various concentrations and times was not observed, respectively. Conclusion : This study suggests that Baekryunchihyo-tang(白蓮治哮湯) has dose-dependent effects on mRNA expression of IL-8(CXC chemokines), $MIP-l{\beta}$ and RANTES(CC chemokines) in human mast cellline(HMC-l). So these herbal medicines may inhibit the inflammatory process of asthma. Advanced studies are required to investigate the mechanism of inhibition by herbal medicine in the asthma model. This study provides basic data on the possibility of the clinical treatment of Baekryunchihyo-tang(白蓮治哮湯) for allergic disorders.

저탄소 마을 조경계획 방안 - 양평군 오빈리를 대상으로

정희재,조현길 한국환경과학회 2017 한국환경과학회 학술발표회 발표논문집 Vol.2017 No.11

사백산(瀉白散)과 사백산가사삼(瀉白散加沙蔘)이 인간 기관지상피세포의 IL-6, IL-8 및 GM-CSF 발현에 미치는 영향

정희재,정승기,이형구,정광진,Jung, Hee-Jae,Jung, Sung-Ki,Rhee, Hyung-Koo,Chung, Kwang-Jin 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.1

Objective : We aimed to identify the dose-dependent inhibitory effects of Sabaek-san(瀉白散) and Sabaeksan plus Sasam(Adenophorae Radix) 瀉白散加沙蔘) on the mRNA expressions of Interleukin(IL)-6, IL-8 and granulocyte macrophage colony stimulating factor(GM-CSF) involved in the asthma model. Materials and Methods : Through this study, BEAS-2B cell lines, human epithelial cells were used. These cells were stimulated by tumor necrosis factor(TNF)-${\alpha}$, IL-1${\beta}$ and histamine for artificial inflammatory expression. ${\beta}$-action messenger RNA(mRNA) was used for standards. After each 24hours of Sabaeksan and Sabaeksan plus Sasam treatment, total cellular RNAs were collected by treating RNA zol directly on living cells, Then the transcriptional activities of IL-6, 8 and GM-CSF were measured by RT-PCR with electrophoresis, Results : The mRNA expressions of IL-6 are significantly inhibited compared to those of controlled group at 40 and 100ug/ml of Sabaeksan extract and $100{\mu}g/ml$ of Sabaeksan plus Sasam extract (p<0.05). The mRNA expressions of IL-8 are significantly inhibited compared to that of controlled group at 2.40 and 100 ug/ml of Sabaeksan extract and $40.100{\mu}g/ml$ of Sabaeksan plus Sasam extract(p<0.05) THe mRNA expressions of GM-CSF are significantly inhibited compared to those of the controlled group at $100{\mu}g/ml$ of Sabaeksan extract adn $40.100{\mu}g/ml$ of Sabaeksan plus Sasam extract.(p<0.05) Conclusions : This study shows that Sabaeksan and Sabaeksan plus Sasam have dose-dependent inhibitory effects on the mRNA expressions of IL-6, IL-8 and GM-CSF in human epithelial cells. Therefore, these types of herb medicine may inhibit the inflammatory process of asthma. Advanced studies are required to investigate the mechanisms of inhibition by herb medicine in the asthma model.

성음(聲音)과 언어(言語)에 관(關)한 문헌적(文獻的) 고찰(考察)

정희재,오태환,정승기,이형구,Jeong, Hee-Jae,Oh, Tae-Hwan,Jung, Sung-Gi,Rhee, Hyung-Koo 대한한방내과학회 1991 大韓韓方內科學會誌 Vol.12 No.1

The results of the investigation of literature were summerized as follows ; 1. Information of voice, the pharynx, the larynx, the epiglottis, the uvula and the hyoid bone were concerned. 2. In disorders of voice and speech, Lung channel, Stomach channel, Spleen channel, Heart channel, Liver channel, Kidney channel, Im channel (任脈), and Chung channel (衝脈) were concerned. 3. The disorders of voice and speech were showed as follows ; aphonia, ashasia, seong-shi (?嘶), seom-eo(?語) kwang-eo (狂語), jeong-seong (鄭?), dok-eo (獨語) and chak-eo (錯語). 4. The cause of Aphonia and Aphasia were freauently as follows ; abnormal rising of Liver energy (肝邪暴逆), excessive heart fire (心火太過), deficiency of heart-blood (心血太虛), apoplexy of heart spleen (心脾俱中風), consumption of lung fluid caused by heat evil (肺津被灼), deficiency of lung energy (肺氣虛寒) and dificiency of kidney energy (腎虛). 5. The cause of seom-eo, kwang-eo, Jeong-seong were as follows ; the heart of stomach (胃中熱), the heat evil attach the blood chamber (血人血室) and the consumption of healthy energy (精氣奪). 6. In disorders of voice and speech, flaceid tong with aphasia (舌?) and aphasia due to throat disease (喉?) were divided.

각막굴절교정수술 후 안압하강의 보정에 관한 연구

정희재,박창원,김태훈,김효진 대한시과학회 2019 대한시과학회지 학술대회 Vol.2019 No.07

난시교정에 따른 광학적 질의 변화

정희재,박창원,김효진 대한시과학회 2020 대한시과학회지 학술대회 Vol.2020 No.01