혈액투석중인 만성신부전 환자에서 골대사 지표로써의 Osteocalcin치

송치운,이진홍,안미애,윤환중,윤상임,성기양,이강현,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Background : Serum osteocalcin is synthesized by osteoblast and has been shown to be sensitive indicator of bone turnover inpatients with various metabolic bone disease. In renal osteodystrophy, serum osteocalcin is elevated due to decreased renal clearance and elevated level of PTH. This study was done to evaluate the usefulness of serum osteocalcin as a marker of bone metabolism and the correlation with other biochemical markers of bone metabolism. Methods : We measured serum osteocalcin, calcium, phosphorus, ALP(alkaline phosphatase) and PTH(parathyroid hormone) in 37 patients with end stage renal disease on hemodialysis. Osteocalcin was determined by radioimmunoassay and PTH was determined by radioimmunometric assay. Results : 1) The mean level of serum osteocalcin in ESRD patients was 233.8± 218.2ng/ml which was significantly higher than that of controls(p<0.0001). 2) The mean level of serum PTH in ESRD patients was 40.5± 43.8pg/ml was significantly higher than that of controls(p<0.005). 3) There was a significant positive correlation between the level of serum PTH, ALP and the level of serum osteocalcin in ESRD patients. 4) By using multiple regression, PTH is most reliable factor that affect to elevated level of serum osteocalcin ( beta coefficient = 0.687, Sig T<0.05). Conclusion : Serum osteocalcin as a marker of bone metabolism in ESRD patients is more useful than other biochemical marker such as serum calcium, phosphorus, ALP and PTH is a most reliable factor that affect to elevated level of serum osteocalin.

옥수수·鷄糞 silage 製造時 formic, propionic acid 添加가 品質에 미치는 影響

宋瑛敏,金斗煥 진주산업대학교 농업기술연구소 1992 農業技術硏究所報 Vol.5 No.-

옥수수 silage의 영양가치 증진과 계분의 효율적이 처리방안으로 옥수수-계분 silage 제조시 formic acid 및 propionic acid첨가가 발효품질에 미치는 영향을 조사한 결과는 다음과 같다. 1. 재료의 성분중 옥수수에 많은 것은 조섬유, NFE, NDF, ADF였으며, 육계분에는 조단백질, 회분이 많이 함유되어 있었다. 2. Formic acid, propionic acid첨가로 옥수수-계분 silage의 화학적 조성에는 큰 변화가 없었다. 3. Propionic acid첨가구가 총질소함량에 대한 암모니아질소함량의 비율이 가장 낮아 품질이 우수한 것으로 나타났다. 4. Propionic acid첨가구가 pH가는 가장 낮았고, Total acid함량은 가장 많았으나, Flieg's평점은 산처리 하지 않은 옥수수-계분 silage보다 낮았다. 5. 총생균수, 유산균수 및 대장균수로 볼 때 formic acid나 propionic acid첨가로 다소 발효억제효과를 찾을수 있으나 뚜렷하지는 않았다. This experiment conducted to determine the effects of formic and propionic acid on the quality of the corn-manured silage. Admixing corn forage with broiler manure at 30% rate(DM basis)and formic or propionic acid was added at ensiling time at 0.5%, 0.75% rate(wet basis) respectively. Chemical composition, fermentation acids, pH, microbial population and distribution of the nitrogen contents were evaluated. The results obtained are summarized as follows; 1. Nutrients such as crude protein, crude ash were supplied from the broiler manure while crude fiber, NFE, NDF and ADF were supplied from the whole crop corn. 2. By adding the formic and propionic acid in the corn-manured silage, there was no marked difference in the general chemical compositions. 3. Production of ammonia nitrogen was the lowest in the propionic acid adding corn manured silage. 4. The pH value of the silage with propionic acid was the lowest, however total acid content was the highest. 5. Both total bacteria numbers and lactic acid bacteria being estimated as 10^6-10^7per g silage, were not significantly different among treatments.

도축돈 장분변으로부터 Shiga Toxin-Producing Escherichia coli의 분리와 성상

송영환,김지영,채미경,박창식,김명철,전무형 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Shiga toxin-producing Escherichia coli (STEC) causes various clinical signs in human and animals, and has been indicated as a global enteropathogen with zoonotic importance. In this study, the feces of healthy pigs were collected from the slaughtered pigs of Daejon abattoir during the period from December 2001 to October 2002. Of 326 specimens, 13 STEC were confirmed by culture, PCR and colony hybridization. The isolates were further studied for toxin types, pathogenic factors, plasmid profiles, and antimicrobial resistance to characterize the genetic and toxigenic properties. In PCR, all of 13 isolates were evident to have shiga toxin gene (stx). Of 13 isolates stx1 gene was detected in 4 and stx2 gene in 9. The genes of eaeA, hlyA and rfbE were not present in any isolates. In colony hybridization using shiga toxin common primer (STXc), 2 to 9 per 100 colonies subcultured from 13 isolates showed the positive reaction. In the examination for plasmid profiles of the isolates, one to eleven plasmids with varying sizes of 1.0 Kb to 100 Kb were detected, and the 13 STEC could be classified into four groups by the plasmid patterns. The antimicrobial resistance patterns of the isolates were comparably corresponded with the plasmid profile patterns.

소득작물 전후작지 적응 극단기성 벼 ‘중모 1032’

손영보,이종희,조준현,이지윤,오성환,송유천,박동수,박노봉,김상열,여운상,남민희,권영업 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

畜舍의 施設要因이 家畜의 福祉와 生産性에 미치는 影響에 관한 最近 硏究 動向

宋瑛敏,金斗煥 진주산업대학교 1991 論文集 Vol.29 No.-

가축의 생산성 증진을 위한 연구가 가축의 각종 환경분야로의 접근으로 지속되어 왔던바, 근래 가축의 복지향상을 통한 유전적인 잠재능력을 극대화하려는 노력들이 기울여지고 있다. 그러나 환경인자의 다양성과 작용기전의 복합성 및 측정방법의 비객관성으로 특정 환경인자의 독립적인 영향을 밝히기란 어려운 점이 많다. 가축의 복지와 생산성에 미치는 각종 환경요인의 영향에 대해서는 아직도 모호한 점이 많다. 그러나 궁극적으로 가축의 최적 생산환경 조성을 위한 모든 조치는 가축의 안락을 통한 생산활동의 지원에 있으므로 이 분야의 연구는 지속되어야 한다. 특히 인위적으로 가해지는 각종 환경요인의 영향이 규명되지 않고서는 관리기술의 진보를 기대하기는 어렵다고 할 것이다. 가축복지 분야의 최근 연구동향을 조사한 것으로 환경을 지배하는 시설요인이 가축의 생산성에 미치는 영향에 대해 여러 연구자들의 발표를 정리한 바 요약하면 다음과 같다. 1. 축군의 관리 측면에서 신체 일부분의 절단, 축군의 재배치와 혼합, 고립 혹은 격리 및 수송으로 인한 스트레스는 가축의 행동양식과 생산성에 크게 영향을 미치며, 각각의 효과는 축종에 따라 상반 될 수 있다. 2. 조기이유는 비정상정인 행동을 초래하며, 경우에 따라 장기적으로 영향하여 생산성을 저하시킬 수 있으며, 도살전 취급방법에 따라 육질에 영향을 미칠 수 있다. 3. 사육밀도 및 축군의 크기는 시설의 경제성과 관계가 매우 깊으며, 가축복지적 측면에서도 가장 중요한 요인이다. 4. 바닥면의 조건은 열환경을 지원하는 가장 중요한 인자일 뿐아니라 가축의 안락감에 가장 크게 영향하는 요인이다. 결론적으로 가축의 환경을 지배하는 모든 비기후적 인자가 생산성에 미치는 영향에 관한 연구는 활발하게 이루어지지 않았으나 앞으로 가축은 물론 관리자에게 안락감을 제공하여 최적 복지조건을 조성하고 생산성 향상을 도모해야 할 것이다. 특히 축사의 시설요인은 가축의 복지 및 행동습성과 밀접한 관계가 있으므로 시설요인에 의한 생산성을 저해하는 부정적인 영향을 제거하기 위하여 이 분야의 많은 연구가 요청된다. This review concentrated on recent studies published in the effect of housing conditions and manipulating husbandry systems on animal welfare and productivity. We should use the word "Welfare" in a scientific way so that may be useful when considering animal management or control of animal environment. When evaluating systems for housing conditions, manipulating factors and so on, we need precise measurements of how poor the welfare is. An accurate definition and measurement of both welfare and productivity is difficult. Since the measuring instruments are imprecise, any assessment of the correlation between welfare and productivity is often speculative. Notwithstanding these methodological problems a number of studies have indicated that some husbandry practices adversely affect both productivity and welfare. Further studies of animal welfare is required in relation to good welfare improving productivity.

전반적발달장애 아동 및 발달성언어장애 아동의 뇌 단일광자방출전산화단층촬영 소견에 대한 예비연구

이호분,신의진,육기환,유영훈,노경선,송동호 대한소아ㆍ청소년정신의학회 1997 소아청소년정신의학 Vol.8 No.2

증기발생기 세관에서 결함 선단 변화에 따른 와전류 결함신호의 분석

송성진,김의래,김창환,김영환 성균관대학교 기계기술연구소 2001 성균관대학교 논문집 기계기술편 Vol.4 No.1

Eddy current signals from flaws with tip variation in steam generator tubes were analyzed. Using finite element models, abundant flaw signals from two dimensional axisymmetric flaws will tip variation were generated. Features of ECT signal were defined and extracted, and sensitive features for flaw classification and sifting were selected. Two neural networks were employed for flaw characterization and sizing. The intercept vector was introduced as a new feature, and its usefulness was discussed.

저염농도의 자리발효식품의 가공에 관한 연구

송대진,김재하,강영주,김수현,고영환,하진환 濟州大學校 工科大學 産業技術硏究所 1990 産業技術硏究報告 Vol.1 No.-

This study was carried out to obtain the basic data on salted and fermented damsel fish(Jari-Jeot), one of the important traditional marine foods in Cheju-Do. and also to seek salt lowering method for the development of a new local tourist food. The results are as follows : The best organoleptic results were obtained after 60 days' fermentation for 25.0, 12.5 and 10% of salt-added group, and around 45 days for 7.5 and 5% of salt-added group. In raw fish ingredient IMP was abundant which marked 17.7 μmole/g while in fermented fish hypoxanthine was predominant but ATP and ADP were not detected after 30 days' fermentation. Sixteen kinds of free amino acids were detected and identified in Jari-Jeot instead of 17 kinds of those in raw sample. The abundant amino acids in Jari-Jeot after 60 days' fermentation were lysine. alanine, glutamic acid, glycine and leucine, and those were consisted of approximately 60% of the total free amino acids. During fermentation the content of TMAO was decreased gradually and no TMAO was detected after 75 days' fermentation while that of TMA was increased during fermentation up to 45 days' and decreased afterwards. The fatty acid of low-salt Jari-Jeot was composed of 31.9% of saturated acids, 13.2% of monoenoic acids and 54. 9% of of polyenoic acids. While the content of EPA in polyenoic acids was 1.9%, that of DHA was 23.0%. In order to lower salt concentaration of fermented damsel fish, additon of Pediococcus halophilus culture as a starter together with 10-12.596 of salt, 4-5% of KCI, and 2% of glucose gave as good quality as traditionally made Jari-Jeot.

성인의 적응장애

송지영,장환일 한국의학사 1986 診斷과治療 Vol.6 No.5

유방의 관상피내암종에서의 p27_kip1, Cyclin D1 및 p53 단백의 발현

오영륜,송상용,최종순,고영혜,이회정,안긍환 대한병리학회 1999 Journal of Pathology and Translational Medicine Vol.33 No.9