The Effects of Short-Term and Very Short-Term Particulate Matter Exposure on Asthma-Related Hospital Visits: National Health Insurance Data

송대진,최선희,송우정,박경희,지영구,조상헌,임대현 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.10

Purpose: The purpose of this study was to investigate the effects of short-term and very short-term exposure to particulate matter(PM) exceeding the daily average environmental standards for Korea (≤100 μg/m3 for PM10 and ≤50 μg/m3 for PM2.5) on on asthma-related hospital visits. Materials and Methods: This was a population-based, case-crossover study using National Health Insurance and air pollutiondata between January 1, 2014 and December 31, 2016. The event day was defined as a day when PM exceeded the daily averageenvironmental standard (short-term exposure) or daily average environmental standard for 2 hours (very short-term exposure). The control day was defined as the same day of the week at 1 week prior to the event day. Results: Compared with control days, asthma-related hospital visits on the 24-hr event days and 2-hr event days increased by4.10% and 3.45% for PM10 and 5.66% and 3.74% for PM2.5, respectively. Asthma-related hospital visits increased from the 24-hrevent day for PM10 to 4 days after the event day, peaking on the third day after the event day (1.26, 95% confidence interval, 1.22–1.30). Hospitalizations also increased on the third day after the event. While there was a difference in magnitude, PM2.5 exposureshowed similar trends to PM10 exposure. Conclusion: We found a significant association between short-term and very short-term PM exposure exceeding the current dailyaverage environmental standards of Korea and asthma-related hospital visits. These results are expected to aid in establishingappropriate environmental standards and relevant policies for PM.

기관지천식에 관한 인터넷 정보 : 현황과 그 개선방향

송대진,김형진,홍승희,정지태 대한천식알레르기학회 2004 천식 및 알레르기 Vol.24 No.2

Background: Recent advances in the Internet have enabled patient to search for large amounts of medical information. The Internet is easily accessible, but available information is under no guidelines or regulations in Korea. Objective: We evaluated the quality of information related to bronchial asthma on the Internet and the role in patient education with simple search technique. Method: The search phrases “bronchial asthma” were entered into four common Internet search engines. As indicated by the search engines, web sites and the 50 most commonly encountered web documents were reviewed. An information score (IS) from Libertiny et al. was modified to assess how well the web page educated the patient about the disease. Result: Of 110 web sites and documents, 109 were accessible. 41 (37.6%) web sites and documents were pub lished by private practice groups. The overall mean information score was 3.606, and only 10 (9.2%) sites had useful patient-oriented information (IS>10). Differences in IS between 8 subgroups were not significant (P=0.075). Misleading or unconventional therapeutic recommendations were recognized in 11 (10.1%) and 24 (22%) sites, respectively. Conclusion: Patient-oriented bronchial asthma information is difficult to find on the Internet in Korea. The overall quality is poor. About one third presented information that was classified as misleading or unconventional, especially in oriental medicine sites. There is an urgent need to develop proper asthma patient educational programs, guidelines for medical web site evaluation and gateways to high quality Internet-based medical resources.

빅데이터 기반 STEAM 융합 교육

송대진 대한산업공학회 2015 ie 매거진 Vol.22 No.2

전복의 동결에 관한 연구 1. 동결속도가 전복품질에 미치는 영향

송대진,SONG Dae-Jin 한국수산과학회 1973 한국수산과학회지 Vol.6 No.3,4

생 전복을 액체질소동결, 송풍동결, 반송풍동결, 정지공기동결의 네가지 동결방법으로 동결하여 $-20^{\circ}C$에서 3개월간 저장하여 동결방법에 의한 전복근육의 물성적 변화, 단백질의 변성 등을 검토하여 다음과 같은 결과를 얻었다. 1) 생전복의 사후경직은 다른 어류보다 빨랐다. 2) 압측시험치, 전단시험치는 액체질소동결을 제외하고는 동결방법에 의한 차는 없었고, 저장기간이 길어짐에 따라 약간 감소하였다. 3) 염가용성질소는 동결저장기간중 용출량이 완만하게 감소하였다. 4) 유리수의 유출량은 패주와 다리 사이에는 차가 있었고, 저장기간중 패주는 유리수가 증가하는 경향이었다. 5) Texture의 Panel test 결과 저장기간을 통하여 Texture가 감소하는 경향이었으며, Texture의 변화는 유리수의 변화(P<0.01), 단백질의 변성(P<0.05), 압축시험치의 변화(P<0.05)와 유의의 상관관계가 있었다. 본 논문을 지도하여 주신 동경수산대학 교수 전중 화부 박사 그리고 논문의 작성에 조언해 주신 부산 수산대학 식품공학과 이응호 박사님께 감사의 뜻을 표한다. To study the effect of freezing rate on the duality of frozen abalone(Haliotis gigantea, GMELIN) liquid nitrogen spray freezing, air blast freezing, semi-air blast freezing, and still air freezing were carried out. The rheological change, protein denaturation, and free water content of frozen and thawed abalone were examined at the period of 0, 1, 2, and 3 month during cold Storage at $-20^{\circ}C$. The results are summarized as follows : 1. The onset and duration of rigor mortis of fresh abalone was faster and shorter as compared to that of fishes. 2. There was no difference in compression value and shear value between freezing methods but they varied with a slight decrease in storage period. 3. Gradual decrease in extractibility of salt soluble protein was observed in all samples except those frozen with liquid nitrogen. 4. The free water of the foot muscle remained constant during the storage while that of the adductor muscle tended to increase. 5. A significant correlation was observed among the changes of panel texture and free water (P< 0.01), protein denaturation (P<0.05), and compression value (P<0.01).

Studies on processing and storage of eel, Anguilla japonica 1.Changes in free amino acids during processing : 제1보. 가공중의 유리아미노산의 변화

송대진,하진환,이응호 제주대학교 해양연구소 1982 해양자원연구소연구보고 Vol.6 No.-

Some Numerical Cases of Entanglement Concentration Using Entanglement Swapping

송대진 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.5

The quantum information network is important in establishing next-generation technology. In particular, maximal and long-distance entangled states are important in realizing a number of quantum information technologies, such as teleportation, key distribution and so forth. Entanglement swapping is a scheme that creates a long-distance network by using multiple short ones. Entanglement swapping protocols applied to non-maximal correlations have been thoroughly investigated by various people. Rather than providing any new analytic results, some examples of a numerical approach will be provided in this paper. In particular, the paper reveals the existence of different classes of coefficients that approximate the optimal outcome ({\it i.e.}, the weaker average maximal entanglement between the two initial states). The new class of states is non-trivial in the sense that their coefficients are just as widely distributed as the coefficients of states satisfying optimality conditions are. Moreover, we will numerically examine entanglement swapping methods and show the distribution of optimal and general coefficients for three and four 2-level correlations.

적색근어류와 백색근어류의 조직화학적 연구

송대진 제주대학교 해양연구소 1981 해양자원연구소연구보고 Vol.5 No.-

As a survey of changes by freezing for red muscle fishes yellow tail(Seriola quinqueudiutu), mackerel (Scomber japonicus), horse markerel(Trachurus japonicus)-and white muscle fishes-yellow corvenia (Pseudosciaena manchuria), cutlass fish(Trichiurus lepturus), harvest fish(Pampus argenteus), microscopic test for homogenate were carried out. In the difference of microscopic external shape of muscle fiber between these two groups, white muscle fishes were thick and short while red muscle fishes are thin and long. In the fresh muscle homogenate, yellow corvenia was fragmented to myofibril level and intermixed as thread while mackerel was also fragmented to myofibril level, but it was cut into tiny pieces. Muscle homogenate after one month freezing storage showed either cohesion or loss of elasticity. This phenomena were more apparent in white muscle fishes than red muscle fishes.

KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea

송대진,송우정,권재우,김건우,김미애,김미영,김민혜,김상하,김상헌,김상혁,김선태,김세훈,김자경,김주희,김현정,김효빈,박경희,윤재균,이병재,이승은,이영목,이용주,임경환,전유훈,조은정,지영구,진현정,최선희,허규영,조상헌,김상훈,임대현 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.6

Chronic cough is common in the community and causes significant morbidity. Severalfactors may underlie this problem, but comorbid conditions located at sensory nerve endingsthat regulate the cough reflex, including rhinitis, rhinosinusitis, asthma, eosinophilicbronchitis, and gastroesophageal reflux disease, are considered important. However, chroniccough is frequently non-specific and accompanied by not easily identifiable causes during theinitial evaluation. Therefore, there are unmet needs for developing empirical treatment andpractical diagnostic approaches that can be applied in primary clinics. Meanwhile, in referralclinics, a considerable proportion of adult patients with chronic cough are unexplained orrefractory to conventional treatment. The present clinical practice guidelines aim to addressmajor clinical questions regarding empirical treatment, practical diagnostic tools for nonspecificchronic cough, and available therapeutic options for chronic wet cough in childrenand unexplained chronic cough in adults in Korea.

「개불」의 식품학적 연구 (Ⅱ) : 유리 유기산 및 betaine에 관하여

송대진 제주대학교 1969 논문집 Vol.1 No.-

개불의 유리 betaine 및 유기산의 실험결과를 요약하면, 1) 유리 betaine의 함량은 패류와 거의 비슷하며 총 질소의 10.2%를 차지하였다. 2) 유기산의 검출 결과 lactic, succinic, malonic, citric, fumaric, 등을 검출 하였으며 lactic, succinic acid의 Spot는 현저 하였다. 3) 유리 betaine 및 유기산, 아미노산 등의 병합된 맛이 개불의 독특한 풍미를 이룬다 볼 수 있다. 「Kae-Bul」(urechis unicintus) which is caught in the Southern coastal area of Korea from October through early spring of next year has been highly esteemed for its characteristic taste as one of the tasty food stuffs for raw fish or stew. Free organic acid and betaine were analysed as a component responsible for the taste. As a result, the following were attained. 1. Lactic acid, succinic acid, malonic acid, fumaric acid, citric acid, and two unknown chromatgram were detected by paper partition chromatography and succinic acid, lactic acid were dominant. 2. The amount of betaine was similar to that in shell fish, and it was 10.2% of Extractive Nitrogen. 3. The characteristic taste of Kae Bul can be attributed to the intermixed components such as organic acid, betaine, and Amino Acid.

소라의 식품학적 특성

송대진,김효선,하진환 濟州大學校 産業技術硏究所 2000 산업기술연구소논문집 Vol.11 No.2

Characteristics of turban shell Batillus cornutus. as a food component was investigated to establish the data. to use more effectively. Proline. glutamic acid. taurine and glycine were abundant in raw turban shell and those were consisted of 55.1% of the total amino acids. IMP and inosine were dominant in raw while those were decreased significantly during canning. Succinic acid. pyroglutamic acid and malic acid were abundant in raw and canned ingredients while the contents were decreased notably during canning. The polyenic acid such as arachidonic acid and EPA were abundant and followed by saturates and monoenes. in that order. Na. Mg. K and Ca were predominant in raw turban shell while those contents were decreased considerably during canning.