당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

Rifampicin에 의한 것으로 추정되는 위막성 대장염1예

김수현,이은우,정종혁,문승현,김동한,양혁승,오영상,김호동,김도현,박혁,박정환,박경옥,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Pseudomembranous colitis, caused by altering the normal colonic flora and allowing the multiplication of Clostridium difficile, is an deleterious adverse effect of antibiotics. But it is rarely reported by rifampicin. Rifampicin is one of the first line drug in the treatment of tuberculosis and many patients are exposed to its potential adverse effects. We experienced a patient that had abdominal discomfort and hematochezia due to pseudomembranous colitis after receiving antituberculous medication, and which was probably caused by rifampicin. A 82 years old man was admitted with abdominal discomfort and hematochezia for one week. On the past history he had been diagnosed as endobronchial tuberculosis about 4 months ago. Colonoscopy revealed multiple discrete whitish mucosal lesion on rectosigmoid colon, and histologic findings were consistent with pseudomembranous colitis. The antituberculous agents were discontinued and vancomycin was administered. The patient's symptoms were resolved within several days. There was no recurrence after reinstitution of the antituberculous agents excluding rifampicin. We report here on a case of pseudomembranous colitis probably due to rifampicin.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

産卵初期飼料의 給與時期가 經濟性에 미치는 影響

文勝式,朴成振,宋瑛敏 진주산업대학교 1984 論文集 Vol.22 No.-

This experiment was conducted to investigate effects of feeding time of laying stater A(17 weeks of age), B(19 weeks of age), C(21weeks of age) and D(23 weeks of age) on egg production, average egg weight, first egg day, firet egg body weight, first egg weight and feed comsumed with a total of 120 pieces pullet grower(Babcock B380) during the experimental period of 98 days from August 30, 1984. December 12, the same year at poultry farm Jinju Agricultural and Forestry Junior Technical College. The results obtained were summarized as follows: 1. Hen­day egg production (19­32 weeks of age) was 1435 (C), 1405 (B) 1391 (A) and 1386(D) in order and there were nonsignificant(P>0.05) difference between all the plot. 2. Average egg weight(19­32 weeks of age) (g) was heavy in the order of D(57.23±4.17), C(56.17±3.76), B(55.53±3.9) and A(55.37±3.59) and egg weight at first laying (g) was heavy in the order of D(53.02±2.29), C(52.04±2.93). B(51.04±2.10) and A(50.82±2.42)(P>0.05) 3. The average day at first laying was long in the order of D(176.9±20), A(173.9±22), C(173.3±25) and B(173.1±23) (p>0.05) 4. The average body weight at first laying(g) was heavy in the order of A(2084.2±17.3), B(2075.8±133), C(2031.1±135) and D(2019.7±127) and the average body weight at32weeks of age (g) was heavy in the order of A(2505±102), B(2501±86), C(2485±123) and D(2483±111)(P>0.05). 5. The average feed comsumed (17­32 weeks of age) (g) was superior in the order of D(11767), C(11867), A(12100) and B(12167) (p>0.05) 6. In the economical analysis, egg producting cost per ㎏(won) was low in the order of D(918.93), C(918.72), B(980.63) and A(955.40)

닭의 乾燥 筋胃粘膜 粉末 投與가 Egg Type Fowl에 미치는 效果에 對한 硏究 : 第Ⅰ報 增體 및 羽毛量에 미치는 影響에 關하여 Ⅰ. The effect of body weight gainand feather weight

文勝式,朴玉潤 진주산업대학교 1981 論文集 Vol.19 No.-

This experiment was conducted to investigate the effect of Fowl Gizzard Mucouse Membrane Power treatment on body weight gain and feather weight with the data obtained from 60 pieces egg type fowls Babcock (B 380, 24 days-age) fed and allotted 4 treatments at the rate of 0%(C), 1%(T_1), 2%(T_2) and 3%(T_3) of FGM during the experimental period of 56 days from September 17, 1981 to December 12, the same year at Department of Animal Science, Jin Ju Agricultural and Forestry Junior Technical College. The results obtained are summarized as follows: 1. Average body weight gain at each experimental plot was 847.63g(T_2), 842.07(T_1), 828.94(T_3) and 815.83(C). The effect of FGM in the cody weight gain was nonsignificant for all the experimental plots. Feed conversion at each experimental plot was 3.65(T_2), 3.67(T_1), 3.75(C) and 3.77(T_3). 2. Average feather weight at each experimental plot was 105.84±10.13g(T_3), 90.78±13.55(T_2), 89.06±4.66(T_1) and 88.06±7.55(C). The effect of FGM in the only feather weight of T_3 plot was significant(p<.0.01).

정상성인의 외측대퇴피부신경 체감각 유발전위 검사

문성식,박미영 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

Background: Meralgia paresthetica(MP) which is characterized by paresthesias and sensory impairment without motor weakness in the anterolateral aspects of the thigh is produced by compression of the lateral femoral cutaneous nerve(LFCN). Even though the diagnosis of MP is mostly based on the clinical symptoms, electrophysiologic study is mandatory to confirm the disease objectively. It has been known that Somatosensory evoked potential(SSEP) study of LFCN is a simple and very useful method to evaluate MP, so we studied SSEP of LFCN in normal adults and offer normal values. Materials and Methods: Thirty six normal adults(23 males and 13 females) ages from 21 to 73 years old(mean±SD:42.06±15.74) were studied SSEP of LFCN bilaterally. The stimulation site was anterolateral aspect of thighs and the recording site was Cz'. Results : The mean values(msec±SD) of LP0, SP0, LN1 and SN1 of all subjects were 35.10(±2.42), 33.80(±2.4), 43.68(±1.88) and 42.16(±2.12) and the mean values(msec±SD) of DP0, DN1 and DA(μV±SD) were 1.30(±1.14),1.52(±1.38) and 0.32(±0.33). Conclusion: For the diagnosis of MP, comparison of latency difference between both sides is more reliable than simple value of latency itself because of individual differences of body types. According to our results, the latency difference should be less than 2 msec and the amplitude difference was less than 1.6 times in normal adults.

艾葉粉末의 添加給與가 肉鷄에 미치는 影響

文勝式,朴玉潤,宋瑛敏 진주산업대학교 1985 論文集 Vol.23 No.-

本 試驗은 1985년 9월 20일 孵化된 肉鷄用(Hubbard) 병아리 120首를 各區當 30首씩 4개區로 나누어 晋州農林 專門大學 養鷄場에서 3주간(1985.10.19~11.8)에 걸쳐 艾葉을 C(0%), T_1(1%), T_2(2%), T_3(3%)水準으로 飼料에 添加하여 給與試驗을 하였던 바 다음과 같은 성적을 얻었기에 報告하는 바이다. 1. 增體量은 T_1區(1296.32g), C區(1274.70g), T_3區(1264.32g) 및 T_2區(1259.64g)의 순으로 나타났다(p>0.05). 2. 飼料攝取量은 C區(2715. 13g), T_1區(2738.60g), T_2區(2754.16g) 및 T_3區(2811.46g)의 순으로 나타났고 飼料要求率은 T_1區(2.113), C區(2.130), T_2區(2.178) 및 T_3區(2.232)의 순으로 나타났다(p>0.05). 3. 産肉指數는 T_1區(306.48), C區(303.01), T_2區(293.38) 및 T_3區(284.86)의 순으로 나타났다. 4. 屠體率은 ♀는 T_1區(69.45), T_2區(69.30), T_3區(67.58) 및 C區(66.45)의 순이였고 ♂은 T_3(70.03), T_2區(69.13), T_1區(67.85) 및 C區(66.58)의 순이였다. 5. 臟器重量은 대조구와 처리구간에 차이를 볼 수 없었다. 6. 經濟性을 분석한 結果 各 區別 수당수익은 T_1區(613원), C區(590원), T_2區(583원) 및 T_3區(572원)의 순으로 나타났다. This experiment was all located to 4 plots by 30 chickens per each plot with 120 chickens of broiler-Hubbard hatched at the 20th of September, 1985 and the formula feed added in the levels of 0(C plot), 1(T_1 plot), 2(T_2 plot) and 3%(T_3 plot) of Artemisia was supplied for these of each plot during 3 weeks from October, 19 to November, 8, 1985 at the poultry house, Chinju Agricultral & Forestry Technical College. The results found out the effect of Artemisia meal addition on the growth of broiler-Hubbard were as follows: 1. The weight gain(g) was heavy in the order of T_1(1296.32), C(1274.70), T_2(1264.32) and T_3(1259.64) and non significant (p>0.05) between plots. 2. Feed consumption(g) was heavy in the order of C(2715. 13), T_1(2738.6), T_2(2754.16) and T_3(2811.46) and feed conversion, T_1(2.113), C(2.130), T_2(2.178) and T_3(2.232) (p>0.05). 3. Point spread was high in the order of T_1(306.48), C(303.01), T_2(292.38) and T_3(284.86). 4. Dressing percent of female ws high in the order of T_1(69.45), T_2(69.30), T_3(67.58) and C(66.45), and of male, T_3(70.03), T_2(69.13), T_1(67.85) and C(66.58). It was generally higher in the Artemisia meal addition plot than in the control. 5. Internal organies weight was non significant differences(p>0.05) between treatment plots and control. 6. In economical analysis, net income(won) per bird of each plot was 613(T_1), 590(C), 583(T_2) and 572(T_3).

Lactobacillus plantarum을 接種한 옥수수와 수수 Silage 製造 試驗

文勝式,朴成振,鄭錫龍,宋瑛敏 진주산업대학교 농업기술연구소 1989 農業技術硏究所報 Vol.2 No.-

유산균 접종이 옥수수와 수수silage의 품질에 미치는 영향을 조사할 목적으로 L. plantarum을 대조구는 접종하지 않았고 처리구는 2×10 exp(8), 4×10 exp(8) 및 6×10 exp(8)cfu, kg^-1(fresh forage) 수준으로 접종하여 조제한 silage의 일반성분, pH 및 유기산 함량을 비교한 결과는 다음과 같다. 1. crude protein, crude ash, NDF, ADF 및 hemicellulose 함량은 접종수준이 증가할수록 높았고 moisture 및 NFE 함량은 낮았다. 2. 접종수준이 증가할수록 lactic acid와 total acid 함량은 증가한 반면 acetic acid함량과 pH는 낮았다. 3. 옥수수 silage에 비하여 수수silage에서 L. plantarum의 접종효과가 높았다. The objective of this thesis is to investigate the effects of lactic acid bacterium inoculation on the qualities of corn and sorghum silages. The control group was not inoculated : the treated group was inoculated with Lactobacillus plantarum of the levels of 2×10 exp (8), 4×10 exp(8) and 6×10 exp(8) cfu. Kg^-1(fresh forage). The chemical components, pH and organic acid contents of the developed silages were measured and compared. The results obtained are as follows : 1. As the level of inoculation was higher, the contents of crude protein, crude ash, NDF, ADF and hemicellulose became larger, but the contents of moisture and NFE became smaller. 2. As the level of inoculation was higher, the contents of lactic acid and total acid became larger, but the acetic acid content and the pH became smaller. 3. The inoculation effect of L. plantarum was greater in the sorghum silage than in the corn silage.

産卵鷄에 대한 練炭灰添加給與 效果에 關한 硏究

朴成振,文勝式,鄭場龍 진주산업대학교 1982 論文集 Vol.20 No.-

This experiment was conducted to investigate the effect of Briquette ash treatment on egg production rate, egg weight, feed conversion and egg quality with date obtained from 100 pieces egg type fowls Babcock (B 380, 230days-age) fed and allotted 5 treatments at the rate of 0%(C), 0.5%(T_1) 1.0%(T_2), 1.5%(T_3)AND 2.0%(T_4) during the experiment period of 119 days from May 21, 1982 to September 20, the same year ar Department of Animal science, Jin Ju Agricultural and Forestry Junior Technical College. The results obtained are summarized as follows; 1. Average egg weight at each experiment plot was 62.21g(T_2) 61.62g(T_3), 60.88g(T_4), 60.42(T_1) and 60.04g(C), but the difference was not significant. Feed conversion at each experiment plot was 2.52(T_2) 2.60(T_3), 2.65(C) and 2.67(T_4). 2. Average egg production rate at each experiment plot was 82.02%(T_2) 81.85%(C) 81.43%(C), 79.41%(T_3) and 78.23(T_4), but the difference was not significant. 3. Weight of egg yolk and albumen were higher at fed with the treated Briquette ash plot than that without Briquette ash plot, and weight of egg shell and thickness were not significant.

糖蜜吸着 煉炭灰飼料의 添加가 肉鷄의 發育에 미치는 影響

朴成振,文勝式,宋瑛敏 진주산업대학교 1989 論文集 Vol.27 No.-

본 시험은 육용계(Arbor acres) 160수를 공시하여 당밀 흡착연탄재사료(Molasses-absorbed briquette ash feed : MBF)를 육계사료에 0, 2, 4 및 6% 수준으로 첨가하였을 때 사양성적, 도체율, 복강지방, 소화기관, 계분의 수분과 회분 및 경제성 등에 미치는 영향을 조사하기 위하여 실시하였다. 1. 종료시 체중과 증체량은 MBF첨가에 의해 개선되었고 그 경향은 2% 및 4% 구에서 크게 나타났다(P<0.05). 2. 사료효율은 2%구에서 가장 좋은 경향이었고 2%구와 6%구를 제외한 다른 구에서는 차이가 없었다(P>0.05) 3. 도체율과 복강지방은 각구에서 큰 차이가 없었다. 4. 소화기관의 중량 및 길이는 각구에서 큰 차이가 없었다. 5. 계분의 수분함량은 각구에서 비슷하였으나 회분함량은 첨가 수준이 높을수록 증가되었다. 6. 경제성 분석 결과는 2% 및 4%에서 양호한 편이었다. This experiment was performed to study the effects of addition levels 0, 2, 4 and 6% of molasses-absorbed briquette ash feed(MBF) on 180 broilers. On the growth, dressing percentage, abdominal fat, gastrointestinal tract, moisture and ash content in excreta and economics were investigated. The results are summarized as follows : 1. Final weight and weight gain were significantly higher in MBF added 2% and 4% group(P<0.05) 2. Feed efficiency was significantly(P<0.05) higher in 2% group and was not differences between other expect 2%, 6% group. 3. Dressing percentage and abdominal fat was not significantly each group. 4. Gastrointestinal tract weight and length was not significantly each group. 5. Moisture contents in excreta were didn't show significant differences between the each treatment group, but ash contents in excreta increases according to the increasing level of MBF. 6. Optimun level of maximum profit on economic analysis was found to be 2% and 4% group with broiler chicks.