Cellulose Triacetate 막에서 CD₂ 와 CH₄혼합기체의 투과

배성렬,노상호,이규훈 한양대학교 에너지 ·환경기술연구소 1995 에너지·環境技術論文集 Vol.2 No.-

Cellulose Triacetate막에서 CO₂의 수착실험은 pressure decay method에 의해서 행하였고, 수착실험의 온도범위는 50℃, 60℃이고 압력범위는 13atm 까지 가압하여 수착 등온선을 측정하였다. 이런 조건하에서는 CO₂의 수착평형은 Dual-mode sorption model에 의한 이론치와 실험치가 비교적 일치한다는 것을 알 수 있다. Dual-mode sorption model 수착 매개 변수들은 비선형 최소 자승법으로 구하였다. 투과실험은 같은 온도 조건과 25atm까지의 압력 범위까지 수행하였다. 실험에서 얻은 평균투과계수의 압력의존성은 고온, 고압에서 기존의 Dual-mode mobility model로는 설명할 수 없었다. 이런 현상은 기체 분자에 의한 가소화 현상 때문으로 생각할 수 있다. 따라서 modified dual-mode mobility model을 적용시킨 결과 잘 일치하였다. 또한 CTA막에서 CO₂와 CH₄혼합기체의 투과 실험을 40℃, 50℃, 60℃의 온도 범위와 25 atm의 압력 범위 하에서 행하였다. 순수 기체에 비해서 복잡한 혼합 기체의 투과를 설명하기 위해서 Dual-mode mobility model을 적용시켜 보았고 잘 일치하는 것을 알 수 있었다. 또한 혼합 기체의 거동에서 CO₂을 고려한 부분투과계수를 구하였다. 이때의 부분투과계수의 압력 의존성이 Dual-mode mobility model에 잘 일치하는 것을 알 수 있었다. The sorption isotherms of CO₂in cellulose triacetate membrane sample were measured by a pressure decay method to examine the sorption model of CO₂. And the permeation experiments were perfomed by variable volume method to analyze the permeation model of CO₂. Sorption experiments carried out 50, 60℃ and pressure up to 13 atm in cellulose triacetate. The sorption equilibria of CO₂at these temperature range can be simulated well by dual-mode sorption model. The values of the dual-mode sorption parameter were estimated by the non linear least square method. Permeation runs were carried out at same trmperature and pressure to 25atm. The pressure dependence of mean permeability of CO₂at these temperature range couldn't accurately be simulated by a dual-mode mobility model because of the plasticization action of sorbed gas in the polymer membrane. But more satisfactorily simulated by a modified dual-mode mobility model. An analytical solution has been obtained for the dual-mode mobility model extended to a binary gas mixtures to describe the pressure dependence of mean permeablity for CO₂and CH₄in the cellulose triacetate membranes. Binary gas of permeation rate measured at 40, 50, 60℃ and upstream pressure 25atm. Mean permeability of each component in a binary gas were calculated by the basis of the dual-mode mobility model.

재가 의료보호대상 정신질환자의 특성에 대한 조사 : 서울특별시 7개 보건소 등록 환자를 대상으로

이주훈,오석배,박종원,지성학,장화순 용인정신의학연구소 1994 용인정신의학보 Vol.1 No.2

紡絲工程에서의 Emulsion Fume 處理를 위한 充塡塔 適用에 관한 硏究

최동훈,박진식,장성호,김일배,서정민,김장호 동아대학교 환경문제연구소 1996 硏究報告 Vol.19 No.2

This study was carried out to interpret hydraulic behavior and component analysis of the emulsion fume, laboratory work of mass transfer in the packing tower which packed 50mm plastic Hiflow-ring. The results from experiment are as follows : 1. The component of emulsion fume is Cyclododecane, 1-Tridecene, 4-Nonene 5-butyl. The kinds of Alkene contained approxymately 76.23 percent. 2. To compare with conventional packing, 50mm Hiflow-ring could save energy because of low pressure drop under high load. 3. The unique magnituteds of packing witch was used are as follows. Cv = 5.18 × 10^(-4) , m = 0.683, n=0.462 so we can predict efficiency which occurres. 4. To require plant of the packing tower in the gas capacity factor 2.7 (Kg^(1/2) m^(-1/2) s^(1))

조형된 연골막판을 사용한 이개재건에 대한 실험적 연구

김성수,배용찬,정성훈,김석권 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.4

Although carved cartilage grafts from rib are commonly used for ear reconstruction, it is difficult to mimic a normal pinna and these reconstructions are so firm and unnatural. Therefore, we had a basic experimental study for a new technique of ear reconstruction. We tried to creat a cartilage framework by moulding the perichondrial flap experimentally. The perichondrial flap with the vascular pedicle of the central vessels was elevated in rabbit ear and placed between the leaves of a silastic mould. This preparation was placed in a pocket under adjacent scalp and sic and eight weeks later the preparations was harvested and assessed gross and histological findings. The moulded perichondrial flap was well developed and a thin cartilage layer was recognized within the convolutions created by the mould. Grossly, it was not so firm but relatively soft and there was little difference between at six and eight weeks. Histologically, viable new chondrocytes and active cartilage formation were demonstrated in the perichondrium at both six and eight weeks. The moulded cartilage which was harvested after 6 weeks was irregular in thickness and it's chondrocytes were not completely developed. However, the cartilage which was harvested after eight weeks was relatively regular in thickness and it's cells, especially centrally located, were fully developed. Clinically, ear reconstructive may be completed by implantation of this moulded cartilage as traditional reconstructive method. Otherwise, this moulded cartilage can be harvested with its vascular pedicle and the pedicle can be anastomosed with superficial temporal artery. And then a split thickness skin graft on the perichondrium enveloping the moulded cartilage or covering with skin flap which was expanded with tissue expander may complete the ear reconstruction in single stage operation. If further investigations for materials of the mould, optimal period for maximum cartilage synthesis and durability of moulded cartilage are studied, this moulded perichondrial flap technique provides the potential advantage of ear reconstructions.

사지의 주요 동맥손상의 처치: 23증례에 대한 분석

원형섭,김상은,배성만,박철완,이 근,조상훈,김상일,우병완 大韓應急醫學會 1996 대한응급의학회지 Vol.7 No.1

Extremity vascular trauma is common in most emergency centers, and controversy remains about the optimal management of arterial injuries. Retrospectively we reviewed the records of 23 patients who had upper or lower extremity arterial trauma from July 1994 to December 1995. The purpose of this study was to evaluate our department`s management policy to major arterial injuries. The leading cause of major arterial injuries was penetrating trauma. We found that there were clinical findings such as absence of or decreased strength of pulsation(82.6%), cool ischemic extremity(69.6%), large expanding hematoma(43.5%), major bleeding(17.4%) and bruit or thill(8.7%). We gave the priority to management of life-threatening injuries and applied the pressure dressing to wounds as early as possible. There were 18 men(78.3%) and 5 women(21.7%); the mean age was 35(range 20-56 years old) years. There were 12 arterial injuries(52.2%) in the upper extremity and 11 arterial injuries(47.8%) in the lower exteremity. The most commonly injured artery was the brachial artery in the upper(34.8%) and the femoral artery in the lower(30.4%) extremity. The etiology included knife stabbing in 10 patients(43.5%), motor vehicle accidents in 6(26.1%), industrial accidents in 4(17.4%), falls in 2(8.7%) and a farm equipment accident in 1 patient(4.3%). The associated injuries were muscle injuries(78.3%), fracture(56.5%), nerve injuries(52.2%), vein injuries(43.5%), shock(17.4%) and dislocation(13.0%). All patients with arterial injuries were given a preoperative prophylactic antibiotic and TIG(tetanus immunoglobulin). We used Doppler technique as a means of detecting the blood flow. Fourteen patients(60.9%) underwent preoperative arteriography in the radiology department. We performed surgical exploration as soon as major arterial injuries were suspected. The most common methods of treating major arterial injuries were interposition vein graft(69.6%) and end to end anastomosis(21.7%). Systemic or locally infused heparin was used for all vascular repairs. In many of our patients(56.5%), fasciotomy was performed before the vascular repair, as a part of the exploration of the distal arteries. There were 2 amputations(8.7%) but no death. The reason for secondary amputation were wound infection in one and failure to achieve sufficient arterial flow to the involved extremity with resulting gangrene in the other. As the time factor is vitally important in the management of arterial injuries, we advocate prompt and early surgical treatment within 6 hours of the trauma. In conclusion, we believe that the crucial factorsin successful management of major arterial injuries of the extremities are early diagnosis, prompt treatment, complete debridement, fasciotomy when indicated, and simultaneous treatment of concomitant injuries.

Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예

백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy

인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화

신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.

Feasibility of Speech Testing Using Wireless Connection in Single-Sided Cochlear Implant Users

Bae Seong Hoon,Jung Youngrak,Hur Ji Hye,Kim Jeong Ha,Choi Jae Young 대한청각학회 2023 Journal of Audiology & Otology Vol.27 No.3

Background and Objectives: The speech tests used to evaluate language performance in patients with bilateral deafness (BiD) and cochlear implant (CI) are problematic if applied to patients with single-sided deafness (SSD) because normal ear hearing should be excluded. Thus, we investigated the feasibility of using wireless connection to evaluate speech intelligibility of the CI ear in patients with SSD.Subjects and Methods: Patients with BiD and SSD were administered the word recognition scores (WRS) and speech intelligibility tests using an iPadbased wireless connection and conventional methods. To exclude normal side hearing in patients with SSD, masking noise and “plugged and muffed” method were used in the WRS and speech intelligibility tests, respectively.Results: In patients with BiD, the WRS and speech intelligibility tests results using wireless connection and conventional methods were similar. In patients with SSD, the WRS using masking noise in the normal hearing ear was similar to that of using wireless connection. However, 3 of 11 patients with SSD showed under-masked results if using the “plugged and muffed” method.Conclusions: Speech intelligibility testing using wireless connection is a convenient and reliable method for evaluating CI performance in patients with SSD. The “plugged and muffed” method is not recommended for evaluating CI performance in patients with SSD.

Adequacy of sentinel lymph node biopsy in malignant melanoma of the trunk and extremities: Clinical observations regarding prognosis

Bae, Yong Chan,Jeong, Dae Kyun,Kim, Kyoung Hoon,Nam, Kyung Wook,Kim, Geon Woo,Kim, Hoon Soo,Nam, Su Bong,Bae, Seong Hwan Korean Society of Plastic and Reconstructive Surge 2020 Archives of Plastic Surgery Vol.47 No.1

Background Methods for identifying local lymph node metastasis in malignant melanoma include sentinel lymph node biopsy (SLNB) and lymph node dissection (LND). In particular, SLNB has been widely used in recent years. This study aimed to retrospectively confirm the adequacy of the current indication criteria for SLNB by applying those criteria to a mixed group of patients who previously received SLNB and LND. Methods This study included 77 patients with malignant melanoma of the extremities and trunk who were monitored for >24 months. The patients were classified according to whether the current indication criteria for SLNB were applicable. The sentinel lymph nodes were evaluated for each group. Patients for whom the indication criteria for SLNB and LND were applicable were analyzed according to whether SLNB or LND was performed. Finally, the outpatient records of these patients were reviewed to evaluate recurrence, metastasis, and prognosis. Results Of the 77 patients, SLNB was indicated according to the current criteria in 60 cases. Among the 60 patients for whom SLNB was indicated, 35 survived the follow-up period disease-free, 21 died during the follow-up period, and four experienced metastasis. The 17 patients for whom SLNB was not indicated had no recurrence or metastasis. Conclusions Patients for whom SLNB was not indicated had no recurrence or metastasis. In cases where SLNB is indicated, the possibility of metastasis and recurrence may be high even if SLNB is negative or LND is performed, so more aggressive treatment and careful follow-up are crucial.

플립드 러닝과 프로젝트 기반 학습을 결합한 메타버스 게임화 교수법이 대학생의 과제가치와 학업적 자기효능감에 미치는 영향

배성훈(Seong-Hoon Bae) 한국콘텐츠학회 2022 한국콘텐츠학회논문지 Vol.22 No.6

본 연구의 목적은 플립드 러닝과 프로젝트 기반 학습을 결합한 메타버스 게임화 교수법으로 대학생들의 과제가치와 학업적 자기효능감을 향상시키고 이를 검증하는 것이다. 본 연구의 대상은 청주의 K대학교에서 상담심리학을 전공하는 16명의 대학생들이다. 대학생들은 각각 실험집단과 비교집단에 배정되었다. 실험집단에는 플립드 러닝과 프로젝트 기반 학습을 결합한 메타버스 게임화 교수법이 적용되었고 비교집단에는 단순 강의식 교수법이 적용되었다. 본 연구에서의 종속변인은 과제가치와 학업적 자기효능감이었다. 그리고 각 변인들을 사전, 사후에 측정하였다. 연구 결과 사후 검사에서 실험집단의 과제가치와 학업적 자기효능감은 비교집단에 비해 통계적으로 유의미하게 높았다. 본 연구의 결과는 플립드 러닝과 프로젝트 기반 학습을 결합한 메타버스 게임화 교수법이 대학생들의 과제가치 및 학업적 자기효능감의 향상에 효과적임을 시사한다. The purpose of this study was to improve and verify task value and academic self-efficacy of university students with metaverse gamification teaching method combining flipped learning and project-based learning. The subjects in this study were 16 university students majoring in counseling psychology who engaged in K university in cheong-ju. The subjects were assigned to the experimental group or the comparison group. The experimental group received the proposed metaverse gamification teaching method combining flipped learning and project-based learning while comparison group received teacher-centered learning. The dependent variables in this study were task value and academic self-efficacy. Each variable was assessed before class, after the end of the class. At the end of the class, the experimental group engaged statistically significantly higher levels of task value and academic self-efficacy than the comparison group. The findings of this study suggest that this metaverse gamification teaching method combining flipped learning and project-based learning is effective at improving task value and academic self-efficacy.