헤파린-플루로닉 나노젤의 세포내 흡입에 대한 키토산 코팅의 영향

최동훈,정윤기,박기동 한국생체재료학회 2010 생체재료학회지 Vol.14 No.2

Chitosan was coated on the surface of a nanogel composed of heparin and Pluronic (HP nanogel) were investigated about internalizing property into cytosol. The chitosan-coated HP (CHP) nanogel was made via the self-assembly by increasing temperature in an aqueous solution. The average diameter of CHP and HP nanogels significantly increased and the surface charge was changed to more positive charge as increasing the feed amount of chitosan, which was measured by dynamic light scattering (DLS) and ζ-potential. Intracellular uptake study demonstrates that a large amount of CHP and HP nanogels was internalized intro the cytosol, which was performed by fluorescence activated cell sorter (FACS) and confocal laser scanning microscopy (CLSM). Contrary to our expectation, the kinetics of intracellular uptake was similar under varied nanogel concentrations and incubation times, regardless of chitosan coating. In conclusion, obtained results demonstrate that chitosan coating on a HP nanogel does not affect significantly the intracellular uptake in spite of changed surface charges and hydrodynamic sizes.

Dimesggenic compounds consisting of cholesterol and fluorinated azobenzene moieties

최동훈,이우근,김규남,진정일 한국고분자학회 2007 한국고분자학회 학술대회 연구논문 초록집 Vol.2007 No.4

Induced Pluripotent Stem (iPS) Cells Behavior on PLGA-gelatin Film and Scaffold

최동훈,박귀덕,김익환,한동근 한국고분자학회 2009 한국고분자학회 학술대회 연구논문 초록집 Vol.2009 No.4

A dual growth factor delivery system of PLGA alginate microcapsules using a coaxial system

최동훈,한동근,김익환,박귀덕 한국고분자학회 2010 한국고분자학회 학술대회 연구논문 초록집 Vol.2010 No.4

CRYSTAL engineering by MESOSCOPIC AND microscopic Self-organization of 2-D Organic Semiconductors

최동훈,김경환 한국고분자학회 2010 한국고분자학회 학술대회 연구논문 초록집 Vol.2010 No.10

Diffraction behavior of photorefractive molecular material bearing the functional phenothiazine dimer

최동훈,김재홍,오광용,최석호,준웅기 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.2

We have developed a new multifunctional molecular glassy material, 2-(10-f6-[3-(diphenylhydrazonomethyl)- phenothiazin-10-yl]-hexylg-10H-phenothiazin-3-yl-methylene)-malononitrile, with the a unique charge transport phenomena and large photoactive property for photorefractive applications. The photorefractive sample with a mixture of 2-[10-(2-ethylhexyl)-10Hphenothiazin- 3-yl-methylene]-malononitrile(PM-1) and N'-[10-(1-(ethyl-heptyl)-10H-phenothiazin- 3-ylmethylene)-N,N-diphenyl- hydrazine(PH-1) showed a complementary grating behavior which could be explained by using the bipolar transport model. The transition from a bipolar transport phenomenon to a monopolar transport phenomenon was observed in the photorefractive composite bearing 2-(10-f6-[3-(diphenyl-hydrazonomethyl)-phenothiazin-10-yl]-hexylg-10Hphenothiazin- 3-yl-methylene)-malononitrile. We have developed a new multifunctional molecular glassy material, 2-(10-f6-[3-(diphenylhydrazonomethyl)-phenothiazin-10-yl]-hexylg-10H-phenothiazin-3-yl-methylene)-malononitrile,with the a unique charge transport phenomena and large photoactive property for photorefractiveapplications. The photorefractive sample with a mixture of 2-[10-(2-ethylhexyl)-10Hphenothiazin-3-yl-methylene]-malononitrile(PM-1) and N'-[10-(1-(ethyl-heptyl)-10H-phenothiazin-3-ylmethylene)-N,N-diphenyl- hydrazine(PH-1) showed a complementary grating behavior whichcould be explained by using the bipolar transport model. The transition from a bipolartransport phenomenon to a monopolar transport phenomenon was observed in the photorefractivecomposite bearing 2-(10-f6-[3-(diphenyl-hydrazonomethyl)-phenothiazin-10-yl]-hexylg-10Hphenothiazin-3-yl-methylene)-malononitrile.

석탄을 원료로한 활성탄 제조와 흡착특성에 관한 연구

최동훈,김형호,김종수,김재홍,김장호 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.2

The purpose of this study is develop manufacture technology of activated carbon for purification of water, it is investigated suitable manufactures for manufacture of activated carbon for purification of water by use anthracite coal and bituminous coal produced in internal and external through this fact, economic valuation and made method established. it is valuated wether or not suitable high degree purification by know removal characteristic organic matter such as KMnO₄Consumption, DOC, UV-254, and THMFP make use of Pilot-plant (purification of water treatment) for made activated carbon. For mixed anthracite coal and bituminous coal by means of coal tar pitch, completely melt to fixed coal tar pitch apply l50℃ heat at stainless steel box, since then compounding weight rate 1:l of anthracite coal and bituminous coal sieved material, then add coal tar pitch and caking water, mixed suitable compounding rate since then extrude and mix by diameter 5.5m extruder, extruded mold cute and dry length l0mm pellet shape by cutter and then made activated carbon.

연령과 골소주 특성의 골량에 대한 연관관계

최동훈,송영한,윤영남,이완,이병도 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.2

Purpose : Bony strength is dependent on bone mass and bony structure. So this study was designed to investigate the relationship between the bone mass and bony trabecular characteristics. Subjects and Methods : Study subjects were 51 females (average age 68.6 years) and 20 males (average age 66.4 years). Bone mineral density (BMD, grams/cm²) of proximal femur was measured by a dual energy X-ray absorptiometry (DEXA). Regions of interest (ROIs) were selected from the digitized radiographs of proximal femur. A customized computer program processed morphologic operations (MO) of ROIs. 44 skeletal variables of MO were calculated from ROIs on the Ward’s triangle and greater trochanter of femur. WHO BMD classes were predicted by MO variables of the same ROI. Classification and Regression Tree analysis was used for calculating weighted kappa values, sensitivity and specificity of MO. Results : The discriminating factors of morphologic operation were branch point, branch point [per cm sq]. Age also played important role in distinguishing osteoporotic classes. The sensitivity of MO at Ward’s triangle and Greater Trochanter was 91.8%, 65.6%, respectively. The specificity of MO was 100% at Ward’s triangle and Greater Trochanter. Conclusion : Bony trabecular characteristics obtained using radiological bone morphometric analysis seem to be related to bone mass.

상·하악 전치부의 근관치료에 사용되는 시술길이 (Working Length)에 관한 통계학적 연구

최동훈,박동수,이찬영,이정식 大韓齒科保存學會 1984 Restorative Dentistry & Endodontics Vol.10 No.1

This study was undertaken to obtain the average canal length of upper & lower anterior teeth which was important in canal length measuring procedure of endodontic treatment. It was based upon 827 out-patients who had endodontic treatment on their upper & lower anterior teeth at the Department of Operative Dentistry, Dental Infirmary, Yonsei Medical Center from February, 1978 to June, 1984. The 1249 teeth of these patients were devided into sex and age groups. The root canal length of these teeth were measured. The following results were obtained; 1. The mean root canal length of upper & lower anterior teeth were as follows; Upper central incisors : 21.8mm Upper lateral incisors : 21.0mm Upper canines : 24.1mm Lower central incisors : 18.6mm Lower lateral incisors : 19.9mm Lower canines : 22.6mm 2. There was no significant difference in root canal length between sex. (p>0.05) 3. There was no significant difference in toot canal length between age groups. (p>0.05) 4. The distribution of upper central incisors showed the highest distribution followed by upper lateral incisors and lower central incisors between 10 to 40 year old age groups, and there was no significant difference in the rest of the age groups. There was no significant difference in sex distribution, which was 49.5% for males and 50.4% for females. The number of the upper anterior teeth was 74.3% of all the specimens and the lower anterior 25.7%, and 40.6% of all the specimens were upper central incisors.

연해주 고려인들에게 내려진 희망의 비상사태

최동훈 전남대학교 글로벌디아스포라연구소 2007 전남대학교 세계한상문화연구단 국제학술회의 Vol.2007 No.11