Analysis of Fire Evacuation Behavior in a Primary School Environment

Lee,Chang-Seop,Kim,Hong,A,Kilpatrick,W,Fitzpatrick 한국화재소방학회 1997 한국화재소방학회 학술대회 논문집 Vol.1997 No.-

The paper compares the statutory requirements for the design mid construction of primary schools in Korea and Scotland with respect to fire safety and examines the attitudes to, and the behavior in, evacuation scenarios of Primary school Pupils in both countries. The key behavioral issues examined are the effectiveness of fire safety training, the level of teacher dependency, the effect of spatial organization and gender differences both within and between Korea and Scotland.

골수구성 백혈병 환자에게 발생한 결핵성 림프절염

이창섭,송진수,최평균,조재현,방지환,박경화,박완범,김홍빈,김남중,윤성수,박선양,김병국,오명돈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

혈액질환 가운데 결핵 발생이 증가한다고 알려진 것은 호지킨 림프종을 포함한 림프증식성질환 그리고 모양세포성 백혈병 등이 있다. 또한 동종 골수이식을 받은 환자에서도 결핵은 증가한다고 알려져있다. Kaplan 등은 골수구성 백혈병 환자에서 결핵 발생이 증가한다고 보고하였다. 그러나 골수구성 백혈병 환자에서 결핵의 발생이 증가하는 이유에 대해서는 아직까지 정확하게 밝혀지지 않았다. 저자들이 2년 동안 후향적으로 조사한 180명의 성인 골수구성 백혈병 환자들 가운데 결핵이 발생한 환자는 4명이었고, 발생 부위는 모두 림프절이었다. 결핵은 골수구성 백혈병의 특정 아형에만 국한되어 발생하지 않았지만, 50%에서 FAB 분류에 의한 M4였다. 림프절이 종대된 골수구성 백혈병 환자에서 특히, 결핵의 유병율이 높은 나라에서는 결핵성 림프절염도 감별진단에 포함시켜야 한다. During the neutropenic phase, leukemia patients receiving chemotherapy are prone to bacterial and, fungal infections; occasionally mycobacterial, viral and protozoal organisms may also cause infections. Mycobacterium tuberculosis infection was reported very rarely in these patients. This report describes four patients with M. tuberculosis infection identified from 185 adult patients who were diagnosed myelogenous leukemia between January 2003, and December 2004. There was no patient with M. tuberculosis infection from 44 lymphoid leukemia and 11 acute biphenotypic leukemia patients. Sites of infection were all lymph nodes. Three among four patients were presented with lymphadenopathy at initial diagnosis of leukemia, and the other one presented with lymphadenopathy after induction chemotherapy. There was no patient presented with lymphadenopathy during the neutropenic phase. Tuberculous lymphadenitis was presented in a patient with three acute myelogenous leukemia (FAB class 2 M4, 1 M2) and a chronic myelogenous leukemia, accelerated phase. An acute myelogenous leukemia patient had a leukemic cell and tubercle bacilli in the same lymph node. Tuberculosis should also be included as a differential diagnosis in myelogenous leukemia patient with lymphadenopathy, especially in the countries in which the disease is endemic.

초등 사회과 현장학습 실태분석

황홍섭,이상례 부산교육대학교 교육대학원 2001 논문집 Vol.3 No.-

The purpose of this study is to analyze a actual state of field-learning in elementary socal studies. Research was performed with teachers and students of the 4th grade who were divided by ward office. The recovery rate for teachers was 82% (41 of 50 teachers returned the questionnaire). The recovery rate for the students was 70.4% (317 of 450 students returned the questionnaire). The result of the analysis of the actual conditions of field-learning is the following : 1) Most of the teachers(92.7%) and students(83.9%) are aware that they need field-learning, but actual school conditions make them difficult owing to the lack of principals' and parents' awareness, lack of programs, problems of transportation, costs, and lack of cooperation among teachers. 2) Field-learning is usually performed by grade(75.6%), but teachers should have discretionary authority to carry out the field-learning by class, thus ensuring field-learning diversity, promptness, and seriousness. 3) Through this study, it was discovered that teachers are not aware of the importance of preliminary studies, and prepare only simple materials and a simple teaching plan before the field-learning. In addition, they avoid field-learnings because of the difficulties of preparing effective teaching materials. When they make teaching materials for the trip, they usually do it with students and use internet(39%) a little more than the text or guidance book(34.1%). 4) Teachers select the region for field-learning according to the curriculum(90.2%). Thus, we know that most teachers follow the curriculum closely. 5) According to this analysis of the actual conditions of regional field-learning, there is little difference in the needs of field-learning, the reason, frequency, or the methods. There is, however, some differences in preliminary studies, the method of study after the field-learning, and the experiences during the field-learning. It is reported students living in Eastern Busan city, experience more direct field-learning and make use of the Internet more than students of other wards. 6) The number of students that haven't experienced a variety of field-learnings is high, and they are in need of an organised program for field-learning. The field-learning that they experience is the following: cyber field-learning(25.6%), indirect field-learning(15.1%), role play(7.6%). It is suggested that direct field-learning is the best way of studying Busan and using the Internet is second. In conclusion, we should improve educational conditions for liberal field-learning. Teachers should be able to use discretionary time and special activity time freely, according to the 7th curriculum. But there should be approval from the principal before field-learning is conducted by class. Most importantly, teachers must have concern and desire for the field-learning. the main problem for teachers with regard to field-learning is the lack of programs for it. We need to develop organised programs.

PLC를 이용한 빙축열 시스템 운전제어에 관한 연구

남궁홍준,이윤섭 공주대학교 생산기술연구소 2002 論文集 Vol.10 No.-

PLC control system is composed of sensor transducer, analog-digital converter module, proportional integral differential module, digital-analog converter module, and PLC CPU. LabVIEW was made up a monitoring program for supervising and controllong in the actual spot. Ice storage system using heat pump is able to heating and air cooling. Heating is applied ice storage system's algorithm, air cooling is made use of new algorithm. In heating and air cooling, ice storage system using heat pump was selected LabVIEW for preceding control, it was put use LG Glofa PLC for subordinate control. I am confirmed that various working control is feasible through this thesis.

자가공명영상을 이용한 정신분열병 환자의 뇌량 면적 측정

박홍석,이정섭,황성혜,김창현 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 본 연구에서는 정신분열병의 병태생리에 뇌량이 관여하는지 확인하기 위해 초발 및 만성 정신분열병 환자, 대조군의 뇌량의 영역을 측정하였다. 방 법 : 국립의료원에 입원한 23명의 정신분열병 환자(남자 15명, 여자 8명)와 단순 두통 또는 어지럼증을 호소하여 내원한 23명의 외래환자를 대조군으로 하여 뇌자기공명영상을 얻었으며, 남자는 26명, 여자는 20명 이었다. 환자군중 초발군은 13명, 만성군은 10명이었다. 정중시상평면에서 뇌량을 7개 영역으로 구분하여 NIH Image 1.60프로그램으로 분석하였으며, 정중시상평면의 대뇌면적도 구하였다. 이렇게 구한 각 뇌량척도들은 t-test를 이용하여 대조군과 비교하였으며, 성별에 따른 차이는 ANOVA를 이용하였으며, 이후 대뇌면적을 공변량으로 하여 ANCOVA를 시행하였다. 또한 초발군과 만성환자군, 대조군의 비교는 나이와 대뇌면적을 공변량으로하여 MANCOVA를 시행하였다. 결 과 : 환자군과 대조군 사이의 총뇌량의 평균면적과 각 7부분의 평균면적을 비교한 결과 환자군이 제 3, 제 6 뇌량영역을 제외하곤 대조군에 비해 평균면적이 작은 것으로 나왔지만 통계적 유의성은 없었다. 성별에 따라 비교한 결과 통계적 유의성은 관찰되지 않았지만 남자환자는 대조군에 비해 작고, 여자환자의 경우에는 큰 것으로 확인됐다. 초발과 만성환자군으로 나누어 대조군과 비교해 본 결과, 통계적 유의성은 없었으나 초발환자군이 만성환자군에 비해 모든 뇌량척도가 작았고, 만성환자군은 대조군보다 총뇌량의 평균면적이 컸으나 초발군은 대조군 보다 작았다. 결 론 : 본 연구의 결과 정신분열병 환자에서 유의한 뇌량의 형태적 이상을 확인하지는 못했지만 이전 연구들에서도 다양한 결과들을 보고하고 있으며, 이는 정신분열병이 생물학적 및 임상적으로 각기 다른 표현형을 가지고 있다는 가설로 설명할 수 있다. Objectives : This study was performed to determine whether the corpus callosum is involved in pathophysiology of schizophrenia and measured corpus callosal areas of first episode, chronic schizophrenic patients and controls. Methods : We obtained the brain magnetic resonance imaging of 23 schizophrenic inpatients(15 males, 8 females) and 23 controls(11 males, 12 females) with simple headache or dizziness. Among the schizophrenic group, first episode patients were 13, chronic patients were 10. In mid-sagittal plane, the corpus callosum was divided into 7 areas and the cerebral area was measured. This data was analyzed with NIH image 1.60 software. We compared the corpus callosal areas of schizophrenics with controls by t-test and by ANOVA according to sex. Thereafter, ANCOVA was performed with mid-sagittal cerebral area as covariant. Comparison of first episode, chronic schizophrenics and controls was carried out by MANCOVA that was adjusted with age and mid-sagittal cerebra area. Results : The schizophrenics, compared with controls, had smaller corpus callosal areas except for the 3rd, 6th callosal area, but statistical significance was absent. According to sex, male schizophrenics had insignificantly smaller total callosal areas than male controls and female schizophrenics had larger ones. In comparison of first episode, chronic schizophrenic patients and controls, first episode patients had smaller every corpus callosal areas than chronic ones, chronic ones had larger total callosal area than controls and first episode ones had smaller total area than controls, but statistical significances were absent also. Conclusion : Our study did not reveal the structural abnormality of corpus callosum in schizophrenic patients, but many controversial results have been reported in other studies. This inter-study inconsistency could be explained by the hypotheses of not only clinical but also biological different phenotypes within the schizophrenia.

인간 면역부전 바이러스(HIV) 감염자 사이에서의 1기 및 2기 매독의 유행

장희창,조재현,박완범,이기덕,이창섭,김홍빈,오명돈,최강원 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 국내 HIV 감염자 사이에서 발생한 매독의 유행을 보고하고, 그 역학적 특성을 규명하고자 하였다. 재료 및 방법 : 1999년 7월부터 2003년 9월까지 서울대학교 병원에서 추적 관찰을 받아온 HIV 감염자를 대상으로 하여 1기 및 2기 매독의 발생을 조사하였다. 발생률을 정확히 구하기 위해 추적 관찰을 받은 모든 HIV 감염자의 인년을 6개월 간격으로 구하였다. 결과 : 51개월 동안, 465명의 HIV 감염자가 서울대학교 병원에서 추적 관찰을 받았다. 이중 38명이 1기 및 2기 매독으로 진단되었다. 1기 및 2기 매독의 발생률은 이기간 동안 100인년 당 4.1명이었다. 1999년 7월부터 2001년 12월 사이에는 발생자가 없었으나, 이후 발생률은 꾸준히 증가하여 2003년 9월에는 100인년 당 18.8명이 되었다. 1기 및 2기 매독의 발생률은 동성애자 및 양성애자에서 이성애자에서보다 4.3배 높았고, HAART로 치료를 받지 않은 환자에서 HAART로 치료를 받고 있던 환자에서 보다 10.9배 높았다. 결론 : 2002년부터 국내 HIV 감염자 사이에서 1기 및 2기 매독이 유행하기 시작하였고, 이러한 유행은 동성애자와 양성애자 및 HAART로 치료를 받고 있지 않던 사람 사이에서 발생하였다. Background : This study was performed to characterize the epidemiologic and clinical features of outbreak of syphilis among HIV sero-positive patients in Korea. Materials and Methods : A retrospective case review of patients diagnosed with primary and secondary syphilis from July 1999 to September 2003 was carried out at Seoul National University Hospital in Korea. To estimate the incidence, person-years (PYs) of all HIV sero-positive patients, who visited the hospital in the same period, were calculated every 6 months. Results : In a 51 month period, 465 HIV-positive patients were followed up at Seoul National University Hospital. 38 cases of primary and secondary syphilis were diagnosed. The incidence of primary and secondary syphilis was 4.1 per 100 PYs during the study period. There was no case from July 1999 to December 2001, and then the incidence rose until September 2003 from 5.5 per 100 PYs in 1999 to 18.8 per 100 PYs in 2003. The rate of primary and secondary syphilis was 4.3 times higher among homosexual and bisexual men than heterosexual men (95% CI 1.87 to 11.17), and 10.9 times higher among patients who did not receive HAART than patients who were receiving HAART (95% CI 5.47 to 21.79). Conclusion : The outbreak of primary and secondary syphilis among HIV-positive patients started in 2002 and has been escalating, especially among homosexual/bisexual men and in patients who did not receive HAART.

田作物 種子更新의 現況과 問題點

Hong Seok Lee(李弘䄷,),Chang Hwan Cho(曺章煥),Eun Seop Lee(李殷燮),Byong Hee Hong(洪丙憙),Eun Hee Hong(洪殷憙),Keun Yong Park(朴根龍) 한국육종학회 1985 한국육종학회지 Vol.17 No.3

For upland crops the returns from the investment in variety developmet and improvement are manifested through the increased production and superior quality of the crops grown from the new varieties. The varieties must be distributed widely, and rapidly, and sufficient seed or vegetatively propagated materials must be produced so that the varieties can be grown on the farms in the area in which it is adapted. The benefits from the improved varieties can be realized through growing the certified seed with sufficient genetic identity, purity and plumpness. Of the upland crops including wheat and barley, soybeans and other legumes, minor cereals and root and tuber crops, currently important crops were evaluated for the current situation and problems of seed renewing systems, and for the status of the crop production and demand and supply to find out practical problems in seed production. Solutions to the problems have generally been found from the investigation and long experience. For increased production and grain quality improvement of malting barley and rye, seed renewing programs should be strengthened in the near future. Certified seed supply and shortening of good quality seed renewing-year interval must be made through improvement of varietal and regional seed renewing systems. Particularly, for emergent need of wheat seed, foundation seed storing system must be established. In, soybeans six-year interval renewing system would be desirable in practice and should be fully practiced. Soybean seed production has been conducted by the Farmer’s Corporation Agency in accordance with increased soybean production assistance plan. However, certified seed production system and good quality seed production techniques must be applied desirably. Government-leading purchase price for the soybeans produced by farmers must be increased for farmers’ willingness to produce more soybeans. For corn sufficient amount of certified seed must be produced because a quantity of corn seed has been imported to meet the demand. In 1990, estimated amount of corn seed 1,500 to 2,000 M/T would be needed for silage and grain corn production. Past experience of suplus corn seed suggests that low temperature seed storage facility is to be facilitated for safe storage of high quality of corn seed.

전형적 및 비전형적 제1형 당뇨병에서 췌장소도 자가항체와 미토콘드리아 DNA 돌연변이의 빈도

이형우,이우제,김난희,이홍규,김상욱,박경수,홍성관,고경수,최동섭,김희진,이기업,이병두 대한당뇨병학회 1999 Diabetes and Metabolism Journal Vol.23 No.4

Double-stranded RNA induces iNOS gene expression in Schwann cells, sensory neuronal death, and peripheral nerve demyelination

Lee, Hyunkyoung,Park, Chanhee,Cho, Ik-Hyun,Kim, Hyun Yeong,Jo, Eun-Kyeong,Lee, Soojin,Kho, Hong-Seop,Choi, Se-Young,Bae Oh, Seog,Park, Kyungpyo,Kim, Joong Soo,Lee, Sung Joong Wiley Subscription Services, Inc., A Wiley Company 2007 Glia Vol.55 No.7

<P>Inflammation in the peripheral nervous system (PNS) is one of the characteristics of virus-induced peripheral neuropathy. In this inflammatory response, Schwann cells are actively involved. Previously, toll-like receptor 3 (TLR3) was reported as a receptor for double-stranded RNA (dsRNA) that induces antiviral and inflammatory responses in cells of the innate immune system. In this study, we investigated the expression and putative role of TLR3 in Schwann cells. TLR3 was constitutively expressed in Schwann cells. Stimulation with polyinosinic–polycytidylic acid, a synthetic dsRNA analogue, induced the expression of inducible nitric oxide synthase (iNOS) gene in Schwann cells. Studies on the intracellular signal transduction pathways using iSC, an immortalized Schwann cell line, revealed that dsRNA induces the activation of NF-κB, p38, and c-Jun N-terminal kinase (JNK). The activation of NF-κB, p38, JNK, and dsRNA-dependent protein kinase is required for dsRNA-mediated iNOS gene expression. However, the activation of PI3 kinase and GSK-3β inhibited iNOS gene induction, a process mediated by their inhibitory effects on NF-κB and p38 activation. dsRNA-induced NO production caused neuronal cell death in cultured dorsal root ganglion. Finally, the introduction of dsRNA into the rat sciatic nerve induced iNOS gene expression and peripheral nerve demyelination in vivo. Taken together, these data suggest that viral RNA may induce inflammatory Schwann cell activation via TLR3 and peripheral nerve damage in the PNS. © 2007 Wiley-Liss, Inc.</P>

The changed of muscle activation during different visual sign in bridging exercise: Randomized controlled trial

Lee, Young-Hyen,Lee, Bo-Eun,Lee, Dong-Yeop,Hong, Ji-Heon,Yu, Jae-Ho,Kim, Jin-Seop Diva Enterprises Private Limited 2018 Indian journal of public health research & develop Vol.9 No.11