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박홍석 대한영상의학회 1997 대한영상의학회지 Vol.37 No.2
Purpose : To describe the MRI findings of trigeminal neurinoma.Materials and Methods : We retrospectively analyzed the MRI findings of 19 patients with trigeminal neurinomas proven by surgery and pathologic examination. Axial T1- and T2-weighted MR images in all patients and gadolinium-enhanced T1-weighted images in 14 patients were obtained at 2.0T(8 cases), 1.5T(6 cases) or 0.5T(5cases). These were analyzed in terms of tumor size, signal intensity, degree of contrast enhancement, the presence or absence of cystic change and denervation atrophy of the masticator muscles.Results : Clinical manifestations included sensory abnormality or pain(n=12), headache(n=10), impaired visual acuity or diplopia(n=6), hearing loss or tinnitus(n=3), weakness of masticator muscles(n=2), and mass or nasal obstruction(n=2). On MR images, tumor size was seen to average 4.2(range 1.5-6)cm; tumors were located in the posterior cranial fossa(n=8), middle cranial fossa(n=4), ophthalmic nerve(n=2), maxillary nerve(n=1), and mandibular nerve(n=1), and in three cases were dumbbell-shaped and extended into both the middle and posterior cranial fossa. On T1-weighted images, signals were isointense with cortical grey metter, in ten cases(53%), and of low intensity in nine(47%); on T2-weighted images, signals were of high intensity in 15cases(79%) and were isointense in four (21%). Cystic change was seen in 12 cases(63%). After enhancement, all involved the trigeminal ganglion or mandibular nerveConclusion : A trigeminal neurinoma shows similar signal intensity and enhancement to other cranial neurinomas with a higher incidence of cystic degeneration. Its location and shape are characteristic, and where there is involvement of the trigeminal ganglion or mandibular nerve, denervation atrophy may be seen.
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박홍석,장기현,한문희,심정석,이상현,송재우,유인규,정희원,연경모 대한영상의학회 1996 대한영상의학회지 Vol.35 No.4
Purpose : To describe clinical and MRI findings of growth hormone-secreting pituitary adenoma, to determine ifthere are any characteristic MRI findings different from those of other pituitary adenomas, to evaluate therelationship between tumor size and serum growth hormone level, and to assess the results of immunohistochemicalstudy. Materials and Methods : We retrospectively analysed clinical and MRI findings of 29 patients with growthhormone-secreting pituitary adenoma confirmed by serum growth hormone level and surgery. We also evaluated therelationship between the tumor volume and serum growth hormone level, and the results of immunohistochemicalstudy. Coronal and sagittal T1-weighted MR images in all patients and gadoliniumenhanced T1-weighted MR images in28 patients were obtained with 2.0 T(24 cases) and 0.5 T(5 cases) MR imagers. The images were analyzed in terms oftumor size, signal intensity, degree of contrast enhancement, extent of tumor growth and the presence or absenceof cystic change, hemorrhage and calcification. Results : Clinical manifestations included facial feature changeand soft tissue swelling of hands and feet(n=29), headache(n=12), impaired visual acuity(n=9), symptoms ofhyperprolactinemia(n=8), visual field defect(n=5), and others(n=6). On MR images, all of the 29 cases were seen tobe macroadenomas and the size of the tumors averaged 2.2cm(1-5.2 cm). Supra- and infrasellar extensions were seenin 21 and 22 patients, respectively. Cavernous sinus invasion was noted in seven, and in one this was bilateral.Signal intensity was isointense with cortical grey matter in 26 cases(90%). Cystic change or necrosis was seen ineight cases(28%), hemorrhage in four(14%), and calcification in two(7%). After enhancement, most(25/28) of thetumors enhaned less than mormal pituitary in degree. There was no correlation between serum growth hormone leveland tumor size. Immunohistochemical study showed positive growth hormone-secreting cells in only 69%(11/16).Conclusion : Clinical findings in patients with growth hormone-secreting pituitary adenomas were various andincluded acromegaly, headache, visual impairment, and symptoms of hyperprolactinemia, for example. On T1-weightedMR images, all tumor were macroadenoma, and there were no characteristic findings different from those of otherpituitary tumors. The volume of a tumor did not correlate with serum hormone level. Immunohistochemical studyshowed positive growth hormone-secreting cells in a limited number of cases.
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문헌정보학의 학문적 역할 및 위치 -이용자 연구 중심의 문헌정보학-
박홍석 한국도서관정보학회 1997 한국도서관정보학회지 Vol.26 No.-
The library collects relevant documents, organizes these documents, retrieves and provides relevant documents, and helps the user use provided documents. These library activities are the distribution process of relevant documents in a society, and the role of library science is to deal with several problems in this process. This process is to facilitate the production of socially relevant documents, to select documents relevant to an individual user, and to enable the user to use the selected documents. As a result, this process should be based on the concept of "relevance". As a result, the academic role of library science should be considered based on "relevance". "Relevance" is getting more important to meet the change of the environment of library services, which is getting more complex and changing rapidly because of the computer and the computer network. It is true that these are very important tool for document distribution. However, the problems in the document distribution can not be solved only by the simple development of these tools because these have been caused by the simple development of these tools. These problems can be solved only through many studies of the user, which is the destination of document distribution, and through a n.0, pplying the results of these studies to designing these tools.dies to designing these tools.
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이용자 문제의 구조와 이의 이용자 문제 지향적 정보검색에 대한 적용 -대학원에서의 학술 연구과제를 대상으로 한 사례연구-
박홍석 한국문헌정보학회 1995 한국문헌정보학회지 Vol.28 No.-
The purpose of information retrieval is to help users solve their problems. To fulfill the purpose the user's problem needs to be focused on. The purpose of this study is to identify components and the structure of the user's problem in an academic research environment. From this study it was found that the scientific problem dealt within an academic environment is complicate and the problem is composed of 8 topical and 4 non-topical components. And they could be organized into a stucture. This study has three implications for user-oriented information retrieval. (1) The components and the structure of the problem need to be the framework for the effective information retrieval process and for the evaluation of information retrieval. (2) The research methodology used in this study can be applied to other information service situations and this will result in greater practical implication of a study for more effective information retrieval. And (3) for more effective user-oriented information retrieval, the user needs to be observed and studied in the actual situation. This study showed that the complicate problem of the actual user can be studied in a systematic way and this resulted in important implications for information retrieval
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