An enhanced bandwidth planar inverted‐F antenna with a modified shorting strip

Park, Hoon,Jung, Heekyung,Hong, Sukjin,Choi, Jaehoon Wiley Subscription Services, Inc., A Wiley Company 2007 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.49 No.3

<P><B>Abstract</B></P><P>This article presents a novel design method for a wideband planar inverted F‐antenna that simultaneously covers GSM900, GPS, DCS1800, IMT2000, WLAN, and DMB services. The proposed antenna consisted of a main patch with stubs, an I‐shaped patch, and a modified shorting strip. It had dimensions of 16 × 36 × 6 mm<SUP>3</SUP>. The dual band characteristic could be achieved by changing the length of a main patch. A very wide impedance bandwidth characteristic was obtained by optimizing the length of stubs, an I‐shaped patch, and a modified shorting strip. Commercial electromagnetic software, CST Microwave Studio, was used to design the structure. The maximum gains at the frequencies of 915, 1576, 1785, 2170, 2400, and 2630 MHz were 1.0, 2.7, 5.4, 4.56, 1.52, and 2.95 dBi, respectively. The overall radiation pattern was suitable for mobile applications. © 2007 Wiley Periodicals, Inc. Microwave Opt Technol Lett 49: 513–515, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.22179</P>

Analog predistortion linearization of Doherty power amplifiers using bandwidth reduction of error signal

Lee, Yong-Sub,Lee, Mun-Woo,Kam, Sang-Ho,Jeong, Yoon-Ha Wiley Subscription Services, Inc., A Wiley Company 2010 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.52 No.6

<P>This article represents analog predistortion linearization of Doherty power amplifier (DPA) using bandwidth reduction of error signal. To verify our methods, two DPAs are implemented using a push-pull GaN HEMT and a push-pull Si LDMOS at 2.14 GHz and tested using the memory-compensated analog predistorter with transistor-based error generators and three-branch nonlinear paths. From the measured four-carrier WCDMA results, the proposed analog predistortion DPAs show the significant linearity improvement. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1313–1316, 2010; Published online in Wiley InterScience (www.interscience. wiley.com). DOI 10.1002/mop.25190</P>

A broadband linearization method using a novel opto-electrical predistorter for radio-over-fiber systems

Moon, Yon-Tae,Choi, Woon-Kyung,Choi, Young-Wan Wiley Subscription Services, Inc., A Wiley Company 2010 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.52 No.7

<P>A broadband linearization method with a novel opto-electrical predistorter was experimentally demonstrated. With the proposed method, the third-order intermodulation distortion was simultaneously enhanced by more than 10 dB for 510 MHz ranges and by 24 dB at 2.2 GHz without any change in electrical circuitry. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1638–1640, 2010; Published online in Wiley InterScience (www.interscience. wiley.com). DOI 10.1002/mop.25240</P>

DVB-H antenna structure using Z-type hexagonal ferrite for folder-type mobile phones

Rhyu, Hanphil,Jung, Chang Won,Lee, Byungje Wiley Subscription Services, Inc., A Wiley Company 2009 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.51 No.9

<P>A new internal antenna structure using a Z-type hexagonal ferrite is introduced for the DVB-H reception in folder-type mobile phones. The antenna element operates as a coupling element to excite the chassis as a radiator. Using a Z-type hexagonal ferrite, the proposed antenna can be designed with a considerably low volume of 0.75 cm<SUP>3</SUP> and meets the requirements of antenna for the DVB-H service. The high isolation over 15 dB between the DVB-H band and the communication bands (GSM, DCS, and PCS) is obtained. © 2009 Wiley Periodicals, Inc. Microwave Opt Technol Lett 51: 2196–2199, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.24551</P>

Pretreatment anemia is associated with poorer survival in patients with stage I and II gastric cancer

Shen, Jian Guo,Cheong, Jae Ho,Hyung, Woo Jin,Kim, Junuk,Choi, Seung Ho,Noh, Sung Hoon Wiley Subscription Services, Inc., A Wiley Company 2005 Journal of surgical oncology Vol.91 No.2

<B>Background and Objectives</B><P>A negative correlation between anemia and outcome has been demonstrated in various cancers treated with radiotherapy. However, it is rarely studied whether this correlation may exist in surgical setting. Our aim was to investigate the relationship between pretreatment anemia and survival in surgically treated patients with gastric cancer.</P><B>Methods</B><P>A total of 1,688 patients who had undergone curative resection for gastric cancer between 1991 and 1995 were reviewed. Anemia was defined as a hemoglobin level <12.0 g/dl. The influence of anemia on patient overall survival was evaluated by univariate and multivariate analysis.</P><B>Results</B><P>Pretreatment anemia was present in 39.9% of the patients. The 10-year overall survival rate in anemic patients was 48.2% as compared with 62.6% in nonanemic patients (P < 0.001). In subgroup analysis according to the stage, the significant difference in 10-year overall survival rate between anemic and nonanemic patients was found in stage I and II gastric cancer (76.1% vs. 83.5% in stage I, P = 0.030; 55.1% vs. 67.2% in stage II, P = 0.043). On multivariate analysis, anemia was an independent prognostic predictor in patients with stage I and II disease (P = 0.007; RR, 1.466; 95% CI, 1.109–1.937).</P><B>Conclusions</B><P>Pretreatment anemia was found to have an independent relationship to the long-term survival of patients with stage I and II gastric cancer. J. Surg. Oncol. 2005;91:126–130. © 2005 Wiley-Liss, Inc. J. Surg. Oncol. 2005;91:?–?. © 2005 Wiley-Liss, Inc.</P>

Transforming growth factor-β3-induced Smad signaling regulates actin reorganization during chondrogenesis of chick leg bud mesenchymal cells

Kim, Dongkyun,Kim, Jungsoo,Kang, Shin-Sung,Jin, Eun-Jung Wiley Subscription Services, Inc., A Wiley Company 2009 Journal of cellular biochemistry Vol.107 No.4

<P>Endochondral ossification is characterized by a significant interdependence between cell shape and cytoskeletal organization that accompanies the onset of chondrogenic signaling. However, the mechanisms mediating these interactions have not been well studied. Here, treatment with transforming growth factor (TGF)-β3 at a later stage of chondrogenesis led to activation of Smad-2 signaling and the formation of intense stress fibers, which resulted in suppressing chondrogenic differentiation of leg bud mesenchymal cells. Moreover, specific siRNA knockdown of Smad-2 reduced TGF-β3-induced stress fibers via physical interactions with β-catenin. In conclusion, our results indicate that TGF-β3-induced Smad signaling, in conjunction with β-catenin, is involved in the reorganization of the actin cytoskeleton into a cortical pattern with a concomitant rounding of cells. J. Cell. Biochem. © 2009 Wiley-Liss, Inc.</P><P>This article was published online on 28 May 2009. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected 8 June 2009. J. Cell. Biochem. 107: 622–629, 2009. © 2009 Wiley-Liss, Inc.</P>

A new K-band push-push VCO using a miniaturized hairpin resonator

Lee, Hyun-Wook,Yoon, Ki-Cheol,Nam, Hee,Eo, Yun-Seong,Lee, Jong-Chul Wiley Subscription Services, Inc., A Wiley Company 2010 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.52 No.3

<P>In this article, a K-band push-push Voltage Controlled Oscillator (VCO) is presented using a miniaturized hairpin resonator (MHR) with a higher loaded quality factor and the reduced circuit area within 50% compared to the conventional one at 9.2 GHz.The MHR combined with the GaAs MESFET varactor shows a tuning range of 140 MHz, and this voltage tunable MHR is used to compose a push-push VCO. It provides the frequency tuning range of 71 MHz with flatness of +0.13 dB, which is increased by 31 MHz compared to the conventional VCO. The voltage controlled push-push oscillator based on the series feedback topology is implemented on 0.54 mm-thick Teflon substrate with a dielectric constant of 2.54. The measurement shows the output power of 1.18 dBm, the fundamental signal power suppression of −33 dBc, and phase noise performance of −86.78 dBc/Hz at 100 kHz offset. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 699–701, 2010; Published online in Wiley InterScience (www.interscience. wiley.com). DOI 10.1002/mop.25007</P>

Identification of novel gastric cancer-associated CNVs by integrated analysis of microarray

Park, Chan-Hee,Rha, Sun-Young,Jeung, Hei-Cheul,Kang, Seung-Hui,Ki, Dong-Hyuk,Lee, Won-Suk,Noh, Sung-Hoon,Chung, Hyun-Cheol Wiley Subscription Services, Inc., A Wiley Company 2010 Journal of surgical oncology Vol.102 No.5

<B>Background</B><P>Microarray-CGH facilitates analysis of cancer-associated genomic differences between normal and tumor tissues and provides a genome-wide assessment of copy number variations (CNVs).</P><B>Methods</B><P>To identify CNVs and their clinical significance in gastric cancer, Microarray-CGH was performed to identify CNVs with genomic DNA (gDNA) from normal placenta tissue, peripheral blood mononuclear cells (PBMCs), and normal gastric tissue.</P><B>Results</B><P>A total of 20 CNVs, including 8 novel CNVs, were identified by Microarray-CGH. Among the 20 CNVs, 5 showed an aberration frequency of over 50%. In addition, mRNA expression of W72437 (TFIIH), AI968311 (GAGE10), AI352361, and AA169807 (PTCH1) in normal tissues and AA485362 (GPX1), AI201652, and AI968311 (GAGE10) in cancer tissues was associated with DNA change. As a whole, incidences of oncogene-like, suppressor-like, and innocent CNVs were 13.8%, 13.2%, and 73.0%, respectively (gain 11.4%, loss 11.8%). AA936795 (C19orf61) appeared as an oncogene-like CNV (9/30, 30%), A1352361 (13/30, 43%), and AA281797 (LOC728340, 10/30, 33%) appeared as tumor suppressor-related CNVs.</P><B>Conclusions</B><P>This study identified gastric cancer-associated and innocent CNVs in gDNA isolated from placenta tissue and PBMC, which are generally used as reference samples in Microarray-CGH. These novel CNVs may be used for gastric cancer-specific gene selection in comparative analysis of genomics. J. Surg. Oncol. 2010;102:454–461. © 2010 Wiley-Liss, Inc.</P>

Fast 3D ¹H MRSI of the corticospinal tract in pediatric brain

Kim, Dong-Hyun,Gu, Meng,Cunningham, Charles,Chen, Albert,Baumer, Fiona,Glenn, Orit A.,Vigneron, Daniel B.,Spielman, Daniel Mark,Barkovich, Anthony James Wiley Subscription Services, Inc., A Wiley Company 2009 Journal of Magnetic Resonance Imaging Vol.29 No.1

<B>Purpose</B><P>To develop a <SUP>1</SUP>H magnetic resonance spectroscopic imaging (MRSI) sequence that can be used to image infants/children at 3T and by combining it with diffusion tensor imaging (DTI) tractography, extract relevant metabolic information corresponding to the corticospinal tract (CST).</P><B>Materials and Methods</B><P>A fast 3D MRSI sequence was developed for pediatric neuroimaging at 3T using spiral k-space readout and dual band RF pulses (32 × 32 × 8 cm field of view [FOV], 1 cc iso-resolution, TR/TE = 1500/130, 6:24 minute scan). Using DTI tractography to identify the motor tracts, spectra were extracted from the CSTs and quantified. Initial data from infants/children with suspected motor delay (n = 5) and age-matched controls (n = 3) were collected and N-acetylaspartate (NAA) ratios were quantified.</P><B>Results</B><P>The average signal-to-noise ratio of the NAA peak from the studies was ≈22. Metabolite profiles were successfully acquired from the CST by using DTI tractography. Decreased NAA ratios in those with motor delay compared to controls of ≈10% at the CST were observed.</P><B>Conclusion</B><P>A fast and robust 3D MRSI technique targeted for pediatric neuroimaging has been developed. By combining with DTI tractography, metabolic information from the CSTs can be retrieved and estimated. By combining DTI and 3D MRSI, spectral information from various tracts can be obtained and processed. J. Magn. Reson. Imaging 2009;29:1–6. © 2008 Wiley-Liss, Inc.</P>

Pharmacokinetics and therapeutic effects of oltipraz after consecutive or intermittent oral administration in rats with liver cirrhosis induced by dimethylnitrosamine

Bae, Soo K.,Lee, Shin J.,Kim, Taekrho,Kim, Jin W.,Lee, Inchul,Kim, Sang G.,Lee, Myung G. Wiley Subscription Services, Inc., A Wiley Company 2006 journal of pharmaceutical sciences Vol.95 No.5

<P>Pharmacokinetics and therapeutic effects of oltipraz were evaluated after consecutive (once per day at 30 mg/kg/day for 7 and 14 days) or intermittent (once per week at 100 mg/kg/week for 1–3 weeks) oral administration to rats with liver cirrhosis induced by dimethylnitrosamine. The AUC of oltipraz was significantly greater in cirrhotic rats than controls (890 compared with 270 µg · min/mL) due to impaired liver function in cirrhotic rats. However, the AUC values after consecutive 7 (421 compared with 753 µg · min/mL) and 14 (309 compared with 821 µg · min/mL) days oral administration of oltipraz in cirrhotic rats were significantly smaller than those in respective vehicle-treated cirrhotic rats. Moreover, the AUC values after intermittent 2 and 3 weeks in cirrhotic rats were also significantly smaller than that in 1 week vehicle-treated cirrhotic rats (2370 and 1690 compared with 4760 µg · min/mL). This could be due to induction of CYP isozymes and considerably greater numbers of normal liver cells in cirrhotic rats by oral administration of oltipraz. Improved liver function by oltipraz in cirrhotic rats was proved by liver microscopy; livers are free of significant fibrosis, although evidence of bridging necrosis is still present in many rats. © 2006 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 95:985–997, 2006</P>