젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

정보 활용의 실천력을 향상시키는 ICT 활용 교수-학습 모형

권지영,권보섭,송희헌 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.3

현재의 ICT 활용 교육은 소양 교육에 초점을 두고 단순히 정보통신의 기능을 습득하는 기술적인 면에 치우치는 문제점을 가지고 있다. 본 연구에서는 이와 같은 문제점을 해결한 ICT 활용 교수-학습 모형을 제안한다. 제안된 모형은 기존의 교수-학습 유형별 ICT 활용 모형들에 대해 정보활용의 실천력을 조사하고 분석한 다음, 이를 평가할 수 있는 질적 기준이 교수-학습 모형에 균형있게 반영되도록 하였다. 적용 결과, 정보 활용의 실천력을 질적으로 평가해 주는 6개 항목 중 5개 항목에서 유의미한 향상이 있음을 보였다. The present instruction using ICT has a problem that it inclines toward instructing the simple technique of information or communication technology. In this paper, to cope with this problem, we propose a new Teaching-Learning model using ICT. The previous teaching-learning models using ICT are investigated and analyzed. Then, the criteria for evaluating the ability to put information literacy into practice are evenly reflected in the proposed model. is evenly reflected. The result of experiment reveals that the proposed model enhances the ability to put information literacy into practice on 5 items of 6 qualitative evaluation criteria.

소득작물 전후작지 적응 극단기성 벼 ‘중모 1032’

손영보,이종희,조준현,이지윤,오성환,송유천,박동수,박노봉,김상열,여운상,남민희,권영업 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

리듬체조 수직 점프 시 슈즈의 깔창 유뮤에 따른 수직 지면반력과 하지관절각의 차이

권보영 이화여자대학교 동작과학연구소 2006 이화체육논집 Vol.9 No.-

The use of forefoot insoles reduced the number of passive peaks during landing. Since rhythmic gymnasts subject their bodies to large amounts of stress, it is recommended that all rhythmic gymnasts use forefoot insole to reduce impact forces on the body during landing. Furthermore, bending at the hips, knees and ankles proved to be important. During landing, there was a negative correlation between hip joint angle and impact force. Thus, as hip angle increases, impact force is reduced. Therefore, it can be concluded that rhythmic gymnasts can reduce impact force on their bodies by increasing hip angle during landing. In the knee and ankle, as angle decreases active loading rate increase. An increasing active loading rate signifies rapid, energetic movement both downward and upwards during landing. These quick, sharp landings not only showed high values for maximum active loading rate, but also displayed a nearly symmetrical rate of decay for active force. This might indicate a relationship between both active rate values and active decay rate values. This relationship, as well as angular velocity during these time periods should be investigated further in future studies. Although the aesthetics of rhythmic gymnasts emphasize upright body position after landing, it is critically important for gymnasts to bend at the hips, knees and ankles. While these movements seen contrary to the aesthetics of the sport, when performed rapidly with an equally rapid return to an upright position, the gymnasts are able make their landings seem light and effortless. Analysis of ground reaction forces can help gymnasts balance the reduction impact forces, while preserving the aesthetics of their performances. Furthermore, continued analysis of ground reaction force should focus on helping rhythmic gymnasts optimize their performance of vertical jumps. For example, studying the correlation between active loading rate and active decay rates, as well as studying joint angle during these two different periods can provide a great deal of useful information for future analysis. Finally, future studies should also include a much larger sample size in order to increase the validity of the results.

제2형 당뇨병 환자에서 우연히 발견된 기종성 방광염 1례

박보민,김윤정,이영태,노정현,권수경,김동준,고경수,이병두,임경호,이순희,박정현 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Emphysematous cystitis is an uncommon disease in which bacterias produce gas within the bladder wall and surrounding tissue. Patients with diabetes, neurogenic bladder and chronic urinary tract infection are predisposed to the disease. It is usually caused by E.coli and Klebsiella. Severity of illness ranges from an asymtomatic condition to life threatening cystitis. Succesful management depends on early diagnosis with correction of underlying causes, administration of appropriate antibiotics, establishment of adequate bladder drainage and surgical excision of involved tissue when required. We report a case of 52-year-old woman who did not compain of symtoms of cystitis but epigastric pain, nausea, and vomitting. Emphysematous cystitis was revealed on the abdominal X-ray series incidentally. CT scans of the pelvis showed mottled gas bubble within the bladder. After treatment, the symtoms subsided and plain abdominal film showed no evidence of gas shadow in the pelvic cavity.

흰쥐 경동맥 풍선손상 모델에서 리포좀 전달체를 이용한 에스트로겐의 국소전달 효과

윤영섭,장양수,정광회,박요석,김형관,강웅철,권진욱,정보영,조상호,김성순 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

특발성 과호산구 증후군 환자의 치료 도중 발생한 간혈종 1례

이영태,김동기,박지훈,김윤정,김기향,박보민,권민정,김애란,이원식,주영돈,손창학 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Idiopathic hypereosinophilic syndrome is characterized by marked elevation of eosinophil count ( >1,500/㎣) in peripheral blood without explaining etiology. It shows tissue involvement in many organs such as liver, G-I tract, myocar dium, lung, skin, kidney and nerve. Some case of hypereosinophilic syndrome with hepatic involvement have been reported, but not much. We have recently experienced a case with idiopathic hypereosinophilic syndrome of a 40 year old man who presented with RUQ pain. By abdominal CT, ill- defined subcapsular hematoma was detected. Liver biopsy showed eosinophilic infiltration within the portal tract and sinusoid. Drain procedure and corticosteroid adminiiatbrought marked improvement of clinical manifestation, hematologic abnormality and radiologic abnormality.

結晶粒成長에 미치는 Zener-drag에 관한 二次元 모델 실험

李寶永,權五鍾 경북대학교 공과대학 1986 工大硏究誌 Vol.15 No.-

Two-dimensional bubble model experiment has been carried out to test Zener drag of dispersed particles on grain growth in metals. Simple two-dimensional model of bubble cell growth was suggested. In the case of uniform initial bubble size, cell diameter increased very slowly at early stage. But after wide cell size-distribution appeared, cell size increased as fast as the normal growth, which occured in the bubbles having a heterogeneous size-distribution. In the case of the addition of second phase particles, the growth of bubble cells stopped when the cell size reached a certain critical size, after that no subsequent growth was observed. With increasing amount of dispersed particles, the maximum cell size became smaller, and the pinning time became shorter. The time-dependence exponent n in the growth kinetic equation, D?=kt^n, observed to be 0.39 independent of the presence of the second phase dispersed particles. In conclusion, dispersed particles can stop effectively the grain growth in metals at high temperature.

피부종양에서 Single-strand Conformation Polymorphisms 법에 의한 p53 유전자 돌연변이 검색

류영욱,손보성,권호준,이규석,송준영 啓明大學校 醫科大學 1995 계명의대학술지 Vol.14 No.4

The tumor suppressor gene p53, located on the short arm of chromosome 17, encodes for nuclear protein which regulates cell proliferation by inhibiting cells entering S-phase. Mutation in p53 gene are the most frequent genetic alteration found in human cancers to date. This study was examined mutant p53 gene mutation using PCR-SSCP method and mutant p53 oncoprotein expression using avidin biotin peroxidase complex method immunohistochemically, in 2 seborrheic keratosis, 3 basal cell carcinoma, 3 squamous cell carcinoma and 1 metaststic squamous cell carcinoma cases. With PCR-SSCP methods in exon 5 and 7, no genetic mutation of p53 gene was observed in 2 seborrheic keratosis, 3 basal cell carcinoma, 3 squamous cell carcinoma, and 1 metaststic squamous cell carcinoma cases. With immunohistochemical staining with ABC method, a case of squamous cell carcinoma developed on lower lip was positive but another were all negative. This result means that p53 gene mutation on skin tumor may develope in squamous cell carcinoma developed on sun exposed area and this mutation on squamous cell carcinoma can develope other exonal site except exon 5 and 7.

베체트병 환자에서 Azathioprine으로 유발된 급성 췌장염 1례

김기향,권민정,김동기,김애란,김윤정,박지훈,이영태,박보민,김동욱 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Although many drug are thought capable of initiating acute pancreatitis, following azathioprine administration represents the 5% incidence by far the highest recorded incidence to date. We report a 35-year-old male who developed acute pancreatitis in the course of treatment with azathioprine for Behcet's disease. He was admitted due to abdominal pain, diarrhea, and fever for 10 days. Serum amylase and lipase levels were 510U/L and 3702U/L respectively. The abdominal CT scan revealed diffuse enlargement of the pancreas. There was no history of alcohol use or gall bladder disease. We considered drugs, especially azathioprine, as the cause of acute pancreatitis. We diagnosed it as acute pancreatitis. The patient was treated conservatively with hydration and analgesics. The symptom subsided within four days. Five days later, azathioprine was resumed. And the patient complained of abdominal pain. The elevated levels of serum amylase and lipase confirmed the recurrence of pancreatitis. His symptom subsided when azathioprine intake the stopped, and the serum amylase and lipase levels returned to normal level within five days.