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      • KCI등재

        소음인(少陰人) 태음병(太陰病) 심하비증(心下?證)의 병증약리(病證藥理) 고찰

        서영광,이지원,이준희,최원철,이의주,고병희,Seo, Young-Kwang,Lee, Ji-Won,Lee, Jun-Hee,Choi, Won-Cheol,Lee, Eui-Ju,Kho, Byung-Hee 사상체질의학회 2010 사상체질의학회지 Vol.22 No.3

        1. Objective: Gastric Stuffiness (心下?證) in the Soeumin Taeeum symptomatology (少陰人 太陰病) in Sasang Constitutional Medicine shows an interesting evolutionary process. Originally found in the texts of Sanghanlun (傷寒論), the perspectives regarding the symptoms of Gastric Stuffiness were expanded by many medical scholars and Lee Jema. To comprehend the Jema's concept of Taeeum symptomatology and utilize his prescription clinically, it deserves to study on the Gastric Stuffiness in Donguisuseowon (東醫壽世保元). 2. Methods: Many texts including Sanghanlun (傷寒論) and Dongeuibogam (東醫寶鑑) were reviewed in order to track the evolutionary process concerning the symptoms of Gastric Stuffiness. Also, Lee Jema's works including the different versions of Donguisuseowon (東醫壽世保元) were reviewed to examine the development of Lee's concepts regarding the Gastric Stuffiness in the Soeumin Taeeum symptomatology. 3. Results and Conclusions: 1) Most of the previous concepts on Gastric Stuffiness were generally similar to those found in Sanghanlun, especially in that they addressed Yang deficiency of the middle triple energizeer as the central pathogenic process. 2) Lee Jema's views on the epigastric discomfort in the Soeumin Taeeum symptomatology evoloved over time and culminated in the finalized pathology and therapeutics appearing in his last work, the Shinchuk version of Donguisuseowon (東醫壽世保元). 3) 4 kinds of prescription which invented by Lee Jema to treat the Gastric Stuffiness in the Soeumin Taeeum symptomatology can be matched to the prescription of Sanghanlun respectively. However through evolutionary process of Jema's prescriptions, the indication of them expanded: not only to treat Gastric Stuffiness but to diverse symptoms of Soeumin.

      • 췌장 선방세포암 1예

        이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

        Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

      • 원발성 후복막 점액낭샘암종 1예

        지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

        Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

      • 공구 수명의 신뢰성 예측 프로그램 개발

        이수훈,김봉석,강태한,송준엽,강재훈,서천석 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

        This paper deals with a prediction method of tool life in view of the reliability assessment. In this study, the flank wear was studied among multi-factors deciding the tool wear state. Firstly, tool life was predicted by correlation between flank wear and cutting time, based on the extended Taylor tool life equation of turning data, including parameters of cutting speed, feed rate, and cutting depth. Secondly, each of cutting conditions of endmilling was equivalently converted to apply ball endmill data to the extended Taylor equation. The web-based reliability prediction program for tool life is being developed as one of reliability assessment programs to for the machine tools.

      • 객체 관계형 데이타베이스 관리 시스템을 이용한 디지털 앨범의 설계 및 구현

        이준서,장염승,한기준 건국대학교 산업기술연구원 2000 건국기술연구논문지 Vol.25 No.-

        As the storage capacity of a computer system is rapidly increasing and the cost of computer hardware is decreasing continuously, users can easily manage multimedia data on the personal computer. Especially, various image view programs are widely used to manage image files at the present time. However, since most of these programs do not use a database management system(DBMS), it is very difficult for users to use them efficiently. In this paper, we designed and implemented a Digital Album by using an object-relational database management system, called PARODY(Persistent, Almost, Relational Object Database sYstem) that implements a persistent object database with a relatively simple interface to its C++ class library. Since PARODY is used as a data storage manager of the Digital Album, users can manage(i.e., insert, update, and delete) an image database and search for the required image data from the image database easily. In addition, we use OWL(Object Windows Library) of Borland C++ to implement the user interface of the Digital Album efficiently.

      • KCI등재후보

        경옥고 및 경옥고 가미방이 폐암에 미치는 영향

        이은숙,서부일,이준우,배진숭 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2

        Objectives : This research is to test anti-cancer effect of kyungohkgo (sample 1) and modified kyungohkgoes (sample 2 and sample 3) when they prescribed to mice that translate a 3LL lung cancer cell. A sample 1, 2, and 3 are prescribed for the 1st, 2nd and 3rd group, respectively. Methods : Inoculate mouse lung carcinoma cells to a BDFI mouse and did an experiment about tumor occurrence periods, body weight, tumor volume, survival rate, life prolongation. Results : The development time of tumor lump to the 3rd group is latest as 181.71±18.88 hours. That is, it means that a lung cancer of this group was induced latest. In tumor size, the 3rd group is also fewest by 1,536~9,375㎣. The tumor growth rate of the 3rd group appeared lowest by 610.35 percent. Only the 3rd group was appeared that has a control effect of tumor growth. Also, 3 mice of the 3rd group were survived for 30day after translating the lung cancer cells. The survival extension rate of the 3rd group was highest by 38.39 percent. Conclusion : In these experiments, it appears that the sample 3 prescribed by modified kyungohkgo has the highest anti-cancer effect. It is proved that the modified kyungohkgo affects the 3LL lung cancer cell by acting complexly.

      • Silicone rubber 멤브레인을 이용한 압저항형 저차압센서의 개발

        서창택,공성수,심준환,고광락,서현미,김영진,설철규,신장규,이종현 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

        A 4-beam piezoresistive differential pressure sensor using a silicone rubber membrane has been fabricated on the selectively diffused (100)-oriented n/n^(+)/n silicon substrates by an unique silicon micromachining technique using porous silicon etching. The width, length, and thickness of the beam is 120 μn, 600 μm, and 6 μm, respectively, and the thickness of the silicone rubber membrane was 36 gm. By the use of four-beam structure, the mechanical strength of the differential pressure sensor can be highly improved due to smaller shear stress. And the lower sensitivity of the sensor can be simply solved by combining two output signals of half-bridge. The effectiveness of the sensor is confirmed through an experiment and FEM simulation in which the differential pressure sensor is characterized.

      • 암모니아 공정에서 CO₂ 고정의 최적화

        서성규,이정섭,송준석 國立麗水大學校 環境問題硏究所 2004 環境硏究論文集 Vol.6 No.-

        This study was investigated the effects of various system parameters on the absorption of carbon dioxide into absorption solution. An aqueous potassium carbonate solution was used as a chemical absorbent in order to figure out the effect of chemical reaction. For this purpose, the chemical analysis of potassium carbonate solution was performed. The changes of pressure, temperature, K₂CO₃solution flow/feed gas ratio and solution concentration in the absorber and the changes of pressure and temperature in the stripper were also analyzed. The analysis result shows that K₂CO₃ concentration in potassium carbonate solution was 99.6%. The optimum pressure was found to be 27.0㎏/㎠ and the optimum temperature was to be 68℃, the optimum concentration of potassium carbonate solution was to be 26.0wt% in the absorber. The CO₂ leakage decreased with the increment of the K₂CO₃ solution flow/feed gas ratio. But the H₂ leakage in the CO₂ product increased at or above the K₂CO₃ solution flow/feed gas ratio of 1.10. This H₂ leakage induced by the loss of ammonia production. The effects of the changes of the operation condition of the CO₂ stripper to the K₂CO₃ conversion are as follows. The K₂CO₃ conversion decreased as the pressure decreased. The K₂CO₃ conversion increased as the temperature increased. However, increasing the temperature without decreasing the pressure did not bring positive effect. The optimum pressure was found to be 0.45㎏/㎠.

      • KCI등재후보

        경옥고와 경옥고 가미방의 면역활성에 관한 연구

        이은숙,서부일,이준우,배진숭 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2

        Objectives : This study was conducted to investigate the immunological activities of Kyungohkgo and prescription of modified Kyungohkgo. Methods : Raw 264.7 macrophage treated with Kyungohkgo or other simuli enhanced production of the nitric oxide and TNF-α. Results : Among the sample 1. sample 2 and 3 of Kyungohkgo, sample 2 exerted more favorable influence on nitric oxide(NO) production than the sample 3. And production of NO and TNF-α were dependent on the concentration of Kyungohkgo. Conclusion : These results suggested that Kyungohkgo-activated macrophage induce the NO and TNF-α, and its containing in immunoregulatory components.

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