복부기형혈관의 문맥-체순환 단락으로 유발된 만성 후천성 간뇌 퇴행중 1례

김대현,김종국,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

농산물 소독과정에서 브롬화메틸에 노출된 근로자에게 발생한 신경병 2례

박태혁,김정일,손지언,김종국,김형수,정갑열,김준연 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.4

목적 : 농산물 소독과정에서 브롬화메틸에 노출된 근로자에게 발생한 신경병 2례 보고. 방법 : 피로감, 전신무력감, 어지럼증, 보행장애 등의 증상을 주소로 내원한 브롬화메틸을 사용하여 방역작업에 종사하는 건강한 20세와 18세의 근로자를 대상으로 혈액검사, 신경정도 및 근전도검사, 뇌자기공명영상 등의 임상검사와 작업력조사를 시행하였다. 결과 : 1례에서 뇌자기공명영상에서 연수와 소뇌의 양측 측충부의 고신호강도가 관찰되었고 11일 후의 추적조사에서 동일 부위의 고신호강토가 감소된 소견이 관찰되었으며 뇌병증으로 최종 진단되었다. 다른 1례는 신경전도검사에서 다발성 신경병 소견과 뇌유발전위검사에서 우측 하부 뇌간부위 병소가 관찰되었고 뇌병증 및 말초신경 병으로 최종 진단되었다. 결론 : 근로자들의 증상은 소독과정에서 브롬화메틸 노출로 인한 신경 병으로 판단되며 훈증소독과방역작업에 종사하는 근로자들의 실태조사와 안전에 대한 대책이 시급하다고 하겠다. Objectives : To report two cases of neuropathy due to methyl bromide intoxication. Methods : Workers, engaged in the fumigating process, complained fatigue, general weakness, ataxia, and hypersomnia. We evaluated them with blood tests, neurophysiologic studies and MRI and investigated their occupational history. Results : Increased signal intensities were found in the medulla oblongata and paraver mian of cerebellum in MRI and after 11 days, high signal intensities were reduced in the following MRI. In the other case, polyneuropathy and rlght lower brainstem lesion were observed In the NCV and BAEP studies. Conclusions : We confirmed that worker's symptoms were related to methyl bromide exposure in the fumigation. It is necessary that we should evaluate present condition of fumigating process and prepare appropriate methods to protect workers engaged in the fumigation.

위암 환자에서 세포성 면역 기능에 관한 연구

이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김삼용,김영건 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

We performed a variety of lymphocyte stimulation tests, delayed hypersensitivity skin tests, and enumeration of several lymphocyte subpopulations in 21 patients with gastric cancer who did not receive any form of anticancer therapy, and in 20 healthy controls. The gastric cancer patients had significantly decreased number and total score of positive reactions in delayed hypersensitivity skin tests compared with the healthy controls. The percent of CD_(4) positive lymphocytes in the gastric cancer patients was significantly decreased compared to the normal control subjects, but it had no correlation with the total score of delayed cutaneous hypersensitivity reactions. The ratio of helper to suppressor cells was lower in the cancer group. The uptake of 3H-thymidine was markedly depressed in cancer patients when stimulated with various mitogens. There was little correlation between any of the stimulation tests and any of the lymphocyte subpopulation proportions to delayed hypersensitivity cutaneous reactions. Optimal proliferative response was found in lymphocytes stimulated with 10 micrograms of concanavalin-A and 10 microgram of phytohemagglutinin. Advanced stage patients had greatly depressed delayed hypersensitivity skin reactions and proliferative responses to mitogens compared with localized diseases. These results suggest that gastric cancer patients have depressed cellular immune functions, which mainly result from the decreased helper cells and defects in functional proliferative response to mitogens. Interleukin-2 and interferon-gamma restored the in vitro proliferative response of lymphocyte in patients with gastric cancer.

위암 환자에게 세포성 면역 기능에 관한 연구

이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김상용,김영건 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1991 No.-

터보부호의 복호 알고리즘에 관한 연구

金鍾國,張涇秀,鄭夏奉 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

본 논문에서는 AWGN 채널 환경에서 MAP(Maximum A Posteriori) 알고리즘을 이용한 터보부호의 반복 복호시 패리티 정보 갱신을 추가하는 알고리즘을 제안하였다. 기존의 MAP 알고리즘을 이용한 터보 코드의 반복 복호 방법은 수신한 패리티 정보를 전혀 갱신하지 않은 상태에서 반복 복호를 수행하는 방법이지만 반복 복호시마다 패리티 정보를 갱신해 준다면 오류가 정정된 패리티 정보를 이용하기 때문에 복호 성능이 더 좋아질 것이라는 가정하에 모의 실험을 실시하였다. 새로운 알고리즘에서는 마지막 반복 복호 전 단계에서만 패리티 정보를 갱신해 주었고 기존의 MAP 알고리즘을 이용한 반복 복호 방법의 성능과 비교 분석하였다. In this paper, we investigated a new iterative decoding algorithm for Turbo codes, which exploits the extrinsic information about not only the information bits but also the parity-bits. In simulation, this additional extrinsic information is added at the final iterative stage. The simulation result shows very little perfoiniance enhancement.

액정 함유(W/O)/W 에멀젼형 액막을 이용한 LD-라세믹체 아미노산으로부터 L 및 D 아미노산의 추출분리

김종국,김우식,이병철 연세대학교 산업기술연구소 1993 논문집 Vol.25 No.1

The purpose of this study is to separate each L-and D-amino acid from the racemic mixture of amino acid. which is obtained in chemical synthesis, using the liquid emulison membrane containing cholesteric liquid crystal. The LEM containing cholesteric liquid crystal was made according to kinds of cholesteric liquid crystal. And the selectivity of pure optical amino acid was obtained by extracting L and D-phenylalanine relatively, using the LEM containing cholesteric liquid crystal. When the optical activity of liquid ?? has negative value, the selectivity of D-phenylalanine was greater than that of L-phenylalanine in non-equlibrium state. But the selectivity disapperared as the process appoaches the eqilibrium of extraction and stripping.

IEC 60300과 ISO 9000의 통합에 관한 연구

김종걸,김진국 한국경영과학회 2002 한국경영과학회 학술대회논문집 Vol.- No.1(1)

IEC60300의 국제 규격은 시간종속성 경영 시스템의 규격으로써 제 1부는 시간종속성 경영 프로그램, 제 2부는 시간종속성 프로그램 구성요소와 업무, 제 3부는 응용지침 표준의 13개의 규격으로 구성되어 있다. 이 규격은 제품의 초기 단계서부터 폐기 단계까지 수명주기 전 단계에 걸쳐 운영의 효율성, 시간, 비용의 제약 하에 위험을 최소화하고 안전성을 최적화하기 위한 지침을 제공한다. 본 연구에서는 현재 기업들이 기본적으로 적용하고 있는 경영 모델인 ISO 9000 시스템과 안전 설계를 위한 신뢰성 분야의 IEC 60300 시스템의 통합모형을 모색하고자 한다.

직접 황 회수공정에서 Ce_(1-x)Zr_(x)O₂촉매를 이용한 반응특성 연구 : H₂O 와 석탄가스의 영향 Effect of H₂O and Coal Gas

김봉석,이종대,전진혁,박노국,류시옥,이태진,김재창 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.2

본 연구는 직접 황 회수공정에서 H_(2)O와 석탄가스의 영향에 대해서 조사하였다. Ce_(0.8)Zr_(0.2)O_(2)촉매를 이용하여 H_(2)O가 반응에 미치는 영향을 조사한 결과, 산화제인 H_(2)O의 첨가에 의해 반응가스의 환원력이 저하됨을 알 수 있었다. CO/H_(2)O-TRP 실험을 통해서는 반응온도 영역에서 water gas shift 반응이 일어나는 것을 확인 할 수 있었고, H_(2)O의 재산화 실험으로부터 환원된 촉매가 H_(2)O에 의해 재산화 됨을 알 수 있었다. Ce_(0.8)Zr_(0.2)O_(2) 촉매하에서 석탄가스를 환원제로 사용하여 반응온도 (500℃), 공간속도(30,000 ㎖/g-catㆍh), [CO+H_(2)]/[SO_(2)] 몰비(2.5)의 반응조건에서 실험한 결과 최대 75.8%의 원소 황 수율을 얻을 수 있었다. 이는 환원제로 석탄가스를 이용함으로써 H_(2)O에 의한 부반응을 억제할 수 있었으며 경제적인 측면에서 유리하므로 공정기술의 실증화 가능성을 향상시킬 수 있음을 확인할 수 있었다. The effect of H₂O and coal gas on a direct sulfur recovery process using Ce_(1-x)Zr_(x)O₂ catalysts was investigated in this study. As the reducing power of reactants was lowered in the present of H₂O, the activity of catalysts decreased. Temperature programmed reduction experiments showed that a water gas shift reaction took place in the temperature range of this study and that the reduced catalyst was re-oxidized by H₂O. DSRP was carried out on Ce_(1-x)Zr_(x)O₂ catalysts using a coal gas as a reductant. Maximum 76.8% yield of elemental sulfur was obtained at 500℃ with a space velocity of 30,000㎖/g-cat·h and [CO+H₂]/[SO₂] ratio of 2.5. The side reaction by H₂O could be inhibited using a coal gas.

SO_2 제거반응에서 Ce_1-xZr_xO_2 촉매의 Ce/Zr 몰비에 따른 반응성 연구

김봉석,이종대,박노국,이태진 한국공업화학회 2003 응용화학 Vol.7 No.1

The catalytic reduction of S0_2 to elemental sulfur by CO over CezrO_2 was studied in this work. The Cezr0_2 catalysts were prepared with a change in Ce/Zr mole ratio (Ce_l-xZr_x0_2, x=1, 0.8, 0.5, 0.2, 0). We investigated reactivity of Ce_1- xZr_x0_2 in accordance with experimental conditions, such as reaction temperature, space velocity(GHSV). The Ce_0.8Zr_0.2O_2 and Ce_0.5Zr_0.5O_2 catalysts showed the S0_2 conversion of 93% and elemental sulfur selectivity of 98% at temperature above 425 ℃, superior reactivity than other catalysts, The cerium based catalysts with zirconium were improved oxygen mobility and degree of reduction Ce^4+. It is important to control mole ratio between Ce and Zr because of the surpassing oxygen mobility and degree of reduction Ce^4+.

성인 급성 백혈병의 치료에 관한 연구

김종완,장준,신승훈,윤일국,박철신,김삼용 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

19 adult ALL patients were treated with follwing regimens; VP regimen to 5 patients, VPA regimen to 4 patients, multi-drug combined intensive therapy of Hoelzer regimen to 10 patients. The results of therapy are as follows: 1. Complete remission occured in 3 patients on VP regimen(60%), 4 patients on VPA regimen (100%), 8 patients on Hoelzer regimen (80%), respectively, and overall complete remission rate was 78.9%. 2. Mean survival time of total patients was 13.8 months, and in complete remission group, it was 16.2 month, but in non-complete remission group, it was 1.8 month. 3. Factors favorable for complete remission were absence of organomegaly(P<0.05) and initial leukocyte count under 30,000/㎟(P<0.01), factors favorable for the survival duration were initial leukocyte count under 30,000/㎟(P<0.05) and remission within 4 weeks of treatment.(P<0.01). 4. Recurrence rate were 40% in VP regimen, 50% in VPA regimen, and 20% in Hoelzer regimen. 5. During the remission induction period, common side effects of chemotherapy were alopecia, nausea, vomiting, mucositis, and general weakness and it was severe in VPA regimen and Hoelzer reimen than in VP regimen. But no significant difference was noted between VPA regimen and Hoelzer regimen. From the above results, we could confirm the importance of multiple drug combined intensive chemotherapy of remission regimen and periodic reinduction chemotherapy.