서울시민의 수돗물 불소화에 대한 인식

장재연,조수남,윤제용 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

Public perception concerning water fluoridation and influencing factors were assessed. A mailing survey was conducted in 1999 with a representative sample of the general Seoul citizen (response rate=40.1%), who consisted of 1108 adults aged between 20 and 78. The data were analyzed using the chi-square test and structural equation modeling. 48.3% favored and 11.4% opposed water fluoridation while 40.5% were not certain. The contact on information about water fluoridation was the most significantly influencing factor on the perception concerning water fluoridation while experience of marriage, income and the perception of tap water were also significant. 52.8% expect governmental health authorities to take the decisions about water fluoridation.

염증이 있는 충수돌기의 초음파 진단 : 자가 위치선정법의 정확도 Accuracy of Self-localization Technique

장현정,임효근,김승훈,이민희,윤지영,김경아,임재훈,정연권 대한초음파의학회 1998 ULTRASONOGRAPHY Vol.17 No.4

부하순환 하에서 제V급 복합레진 수복물의 미세변연누출에 대한 재접착제의 효과에 관한 연구

윤연희,김영재,김정욱,장기택,이상훈,김종철,한세현 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

저점도의 레진을 복합레진 수복물 위에 도포하는 것은 미세누출방지와 변연 완전성(integrity) 유지를 위한 한 방법이다. 하지만 장기간 관찰하면, 수복물은 저작압에 의한 영향을 받게 되는데, 저점도의 레진으로 수복물 변연부를 재접착(rebonding)하였을 때 저작압에 의한 응력에 견디면서 계속하여 수복물에 긍정적인 영향을 주는지에 대한 연구는 미흡한 실정이다. 본 연구는 부하순환(load cycling) 하에서 제Ⅴ급 수복물의 미세변연누출에 대한 재접착제 (rebonding agent)의 효과를 알아보고자 하였다. 40개의 건전한 소구치의 협면에 제Ⅴ급 와동을 형성하고 제조사의 지시대로 광중합복합레진으로 수복하였다. 20개씩 무작위로 나누어 표면전색을 하지 않는 Ⅰ군과 표면을 산부식 후 재접착한 Ⅱ군으로 설정하였다. 열순환 후 각 군에서 10개씩의 하위군 (A군=No load cycling군, B군=Load cycling군)으로 나누어 이중 B군의 시편에 1 Hz의 속도로 수직력이 4-100까지 100,000회의 부하순환을 가하였다. methylene blue용액에 침윤시켜 변연의 미세누출릉도를 평가하여 다음과 같은 결과를 얻었다. 1. 교합변연에서는 재접착과 무관하게 유의한 차이가 없었다(ⅠA-ⅡA군, ⅠB-ⅡB군) (p>0.05). 2. 치은변연의 경우는 부하순환을 하지 않은 군의 경우 재접착을 한 군(ⅡA군)이 재접착을 하지 않은 군 (ⅠA군)에 비해 더 적은 미세누출결과를 보였다(p<0.05). 3. 치은 변연에서 부하순환을 시행한 군의 경우에는 재접착을 한 군(ⅡB군)과 재접착을 하지 않은 군 (ⅠB군)과 유의차가 없는 비슷한 미세누출의 결과를 보였다(p>0.05). One clinical technique recommended f3r improving marginal integrity is "rebonding" or application of unfilled resins to the surface of composite restoration. But continuously the restorations are affected with occlusal load. There is room for doubt that the rebonding agent has the positive effect on microleakage in spite of the stress generated by the occlusal load. This study determined the effect of rebonding on microleakage of Class Ⅴ resin composite restorations under load cycling. Class Ⅴ cavities were prepared on the buccal surface of 40 sound extracted premolars and restored with a hybrid light-cured resin composite according to manufacturers' directions. They wert randomly divided into two groups consisting of 20 samples a control(group Ⅰ), without surface sealing, and the other group (group Ⅱ) in which margins were etched and rebonded. After thermocycling, each of groups was divided into subgroups (group A, B), and load cycling(total 100,000 cycles with 4-100N load at a rate of 1 Hz) were applied on the group B. Assessment of microleakage utilized methylene blue dye penetration. The following results were obtained : 1. In the occlusal region, no significant difference was noted in the scores regardless of whether or not the rebonding agent was used (group ⅠA-ⅡA, ⅠB-ⅡB) (p>0.05). 2. In the cervical region, the control group with rebonding (group ⅡA) showed the better result than the group without rebonding (group ⅠA) (p<0.05). 3. In the cervical region, the rebonded group with load cycling(group ⅡB) showed similar results to the groupf·ithout rebonding(group ⅠB) and no significant difference was noted(p>0.05).

MDVP와 Praat, Dr. Speech간의 음향학적 측정치에 관한 상관연구

유재연,정옥란,장태염,고도홍 한국음성과학회 2003 음성과학 Vol.10 No.3

The purpose of this study was to conduct a correlational analysis among Fo, Jitter, Shimmer, and NHR(HNR), and NNE estimated by three speech analysis softwares, MDVP, Praat and Dr, Speech. Thirty females and 15 males with normal voice participated in the study. We used Sound Forge 6.0 to record their voice. MDVP, Praat and Dr. Speech were used to measure the acoustic parameters. The Pearson correlation coefficient was determined through a statistical analysis. The results came out as follows: Firstly, there was a strong correlation between Fo and Shimmer of both instruments. However, there was no correlation between Jitter of both instruments. Secondly, Shimmer showed a stronger correlation with HNR, NHR, and NNE than Jitter. Therefore, Shimmer was considered to be more useful and sensitive parameter to identify dysphonic voice compared to Jitter.

Wiskott-Aldrich 증후군 환아의 증례보고

이연주,현홍근,장철호,김영재,김정욱,장기택,김종철,한세현,이상훈 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.3

자가 탈회골의 조직반응에 관한 실험적 연구

김장연,김영조,엄인웅,이동근,이재은 大韓顎顔面成形再建外科學會 1993 Maxillofacial Plastic Reconstructive Surgery Vol.15 No.3

Many surgeons are on the point of bone excision and reconstruction of the bone defects by autograft. xenograft, and allograft in the treatment fo begin and malignant tumors of bone. Of all type of bone grafts, we received the autograft as the best ideal bone graft. Of autogenic bone graft, replantation of excised autogenic bone for reconstructiong the bone defects has been the ideal method until now, but early bone healing reponses and tumor cell devitalization after replantation of excised autogenic bone have not been identified for clinical applications. So, to evaluate bone healing response after replantation in rabbit's calvarial bone, we divided the experimental group into three groups. Group 1 is a fresh autogenous bone group. Group 2 is a deep frozen group. Group 3 is freeze-dried demineralized group. Obtained result were as followed: 1. Inflammatory cell infiltration appeared at I week and disappeared at 4 weeks in all experimental group, Especially, severe inflammatory cell infiltration showed in fresh autogenous bone group at 2 weeks, Especially, severe inflammatory cell infitration showed n fresh autogenous bone group at 2 week Group 3 is the least showing group on the point of inflammatory cell infiltration. 2. Osteoblastic activity evenly increased upto 4 weeks and maintained to 6 weeks and decreased after this period, especially osteoblastic activity in group 2 is less than group 1 and group 3. We can't discriminate between osteoblastic activity of group 1 and that of group 3. 3. In new bone formation, group 3 was more active than any other groups at early stage, but there were little differences among three experimental groups at later state. 4. Bone resorption around the grafted bone slightly appeared at 1 week and disappeared at 4 weeks in all experimental groups. We can find the more bone resorption in group 2 at 2 weeks than any other groups. We could suggest, as appears from our results, that freeze-dried deminiralized bone graft is the useful bone graft in the clinical applications of excised autogenic bone.

생약추출물 유도형 Nitric Oxide Synthase 저해활성 검색

류재하,이소영,박재현,이화진,장세란,은진희,김남이,정연수,장미경,최영은,이숙현,손행자,안한나,고혜진 숙명여자대학교 약학연구소 2001 약학논문집-숙명여자대학교 Vol.17 No.-

Nitric Oxide (NO), derived from L-arginine, is produced by two types (constitutive and inducible) of nitric oxide synthase (NOS: cNOS and iNOS). The NO produced in large amounts by the iNOS is known to be responsible for the vasodilation and hypotension observed in septic shock and inflammation. The inhibitors of iNOS, thus, may be useful candidate for the treatment of inflammatory diseases accompanied by the overproduction of NO. We prepared alcoholic extracts of herbal drugs which have been used for the treatment of inflammation in oriental medicine. We have screened the inhibitory activity of NO production in lipopolysaccharide (LPS)-activated macrophages after the treatment of these extracts. Among the 81 kinds of extracts of herbal drugs, 34 extracts showed potent inhibitory activity of NO production above 50% at the concentration of 50 (μg/ml. The inhibitory activities of NO production were also evaluated for several solvent fractions at three different concentrations. Especially, hexane soluble fractions of Agrimonia pilosa, Hydrangea serrata, Machilus thunbergii, Prunella vulgaris, Saussurea lappa, Tussilago farfara, and ethyl acetate soluble fractions of Angelica gigas, Ostericum koreanum, Torilis japonica, Perilla frutescence showed moderate activity at 10 and/ or 25 (μg/ml. These fractions are promising candidates for the study of the activity-guided chromatographic purification of active compounds.

디지털 치료기술 산업 육성에 따른 투자와 경제적 파급효과

김재현 ( Jae-hyun Kim ),문종윤 ( Jong Youn Moon ),장지은 ( Jieun Jang ),심정연 ( Jung Yeon Sim ),신재용 ( Jaeyong Shin ) 한국보건행정학회 2020 보건행정학회지 Vol.30 No.4

The digital treatment technology industry is one of the core fostering industries of the Moon Jae-in government along with the global trend. The purpose of this study is to compare and analyze the investment and economic ripple effect on the related industries. To this end, we used the industry-related table, which is the actual measurement data for 2015 that the Bank of Korea actually measured and released every 5 years in 2019. The digital treatment technology industry was not clearly classified within Korea’s industrial classification system, so the contents of the industry-related survey were analyzed, and the digital treatment technology industry was reclassified and then analyzed. As a result of the analysis, it was analyzed that the production induction effect of the digital treatment technology-related industry in 2015 was 1.770, the value-added induction effect was 0.875, and the employment induction effect was 19.128, which was higher than that of other industries in Korea. As a result of the analysis of the economic ripple effect (scenario 1), the production inducing effect was about 370 billion won, the added value inducing effect was about 185 billion won, and the employment inducing effect was 4,044 people. The results of this study are expected to play a large role in economic revitalization as the effect of inducing production, increasing employment, and creating added value through fostering the digital treatment technology industry is expected to play a large role in activating the economy. It is expected to play a large role in providing central medical services. Therefore, it is expected that policy support for revitalizing the digital treatment technology industry through active investment support and tax benefits from the government to foster the digital treatment technology industry is necessary.

디메칠포름아미드에 의한 간기능 장해에 관한 연구

강성규,장재연,이경용,정호근 大韓産業醫學會 1991 대한직업환경의학회지 Vol.3 No.1

To investigate the liver dysfunction among workers exposed to dimethylformamide, 24 workers were examined on the liver transaminases and the urine metabolite. The results were as follows: 1. Nine of 24 workers examined had abnormal values in serum aspartate aminotransferase(AST), 5 in serum alanine aminotransferase (ALT), 1 in Υ-glutamyl transferase(Υ-GT). The possibilties of hepatitis due to other causes were excluded by the viral serologic tests and other results. 2. The urinary excretion values of N-methylformamide(NMF), metabolite of dimethylformamide(DMF) were over biological exposure index(BEI) in 4 of 24 workers. 3. The air concentration of dimethylformamide was over threshold limit values(TLV-TWA) in 1 of 5 workers sampled by personal air sampler. 4. The correlation coefficients between age, working part and the values of liver transaminases were not statistically significant.

1,2,4-트리메틸벤젠에 피폭된 노동자의 뇨 중 3,4-디메틸히푸르 산과 크레아티닌의 정량

임정미,장재연,이용문,강종성 충남대학교 약학대학 의약품개발연구소 1997 藥學論文集 Vol.13 No.-

Creatinine and 3.4-Dimethylhippuric acid (3.4-DMHA), a glycine conjugate of 1.2.4-trimethylbenzene (1.2.4-TMB) were determined in the urine of workers exposed to 1.2.4-TMB vapor. The best condition for the simultaneous determination of 3.4-DMHA and creatinine by high performance liquid chromatography was obtained by reverse phase C-18 column (4.6×150㎜, 5㎛) as stationary phase and 20% acetonitrile in 20mM phosphate buffer (pH 3.0) containing 4mM sodium octylsulfate (SOS) 96%. The concentration of urinary 3.4-DMHA of workers had a positive correlation with the environmental level of 1.2.4-TMB(r=0.866). The data suggest that urinary 3.4-DMHA concentration is a useful biological index for 1.2.4-TMB exposure.