천식 소아에서 혈중 포스포리파제 A2: leptin과 운동유발 기관지과민성과의 상관성

유정섭 ( Jueng Sup You ),최원복 ( Won Bok Choi ),이윤영 ( Yoon Young Yi ),정수인 ( Soo In Jeong ),송준섭 ( Joon Sup Song ),양승 ( Seong Yang ),황일태 ( Il Tae Hwang ),이하백 ( Ha Baik Lee ),백혜성 ( Hey Sung Baek ) 대한천식알레르기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.2

Purpose: Dysregulated cysteinyl leukotriene (CysLT) synthesis is prominent in exercise-induced bronchoconstriction (EIB). Secreted phospholipase A2 (sPLA2) plays a key regulatory role in the biosynthesis of CysLTs. We previously found that serum leptin levels cor￢relate with (EIB) in children with asthma. The aim of this study was to address the relationship between plasma sPLA2/leptin levels and EIB. Methods: Sixty-seven prepubertal children between the ages of 6 and 10 years were included in the study. They were asthmatics with EIB (n=25), asthmatics without EIB (n=21), and healthy subjects (n=21). We measured the plasma sPLA2 and leptin levels. We also performed pulmonary function tests at baseline, after bronchodilator inhalation, and after exercise. Results: The sPLA2 and leptin levels were significantly higher in asthmatics with EIB than in those without and control subjects. In addition, sPLA2 levels were significantly correlated with body mass index (Speraman correlation coefficient r=0.343, P=0.023) and leptin levels (partial correlation coefficient r=318, P=0.033). The maximum decrease in % forced expiratory volume in 1 second af￢ter exercise was significantly correlated with both PLA2 levels (r=0.301, P=0.041) and leptin levels (r=0.346, P=0.018). Conclusion: The sPLA2 and leptin levels were significantly higher in asthmatics with EIB than in asthmatics without EIB and control subjects. In addition, sPLA2 levels were significantly correlated with leptin levels and EIB in asthmatic children.(Allergy Asthma Respir Dis 2015;3:99-104)

Thermal Properties of Copolyetherester/silica Nanocomposites

Baik, Doo-Hyun,Kim, Hae-Young,Kwon, Sun-Jin,Kwon, Myung-Hyun,Lee, Han-Sup,Youk, Ji-Ho,Seo, Seung-Won The Korean Fiber Society 2006 Fibers and polymers Vol.7 No.4

Thermal properties of copolyetherester/silica nanocomposites were examined by using DSC and TGA. The segmented block copolyetheresters with various hard segment structures and hard segment contents (HSC) were synthesized and their silica nanocomposite films were prepared by solution casting method. The nano-sized fumed silica particles were found to act as a nucleating agent of the copolyetheresters. The nanocomposites always showed reduced degree of supercooling or faster crystallization than the corresponding copolyetheresters. The nanocomposites also showed increased hard segment crystallinity except HSC 35 sample which had short hard segment length. In case of 2GT [poly(ethylene terephthalate)] copolyetheresters, which were not developed commercially because of their low crystallization rate, the hard segment crystallinity increased considerably. The copolyetherester/silica nanocomposites showed better thermal stability than copolyetheresters.

초등학생 태권체조 참여도가 학교생활적응에 미치는 영향

백남섭,지동철,강은정 龍仁大學校 武道硏究所 2011 武道硏究所誌 Vol.22 No.1

이 연구의 목적은 초등학생 태권체조 참여도가 학교생활적응에 미치는 영향을 규명하는데 그 목적이 있다. 이는 상관관계 분석과 다중회기분석을 실시하여 개인적 특성에 따른 태권체조 참여도, 학교생활적응의 차이와 태권체조 참여도와 학교생활적응의 관계에 대하여 결과를 얻었다. 검사자료의 분석 결과는 다음과 같다. 첫째, 개인적 특성인 성별, 학년, 수련기간, 주 수련횟수, 주 수련기간에 따른 태권체조 참여도의 차이분석에서는 주 수련시간이 진지형에 유의한 영향을 미쳤으며, 성별, 학년, 주 수련횟수가 기피하는 유형에 영향을 주었지만 성별, 학년, 수련기간, 주 수련횟수, 주 수련기간이 태권체조참여의 하위요인 진지형에는 영향을 주지 않았다. 둘째, 개인적 특성인 성별 학년, 수련기간, 주 수련횟수, 주 수련기간에 따른 학교생활적응의 차이분석에서는 학년, 수련기간, 주 수련횟수가 교사관계에서 좋은 영향을 미쳤으며, 또한 학년 수련기간이 교우관계에서도 좋은 영향을 미쳤으며, 성별, 학년, 수련기간이 학교수업에 긍정적인 성향을 띄었으며, 수련기간에 따른 학교규칙을 잘지킨다는 연구 결과가 나타났다. 셋째, 초등학생 태권체조 참여도가 학교생활적응에 어떠한 영향을 미치는 지를 알아보기 위한 결과로 진지형은 교사관계, 교우관계, 학교수업, 학교규칙에서 긍정적인 영향을 준다는 연구결과가 나타났지만, 의무형에서는 교사관계, 교우관계, 학교수업, 학교규칙 모두 영향을 미치지 않는 것으로 나타났다. 또한 기피형에서는 교사관계, 교우관계, 학교수업, 학교규칙 모두 영향을 미치지 않는 것으로 나타났다.

B 형 급성간염에서 IgM Anti-HBc 의 진단적 의의

백승호,조성원,심찬섭,윤석중,나우균,박노춘 대한내과학회 1987 대한내과학회지 Vol.32 No.3

To investigate the diagnostic significance of IgM anti-HBc in acute hepatitis B, IgM anti-HBc was measured by radioimmunoassay in 41 pateitns with acute hepatitis B, 18 patients with chronic hepatitis, 29 patients with liver cirrhosis, 1S patients with primary hepatoma, and 23 healthy carriers. The results obtained were as follows; 1) Distribution of Hepatitis B virus markers in acute hepatitis B Of the 41 patients with acute hepatitis B, 29 patients (70.8%) were seropositive for HBsAg and IgM anti-HBc, 6 patients (14.6%) were seropositive for HBsAg and seronegative for IgM anti-HBc, 5 patients (12.2%) were seronegative for HBsAg and serapositive for IgM anti-HBc, and 1 patient (2.4%) was seronegative for HBsAg and IgM anti-HBc. 2) IgM anti-HBc in acute hepatitis B Of the 41 patients with acute hepatitis B, 34 patients (82.9%) were IgM anti-HBc positive. IgM anti-HBc was tested in 33 patients with positive IgM anti-HBc within 2 weeks after onset of jaundice, and tested in 7 patients with negative IgM anti-HBc more than 4 weeks after onset of jaundice. IgM anti-HBc titer decreased gradually with time in 12 patients with positive IgM anti-HBc in whom the follow up evaluation was available. In 3 patients, IgM anti-HBc became negative seroconversion at 4 weeks after onset of jaundice, In 3 patients, IgM anti-HBc became negative seroconversion at 9 weeks, 11 weeks, and 20 weeks after onset of jaundice, respectively. IgM anti-HBc was more frequently detected in acute hepatitis B compared with chronic liver diseases (p$lt;0.05) and 23 of 41 patients (56.1%) with acute hepatitis B had P/N ratio over 4. 3) IgM anti-HBc in chronic liver disease IgM anti-HBc was postitive in 2 of 1S patients (11.1%) with chronic hepatitis B, 5 of 29 patients (17.2%) with liver cirrhosis, 3 of 18 patients (~26.7%) with hepatoma, and 1 of 23 (4.3%) healthy carriers. Among these, only 2 patients (7%) with liver cirrhosis had P/N ratio over 4. 4) The relationship between HBeAg and IgM anti-HBc in acute hepatitis B There was no significant difference in positivity and P/N ratio of IgM anti-HBc between HBeAg positive and negative patients with acute hepatitis B(p$lt;0.1), In conclusion, IgM anti-HBc testing can aid in the diagnosis of acute hepatitis 8. But if IgM anti-HBc testing is performed more than 4 weeks after onset of jaundice, it could be negative in acute hepatitis B. And it should be careful to diagnose acute hepatitis B because there is false negative results on conventional radioimmunoassay in acute hepatitis B.

Acupuncture Meridian and Intravascular Bonghan Duct

Baik, Ku Youn,Lee, Ja Woong,Lee, Byung Cheon,Johng, Hyeon Min,Nam, Tae Jeong,Sung, Baeckkyoung,Cho, Sung Il,Soh, Kwang Sup Trans Tech Publications, Ltd. 2005 Key Engineering Materials Vol.277 No.-

<P>Current anatomical theory does not recognize the existence of an extended floating threadlike structure inside the blood vessels. Nonetheless, this study developed a new method for observing such an intravascular threadlike structure. The key technique involves injecting acridineorange into the femoral vein to circulate along the blood vessels and stain the nuclei of the intravascular threads inside the blood vessels. In-situ observations were then made under a fluorescence stereomicroscope after saline-perfusion. Confocal microscope images revealed a distinctive characteristic pattern of nucleus distribution that was clearly distinguishable from fibrin, capillaries, small venules, arterioles, or lymph vessels. Accordingly, it is suggested that the identified intravascular threads are part of the Bonghan's circulatory network that is distributed throughout the body, including inside the blood vessels.</P>

한국의 발톱진균증 환자의 삶의 질에 관한 연구

조백기,박종갑,김형옥,김성욱,백승철,김진우,김시용,안규중,전재복,오지원,김낙인,이규석,오칠환,김수남,김상태,손숙자,신용우,김동석,이원우,권경술,서대헌,황규왕,이종석,고재경,강원형,정기양,최응호,김기홍,박석돈,강승주,함정희,명기범,김방순,구상완,김병수,원영호,김한욱,송은섭,정병수,노병인,홍창권,박장규,한지윤,김광중,구대원,김종민,김재홍,유희준,양경미 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2

Background: Onychomycosis, especially toenail onychomycosis has become one of the common fungal infection and has historically been regarded as a cosmetic rather than medical problem by many patients, even by physicians. Recently, however, there are several reports that is a refractory disease which may cause a deleterious effect on patiets quality of life (QOL). Objective: The purpose of this study was to investigate the impact of toenail onychomycosis on QOL in Korea and to assess the chandes of QOL after treatment. Methods: Total 1004 patients with toenail onychomycosis which was confirmed by clinical findings and KOH preparation were were enrolled at 47 dermatologic centers in Korea, and interviewed with standardized QOL questionnaire before and after sytemic antifungal treatment. Responses to the questionnaire were scored by 5-point scale (1∼4) and averaged, and were analyzed for 5 dimensions of emotional impact, social impact, symptorn and functional impact, patients views concerning treatment, and relationship with doctor. Results: 1. Before and after treatment, the most serious impact was emotional dimension showing 1.90 and 1.30 in average score (AS), and social (AS: 1.14 and 0.83) and symptom and functional impact (AS: 1.05 and 0.92) was also affected. 2. In female rather than male, statistically more significant impact on patients QOL was observed in all dimensions. 3. After treatment, 3 of 5 dimensions were improved significantly - emotional dimension (AS : from 1.90 to 1.30), social dimension (AS: from 1.14 to 0.83), patients view concerning treatment (AS: from 1.34 to 1.02). 4. The drgree of patients satisfaction at the therapeutic effect was very high- 62.4% (immediately after treatment) and 65.8% (9 months affer initiation of treatment) of patients answered excellent or good. Conclusion: This study confirms that toenail onychomycosis has significant impact on the overall QOL of patients. Also the effect of antifungal therapy on patients QOL were watisfactory. Therefore, both doctor and patient should pay more attention to the treatment of onychomycosis. [Kor J Med Mycol 3(1): 115∼124]

Establishment of the Measurement System of the Magnetic Field for the Study on the Magnetic Field Tolerance of TMP

Kyungmin Baik,Wan-Sup Cheung,Jong-Yeon Lim,Choi Kyoung-Min,Nam Seung-Hwan 한국진공학회 2013 한국진공학회 학술발표회초록집 Vol.2013 No.8

Pico-meter Metrology: Challenges in Vibration Calibration and Measurement

Wan-Sup Cheung(정완섭),Kyungmin Baik(백경민) 한국소음진동공학회 2015 한국소음진동공학회 학술대회논문집 Vol.2015 No.10

Fabrication of a Circular Coil for the Study on the Magnetic Field Tolerance of TMP

Kyungmin Baik,Wan-Sup Cheung,Jong-Yeon Lim 한국진공학회 2013 한국진공학회 학술발표회초록집 Vol.2013 No.2

자동차 배기정화용 촉매에 관한 연구 : 자동차 배기가스중 탄화수소의 산화 반응 Oxideation Reaction of Hydrocarbons in Automative Exhaust Gases

河伯顯,金冕燮 漢陽大學校環境科學硏究所 1981 環境科學論文集 Vol.2 No.-

백금-알루미나촉매, 백금-알루미나-제올라이트Y촉매 그리고 제네랄모타제촉매를 사용하여 배기가스내 탄화수소의 각 성분별 산화활성을 측정하고 사용시간에 따른 촉매의 변화를 주사현미경으로 관찰하였다. 배기가스중 탄화수소의 성분은 약 10종으로 분리확인되었으며 이들 성분의 조성은 대략 C₁∼C₄10%, ??∼?? 71% 및 ??∼?? 19%의 분포로 나타났다. 탄화수소의 산화활성 측정결과, 백금-알루미나-제올라이트Y촉매가 다른 두개의 촉매보다 초기활성이 크고 활성저하에 대한 저항도 우수하였으며 탄소수가 적은것 C₁∼C₄과 큰 것(??∼??)의 산화활성이 컷다. 주사현미경에 의한, 사용한 촉매의 변화를 조사한 결과, 900℃에서 전처리된 백금-알루미나 촉매는 반응온도 900℃ 이하에서는 산화반응으로 인한 구조변화는 크게 일어나지 않았다. 또한 500℃에서 전처리된 백금-알루미나-제올라이트Y촉매는 산화반응으로 인하여는 제올라이트 구조에는 변화가 없었으나 혼제하고 있는 알루미나는 소결이 일어남을 알았다. The individual oxidation activity of each hydrocarbon components in the exhaust gas on platinum-alumina, platinum-alumina-zeolity and on General Motor catalyst were measured. Morphological change on the catalyst surgace after oxidation reaction were observed by scanning microscope. About 10 kinds of hydrocarbon showed that the composition were ranged 10% for C₁∼C₄71% for ??∼?? and 19% for ??∼?? on the average. It was found that the platinum-alumina-zeolite Y catalyst was superior to the others both in initial activity andsin resistance for contamination degradation, and had a higher oxidation activity particularly for hydrocarbons having lower molecular weight (C₁∼C₄)and for higher (??∼??). Examination of the scanning electron micrographs for the used catalysts revealed no significant morphological change below reaction temperature 900℃ on the alumina catalyst pretreated at 900℃, while on the platinum-alumina-zeolite Y pretreated at 500℃, it was observed that zeolite particle embeded in alumina matrix was not changed bot the alumina itself was partially sintered.