생물학적 및 미생물전기화학적 수소 메탄화

권혜정, 박준규, 전항배 충북대학교 산업과학기술연구소 2018 산업과학기술연구 논문집 Vol.32 No.2

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안경착용자의 안경착용에 대한 이미지 연구 : Q-방법론적 연구 Q-methodological Approach

정수정,정혜경,김경희,권혜진 韓國學校保健學會 1999 韓國學校保健學會誌 Vol.12 No.1

This study attempts to identify the self-image of eyeglass wearers with Q-methodology. Preliminary Q-statements were collected through personal and telephone interviews and based in consultation with reference books, eyeglass wearers, an optician and an oculist. Finally,34 Q-samples were seleted. The results were analyzed by a Q-factor with a PC QUANL Program. The sell-image of eyeglass wearers were found to revolve around three types: Type 1. They feel that eyeglasses have a negative inf1uence on image and that they uncomfortable. In addition, other people have a negative bias toward people who wear eyeglasses. As a result of these negative prejudices and inconveniences, there is a tendency to wear contact lens or have laser operations. Type 2. They feel less uncomfortable comparatively', when explained that classes can help improve their image. When explained as a fashion accessory, negative prejudices almost disappeared. Type 3. They show a positive reaction when explained that spectacles are also rosed for sight protection. However, they are sensitive to changes in their complexion as a result of eyeglass wear and place much importance in the design of glass frames. The significance of this study is to suggest basic data for a mediation device that improve the image of eyeglass wearers discovery and analysis of these three types.

발달지체인의 자기 결정 : 교육적 접근과 가족 참여 Instructional Approaches and Family Involvements

김정권,김혜경 국립특수교육원 2000 특수교육연구 Vol.7 No.-

본 연구는 발달지체인의 삶과 교육의 질에 관한 담론으로서 자기 결정 능력 신장을 위한 교육 전략과 가족 참여의 의미를 밝히고자 하는 것이다. 탈 현대성에 비추어 볼 때, 자기 결정은 발달지체인의 질적 삶과 완전 사회 및 교육 통합을 성취하기 위한 기본적인 요소이며, 발달지체인이 완전한 시민으로서 살아가기 위한 심리적 행동의 기본 요소라고 볼 수 있다. 그러므로 자기 결정 능력은 특수 교육에서 중요한 교육의 성취 과제로 인정이 되어야 하며, 이를 위해 교수 전략을 발전시켜야 한다. 또한 발달지체인의 자기 결정 신장을 위해서는 모델링이나 부모와 자식 간의 상호 작용 등과 같은 가족의 역할이 아주 중요하다고 할 수 있다. The purpose of this study is to explore strategies of instructional approaches and family involvement for the development of self-determination in people with developmental disabilities. The concrete purposes are to clarify (1) meaning of developmental disabilities's self-determination, which is based on the paradigm of post-modernity (2) instructional approaches to develop self-determination ability of developmental disabilities (3) importance of family involvement to develop self-determination ability of developmental disabilities. The conclusions of this study are followed. First, self-determination of developmental disabilities is basic elements to achieve quality of life and full-inclusion, which is based on the paradigm of post-modernity. Second, self-determination is essential educational achievement in special education. Instructional strategies for self-determination ability are teaching within the context of daily routines, positive behavioral supports, incidental teaching, engagement, communication technology, social competence, and activity instruction. Third, family involvement is highly important for the development and expressions of self-determination in people with developmental disabilities. Parents play a critical role in the development of self-determination in two key ways : (1) as models of self-determined behavior for their sons and daughters, and (2) by interacting with their sons and daughters in ways that promote self-determination.

정맥주입 전문간호사가 삽입한 말초삽입형 중심정맥관(PICC) 사용 결과에 대한 후향적 분석

박정윤,박광옥,백미경,김세라,권혜리,양수진 대한기초간호자연과학회 2004 Journal of korean biological nursing science Vol.6 No.1

Background : Intravenous(Ⅳ) access is becoming an increasingly important part of health care today. The current drive for clinical effectiveness and cost-effective health care serves to increase the need for reliable vascular access. Venous access devices were developed to overcome problems associated with limited peripheral access and frequent venipuncture in patients with long-term therapy. Although the peripherally inserted central catheter(PICC) have become popular during recent years in USA, its procedure is rare in Korea. Purpose : The goal of this study was to analyze the PICC inserted patient data by Ⅳ CNS intervention. Method : A Total of 62 PICCs were inserted into 51 patients by the Ⅳ CNS during a 10-month period form November, 14, 2002, to October 2, 2W2. Data was obtained retrospectively through chart review. Result : The patient population included 34(54.8%) men and 28(45.2%) women, with a mean age 50.6 years. The main indication for PICC placement was to access vein in poor peripheral venous status(40.3%). The mean served interval for PICC insertions was 16.7 days(range, 2~61 days). The reasons for removal were completed therapy in 18 cases(29.0%), patient death in 13 cases(21.0%), and mechanical or functional PICC problem in 10cases(16.1%). The three PICCs removed for presumed infection, and one had only positive tip cultures(0.2%). Conclusion : PICCs are rapidly growing popularity and required an extended course of Ⅳ therapy.

일개 제빵회사 근로자의 제빵공 천식 유병률

김정민,권영준,주영수,임형준,이태경,강혜련,백도명 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.3

목적: 일개 제빵회사에서 제빵공 천식 유병률을 조사하여 제빵공 천식으로 인한 국내 질병부담을 파악하는데 기초자료를 제공하고자 하였다. 방법: 일개 제빵회사의 생산관련 근로자 596명에서 수습기간(3개월) 중이거나 참여를 거부한 216명을 제외하고,380명을 연구대상으로 하였다. 밀가루분진 노출형태에 따라 직접노출군과 간접노출군으로 직무 카테고리를 분류하고,설문조사는 ISAAC 설문항목에 직업력 등을 추가한 설문지를 사용하였다. 설문조사에서 천식이나 알레르기병과 관련된 증상이나 병력이 전혀 없는 간접노출군은 임상검사대상에서 제외하였다. 임상검사대상 233명에게 피부단자검사,혈청 특이 IgE 항체검사,산업의학 전문의와의 면담을 시행하였고,면담에서 천식이나 알레르기비염과 관련된 증상이나 병력이 확인된 31명을 연속적 PEFR 측정대상으로 하였다. PEFR 변동률로써 메타콜린 기관지유발검사대상을 선정하였고,메타콜린 기관 지유발검사에서 기관지과민성이 확인된 경우에 특이 기관지유발검사를 시행하였다. 제빵공 천식은 특이 기관지유 발검사에서 천식반응이 확인된 경우로 정의하였다. 결과: 연구대상의 밀가루 민감화율은 21.0%(직접노출군 25.9%,간접노출군 13.3%), 제빵공 천식 유병률은 3.2%(직접노출군 5.1%,간접노출군 1.8%)였다. 직접 노출군이 간접노출군에 비해 밀가루에 민감화될 위험이 높았으며(OR 2.15,95% CI=1.03∼4.51), 제빵공 천식에 이환될 위험은 통계적으로 유의하지 않았다(PR 2.52,95% CI=O.78∼8.18). 밀가루에 민감화된 군이 그렇지 않은 군에 비해 제빵공 천식에 이환될 위험이 매우 높았다(PR 38.63, 95% CI=6.14∼243.22). 결론: 이번 연구결과는 직업적으로 밀가루에 노출되는 국내 근로자에서 제빵공 천식이 적지 않을 것임을 시사하고 있다. 향후 제빵공 천식으로 인한 질병부담을 보다 정확히 파악하기 위해서는 국내에서 연구된 바 없는 밀가루 취급 사업장(제분회사 등)에 대한 연구가 필요하며,근로자의 건강과 사회경제적 위치를 보호하기 위한 체계적인 연구도 요구된다. Objectives: To determine the prevalence of baker's asthma due to flour dust in an industrial bakery in Korea. Methods: Of the 596 active workers, 380 were allocated to a category of either direct exposure (DE) or indirect exposure (IE) to flour dust and completed a modified ISAAC questionnaire. Of the 380 participants, 233 were screened by an occupational physician interview, a skin prick test, and an ELISA for serum-specific IgE antibodies to wheat flour extracts. Selected workers received serial monitoring of peak expiratory flow rate (PEFR), and positive PEFR respondents received a methacholine challenge test. The diagnosis of baker's asthma was confirmed by a specific inhalation challenge with wheat flour extracts. Results: The prevalence of sensitization to wheat flour and baker's asthma was 21.0% (25.9% DE, 13.3% IE) and 3.2% (5.1 % DE, 1.8% IE), respectively. DE had an increased risk of sensitization to wheat flour (OR 2.15, 95% CI = 1.03∼4.51). Sensitization to wheat flour and the prevalence of baker's asthma correlated significantly (PR 38.63, 95% CI = 6.14∼243.22). Conclusions: These findings indicate a considerable prevalence of baker's asthma among flour-exposed workers in Korea. Future studies will be required to survey the situation in flour mill companies and seek ways to protect the health and socioeconomic position of flour industry workers.

mtDNA l1778위치의 돌연변이를 가진 Leber씨 유전성 시신경병증과 Leber's plus: 임상적 양상과 유전학적 연구

권순억,황정민,박혜원,강동화,구자성,이광우,노재규 대한신경과학회 1997 대한신경과학회지 Vol.15 No.2

금 카벤 착체합성 및 특성에 관한 연구

정민철,정혜성,김성민,이정훈,박권필,안호근 한국공업화학회 2005 응용화학 Vol.9 No.1

We have been used for the Pt catalyst of cathode electrode in fuel cell. Weak point of Pt electrode are easily deactivated by the CO poisoning which are producing in reaction at electrode. Recent, researchers have developed cathode electrode to avoid the CO poisoning in electrode using the Pt-alloy or another novel metal. We now report Au-carbene complexes as an Au-electrode precursor derived from the reaction of the carbene with the ClAu(PPh₃) complex in THF/MeOH.

Putrescine처리가 절화 카네이션 'Desio'의 화판 노화에 미치는 영향 : Ethylene 발생, ACC synthase, EFE 활성변화 Change of ethylene production and ACC synthase and EFE activities

이인국,권혜정,손기철 建國大學校 附設 農業資源開發硏究所 1993 農資源開發論集 Vol.18 No.-

절화 카네이션 'Desio' 품종의 화판 노화시 발생되는 에칠렌의 발생량은 계절에 따라 달라 2월경 채화된 것은 약 70nl/g·FW/hr를 나타내었으나, 7월에 채화된 것은 4.3nl/g·FW/hr 불과했다. 폴리아민 중 put의 10mM 처리는 EFE의 활성과 에칠렌의 발생을 억제시키고 화판의 노화를 지연시켰으나, 대조구나 put 1Mm의 처리구에 비해 높은 ACC synthase의 활성을 나타내었다. 한편, 1mM put 처리는 ACC synthase의 활성이 억제됨에도 불구하고 에칠렌이 생성되어졌다. 이러한 사실은 기작이 명확치 않으나 put처리가 에칠렌 생합성 과정중 EFE보다 ACC synthase의 활성에 직접적인 영향을 미치는 것을 나타내며, 내생 폴리아민의 농도에 따라 외생 폴리아민의 카네이션 화판의 노화에 미치는 영향이 다름을 나타낸다. Ethylene evolution on the senescence of petals of cut carnation cv. Desio was varied according to the cultural seasons, where 70 ul/g·fw/hr of ethylene was produced in Feb. harvest, but only 4.3 ul/g·fw/hr in July. Despite that 10mM putrescine treatment on the petals inhibited ethylene production and EFE activity, and delayed the senescence, it rapidly stimulated ACC synthase activity over those of control and 1mM putrescine treatment. In addition, ethylene was produced in the 1mM putrescine treatment even though ACC synthase acitiviy was inhibited. This fact indicates that purtrescine has influence on rather EFE than ACC synthase on the biosynthesis of ethylene and the effect of exogenous polyamines on the senescence is varied according to the level of endogenous polamines in the petals of cut carnation.

삼일열 말라리아에 합병된 비장 파열 1예

홍경욱,이정아,김원진,박철민,권혜리,박혜원,엄중식 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

국내의 토착형 말라리아는 삼일열 말라리아로, 1993년부터 재유행이 시작되었다. 말라리아의 중요한 합병증으로 드물지만 비장 파열이 있는데, 이는 주로 삼일열 말라리아에 의해서 발생되며, 국내에서는 1999년 말라리아에 의한 비장 파열로 비장 절제술을 시행한 예가 보고된 바 있다. 현재까지는 비장 파열이 있을 때 비장 절제술이 일차적인 치료로 되어 있으나, 비장 절제술 후의 감염 위험성이 크므로, 활력 징후가 불안정하거나, 출혈이 지속되는 소견이 보이지 않으면 가급적 보존적 치료를 하는 것이 추천된다. 저자들은 비장 파열이 동반된 말라리아 환자에서 비장 절제술을 시행하지 않고 보존적 치료로 호전된 예를 경험하여 보고하는 바이다. Plasmodium vivax has been the predominant Plasmodium species in the Republic of Korea and reemerged in 1993. Spontaneous rupture of malarial spleen is a rare but important complication associated with P. vivax infection. Only one case of spontaneous rupture of malarial spleen was reported in Korea in 1999. Splenectomy is still accepted as the treatment of choice in cases of spontaneous rupture of the spleen. But, considering increased risk of postsplenectomy infecion, splenectomy should be reserved for those patients with severe rupture or those with continued or recurrent bleeding. And conservative treatment should be considered in selected, closely monitored patients. We report a patient with P. vivax malaria who developed a spontaneous splenic rupture and was improved by conservative treatment.

CT-26 선암을 접종한 마우스에서 Iodine-131-Iodomisonidazole 의 생체분포 및 종양저산소증의 영상화

Yang, David J,Kim, E Edmund,김혜원,김창근,윤권하,김현정,정선관,노병석,Lee, Hyun-Chul 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.3

urpose: Misonidazole is a radiosensitizer that binds in hypoxic cells. The purpose of this study was to find out the feasibility of I-131-Iodomisonidazole (IMISO) for imaging of tumor hypoxia. Materials and Methods: Tosyl precursor was dissolved in acetonitrile and I-131-NaI was added to synthesize IMISO. Balb/c mice inoculated with CT-26 adenocarcinoma were injected with IMISO. Mice were sacrificed at 1,2,4,24 hr and % of injected dose per gram of tissue (%ID/g) was determined. For scintigraphy and MRI, mouse bearing CT-26 adenocarcinoma was administered with IMISO and imaging was performed 4 hr after. Then, mouse body was fixed and microtomized slice was placed on radiographic film for autoradiography. Results: %ID/g of tumor was 1.64 (1h), 0.98 (2h), 0.85 (4h) and 0.20 (24h), respectively. At 24h, %ID/g of tumor was higher than that of all other tissues except thyroid. Tumor to muscle ratio increased with time and tumor to blood ratio also increased with time and reached 1.53 at 24 hr. On autoradiogram, tumor was well visualized as an increased activity in central hypoxic area of the tumor which corresponds to the area of high signal intensity on T2-weighted MR image. On scintigraphy, tumor uptake was visualized. Conclusion: This results suggest that IMISO may have a potential for tumor hypoxia imaging in mouse model. However, further study is needed to improve it's localization in tumor tissue and to achieve acceptable images of tumor hypoxia.