초기성인의 생활습관과 당뇨에 대한 지식

소선이,마지은,고지윤,김은혜,박현화,서유진,서형은,유은미,이하늬,이혜인,정지연,현혜리,이자형,정덕유,강지숙 이화여자대학교 간호과학대학 2009 이화간호학회지 Vol.- No.43

Purposes :The purposes of this study was to investigate the self-managing status according to the life styles and the diabetic knowledge of early adulthood. The subjects in this study were 240people, the early adult aged twenties to thirties living in the metropolitan area. Data were collected by using self-administered questionnaires that measure about the knowledge of diabetes; the dietetic behavior; the knowledge of diet; the exercise behavior; the knowledge of exercise. Descriptive statistics, t-test, ANOVA, and correlation were used for data analysis. Result :1. At the knowledge of diabetes degree based on the general character, the subjects who had experiences of diabetic education have higher degree of the diabetic knowledge. 2. At the knowledge of diabetes degree according to the life style, the subjects who have regular diet are appeared highly. Also the subjects who don't take much food of animal origin have higher degree. 3. At the knowledge of diet based on the life style, the subjects who don't keep three times meals a day are appeared highly. Also the subjects who have regular diet have higher degree. 4. At the knowledge of exercise according to the life style, the subjects who take extra nutritions 3-4 times a week are appeared highly. Although the subjects tend to know about dietary, exercise and health management, it showed that they actually don't perform what they know in their everyday of life. The reason for this could be the lack of perceived seriousness about diabetes mellitus. Thus as nursing professionals, we should provide them proper health education and support. Moreover, advanced research on the empowerment is warranted.

Gold-coated silicon nanowire-graphene core-shell composite film as a polymer binder-free anode for rechargeable lithium-ion batteries

Kim, H.J.,Lee, S.E.,Lee, J.,Jung, J.Y.,Lee, E.S.,Choi, J.H.,Jung, J.H.,Oh, M.,Hyun, S.,Choi, D.G. North-Holland 2014 Physica E, Low-dimensional systems & nanostructure Vol.61 No.-

<P>We designed and fabricated a gold (Au)-coated nanowires/graphene (Au-SiNWs/G) hybrid composite as a polymer binder free anode for rechargeable lithium ion batteries (LIBs). A large amount of SiNWs for LIB anode materials can be prepared by metal assisted chemical etching (MaCE) process. The Au-SiNVVs/G composite film on current collector was obtained by vacuum filtration using an anodic aluminum oxide (AAO) membrane and hot pressing method. Our experimental results show that the Au-SiNVVs/G composite has a stable reversible capacity of about 1520 mA h/g which was maintained for 20 cycles. The Au-SiNWs/G composite anode showed much better cycling performance than SiNWs/ polyvinylidene fluoride (PVDE)/Super-P, SiNWs/G composite, and pure SiNWs anodes. The improved electrochemical properties of the Au-SiNWs/G composite anode material is mainly ascribed to the composite's porous network structure.,(C) 2014 Elsevier B.V. All rights reserved.</P>

피부감작성에 있어 Local lymph node의 반응성 연구

이종권,박재현,김형수,정승태,엄준호,황인창,장은정,윤소미,남기택,허용,오혜영 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

알레르기설 접촉 괴부염은 다양한 화학물질에 의해 유포될 수 있다. 화학물질이 피부 감작성을 알 킬 수 있는지 여부는 전통적으로 기니픽을 사용한 등물모겔이 이용되어 쏜으나, 최근에는 마우스를 이용한 local Iymph node assily tLLNA) 발법 개발이 요구되고 있떠 본 연구는 focal Iymph not assa)·의 시험방법을 개발하고, 감작을 일으키는 기전을 파악하고자 하였다. 콕헝물질로는 패표적 접촉 알러전인 DffCB(2,4-dinitrochlorobenzone), 호홉 알러젠인 fDl(toluene diisocyanate), 약한 알러젠인Cf.(o-kerplcinamaldehl,do:4, 강한 자극물질인 SLS(sodum lauryl sulfate)를 사용하였다. 각 시험물질 2sr4를 적절한 농도로 6-8주령의 암컷 Balb/c 마우스의 귀의 배측에 3일간 도포한 후 5일째에 부검하여 이개림프절, 귀의 변화 등을 관찰하였다. DNCB, TDI를 도포한 마우스의 이개 림프절의 중량은 대조군에 비해 증가하였으며, 고농도의 HCA를 투여한 마우스에서의 림프절 중량도 증가하였다. SLS를 투여한 군의 림프걸치 중량은 저농도에서는 변화가 없었으나, 고농도에서는 중량이 증가하였다. 꼬리정맥에 3H-thymidine을 투여하여 림프절의 증식정도를 파악한 결과, BNCB를 도포한 군에서는 프절의 증식지수(Stimulation 1.Idex, Sl)가 용량별로 20.3, 24.6, 27.5로 관찰되었으며, TDI군에서는 각 19.0, 29.T, 42.3으로 관찰되첬고 HCA군에서는 각각 3.8, 9.7, 19.8로 관찰되었다. sLs군에서는 0.8 3.7, 6.6으로 관찰되었다. 이잖끈 결과 fH-thynudine을 이용한 피부 감작성 평가는 기니픽을 대체할수 있는 방법으로 _평가되었다. 그러나 방사선이용이라는 단점과 강한 자극성물질에서의 위양성 반응이 관찰되어 BrdU(Eromodeoklpuddine) 면역조직차학기법으로 시험한 결과 비방사선법도 이용 가능함을 알 수 있었다. 또는 TDI를 처리한 마우스의 림프절에서 cytoklne의 발현을 RT-PCR로 측정한 결과 IL-2 IL-4, U-10과 INf-r의 mRNA발현이 증가하였으며, HCA를 처리한 경우에는 토-4, IL-10. INf-γ mRNA의 발현이 증가 하였다. 또한 B리CB의 경우에는 U-4의 발현이 증가하였다. 그러나, sLs의 경우에는 IL-?, IL-4, 0--10 과 rNF-r꼭 발현이 증가되지 않았다. 이러한 결과는 LLNA를 이용한 c번okine의 n)교NA발현이 유용싼 측정 지포중 하나가 될 수 있을 것으로 생각되며. 특히 IL-4의 발현정도의 증가는 알레르기 유발성을 평가할 유용한 생체지표의 하나가 될 수 있을 것으로 생각되어진다. Allergic contact dermatitis (skin sensitization) may be caused by a wide variety of chemicals. A murine local lymph node assay(LLNA) has been developed as an alternative to guinea pig models for assessing the contact sensitization potential of chemical. First, the objective of this study was to evaluate allergenecity of chemicals by LLNA. Secondly, we aimed to investigate the possibility of development of non-radio isotopic endpoint for LLNA using immunohistochemistry. Thirdly, we aimed to analyze cytokine mRNA expression of draining lymph node cell in mice exposed to chemical allergen and irritant. In this study, contact allergen, dinitrochlorobenzone (DNCB), respiratory allergen toluene diisocyanate (TDI) and moderate allergen, α-hexylcinnamaldehyde (HCA) were used as positive chemicals and the irritant, sodium lauryl sulfate(SLS) also used as reference chemical. The stimulation index (SI) of lymph node cell in the mice treated with allergens. DNCB, TDI, and HCA were more increased dose-dependently compared to vehicle control by ^(3)H-thymidine uptake. And SI of lymph node cell in strong irritant, SLS were also increased dose-dependently compared to control. The BrdU(Bromodeoxyuridine) LI of lymph node in DNCB and TDI were dramatically increased campared to that of control. However, the LI of lymph node in SLS were not significantly increased compared to vehicle control. This data represents that BrdU LI of lymph node could be one of useful method for screening for irritant and allergen. The expression of IL-2, IL-4, IL-10 and IFN-γ mRNA was increased in draining auricular lymph node cell of the mice treated with TDI by RT-PCR. The level of IL-4, IL-10 and IFN-γmRNA was increased in mice treated with HCA. The expression of IL-4 was increased in lymph node cell of mice treated with DNCB. However, the level of IL-2, IL-4, IL-10 and IFN-γ in lymph node cell of mice treated with SLS was not increased. These results suggest the measurement for increase in level of IL-4 mRNA expression could by one of the method for screening the allergenic potential.

Design of the RAON Accelerator Systems

전동오,I. S. Hong,H. J. Kim,J. W. Kim,R. M. Bodenstein,차혁진,S. J. Choi,최숙,O. R. Choi,H. Do,B. H. Choi,C. J. Choi,J. Han,W. K. Han,M. O. Hyun,H. Jang,J. D. Joo,M. J. Joung,H. C. Jung,Y. C. Jung,김도균,E. Kim 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.7

The RAON is the name of the heavy ion accelerator facility under construction in Korea thatincludes the In-flight Fragment (IF) and Isotope Separation On-Line (ISOL) facilities to supportcutting-edge research in various science fields. The superconducting linac is the driver for the IFfacility that can accelerate beams from proton to uranium with 200 MeV/u, 400 kW (for uraniumbeam). A 70-MeV, 1-mA H− cyclotron is the driver for the ISOL facility and is followed by apost-accelerator consisting of s superconducting linac that can accelerate rare-isotope (RI) beamsand deliver them to experimental halls. These facilities provide high-intensity stable ion and rareisotope (RI) beams for domestic and international users. In this paper, design and prototypingefforts for the RAON accelerator systems are presented.

Oxidative Stress Increases Phosphorylation of IκB Kinase-α by Enhancing NF-κB-Inducing Kinase after Transient Focal Cerebral Ischemia

Song, Yun Seon,Kim, Min-Soo,Kim, Hyun-Ae,Jung, Bo-In,Yang, Jiwon,Narasimhan, Purnima,Kim, Gab Seok,Jung, Joo Eun,Park, Eun-Hee,Chan, Pak H SAGE Publications 2010 Journal of cerebral blood flow and metabolism Vol.30 No.7

<P> The IκB kinase (IKK) complex is a central component in the classic activation of the nuclear factor-κB (NF-κB) pathway. It has been reported to function in physiologic responses, including cell death and inflammation. We have shown that IKK is regulated by oxidative status after transient focal cerebral ischemia (tFCI) in mice. However, the mechanism by which oxidative stress influences IKKs after tFCI is largely unknown. Nuclear accumulation and phosphorylation of IKKα (pIKKα) were observed 1 h after 30 mins of tFCI in mice. In copper/zinc-superoxide dismutase knockout mice, levels of NF-κB-inducing kinase (NIK) (an upstream kinase of IKKα), pIKKα, and phosphorylation of histone H3 (pH3) on Ser10 were increased after tFCI and were higher than in wild-type mice. Immunohistochemistry showed nuclear accumulation and pIKKα in mouse brain endothelial cells after tFCI. Nuclear factor-κB-inducing kinase was increased, and it enhanced pH3 by inducing pIKKα after oxygen-glucose deprivation (OGD) in mouse brain endothelial cells. Both NIK and pH3 interactions with IKKα were confirmed by coimmunoprecipitation. Treatment with IKKα small interfering RNA significantly reduced cell death after OGD. These results suggest that augmentation of NIK, IKKα, and pH3 in response to oxidative stress is involved in cell death after cerebral ischemia (or stroke). </P>

한반도 바람지도 구축에 관한 연구 : I. 원격탐사자료를 이용한 해상풍력자원 평가 I. Evaluation of Offshore Wind Resources Using Remote-Sensing Data

김현구,이화운,정우식 한국대기환경학회 2005 한국대기환경학회지 Vol.21 No.1

In order to understand regional wind characteristics and to estimate offshore wind resources, a wind map of the Korean Peninsula was established using remote-sensing data from the satellite, U.S. NASA QuikSCAT which has been deployed for the SeaWinds Project since 1999. According to the linear regression result between the wind map data and in-situ marine-buoy data, the correlation factor was greatly improved up to 0.87 by blending the remote-sensing data of QuikSCAT with U.S. NCEP/NCAR CDAS reanalysis data to eliminate precipitation interference and to increase temporal resolution. It is found from the established wind map that the wind speed in winter is prominent temporally and the South Sea shows spatially high energy density over the wind class 6. The reason is deduced that the north-west winds through the Yellow Sea and the north-east winds through the East Sea derived by the low pressure developed in Japan are accelerated passing through the Korea Channel and formed high wind energy region in the South Sea; the same trends are confirmed from the statistical analysis of the meteorological observation data of KMA.

풍력발전 단지조성을 위한 바람환경 분석

김현구,최재우,손정봉,정우식,이화운 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.6

An analysis of wind environments using computational fluid dynamics and an evaluation of wind resources using measurement data obtained from meteorological observation sites at Homi-Cape, Pohang have been carrid out for siting a wind farm. It was shown that a numerical simulation using computational fluid dynamics would provide reliable wind resource map in complex terrain with land-sea breeze condition. As a result of this investigation, Homi-Cape wind farm with 11.25 MW capacity has been designed for maximum power generation and 25.7GWh electricity production is predicted.

스케일이 있는 급수관내의 유도초음파의 전파 특성에 관한 연구

송성진,김영환,이동훈,이현동,배철호,박정훈 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.1

배관 내의 스케일은 통수비를 감소시키므로 배관을 적절히 관리하기 위해서는 스케일량에 대한 정량적인 평가가 필수적이다. 상수도 급수관내의 스케일량을 평가하기 위해서 유도초음파를 사용하였다. 가변각 웻지를 사용하여 유도 초음파의 여러 모드를 발생시키고, 노후 배관을 따라서 전파하는 특성을 분석하였다. 실험적으로 관내의 스케일이 증가함에 따라서 f×d=1.5㎒·㎜인 경우에 F(M,2) 모드들의 진폭이 크게 감소하는 것을 알 수 있었다. 본 연구의 결과로 상수도 급수관의 스케일량 평가에 적합한 유도 초음파는 F(M,2) 모드들임을 알 수 있었다. Since the scale in pipes reduces the flow rate, a quantitative evaluation of the scale is essential for the proper maintenance of pipes. Guided waves were employed to estimate the amount of scale in water supplying pipes. Using variable angle wedge, several modes of guided waves were generated and their propagation charcteristics along the pipes with scale were analyzed. It was experimentally observed that the amplitude of F(M,2) modes at f×d=1.5㎒·㎜ decreased significantly with increasing amount of scale. The present study showed that F(M,2) modes were optimal to evaluate the scale in water supplying pipes.

기술제품의 기능적·감성적 요인들이 지속적 사용가능성에 미치는 영향에 관한 연구

김지영,이현정,배재현 梨花女子大學校 社會科學大學 社會科學硏究所 2011 사회과학연구논총 Vol.25 No.-

기술제품은 짧은 제품수명주기로 인해 기업의 지속적인 수익원이 되고 있다. 이에 기업들은 기술제품의 기능적인 요소뿐만 아니라 감성적인 요소를 통해 사용자들에게 더 가까이 다가가려고 노력하고 있다. 이러한 관점에서 최근 마케팅과 관련된 분야에서는 사용자와 기술제품의 관계를 밝히려는 다양한 연구가 이루어지고 있다. 따라서 본 연구에서는 지각된 사용용이성, 지각된 유용성, 지각된 즐거움, 지각된 매력성, 사용자 만족, 지속적 사용가능성에 대한 문헌연구를 통하여 기술제품의 기능적·감성적 요인이 사용자 만족과 전환비용의 매개적 역할을 중심으로 지속적 사용가능성에 미치는 영향에 관한 연구를 실시하였다. 연구 결과 기술제품 사용에 있어 기능적 요인 뿐 아니라 감성적 요인도 매우 중요하다는 점을 제시 하였으며 기술제품에 만족을 했을 때 전환비용이 높게 지각되어 지속적 사용의도가 높아짐을 시사한다. As the technological products become crucial for corporate’s constant profit there is an increasing amount of research on relationship between users and technological product. This study extends the existing studies which considered only functional factors as the determinants for user satisfaction. We propose the influence of emotional factor in technology acceptance. Based on the survey data from Korean consumers, perceived enjoyment and attractiveness affect user satisfaction as well as functional factors. Further, switching costs mediates between user satisfaction and patronage.

The rate of gastric MALT lymphoma regression with H. pylori eradication alone in Korea; single center study (초)

( Yoon J. Choi ),( Dong H. Lee ),( Young S. Park ),( Na Young Kim ),( Hyun C. Jung ),( In S. Song ) 대한내과학회 2010 대한내과학회 추계학술대회 Vol.2010 No.-