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      • K 大學 病院 患者의 病院 選擇 動機 分析

        南銀祐,朴昌式,安熙都,徐判洙 高神大學校 保健科學硏究所 1991 보건과학연구소보 Vol.1 No.-

        The subject hospital is a Christian health care institution which is a 720 beds university hospitals and has been providing health care services and outpatient services located in Pusan, since its foundation in 1950. The purpose of this study is to develop marketing strategy for this University Hospital by identifying factors associated with the patients' attitudes toward their choice and images, with following objectives: 1) to identify patient choice factors 2) to analyze patients' images toward the hospital 3) to compare above informations with other hospitals in Pusan, and 4) to analyze population served with demographic and economic variables. The survey data retrieved from the samples of 140 outpatients and 100 intelligents were analyzed by Chi-square and Mann Whitney U test with the confidence level at less than 0.05. Major findings from the study were as follows: 1) Hospital choice motivation factors a. fovorable factors toward the choice of hospital revealed: (1) good facilities and equipments (50.2%) (2) large hospital (38.4%) (3) recommended by neighbor (35.0%) 2) Hospital image factors a. favorable factors: (1) modern equipments and technology sufficiency (2) friendliness of office employees (3) kindness of doctors b. unfavorable factors: (1) high cost of care (2) long waiting time for clinic examinations and prescription filling (3) traffic inconveniency 3) Comparisons with other hospitals showed disadvantages in the areas of: (1) inpatients are more favorable than outpatients toward good facilities and equipments, friendly doctors and nursing personnel, compared to the (2) unfavorable attitudes toward the long waiting time and impolite nurses, cleanliness, parking space shortage, etc. In reviewing the marketing information analysis, the hospital should carefully review the result, and endeavor toward the improvement of hospital services as well as image building, in regard to those areas showing negative results, in the marketing and strategic planning efforts with unified supports from the entire staffs and employees of the hospital.

      • KCI등재

        Comprehensive genomic analyses with 115 plastomes from algae to seed plants: structure, gene contents, GC contents, and introns

        Eun‑Chae Kwon,Jong‑Hwa Kim,NamSoo Kim 한국유전학회 2020 Genes & Genomics Vol.42 No.5

        Background Chloroplasts are a common character in plants. The chloroplasts in each plant lineage have shaped their own genomes, plastomes, by structural changes and transferring many genes to nuclear genomes during plant evolution. Some plastid genes have introns that are mostly group II introns. Objective This study aimed to get genomic and evolutionary insights on the plastomes from green algae to flowering plants. Methods Plastomes of 115 species from green algae, bryophytes, pteridophytes (spore bearing vascular plants), gymnosperms, and angiosperms were mined from NCBI organelle genome database. Plastome structure, gene contents and GC contents were analyzed by the in-house developed Phyton code. Intronic features including presence/absence, length, intron phases were analyzed by manually in the annotated information in NCBI. Results The canonical quadripartite structures were retained in most plastomes except of a few plastomes that had lost an invert repeat (IR). Expansion or reduction or deletion of IRs resulted in the length variation of the plastomes. The number of protein coding genes ranged from 40 to 92 with an average 79.43 ± 5.84 per plastome and gene losses were apparent in specific lineages. The number of trn genes ranged from 13 to 33 with an average 21.19 ± 2.42 per plastome. Ribosomal RNA genes, rrn, were located in the IRs so that they were present in a duplicate except of the species that had lost one of the IR. GC contents were variable from 24.9 to 51.0% with an average 38.21 ± 3.27%, indicating bias to high AT contents. Plastid introns were present in 18 protein coding genes, six trn genes, and one rrn gene. Intron losses occurred among the orthologous genes in different plant lineages. The plastid introns were long compared with the nuclear introns, which might be related with the spliceosome nuclear introns and self-splicing group II plastid introns. The trnK-UUU intron contained the maturase encoding matK gene except in the chlorophyte algae and monilophyte ferns in which the trnK-UUU was lost, but matK retained. There were many annotation artefacts in the intron positions in the NCBI database. In the analysis of intron phases, phase 0 introns were more frequent than those of phase 2 and 3 introns. Phase polymorphism was observed in the introns of clpP which was derived from nucleotide insertion. Plastid trn introns were long compared to the archaeal or eukaryotic nuclear tRNA introns. Of the six plastid trn introns, one was at the D loop and other five were at the anticodon loop. The insertion sites were conserved among the trn genes in archaea, eukaryotic nuclear and plastid tRNA genes. Conclusions Current study refurbrished the previous findings of structural variations, gene contents, and GC contents of the chloroplast genomes from green algae to flowering plants. The study also included some noble findings and discussions on the plastome introns including their length variations and phase variation. We also presented and corrected some false annotations on the introns in protein coding and tRNA genes in the genome database, which might be confirmed by the chloroplast transcriptome analysis in the future.

      • KCI등재후보

        이부성형술에서 강선 고정술과 소강판 고정술간의 안정성에 관한 임상적 연구

        이은택,김수남,민승기,이동근,송종민 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.3

        Performing genioplasty for greater stability of the changed chin position, incision, dissection, osteotomy design and fixation are important technical considerations. Basically, wire osteosynthesis method has been used in genioplasty, but plate/screw osteosynthesis has been introduced in rigid fixation. The purpose of this study is that comparison of stability between wire and plate/screw osteosynthesis in genioplasty. In this study, the genioplasty groups were divided into three groups ; advanced genioplasty group, reduction genioplasty group, advanced with reduction genioplasty group. In wire osteosynthesis groups, there were 15patients who had advanced genioplasty, 13patients who had reduction genioplasty, and 12patients who had advanced with reduction genioplasty. In plate/screw osteosynthesis groups, there were 15patients who had advanced genioplasty, 13patients who had reduction genioplasty, and 13patients who had advnaced with reduction genioplasty. Lateral cephalograms ; pre- and postoperatively, postoperatively 1months, and at the latest follow-up(>6months); were analyzed by linear measurement to evaluate changes in position(hard tissue B, Pogonion point) and compare relapse between both groups.

      • CA 125치가 증가된 난소종괴 환자에서 악성 감별을 위한 CA 15-3과 TAG 72의 효용성

        이수미,김영탁,정동근,남주현,목정은 울산대학교 의과대학 1992 울산의대학술지 Vol.1 No.1

        The purpose of our study was to evaluate whether the combined use of serum tumor markers, CA 15-3 and TAG 72 could improve the efficacy for discriminating malignant from benign ovarian masses in patients with elevated serum CA 125 levels. Serum CA 15-3 and TAG 72 were preoperatively measured by immunoradiometric assay in 78 patients with pelvic masses who had elevated serum CA 125 levels above 35 U/ml. In 32 patients with epithelial ovarian cancers, serum CA 125 levels were elevated above 65 U/ml in 97% and serum CA 15-3(>30U/ml) and TAG 72(>10 u/ml) levels were elevated in 59% and 50%, respectively, suggesting relatively low sensitivity of CA 15-3 and TAG 72. However, in 41 patients with benign ovarian tumors, elevations of these two markers were detected only in 7% and 5%, respectively, and particularly, both markers were not elevated among all the aptients over 50 years of age. Coordinate elevations of CA 125(>35U/ml) and CA 15-3(>30U/ml) or TAG 72(>10 U/ml) could discriminate epithelial ovarian cancers from benign masses with a sensitivity of 72% and specificity of 90%. Among patients over 50 years of age, sensitivity and specificity were increased to 79% and 100%, respectively. It is concluded that the combined use of CA 15-3 and TAG 72 with CA 125 could obtain an improved efficacy for discrimination of epithelial ovarian cancer, especially among patients over 50 years of age.

      • KCI등재

        PILOMATRICOMA 치험 1례

        김은철,이창우,임창준,이동근,김수남,양희창 大韓顎顔面成形再建外科學會 1990 Maxillofacial Plastic Reconstructive Surgery Vol.12 No.3

        The pilomatricoma (calcifying epithelioma of Malherbe) is rare benign hard, spherical and freely movable cutaneous tumor, which was differentiated from hair cells, particulary hair cortex cells. It is usually occured as a single, asymptomatic, 0.5 cm to 3.0 cm sized, deep seated, firm nodule, covered by normal or pink skin. It arises chiefly in young people, including children, and most often in the head, neck and upper extrimites. The authers experienced a case of pilomatricoma which occured in preauricular region. This case was summarized as follows. 1. 10 years old female has suffered from hard subepidermal mass on preauricular area and she visited our out patient clinic. So we performed surgical extirpation and the excised specimen was pathologically examined. 2. Grossly the tumor measures 2.0 cm in diameter and firm, bosselated, spherical shaped which covered by a thin layer of fibrous tissue. On cut section, it shows spicular gritty surfaces, well encapsulation, interwoven and keratotic lamellae. 3. Histopathologically, the epithelial masses of the tumor are composed of two type of cells, basophilic cells and shodow cells. The basophilic cells resemble hair matrix cells which posses round or elogated, deeply basophilic nuclei and scanty cytoplasm.The shadow cells show a central, unstained shadow at the site of the lost nucleus. Gradual development of basophilic cells into shadow cells can be observed. Foci of calcification are present within the lobule of shadow cells. The stroma of the tumor shows a considerable foreign body giant cell reaction adjacent to the shadow cells. 4. No recurrence was observed until post - operative 40 months.

      • 위장관 출혈을 일으킨 공장의 형활근종 1예

        김병수,장성종,부귀범,조운택,박찬국,김만우,변주남,김정용,전호종 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.1

        Small bowel leiomyoma is a rare tumor which may occur wherever smooth muscle is present. The small bowel is the most common site and it makes up 20~30% of all benign small intestinal neoplasms. A spectrum of symptoms are common ranging from nausea, vomiting, abdominal pain, to massive intestinal bleeding. Bleeding is the most common symptom and is usually gross and recurrent. Occasionally it may be life threatening. But, the most serious problem is both the absence of specific clinical symptoms, and the difficulties shown in radiological diagnostics of the small bowel. If conventional diagnostic methods fail to reveal any positive findings for gastrointestinal bleeding, the diagnosis of intestinal leiomyoma should be suspected and an SMA angiography shoud be performed. The angiographic criteria of small bowel leiomyoma is very characteristic. We present a case of leiomyoma with considerable and prolonged gastrointestinal bleeding, which was diagnosed by angiography. A 61-year old woman was admitted with a history of melena over the last 10 days. An SMA angiography showed a hypervascular mass with a diameter of 3×3cm. A segmental resection was performed under the impression of the gastrointestinal bleeding due to leiomyoma of the small bowel. Microscopic examination of the lesion shows interlacing or whorl bundles of spindle shaped ces and no mitosis.

      • KCI등재
      • 로드셀을 이용한 직물의 신축성 측정에 관한 연구

        최정수,김은석,주기세,왕지남 한국경영과학회 2002 한국경영과학회 학술대회논문집 Vol.- No.1(1)

        So far, the common elasticity data of textile fabrics has not been present because the method depends on the knowledge of measurement operators. In this paper, the new measurement equipment using road cell is presented to measure the coefficient of textile fabrics in real time. The measurement method is based on the volt: among textile fabrics. The textiles with strong elasticity are high voltage produced from others are low. The presented method can be applied to visualize the textile, sew the cloth, contrc textile fabrics. Also, these measurement datum are used to B2B electronic trading system.

      • KCI등재

        主要 眺望點에서 바라본 港灣景觀의 注視特性에 관한 硏究

        김은일,정성구,윤진보,신남수 대한건축학회 2004 대한건축학회논문집 Vol.20 No.7

        It is necessary to research for environmental features of regions rather than each building and scenery to form desirable city landscape that describes placeness concretely. In case of Korea, vast harbors and industry complex are generally located in the waterfront of port cities because the waterfront is noticed as one factor which supplies a fresh ground. So, waterfront forms a wide and long blackout curtain that causes the destruction of nature, shapes a factory structure curtain, and completely covers hinterland landscape. It makes hard for citizens to access to the seaside, depriving capacity of waterfront for water-familiar, and destructing beautiful seashore environment. This research project is to provide those architects or planners with the design guidelines of improving port and hinterland landscape. To do so, this study is carried out the physiological evaluation making eye fixation behaviors. The main results were summarized as follows: 1) Satisfaction with the ports' scenery turned out being given high estimation according as the objections being seen is more natural, a scale of ports' landscape elements is larger, and shape of landscape elements are simpler. 2) Distribution of a visual point is concentrated on facilities that have unique shapes and is under the influence of seashore line, letters carved in buildings and conspicuous colors. In addition, it tends to gather a visual point that facility's movement would be expected. 3) Eye fixation behaviors stops at unique shapes, structural lines of the physical elements and color factors of the objects. And it was judged that human recognized the object through this. 4) Scenery that include large natural element has a flexible movement of view and make general populace see the object for more long time. Therefore, it is necessary to examine the vista point on view-distance with research on improving port's naturality.

      • High Pressure Liquid Chromatography를 이용한 인진호의 유효성분 확인

        박남선,박성옥,안영은,이진희,장수자,정은진,지경단 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

        In present day, components of Artemisiae Carpillaris Herba(A.C.H) was investigated by HPLC method. On condition of ODS-10column, 25% acetonitrile for mobile phase, 254nm of UV Detector, the extracts of A.C.H was analyzed. As the result, peaks of coumarin derivatives, at retention time 2.16 and 2.18, were found.

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