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      • 축구 활동이 비만 초등학생의 혈중 지질에 미치는 영향

        전태원,박익렬,엄우섭,이동기,우재홍,김경래,김은경,서한교,전병환,김광준,정진욱,박성태 서울대학교 체육연구소 2002 서울大學校 體育硏究所論集 Vol.23 No.2

        The purpose of this study is to investigate the effect of Soccer playing in Plasma Lipids in Elementary Obesity Student. Subject for this study were consisted of 16 male(exercise group : 8, non-exercise group : 8), who were over 25% of body fat. Exercise group played soccer 3 times per week, one time was 90 minutes. Weight, % body fat, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglyceride, c-ratio were measured at three time periods before exercise begin, and 5 and 8 weeks. The results were summarized as follow: Exercise group decreased significantly more than non-exercise group about weight, % body fat, total cholesterol, low density lipoprotein cholesterol, triglyceride, c-ratio. And Exercise group increased significantly more than non-exercise group about high density lipoprotein cholesterol. In conclusion, the regular aerobic exercise(soccer playing) for 10 weeks has great effects on control of serum lipid which is related to the increase well-being(reduced coronary heart disease, hyperlipidemia, hypertension, obesity et all.) in elementary obesity male student.

      • 통풍 환자에서의 지질대사

        이은우,강기서,강수용,이한준,김경환,임정일,박철경 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.2

        Objective: To evaluate hyperlipidemia, a msjor tisk factor of coronary artery disease, frequently asscoiated with gout patients, we compared the mean lipid level of gout patient with that of non-gout male and accessed statistical significance for treatment of gout patient. Method: This study ws performed in the 266 male gout outpatients of the CAU medical center, who had serum lipid level test from Apr. 1996 to Aug. 2000. Serum uric acid, total cholesterol, triglyceride, HDL -cholesterol, and LDL-cholesterol level were measured after 12 hours of fasting. The patients with high lipid level were further evaluated into each type of the hyperlipidemia through electrophoresis study, and the test results were compared with that of the non-gout male adults(40∼60yr), and the statistical significance was examined. Results : The gout patients showed high levels of total cholesterol, triglyceride, and LDL-cholesterol. Especially they showed high level of triglyceride and LDL-cholesterol which suggested as the risk factors of atherosclerosis and coronary heart disease, but shoewed low level of HDL -cholesterol. But there were no definite relations between lipid level and other factors auch as age of patient, initial uric acid ;eve; and duration od gout. Conclusion: To evaluate the risk factors of atherosclerotic change of cadriac vascular system in gout patient, screening tests of serum lipid level of the patient seem mandatory.

      • KCI등재

        백서의 치아이동 시 피질골 천공이 치주조직의 OPG, RANK, RANKL의 발현에 미치는 영향

        박우경,김성식,박수병,손우성,김용덕,전은숙,박미화 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.3

        치아이동 시 피질골 천공이 치조골 재형성에 미치는 영향을 알아보기 위해서 생후 15주된 자성백서를 사용하여 피질골 천공 후 치아이동을 실시한 실험군(Tooth movement with cortical punching: TMC group, n = 16)과 교정적 치아이동만 실시한 대조군(Tooth movement only group: TM group, n = 16)의 치아주위조직을 면역조직화학염색을 통하여 관찰하였다. 실험군과 대조군의 실험동물에 20 gm의 힘으로 상악 전치부 사이를 이개시키는 치아이동을 시행하였으며 실험군에서는 상악 전치부 구개부위에 피질골 천공을 실시하였다. 치아이동 후 1, 4, 7, 14일째에 실험군과 대조군의 실험동물을 희생시켰다. 면역조직화학염색법으로 OPG, RANK, RANKL의 발현을 비교한 결과, OPG의 발현은 양 군 모두에서 미처치 대조군에 비하여 감소되었으나, 실험군에서의 발현이 대조군보다 컸으며, RANK, RANKL은 피질골 천공을 시행한 경우에 더 강한 발현을 보이는 것이 관찰되었다. 따라서 피질골 천공이 치주조직의 OPG, RANK, RANKL의 발현에 영향을 미치며 치조골의 재형성을 향상시키는 것을 알 수 있었다. Objective: The purpose of this study was to investigate whether cortical punching could stimulate the expression of OPG, RANK, and RANKL during tooth movement by immunohistochemistry. Methods: 34 sprague-dawley rats (15 weeks old) were allocated into 3 groups: TMC group (experimental group; Tooth Movement with Corticotomy, n = 16), TM group (control group; Tooth Movement only group, n = 16), and non-treatment group (n = 2). 20 gm of orthodontic force was applied to rat incisors by inserting elastic bands. The duration of force application was 1, 4, 7 and 14 days. A microscrew (diameter 1.2 mm) was used for cortical punching of the palatal side of the upper incisors in the TMC group. Results: Distributions of OPG, RANK, and RANKL were evaluated by immunohistochemistry. OPG, RANK and RANKL were observed on experimental and control groups. On the compression side, the degree of the expression of OPG decreased in both groups. The expression of RANK was most prominent in the experimental group of day 4. The expression of RANKL was most intensive and extensive in the experimental group of day 7. However, the expression of OPG was decreased in the experimental and control groups compared to the non treatment group. The expression of OPG, RANK and RANKL after force application were decreased at day 14. Conclusions: These findings suggested that cortical punching might stimulate remodeling of alveolar bone during a 2 week period of tooth movement without any pathologic change.

      • Ice-On-Coil형 축열조의 해석

        김경훈,전용은 金烏工科大學校 1998 論文集 Vol.19 No.-

        An ice-on-coil storage tank has been modeled to analyze the charging and discharging processes in the ics storage system. This paper describes the basic heat transfer analysis and presents the characteristics of the charging and discharging modes determined from the model. The series conifiguration with the chiller upstream is common in the ice-on-coil systems. Chilled water leaving the chiller passes through a large number of small tubes in the tank that effectively transfer the heat from the storage medium to the transport fluid and provide a large surface area per unit of storage. In the system of the ice storage tank. it is necessary to control the brine outlet temperature at a constant value during the charging and discharging periods. The brine outlet temperature can be controlled by the brine flow rate. To maintain the outlet temperature at aconstant value, the brine flow rate should be regulated with respect to time. For various outlet brine temperatures, values of the flow rate of brine through the tank by the simulations are compared with the data of the manufacturing company, and they are in good agreement

      • 정의적 특성이 수학적 문제 해결력에 미치는 영향

        강호욱,노은환,박은진,송현준,이혜경,주채연 진주교육대학교 초등교육연구소 2005 科學敎育硏究 Vol.28 No.-

        The purpose of this study is to provide some basic data which can be helpful for improving the methods of mathematics teaching-learning emphasizing the affective factors by investigating the effect on affective characteristics and mathematical problem solving ability of the students on the elementary school sixth grade. In order to achieve these purpose, the following research problems were set up for the present study: The results of this study are as follows: First, it was appeared that there was not any difference on attitude on mathematics, belief, self-confidence and the degree of mathematical problem solving ability by sex. Second, it was appeared that there was some statistical meaningful difference on attitude on mathematics, belief, self-confidence and the degree of mathematical problem solving ability according to high middle low ability on mathematics which the students think that they have. Based on the results of this study, I'd like to give some suggestions as followings to provide some help to teaching and learning mathematics. First, the succeeding studies are needed by selecting different population from the population of this study, classifying low-ranking factors consisting of affective characteristics differently from this study, compounding each low-ranking factors in various manners like using new items, etc. Second, the succeeding studies are needed in this part, because what mathematical belief teachers have mathematics can have an effect on students' mathematical belief and action as well as on teachers' thinking process and action in the class. Third, the succeeding studies are needed to develop concrete field study and program which can be helpful for improving actually students' affective behavior characteristics in school field.

      • KCI등재후보

        대동맥 판막 치환술 후 반복되는 Acinetobacter baumannii 균혈증의 원인이 된 대동맥염 1예

        정용필,김성철,송은희,장은영,김은경,김윤지,성흥섭,김미나,최상호,우준희,김양수 대한감염학회 2007 감염과 화학요법 Vol.39 No.3

        감염성 대동맥염은 흔하지 않지만 매우 위중한 질병으로 Salmonella so.와 S. aureus가 주된 원인균이다. 아직까지 병원내 감염의 주요 원인균인 Acinetobacter baumannii에 의한 감염성 대동맥염은 보고된 바가 없었다. 저자들은 대동맥 판막 치환술을 시행받은 76세 남자 환자에서 적절한 항생제 투여에도 반복되는 A. baumannii 균혈증의 원인이 감염성 대동맥염으로 진단되었던 1예를 경험하였기에 보고하는 바이다. Infectious aortitis is an uncommon yet, life threatening disease. Early surgical treatment and prolonged antibiotic therapy is crucial to survival. Salmonella sp. and Staphylococcus aureus are the most common organisms isolated. There is no case report of infectious aortitis caused by Acinetobacter baumannii, which has recently emerged as a major cause of health care-associated infections. Here, we describe a 76-year-old male with infectious aortitis who experienced recurrent bacteremia due to A. baumannii in spite of adequate antimicrobial therapy after aortic valve replacement.

      • SCIESCOPUSKCI등재
      • Hypoxic Conditioned Medium from Human Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Skin Wound Healing through TGF-β/SMAD2 and PI3K/Akt Pathways

        Jun, Eun Kyoung,Zhang, Qiankun,Yoon, Byung Sun,Moon, Jai-Hee,Lee, Gilju,Park, Gyuman,Kang, Phil Jun,Lee, Jung Han,Kim, Areee,You, Seungkwon Molecular Diversity Preservation International (MD 2014 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.15 No.1

        <P>In a previous study, we isolated human amniotic fluid (AF)-derived mesenchymal stem cells (AF-MSCs) and utilized normoxic conditioned medium (AF-MSC-norCM) which has been shown to accelerate cutaneous wound healing. Because hypoxia enhances the wound healing function of mesenchymal stem cell-conditioned medium (MSC-CM), it is interesting to explore the mechanism responsible for the enhancement of wound healing function. In this work, hypoxia not only increased the proliferation of AF-MSCs but also maintained their constitutive characteristics (surface marker expression and differentiation potentials). Notably, more paracrine factors, VEGF and TGF-β1, were secreted into hypoxic conditioned medium from AF-MSCs (AF-MSC-hypoCM) compared to AF-MSC-norCM. Moreover, AF-MSC-hypoCM enhanced the proliferation and migration of human dermal fibroblasts <I>in vitro</I>, and wound closure in a skin injury model, as compared to AF-MSC-norCM. However, the enhancement of migration of fibroblasts accelerated by AF-MSC-hypoCM was inhibited by SB505124 and LY294002, inhibitors of TGF-β/SMAD2 and PI3K/AKT, suggesting that AF-MSC-hypoCM-enhanced wound healing is mediated by the activation of TGF-β/SMAD2 and PI3K/AKT. Therefore, AF-MSC-hypoCM enhances wound healing through the increase of hypoxia-induced paracrine factors via activation of TGF-β/SMAD2 and PI3K/AKT pathways.</P>

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