한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

複合 韓藥劑 淸籬滋坎湯의 抗癌效果 및 作用機轉 糾明

Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.

컴포넌트 기반 소프트웨어 프로덕트 라인에서의 가변성

최승훈 덕성여자대학교 자연과학연구소 2004 자연과학 논문집 Vol.10 No.-

보다 신뢰성 있는 소프트웨어를 단시간 내에 개발하기 위한 방법으로서 최근에 소프트웨어 프로덕트 라인에 대한 연구가 활발히 진행 중이다. 소프트웨어 프로덕트 라인의 목적은, 미리 구축된 부품들을 소프트웨어 생산시 정해진 방식에 의해 조립함으로써 비슷한 특성을 가지고 있지만 특정 부분이 다른 일련의 소프트웨어들을 보다 빠르게 생산하는데 있다. 소프트웨어 프로덕트 라인을 구축하는데 있어서의 가장 중요한 부분은, 핵심 소프트웨어 자산을 개발하기 위한 기술과 소프트웨어 부품을 조립하여 구체적인 소프트웨어 시스템을 생산하는 기술이다. 핵심 소프트웨어 부품 개발과 조립을 효율적으로 지원하기 위해서는, 소프트웨어 분석 및 설계 단계, 나아가서는 소프트웨어 개발 전 단계에 걸쳐서 제품군에 속하는 멤버들 사이의 차이점을 모델링하고 체계적으로 관리해야 한다. 본 논문에서는 컴포넌트 기반 소프트웨어 프로덕트 라인에서의 가변성을 명 확히 표현하고 지원하기 위한 모델링 기법을 제안한다. 본 논문에서 가변성은, 소프트웨어 아키텍처 상에서의 가변성과 소프트웨어 컴포넌트 상에서의 가변성 으로 분류되며, 변경 지점으로 표현된다. 본 논문의 연구 결과는 소프트웨어 프로덕트 라인을 구성하는 핵심 요소인 소프트웨어 아키텍처와 소프트웨어 컴포 넌트 개발시 가변성을 지원하기 위한 기술 개발에 활용될 수 있다.

제주지역 수출돈의 현황 및 생산농가의 경영분석

최승준,강태숙 濟州大學校 農科大學 動物科學硏究所 1999 動物科學論叢 Vol.14 No.1

This study was conducted to investigate the current circumstances of pork exports and to find some problems relevant to pork exports in Cheju province. Twenty-one hog farms producing hogs exported and three pork processing companies were surveyed their management status. The amount of pork export has steadily increased since 1993(93MT) through 1997(875M/T) in Cheju. The rate of producing standardized pork for export was much higher in Cheju province(46.4%) than in mainIand(33.5%), mainly due to lower rate of uncastrated pigs. Average production cost per marketing pig showed big differences between farms, ranging from 180,000 won to 198,000 won. Net income per marketing pig also ranged from -1,644 won to 15,891 won. Average litter and weaning heads per sow was 10.7 and 8.8, respectively, and feeding duration for the market outlet was required 179 days. Most farmers were purchasing their breeding stock from various sources including the own farm. The mating system showed big difference between farms, and farmers were using various breeds as a terminal sire. All pork processing companies contrated with hog farmers to pay the average price of three domestic pig markets for their purchasing pigs regardless of pork grade. Farmers tended to prefer domestic market to export because they can get money according to pork grade. Our data indicate that there are many problems to solve in improving management status, purchasing breeding stock and uniting the mating system in order to increase the rate of standardized pork and the amount of pork export.

다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.

신생검증례에 의한 사구체신질환의 분석

최두환,구시선,배승훈,박병현,안선호,송주흥 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.2

To elucidate the incidences and the clinical characteristics of glomerular diseases in our hospital, we reviewed the clinical records and histological findings of the 117 cases, which were diagnosed as one of the glomerular disease in renal biospy for about 6 years since 1991. In these 117 cases, 74 cases (63.2 %) fell into primary glomerulonephritis(GN), 18 cases (15.4%) into secondary GN, 2 cases (1.7 %) into end stage kidney, 4 cases (3.4%) into tubulointerstitial disease and the biopsy samples were inadequate for diagnosis in 19 cases. In primary glomerular diseases, most common pathologic diagnosis was IgA nephropathy (36.5 %}, followed by minimal change nephrotic syndrome (29.7%). The incidence of IgA nephropathy would be increased if we had biopsied every asymptomatic urinary abnormality (AUA) patients. Systemic lupus erythematosus (SLE) . hepatitis B accounted for most of secondary GN in our cases. One case of progressive scleroderma was included in this secondary GN. Minimal change nephrotic syndrome (22 cases) was the most common cause of nephrotic syndrome, followed by membranous GN (9 cases) and IgA nephropathy (8 cases). 2 cases of primary amyloidosis were presented with nephrotic syndrome. Nephrotic syndrome as presenting symptom in our IgA nephropathy patients was higher than in other studies, which may be due to indication bias for renal biopsy. We suggest that renal biopsy should be done in adult nephrotic syndrome and in SLE, because various kind of glomerular diseases can develop nephrotic syndrome in adult, renal biopsy can affect the treatment and prognosis in each patients and renal biopsy also determines the extent of renal involvement in SLE on which the treatment depends. In AUA urinary patients, renal biopsy could be reserved for the patients who show declining of GFR or rising of proteinuria. Because IgA nephropathy account for most of AUA. and there is no specific treatment for IgA nephropathy, and renal biopsy in those cases is helpful in ruling out the patients who need no treatment.

차체 구조의 빔모델링에 관한 연구

최종근,이승훈,최석환 도립 강원전문대학 1998 道立 江原專門大學 論文集 Vol.1 No.1

This paper has been studied to analyze an automotive body structure by means of a simplified beam model rather than a detailed shell model. It has been done to enhance analysis performance to facilitate design changes. Basically automotive body consists of box channel structures and the strain energy for deformation is concentrated in the vicinity of joint area. Therefore analysis errors from beam modeling are due to the difference in strain energy of joint area between beam and shell modeling. Technique using modified section properties has been introduced, and some important nondimensional factors have been also introduced. We have found out the ratio of thickness and section length, t/H is the main factor to decide whether we have to use this new technique in beam modeling of box channel structures with joint. This technique shows the same results from shell modeling within 2 % error, both in static and normal mode analysis for an isolated model.

黃帝內經에서의 瘀血의 認識에 對한 理論的 硏究

崔昇勳 大田大學校 1987 論文集 Vol.6 No.2

소프트웨어 제품 라인에서 JESS 규칙 기반 시스템을 이용한 특성 구성 검증

최승훈 德成女子大學校 2007 德成女大論文集 Vol.36 No.-

특성 모델(Feature Model)은 소프트웨어 제품 라인 개발 시 도메인 공학단계에서 가장 널리 사용되는 모델로서, 특정 도메인에서 제품들 사이의 공통된 개념들과 서로 다른 개념들을 모델링하는데 사용된다. 구체적인 제품 생산시 특성 모델에서 특정 제품에 포함될 특성들을 선택한 결과를 특성 구성 (Feature Configuration)이라고 하며, 이것은 특정 제품에 대한 요구 사항을 나타낸다. 현재 소프트웨어 제품 라인 개발 시 특성 모델을 어떻게 구축하고 이용하는지에 대한 연구는 많이 되어 있지만, 특성 모델 및 특성 구성에 대한 정형적 모델과 논리적 추론에 대한 연구는 부족하다. 본 논문에서는 자바 언어로 구현된 규칙 기반 시스템인 JESS를 이용하여 특성 모델에 표현되어 있는 특성 및 특성들 사이의 관계/제한 조건을 JESS 언어로 정의하고 JESS가 제공하는 규칙 엔진을 이용하여 특성 구성의 불일치성(inconsistency)을 검증하는 방법을 제안한다. 본 연구는 자바 언어와의 결합성이 뛰어난 JESS 시스템에 기반을 두었기 때문에 다른 소프트웨어 개발 환경과 쉽게 통합될 수 있다.