혼합형 검사에서 IRT문항모수와 기저 능력분포의 동시 추정이 문항모수 추정의 정확도에 미치는 영향

김성훈(Seonghoon Kim) 한국교육평가학회 2013 교육평가연구 Vol.26 No.3

본 연구는 김성훈(2012)의 후속연구로서, 혼합형 검사의 IRT 문항모수를 주변최대우도(MML)/베이지언 최빈치(BM)방법을 통해 추정할 때 사전능력분포를 ‘표준정규 N(0, 1)분포로 지정하는 방식’보다 ‘기저 능력분포의 추정치로 지정하는 방식(즉, 문항모수와 능력분포를 동시에 추정하는 방식)’이 더 우수한지를 모의실험을 통해 확인하고자 하였다. PARSCALE프로그램을 이용하여 혼합형 검사의 선다형 문항은 3모수 로지스틱(3PL)모형으로 분석하고 구성형 문항은 일반화부분점수(GPC)모형으로 분석하였다. 모의실험의 요인으로 기저 능력분포의 유형, IRT분석 모형에 의한 검사의 유형, 검사의 곤란도, 표본의 크기 등을 포함하였다. 김성훈(2012)의 연구 결과와 유사하게, 사전능력분포를 기저 능력분포의 추정치로 지정하는 방식이 디폴트 방식인 N(0, 1)분포로 지정하는 방식보다 고려된 모든 검사 조건에서 우수하거나 대등한 수행을 보였다. 즉, 선다형 검사뿐만 아니라 혼합형 검사에 대해서도 IRT 문항모수와 기저 능력분포의 동시 추정은 문항모수 추정의 정확성과 안정성을 향상시켰다. In item response theory (IRT), the use of marginal maximum likelihood (MML) and Bayesian modal (BM) methods for item parameter estimation requites the specification of a prior distribution for the ability variable. With multiple-choice (MC) tests, Kim (2012) found that in MML/BM estimation of item parameter; the way of specifying the prior ability distribution as the estimate of underlying distribution (i.e., concurrent estimation of item parameters and underlying distribution) outperformed or peformed equally to the way of specifying the prior ability distribution as a standard normal N(0, 1) distribution. As a follow-up study of Kim (2012), this paper attempted to verify through simulations that the previous findings from Me tests should be generalized to mixed-format tests consisting of MC items and constructed-response (CR) items. The PARSCALE program was used to analyze MC and CR items via the 3-paramerer logistic (3PL) and generalized partial credit (GPO models, respectively. The simulation factors considered include type of underlying ability distributions (normal, positively skewed, and negatively skewed), test type by the IRT model used OPL, GPC, and 3PL+GPC), test difficulty (easy, moderately difficult, and difficult), and sample size (500 and 2,000). As found in Kim's study, the way of concurrently estimating the underlying distribution along with item parameters outperformed or peformed equally to the way of specifying the prior distribution as a N(0, 1) in accurate estimation of item parameters with mixed-format tests.

하천유역조사의 장기유출분석 과정 소개

김성훈,김선우,김태정,이성호,성장현,이연길,Kim, Seong-Hun,Kim, Seon-U,Kim, Tae-Jeong,Lee, Seong-Ho,Seong, Jang-Hyeon,Lee, Yeon-Gil 한국수자원학회 2020 물과 미래(한국수자원학회지) Vol.53 No.7

열간가압소결법으로 제조한 탄화규소의 균열자기치유 특성

김성훈,김경훈,도환수,박주석,김경자,심광보,Kim, Seong-Hoon,Kim, Kyung-Hun,Dow, Hwan-Soo,Park, Joo-Seok,Kim, Kyung-Ja,Shim, Kwang-Bo 한국결정성장학회 2016 韓國結晶成長學會誌 Vol.26 No.2

본 연구에서는 열간가압소결법으로 SiC를 소결하여 균열자기치유 특성을 분석하였다. SiC는 $Al_2O_3$와 $Y_2O_3$를 소결조제로 $1950^{\circ}C$, 50 MPa, 아르곤(Ar) 분위기에서 소결하였다. 소결된 시편을 $3{\times}4{\times}40mm$, 절단 및 가공하고, Vickers 경도기를 이용하여 49.6 N으로 예비균열을 생성하였다. $1200{\sim}1400^{\circ}C$, 1~10시간 산화분위기에서 열처리한 후 XRD, SEM, 3점 굽힘강도를 측정하였다. $1300^{\circ}C$ 1시간에서 741 MPa, 5시간에서 770 MPa로 가장 우수한 균열자기치유 효과를 나타내는 것으로 분석되었다. In this study, it was investigated that characteristic of crack-self-healing of hot-pressed SiC. SiC ceramics was sintered with $Al_2O_3$ and $Y_2O_3$ sintering additive by hot press. Sintering was performed in hot-press furnace in flowing argon (Ar), holding for 3 hr under $1950^{\circ}C$ and 50 MPa. The sintered SiC was machined into 3-point bending strength specimen of $3{\times}4{\times}40mm$, and introduced pre-crack by Vickers indentation at 49.6 N. Specimens were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM), 3-point bending strength after heat treatment at $1200{\sim}1400^{\circ}C$ for 1~10 hr. The best crack-self-healing ability was achieved 770 MPa 3-point bending strength by heat treatment at $1300^{\circ}C$ for 5 hr.

부신의 기능성종양 및 비기능성 부신피질선종을 제외한 부신 양성종양에 대한 임상적 고찰

김성훈,이준호,김지수,최준호,남석진,이정언,김석원,길원호,김정한,Sung Hun Kim,Jun Ho Lee,Jee Soo Kim,Jun-Ho Choi,Seok-Jin Nam,Jeong-Eon Lee,Seok Won Kim,Won Ho Kil,Jung-Han Kim 대한갑상선-내분비외과학회 2014 The Koreran journal of Endocrine Surgery Vol.14 No.4

Purpose: Benign adrenal tumors other than hyper-functioning tumor and non-functioning cortical adenoma are extremely rare. The purpose of this study is to review the clinical features of these rare benign adrenal tumors and to analyze their prevalence and the proper surgical approach for them. Methods: Among patients who underwent adrenalectomy in Samsung Medical Center, between 1997 and 2013, patients with benign adrenal tumor except non-functioning cortical adenoma, malignancy, and hyper-functioning tumor such as pheochromocytoma, aldosteronoma, and cortisol producing tumor were included. Clinical details, radiologic findings and pathologic findings as well as data associated with the surgical procedure were analyzed retrospectively. Results: The percentage of these tumors among 703 surgically removed adrenal tumors was 10.7% (75 cases). They included 30 adrenal cysts, 18 ganglioneuromas, 11 myelolipomas, seven schwannomas, and the other six were rare adrenal tumors. Approximately 40% of the patients were operated under a diagnosis different from original tumors. Operation time and hospital stay of patients who underwent laparoscopic adrenalectomy were shorter than those of patients who underwent open adrenalectomy. Conclusion: These benign adrenal tumors are very rare and difficult to diagnose preoperatively. For the surgical treatment of these tumors, laparoscopic adrenalectomy is more preferable to conventional open adrenalectomy.

SELECT 모델을 이용한 트롤 비교 시험조업법에 의한 망목 선택성에 관한 연구

김성훈,김형석,백세나,김재형,김병관,Seonghun KIM,Hyungseok KIM,Sena BAEK,Jaehyung KIM,Pyungkwan KIM 한국수산해양기술학회 2023 수산해양기술연구 Vol.59 No.2

In this study, a comparative test operation was conducted through the alternate haul method to examine the selectivity of the four mesh sizes (60 mm, 90 mm, 110 mm, and 130 mm) of the trawl codend. The selectivity was analyzed using the SELECT model considering the fishing efficiency (split parameter) of each fishing gear in the comparative test fishing operation in the trawl and the maximum likelihood method for parameter estimation. A selectivity master curve was estimated for several mesh sizes using the extended-SELECT model. As a result of analyzing the selectivity for silver croaker based on the results of three times hauls for each experimental gear, it was found that the size of the fish caught increased as the size of the mesh size increased. When the selectivity for each mesh size analyzed by the SELECT model considering the split ratio was evaluated based on the size of the AIC value, the estimated split model was superior to the equal split model. Based on the master curve, the 50% selection length value was 2.893, which was estimated to be 136 mm based on the mesh size of 60 mm. In some selectivity models, there was a large deviance between observed and theoretical values due to the non-uniformity of the distribution of fished length classes. As a result, it is considered that appropriate sea trials and selectivity evaluation methods with high reliability should be applied to present trawl fishery resource management methods.

열통합 기법을 통한 이산화탄소 막 분리공정 에너지 해석

김성훈,김태영,김범석,조현준,여영구,Kim, Seong Hun,Kim, Tae Yong,Kim, Beom Seok,Cho, Hyun-Jun,Yeo, Yeong Koo 한국플랜트학회 2016 플랜트 저널 Vol.12 No.2

이산화탄소 분리공정에 있어서 분리막 공정은 소형, 모듈성, 설치의 용이성, 작동의 유연성, 낮은 설치 비용 및 낮은 에너지 소비량 등의 장점들로 인하여 주목 받고 있다. 본 연구에서는 실험데이터와의 비교를 통해 교차흐름, 병류흐름, 향류흐름 3가지 모델의 정확도를 알아보았다. 실험에서 이용된 이산화탄소 분리공정을 가장 잘 나타내어주는 모델을 토대로 전산모사를 통하여 2단 막 분리 구조에서의 운전조건을 규명하고 분리막의 투과도 및 선택도가 분리성능에 미치는 영향을 알아보았다. 나아가 수증기 sweep을 이용하는 2단 막 분리 구조에서 열교환망 합성기법을 적용하여 열교환기 도입에 따른 소요 전력의 변화와 운전비용 절감효과를 살펴보았다. The membrane separation processes have received attention due to advantages such as compactness, modularity, ease of installation, flexibility of operation, lower capital cost and lower energy consumption. In this study, we evaluated accuracy of cross-flow, co-current and counter-current models. With the most accurate model, we identified the operating conditions of the two-stage membrane separation and examined the effects of permeance and selectivity of the membrane by simulation. Futhermore, power requirements and operating cost savings due to the introduction of the heat exchanger were investigated by applying heat exchanger network synthesis technique in the two-stage membrane separation using vapor sweep.

교배조합에 따른 번식성적

김성훈,Kim, Seong-Hun 대한양돈협회 1992 養豚 Vol.14 No.11

Enhancement of Low Temperature Selective Deposition of Diamond Film

김성훈,Kim, Sung Hoon Korean Chemical Society 2001 대한화학회지 Vol.45 No.3

Structure of [$CoL_2(MeOH)(NO_3)_2$] [L = N1-(1-(pyridin-4-yl)ethylidene)naphthalene-1,5-diamine)]

김성훈,허현수,이순원,Kim, Sung-Hoon,Huh, Hyun-Sue,Lee, Soon-W. Korea Crystallographic Association 2007 韓國結晶學會誌 Vol.18 No.1

Dipyridyl 리간드 L'(N,N'-bis-(1-pyridin-4-yl-ethylidene)-naphthalene-1,5-diamine)을 함유한 $CH_2Cl_2$ 용액을 $Co(NO_3)_2{\cdot}6H_2O$을 함유한 MeOH 용액 위에 깔았을 때, 배위 고분자가 아닌, 분자성 코발트 화합물 [$CoL_2(MeOH)(NO_3)_2$] (1)이 형성되었다. 화합물 1의 X-ray 구조 분석 결과, 이 화합물은 pyridyl-amine 리간드 L(N1-(4-Imino-1-methyl-but-2-enylidene)-naphthalene-1,5-diamine)을 함유하고 있었다. 반응 중에 리간드 L'이 리간드 L로 가수분해되었다는 것을 화합물 1의 구조가 강하게 암시하고 있다. When a $CH_2Cl_2$ solution of the dipyridyl species L' (N,N'-bis-(1-pyridin-4-yl-ethylidene)-naphthalene-1,5-diamine) was layered onto the top of a MeOH solution of $Co(NO_3)_2{\cdot}6H_2O$, a molecular cobalt compound [$CoL_2(MeOH)(NO_3)_2$] (1), not a coordination polymer, was formed. X-ray structural analysis of compound 1 revealed that it contains the pyridyl-amine ligand L (N1-(4-imino-1-methyl-but-2-enylidene)-naphthalene-1,5-diamine), instead of L'. Structure of compound 1 strongly suggests that the original ligand L' has been hydrolyzed to ligand L during the reaction.

A Case of End-Stage Renal Disease with Joubert Syndrome due to CEP290 Mutation

김성훈,이상택,성문우,김만진,이준화,Kim, Sung Hoon,Lee, Sang Taek,Seong, Moon-Woo,Kim, Man Jin,Lee, Jun Hwa The Korea Society of Inherited Metabolic Disease 2020 대한유전성대사질환학회지 Vol.20 No.1

쥬버트 증후군(JS, Joubert syndrome)은 대부분 상염색체 열성으로 유전되는 유전성 대사질환으로 임상증상은 신생아 시기부터 발현된다. 저자들은 신생아기부터 특징적인 임상 증상이 순차적으로 발현되어 임상적으로 JS를 의심하였으나 특징적인 뇌 MRI 소견인 molar tooth sign (MTS)이 늦게 나타난 후 전장엑솜분석(WES, whole exome sequencing)으로 확진 된, 말기 신부전을 동반한 JS 1례를 경험하였기에 보고하고자 한다. 14세 남자 환자는 출생 직후 반복적인 무호흡과 과호흡으로 치료받은 병력이 있으며, 생후 8개월때부터 전반적 발달 지연과 관련되어 처음 병원을 방문하여 기본적인 발달 지연에 관한 검사를 시행하였으나 특이 소견 없었고, 이후 15개월 때 근육생검을 포함한 여러 검사를 통해 사립체(mitochondrial) 질환으로 진단 되었었다. 이후 물리 치료만 하며 관찰 하던 중 안구진탕과 망막질환이 확인되었다. 생후 7세 8개월에는 처음 발작이 있었으며, 말기 신부전이 있어 8세부터 혈액투석을 시작한 후, 혈액 투석 직후 수차례 발작이 있었으나 전해질 불균형으로 인한 발작으로 진단하여 항뇌전증 약물 치료는 하지 않았다. 9세 4개월 때 고혈압으로 인한 뇌출혈로 치료 받았으며, 이때 시행한 뇌 CT상 MTS가 처음 의심되었다. 13세 10개월에 시행한 뇌 MRI 검사상 MTS가 명확히 확인되었고, 전장엑솜 분석으로 JS의 CEP290 mutation (c.6012-12T>A)이 확인되었다. 환자는 신생아기부터 발현된 특징적인 임상 소견과 말기 신부전 상태, 뇌 CT 또는 MRI소견, 그리고 전장엑솜분석 검사로 JS로 확진하였다. JS는 임상 양상이 다양할 뿐만 아니라 진단에 중요한 MTS 소견이 초기에 보이지 않더라도, 임상적으로 의심된다면 확진을 위해서 전장엑솜분석을 시행하는 것이 필요하다. Joubert syndrome (JS) is a rare genetic disorder that is characterized by ataxia, hypotonia, developmental delay, respiratory abnormalities such as apnea-hyperpnea, and abnormal eye movements. The pathognomonic diagnostic finding is the "molar tooth sign" (MTS) on brain magnetic resonance imaging (MRI), described as cerebellar vermis hypoplasia or dysplasia, thick and horizontally oriented superior cerebellar peduncles, and an abnormally deep interpeduncular fossa. JS is characterized by genetic heterogeneity: pathogenic variants in over 30 genes have been identified to date. The CEP290 protein, which is on chromosome 12q21.3, is most frequently mutated in patients with JS, especially with renal involvement. Here, we report a case of JS in a 14-year-old male patient with end-stage renal disease. To the best of our knowledge, this is the first Korean report of a patient with JS due to CEP290 mutation (c.6012-12T> A) whose diagnosis was confirmed after repetitive MRI. We suggest consultation with an experienced neuro-radiologist and follow-up MRI studies to detect a "hidden" MTS if clinical findings suggest a diagnosis of JS. Furthermore, even in the absence of an MTS, whole exome sequencing should be considered.