시간의 흐름에 따른 핸드폰의 품질동태성에 관한 연구

윤성필(Sung-Pil Yoon),임성욱(Sung-Uk Lim),박만희(Man-Hee Park),조인희(In-Hee Cho) 한국엔터테인먼트산업학회 2010 한국엔터테인먼트산업학회논문지 Vol.4 No.3

본 연구는 선행연구에서 조사된 핸드폰의 고객요구속성을 Kano 모델의 품질특성에 적용하여 시간의 흐름에 따라 어떤 변화가 있는지를 살펴보고자 한다. 또한 고객들의 새로운 요구속성이 나타났는지도 함께 살펴보고자 한다. 많은 문헌과 선행연구에서 나타나고 있는 시간에 따른 품질특성의 이동이 매력적 품질에서 일원적 품질로 일원적 품질에서 당연적 품질로 변화하는 진부화(陳腐化)현상이 나타나는지도 함께 살펴보고자 한다. In this study, previous research (Sung-Uk Lim, 2004) surveyed in customer demand for mobile phones the quality characteristics of properties applied to the Kano model, the flow of time, depending on whether any changes will be discussed. In addition, our customers" new requirements will be examined along with the property map appeared. The movement of time-dependent quality characteristics appeared in many previous studies Obsolescence Phenomenon - from Attactive Quality Element to One-Dimensional Quality Element, from One-Dimensional Quality Element to Must-Be Quality Element - may appear be examined together.

12-O-Tetradecanoylphorbol-13-Acetate에 의한 HL-60 세포 분화유도중 Vimentin 유전자 전사조절에 대한 AP-1의 역할

임규,김진희,권도원,김승민,이명선,윤경아,손미영,박종일,윤완희,황병두 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

Purpose: To gain insight on the role of AP-1 in transcriptional regulation of vimentin gene during differentiation of HL-60 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA), the levels of vimentin mRNA and AP-1 have been investigated with Northern blot hybridization and DNA mobility shift assay. Materials and Methods: HL-60 cells were grown in RPMI 1640 medium supplemented with 10% heat-inactivated fetal calf serum and antibiotics in a humidified 5% CO_2 at 37℃. Total RNA was prepared by a modification of the method of Karlinsey et al. Northern blot hybridization was performed by the method of Virca et al. EcoRI fragment of pVIM-GEM was used as probe for vimentin mRNA. DNA mobility shift assay was performed by the method of Lim et al. End labeled DNA probe(Upper strand, 5'-CGCTTGATGAGTCAGCCG- 3') for AP-1 binding activity was mixed with nuclear extracts in a 20 μl reaction volume containing 300 mM KCI, 60 mM HEPES, pH 7.9, 25 mM MgCI_2, 1 mM EDTA, 1 mM DTT, 60% glycerol, and 2 ㎍ of poly[dI-dC]. Results: TPA increased vimentin mRNA levels, with maximal stimulation reached at 24 hr. The level of vimentin mRNA was induced in proportion to the concentration of TPA. TPA-induced vimentin mRNA was almost reduced by actinomycin-D pretreatment. TPA-induced stimulation of vimentin gene was completely reduced by staurosporin pretreatment. In DNA mobility shift assay, AP-1 newly appeared at 24 hr during TPA-induced differentiation and was almost not detected after the pretreatment of staurosporin. Conclusions: These results suggest that the induction of vimentin mRNA during TPA-dependent differentiation in HL-60 cells may be mediated by protein kinases C signal transduction and AP-1 is important to transcriptional regulation.

농흉과 종격동염이 합병된 viridans streptococcus에 의한 인후농양 1예

임상현,유진홍,권순석,김연식,신완식,강문원,정명희 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.2

최근 저자들은 viridans streptococcus에 의한 인후농약으로 인하여 발생한 종격동염 및 농흉을 보인 47세 여자 환자를 적절한 배농과 항생제로 치료한 국내 최초의 1예를 치험하였기에 문헌 고찰과 함께 보고하는 바이다. Since the antibiotic era, retropharyngeal abscess became a rare disease entity nowadays. But it may often progress to lethal complications involving vital structure if diagnosis or treatment is delayed. We experienced a case of empyema and mediastinitis complicating retropharyngeal abscess caused by viridans streptococcus in a 47-year-old female patient with diabetes mellitus. She was successfully treated with appropriate antibiotic therapy combined with percutaneous abscess drainage. To our knowledge, such a complication of retropharyngeal abscess has not been reported in Korea yet and we present this unusual case herein followed by a review of the related literature.

한국인 파킨슨병에서 Monoamine Oxidase B 유전자와 Cytochrome P450IID6 유전자의 다형성

이용희,임정근,이상도,이영재 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

12-O-Tetradecanoylphorbol-13-Acetate에 의한 HL-60 세포 분화유도중 Vimentin 유전자 전사조절에 대한 AP-1의 역할

임규,김진희,권도원,김승민,이명선,윤경아,손미영,박종일,윤완희,황병두 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

Purpose: To gain insight on the role of AP-1 in transcriptional regulation of vimentin gene during differentiation of HL-60 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA), the levels of vimentin mRNA and AP-1 have been investigated with Northern blot hybridization and DNA mobility shift assay. Materials and Methods: HL-60 cells were grown in RPMI 1640 medium supplemented with 10% heat-inactivated fetal calf serum and antibiotics in a humidified 5% CO_(2) at 37°C. Total RNA was prepared by a modification of the method of Karlinsey et al. Northern blot hybridization was performed by the method of Virca et al. EcoRI fragment of pVIM-GEM was used as probe for vimentin mRNA. DNA mobility shift assay was performed by the method of Lim et al. End labeled DNA probe(Upper strand, 5'-CGCTTGATGAGTCAGCCG- 3') for AP-1 binding activity was mixed with nuclear extracts in a 20 μl reaction volume containing 300 mM KC1, 60 mM HEPES, pH 7.9, 25 mM MgCl_(2), 1 mM EDTA, 1 mM DTT, 60% glycerol, and 2μg of poly[dI-dC]. Results: TPA increased vimentin mRNA levels, with maximal stimulation reached at 24 hr. The level of vimentin mRNA was induced in proportion to the concentration of TPA. TPA-induced vimentin mRNA was almost reduced by actinomycin-D pretreatment. TPA-induced stimulation of vimentin gene was completely reduced by staurosporin pretreatment. In DNA mobility shift assay, AP-1 newly appeared at 24 hr during TPA-induced differentiation and was almost not detected after the pretreatment of staurosporin. Conclusions: These results suggest that the induction of vimentin mRNA during TPA-dependent differentiation in HL-60 cells may be mediated by protein kinases C signal transduction and AP-1 is important to transcriptional regulation.

RF-Module 과 FSK Modem을 이용한 원거리 전광판 제어 시스템의 구현

임성준,황희융,강박광 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

최근 많은 분야에서 사용되고 있는 소형 전광판을 이용하여 원거리에서도 메시지 전달이 가능한 광고용 전광판을 제작하였다. FSK Modem과 RF-Module을 이용하여 실시간으로 광고의 내용을 바꾸는 것을 원칙으로 구현하였다.

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

蟠蔥散의 適應病理와 臨床活用에 關한 小考

林樂哲,金聖勳,金東熙,全基石 대한동의병리학회 1998 동의생리병리학회지 Vol.12 No.2

蟠蔥散은 《太平惠民和劑局方》에 收載된 이래, 胃腸, 少腹(下腹部), 前陰, 子宮 等의 虛寒(虛冷)性 症狀과 少陰人 裏寒證 等에 應用되고 있다. 蟠蔥散을 投與한 患者 106例를 對象으로 性別 및 年齡分布, 投與量, 處方構成, 症狀의 頻度 및 症候 分析을 한 결과 總 患者中 女子患者가 男子에 比하여 월등히 많았고, 投與 分量은 成人은 20貼 以內가 가장 많았으며 症狀의 頻度는 腹痛(右側下服痛, 小腹痛, 胃酸痛, 産後腹痛), 生理痛, 腰痛, 過敏性腸症候群, 不姙, 冷帶下順으로 나타났다. 本 方의 適應症은 虛冷에서 오는 疝氣作痛을 비롯해서 胃腸疾患, 胸脇背項에 連한 拘及痛, 小腹이나 外腎의 腫刺痛, 婦人의 子宮系疾患等으로 要約할 수 있으며, 特히 少腹冷痛과 四象 體質中 少陰人의 裏寒證에 效果的이었다. To use effective application of Ban Chong San(BCS) effectively, bibliographical study of BCS and clinical evaluation of BCS on distribution of sex, age, frequency of treatment and changes of symptoms of 106 patients treated with BCS from 1997. 9. 1. to 1997. 12. 31 at my clinic. The result were summarized as follows. 1. Among total 106 patient, a number of women and men were 90 (85%) and 16(15%) respectively 2. The number of children was 8.(7.5%) 3. Approximately, BCS was administrated to the adults for 10 days, 20 chups. 4. Chief symptoms were abdominal pain right abdominal pain, lower abdominal pain, stomachache, postpartal abdominal pain, menstrual pain, lower back pain, hypersensitive intestine syndrome, sterility, leucorrhea. 5. BCS can be effective in stabbing pain, gastric disease, terrible pain, connected chest back, stabbing pain of lower abdominal region or kidney region and uretus disease of women : induced by cold.

우관상동맥 개구부 완전 폐쇄가 동반된 대동맥 판상부 협착증 1례

임상현,김종진,김희열,진승원,전희경,노태호,채장성,김재형,홍순조,최규보,윤정섭,김치경 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

방사선 센서의 동작특성

임영화,한상효,김도성,강희동 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

A Geiger-M□ller(GM) radiation sensor is fabricated by using the vacuum system and gas feeding system. The base pressure of the vacuum system is 1X10^(-7)torr, and two MFCs(0~10sccm, ±1% accuracy of the full scale) are used to control the composition of filling gas exactly. The fabricated GM radiation sensor is simultaneously filled with the mixture of neon and clorine. The mica window(7.43mg/cm^(2)) is attached to the GM radiation sensor. The optimized GM radiation sensor has about 660V starting voltage, 125V plateua length, and 10%/100V plateau slope.