HPLC/FLD를 이용한 성별·연령별 혈장 homocysteine 정상치 조사

이경옥,류광석,이규범,이경옥,류광석,이규범 대한임상검사정도관리학회 1999 臨床檢査와 精度管理 Vol.21 No.1

정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여

신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.

화학적 요부 교감신경절 차단에서 한 분절 차단과 두 분절 차단의 비교

김종일,이규종,이상곤,민병우,반종석,문철준 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4

Chemical Lumbar Sympathetic Block: Comparison of One- Versus Two-needle Techniques Chul-Jun Mun, M.D., Kyu-Jong Lee, M.D., Sang-Gon Lee, M.D., Jong-Il Kim, M.D.^* Jong-Suk Ban, M.D., and Byung-Woo Min, M.D. Department of Anesthesiology, Fatima Hospital, Daegu, Korea ^*Kim Jong Il Pain Clinic, Daegu, Korea Background: It was frequently noticed in the course of performing a two-needle sympathectomy, that satisfactory spread of contrast solution could be produced by injection through only one of the needles. This led to a closer examination of the merits of single-needle technique. Methods: Forty patients were randomized into two groups. Patients in the single-needle group (n = 20) were injected at the second or third lumbar sympathetic ganglia, while patients in the two-needle group (n = 20) were injected at the second and thired lumbar sympathetic ganglia. Lumbar sympathetic blocks were performed using 3 ml of alcohol and the spread of injectate was verified with C-arm fluoroscopy. The indicators of a successful sympathetic block are increasing skin temperature, decreasing pain, and anhidrosis in the distal extremity. Results: The duration of anhidrosis was 12.2 ?? 2.6 months (mean ?? SD) in the single-needle group versus 13.6 ?? 3.6 months (mean << SD) in the two-needle group. Conclusions: As these results were not significantly different from those obtained in patients having considered to be effective for a neurolytic ;i,bar sympathectomy. (korean J Anesthesiol 2001; 41: 439~443)

高等學校 地區科學 敎育의 方向 設定

이규석,우종옥 한국교원대학교 과학교육연구소 1992 청람과학교육연구논총 Vol.2 No.1

본 연구는 과학의 본질과 내용, 그 간의 科學科 敎育 및 地球科學 敎育의 變遷, 地球科學의 학문적 구조, 學校 敎師들의 의견 등을 고찰하여 앞으로의 地球科學 敎育의 方向을 설정하는데 그 목적이 있다. 앞에서 제시한 硏究 目的을 達成하기 위한 본 연구의 주된 방법은 文獻 分析이다. 그리고 敎師에 대한 設問紙 調査등의 資料를 통해 연구 목적에 접근함으로서 妥當性과 實證性을 높이도록 經驗的 接近 方法을 아울러 사용 하였다. 본 연구의 연구 절차는 다음과 같다. 첫째, 과학의 본질과 과학과 교육의 목표와 내용을 고찰하여 봄으로서 地球科學科 敎育의 성격을 정리한다. 둘째, 과학교육의 태동과 변천 및 지구과학의 변천을 역사적으로 조명하여 장래 地球科學의 방향에 대한 시사점을 얻는다. 셋째, 우리나라의 地球科學 敎師가 생각하는 地球科學科 교육의 목표, 내용 및 방향을 조사하여 이를 방향 설정의 자료로 삼는다. 이상 세가지 결과를 토대로 高等學校地球科學科 敎育의 방향을 논의하고 그 결과를 정리 하였다. 高等學校 地球科學 敎育에서는 ① 地球科學的 知識 ② 地球科學的 탐구 방법 ③ 科學的 態度 ④ 地球科學의 발달과 그 이용 등이 강조 되어야 한다. 또한 ⑤ 地球科學의 교육적 특성이 고려되어야 한다. This paper was made for the purpose of research for direction on earth science subject matter of high school in Korea. For this purpose, we 1) reviewed the essence of science and goals and contents of science education, 2) reviewed the change of education of earth science subject matter, 3) investigated earth science teacher's opinion by questionaire. The results were as follows: 1. Earth science subject matter must provide to students scientific process and knowledge -Process: to promote student's concerns for an interest in nature surrounding them, to help students develop and method in solving problems and its application for problem solving, recognition of variables of scientific method, to promote fundamental experiment and skills for scientific inquiry, etc. -Knowledge: provide systematic knowledge than simple rote, to help students understand concepts of recent scientific knowledge, contain's STS, etc. 2. Earth science education must consider educational philosophy and educational psychology: education of scientific literacy, partial professional education, conformity of development stage, sequence between school levels, attitudes to adaptation of scientific knowledge, method, skills and problem solving toward future positive attitudes to science, moral sense of science, minimum essense and difference of lines, open of upper limit, understanding the specific character of earth science, scientific knowledge development continuously, relationships of other subject matter, etc.

전립선 비대 증상 자각군과 일반 남성군의 전립선 비대 증상, 일상생활 활동, 성생활 만족 및 안녕감 비교

이규은,오점숙,김현주,김남선 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: This study was designed to explore and compare the prostatic hypertrophoc symptoms, activities of daily living, satisfaction of sexual activities and well-being among subjects with prostatic hypertrophic symptoms and the general population. Method: One hundred subjects with prostatic hypertrophic symptoms and one hundred general persons were recruited in K medical center. The data were collected from October 20, 2001 to March 30, 2002 by structured questionnaire. Result: The results were the following; 1. The percentage of mild(0~7), moderate(8~19) and severe(20~35) symptoms between subjects with prostatic hypertrophic symptoms and general persons were 6% : 60%, 54% : 39%, 40% : 1%. 2. There was a significant difference in prostatic hypertrophic symptoms(t=12.82, p<.001), in activities of daily living(t=-7.77, p<.0001), in satisfaction of sexual activities (t=-4.80, p<.0001), in well-being(t=-4.80, p<.0001) between subjects with prostatic hypertrophic symptoms and general persons 3. There was a significant difference in activities of daily living(F=16.28, p<.0001), satisfaction of sexual activities(F=3.98, p<.05) according to prostatic hypertrophic symptoms in subjects with prostatic hypertrophic symptoms. Conclusion : According to the above findings, prostatic hypertrophic symptoms influence activities of daily living, satisfaction of sexual activities, well-being of subjects with prostatic hypertrophic symptoms negatively.

제4경추의 형태와 초경을 통한 성숙지표에 관한 연구

이규홍,황용인,김윤지,박양호,백승학,차경석 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.1

본 연구는 측모 두부 규격 방사선사진을 이용하여 성장 중인 아동의 제4경추 형태를 경추 몸체부 하연의 만곡 정도에 따라 분류하고 초경의 시기와 수완부 골 성숙 단계를 평가하여, 성장 중인 아동의 골격적 부정교합의 진단 및 악정형 치료를 위한 성장 시기 평가에 제4경추의 형태 변화가 진단의 참고자료로 활용될 수 있는지를 연구하였다. 11-14세 여자 환자 중, 같은 날짜에 촬영된 측모 두부 규격 방사선사진과 수완부 방사선사진이 모두 있는 81명을 대상으로 환자의 측모 두부 규격 방사선사진상 제4경추 몸체부 하연의 만곡 정도에 따라 세 그룹으로 분류하였다. (Group A - 제4경추 몸체부 하연의 만곡 정도가 1.05 mm 이하, Group B -제4경추 몸체부 하연의 만곡 정도가 1.05- 2.07 mm 사이, Group C -제4경추 몸체부 하연의 만곡 정도가 2.07 mm 이상)세 그룹에서 각각 제4경추 몸체부의 수직 길이, 수평 길이, 수직/수평 비율, 초경의 시기, 수완부 골 성숙 단계를 측정한 결과 다음과 같은 결론을 얻었다. 평균 수완부 골 성숙 단계는 Group A가 SMI 5.67 ± 2.57단계, Group B는 SMI 8,73 ± 2.41 단계, Group C는 SMI 10.00 ± 1.47단계로 나타났다. GroupA에서 Group B, Group C로 갈수록 제4경추의 수직 길이, 수평 길이, 수직/수평 비율, 수완부 골 성숙 단계에 있어서 각각 유의하게 더 큰 값을 보였다. 본 연구대상 아동의 평균 초경 시기는 11.64 ± 0.92세를 보였다. 제4경추 몸체부 하연의 만곡 정도, 수직 길이, 수평 길이, 수직/수평 비율은 수완부 골 성숙 단계와 각각 서로 유의한 양의 상관관계를 나타냈다. 초경을 경험한 그룹이 초경을 경험하지 않은 그룹에 비해 제4경추의 수직 길이, 수평 길이, 수직/수평 비율, 수완부 골 성숙 단계에 있어서 유의하게 큰 값을 보였다. 연구 결과 측모 두부 규격 방사선사진상 제4경추 하연의 만곡 깊이가 2.07 mm 이상인 경우 성장의 완료 단계에 가까운 시기로 나타나 이 시기의 악정형적 치료는 큰 효과를 얻을 수 없을 것으로 사료된다. Objective: This study analyzed the morphologic changes of the fourth cervical vertebra body to determine the skeletal age of orthodontic patients during growth. Methods: Eighty-one female patients aged from 11 to 14 who had cephalograms taken on the same day were examined. The subjects were divided into three groups depending on the depth of the concavity of the lower border of the fourth cervical vertebra (Group A: less than 1.05 mm, Group B: 1.05 - 2.07 mm, Group C: greater than 2.07 mm). Menarcheal timing, SMI stage, length, width and ratio of length and width of the fourth cervical vertebra body were analyzed and the following results were obtained. Results: The average SMI stage of group A,B and C were 5.67 ± 2.57, 8.73 ± 2.41, and 10.00 ± 1.47, respectively. Length, width, ratio of length and width, and SMI stage were greater in group B than group A and in group C than group B. Mean menarcheal timing was 11.64 ± 0.92 years. Concavity depth, length, width, ratio of length and width showed a significant positive correlation with SMI stage, especially with the concavity depth. Conclusion: The results of this study propose a simple method for determining the timing of orthopedic treatment by measuring the concavity depth of the fourth cervical vertebra on the cephalogram.

병원행정직직원의 보수만족에 영향을 미치는 요인

이영석,류구수 慶山大學校 保健福祉硏究所 1999 保健福祉硏究 Vol.2 No.-

After national insurance system is launched, the number of hospital managing staffs have been increased to cover the new demands. To justify their labor costs, hospitals need efficient control in wage level of their empolyees, especially in administrative personnel. This study aims to figure out factors associated with the degree of wage satisfaction of administrative personnel in hospitals. I survey 260 administrative personnel in 5 general hospitals for the study. The results are as follows. First, high level of wage is not always related with their satisfaction of wage level. The level of satisfaction is affected by demographics such as age, sex, education level, and etc... Second, the wage level of administrative personnel is higher than other industry. However, college graduates in hospitals receives less salary than other industry's. Therefore, hospitals should raise wage level for their college graduates employees. Finally, the service years of employees is highly related with the level of wage satisfaction. As working years goes by, the level of satisfactions reduced. Therefore, hospital managers should pay more salaries for employees who have been serving long period by developing payment system such as a longevity allowance.

TSC 합성보의 제작방법에 따른 구조적 거동에 관한 실험적 연구

이지운,김도훈,김성배,이창남,김상섭,김규석 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Composite action can be achieved by providing shear connectors between steel top flange and concrete topping. Composite sections have larger stiffness than the summation of the individual stiffness of slab and beam, therefore, can carry larger load or similar loads with appreciably smaller deflection and are less prone to transient vibration. T-type Steel Composite beam(TSC-beam) is developed and tested. To make the part of steel beam, we used the way of welding two steel plates as well as the way of folding one steel plate.

중학교 과학과 학습내용 구성의 문제점과 그 개선 연구

이규석,우종옥 한국교원대학교 과학교육연구소 1991 청람과학교육연구논총 Vol.1 No.1

현행 중학교 과학과 교육과정 중 교육 내용의 선정과 조직상의 문제점을 추출하여 그 개선점을 논의하였다. 교육 내용의 선정과 조직상의 문제점은 교육과정을 구성할 때에 교육 내용의 선정과 조직에 관하여 일반적으로 요구되는 원리를 준거로 하고 우리 나라가 해방 후 오늘에 이르기까지 5차에 걸쳐 교육과정을 구성함에 있어서 중점적으로 강조하였던 점을 고려하여 추출하였다. 추출된 문제점의 개선 방향은 주로 그간 발표되었던 문헌을 중심으로 조사 분석하고 현장 교사의 의견을 조사하여 이를 바탕으로 논의를 하였다. 그리고 그 결과를 기초로 교육과정 내용 선정과 조직에서 나타난 문제점의 개선 방안의 일부를 제언하였다. The problem of contemporary curriculum is extracted by rationale of curriculum and our last nation's curricula in the middie school. As the results, it is problems in goals and learning contents, level and quantity of contents, ratio of science region, constitution's ratio of activity and information, experiments, practical science, content of science history and science and society, uniformity of contents, integrated science. The problem is analysed to study of improvement plan for the selection and organization of contents of science in the middle school. Resulting of these analyses this study states to improve plan for curriculum of middle school in Korea.

플라즈마를 이용한 유리섬유강화 복합절연재료의 표면처리에 관한 연구

이규철,남창우,김희대,황영한,김경석 울산대학교 1997 공학연구논문집 Vol.28 No.1

본 연구에서는 에폭시계 복합 절연재료 Glass-cloth/Epoxy 의 계면 접착특성을 향상시키기 위하여 표면처리 조건에 따라 각각 복합 절연재료를 제작하였고, 전기·기계적특성의 상관관계를 다음과 같은 실험을 행하여 비교하였다. Glass의 젖음의 정도를 평가하기 위하여 표면처리 조건에 따라 주위온도 80[℃]에서 접촉각을 측정하였고, 주위온도 및 인가전압을 변화시키면서 비유전율(εr), 유전정접(tanδ) 및 전기적 절연강도를 측정하였다. 기계적 특성을 측정한 후에 파단면의 형상을 SEM으로 분석, 검토하였다. 실험 결과, (1) 주위온도가 상승함에 따라 비유전율 및 유전정접은 증가하였고, 전기적 절연강도는 감소하였으며 플라즈마 처리함으로서 전기·기계적특성은 전반적으로 향상되었다. (2) 접촉각 측정 주위온도가 80[℃]일 때, 표면처리 조건에 따른 젖음성은 각각 다르게 나타났고 플라즈마 처리효과는 표면세정, 미세요철, 표면대전 및 젖음성의 감소와 같은 복합효과로 볼 수 있다. (4) 전기·기계적특성의 관점에서 복합 절연재료의 경화온도가 80[℃]일 때, Glass-cloth/Epoxy복합 절연재료의 최적처리시간은 3분 정도로 나타났다. The Glass-cloth/Epoxy composite insulating materials for this study have been prepared with several different surface treatmenttechniquen such as untreatment ultrasonic treatment and plasma treatment, and their electrical and mechanical characteristics have been compared each other. It has been found that plasma-treated glass has the smallest contact angle with a drop of epoxy. The plasma-treated composite materials have superior dielectric strength and mechanical tensile-strength compared to the materials subjected to other surface treatments. Also, the experiment showed that there exists an optimum plasma treatment duration for improving the interfacial characteristics of the composite insulating materials. The optimum plasma treatment durations are about 3 minutes for Glass-cloth/Epoxy at 80[℃]. Longer plasma treatment has been appeared to degrade the interfacial characteristics.