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      • FCT 5 : Fractional laser-assisted topical imiquimod 5% cream treatment for recalcitrant common warts in children

        ( Hyun Chang Ko ),( Jeong Min Kim ),( Hyun Ho Cho1 ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

        Background: Conventional destructive modalities for warts like cryotherapy or laser ablation have some limitations that are excruciating pain during procedure, in especially pediatric patients. Imiquimod is a topical immune response modifier that was approved for treating genital and perianal warts. But, thick stratum corneum of common warts may act as a barrier against drug permeation via the skin. Objectives: To evaluate efficacy and safety of above treatment. Methods: Eleven pediatric patients (6 female and 5 male, mean age 12.5 years) were included in this study. The lesions were treated by fractional 2940 nm Er:YAG laser for achieving the penetration of stratum corneum with 1 or 2 weeks intervals. Then, imiquimod 5% cream was self-applied once daily for 5 days a week. Assessment of response and adverse effects was performed every 2 weeks until complete clearance or up to maximum of 48 weeks. Pain during procedure was checked by VAS (0-10). Results: 8 out of 11 (72.7%) patients experienced complete clearance of all warts lesions. Mean duration of total treatment was 29.7 (16-48) weeks. Mean number of fractional laser treatment was 17.5 (8-37) times. No significant adverse effect was observed. VAS score of the pain during fractional laser treatment was 2.4 (1-4), comparing with 6.2 (5-8) during cryotherapy. Conclusion: Fractional ErYAG laser-assisted topical 5% imiquimod cream is an effective and safe treatment option for recalcitrant common warts of the children do not tolerate pain well.

      • Information Technology의 기존 관광산업에 대한 영향 및 향후 Trend에 대한 전망 : 사이버여행사 수익모델을 중심으로 Profit Model of Cyber Travel Agency

        조현준,나윤중,임형순,엄서호 한국문화관광학회 2001 문화관광연구 Vol.3 No.1

        IT has an influence on the travel agency as chance and threat. The purpose of this study is to find what profit model of cyber travel agency. Ernst&Young's five business profit models that are based on target audience and transaction focus is selected to evaluated existing model of cyber travel agency. Those are off-line facilitator, gateway, context provider, commerce destination, online exchange. The result of this study show that there is no specific profit model in domestic cyber and on-offline travel agencies. Just Portal cyber travel agencies abroad have a few profit model. They have online exchange model, which are various target audience and abound provide contents.

      • KCI등재후보

        상악 제1대구치 근심협측 치근의 근관계에 관한 연구

        조동현,최호영,박상혁,최기운 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.3

        This study is to investigate the canal system in the mesiobuccal root of the maxillry first molar. 61 maxillary first molars were randomly selected. Serial transverse sections were made perpendicular to the long axis of the mesiobuccal root. Each section was placed in 3% sodium hypochlorite for 24 hours and rinsed in water and dried. The resected surface was stained with 2% methylene blue dye and examined with stereomicroscope. 1. Canal configuration analysis showed that 36.1% of the specimen classified as type Ⅰ, 16.4% as type Ⅱ, 37.7% as type Ⅲ and 9.8% as type Ⅳ. 2. Type Ⅱ canal was merged in one canal within 1 to 4mm of the apex. 40% of type Ⅱ cnal coverged at 2mm of the apex. 3. Type Ⅳ canal was divided into two canal within 2 to 4mm of the apex. 66.6% of type Ⅳ canal branched off at 2mm of the apex. 4. None of the sections had more than two main root canal. 5. 48.4% of the sections in 3mm with two canals contained an isthmusand more than 70% with two canals has isthmus at 4 to 5mm sections. 63.9% of the mesiobuccal root of maxillary first molar had two canaland 76.% of sections with two canals in 5MM had an isthmus. Because of this complexity the clinician should always search for extra canal carefullyand root canal system, including an isthmus, should be cleaned and shaped completelyand obturated three dimensionally for successful endodontic treatment.

      • Helicobacter pylori와 대장균의 Shuttle Vector 개발

        조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

        In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

      • 참나무 群落地의 植物群集構造分析 : Ⅰ. 白雲山의 植物群集構造分析 Ⅰ. Plant Distribution and vegetation structure in Mt. Bakwoon

        趙顯瑞,李喆浩 진주산업대학교 1998 論文集 Vol.37 No.-

        백운산 내회지역과 지리산 대원계곡의 삼림군집구조를 파악하여 우량종 육성에 필요한 자료를 분석한 결과는 다음과 같다. 1. 백운산지역 95개 조사지를 TWINSPAN에 의하여 classification을 분석한 결과, 남사면에서는 양수인 소나무 군집으로 구분되었으며, 북사면에서는 활엽수흔효군집으로 구분되었다. 2. 백운산지역 조사지는 DCA에 의하여 1, 2축에 우측에서 좌측으로 소나무군집, 굴참무군집, 졸참나무-굴참나무군집, 졸참나무군집, 서어나무군집으로 분리되었고, 상, 하로 신갈나무군집, 활엽수흔효군집, 고로쇠나무군집 등의 8개 군집으로 분리되어 TWINSPAN보다 DCA방법이 효과적이었다. 3. 백운산 지역 군집간의 유사도지수를 분석한 결과, 소나군집과 졸참나무군집, 소나무군집과 서어나무군집, 소나무군집과 고로쇠나무군집, 신갈나무군집과 고로쇠나무군집의 유사도지수가 20%미만을 나타내어 이질적인 군집임을 알 수 있었고, 졸참나무-굴참나무군집과 굴참나무군집, 졸참나무군집, 활엽수흔효군집 그리고 굴참나무군집과 활엽수흔효군집간에는 55% 이상의 높은 값을 나타내었다. 4. 백운산지역 토양 환경인자의 DCA분석에서 토양산도를 제외하고 모든 인자의 A군집(소나무군집)에서 E군집(서어나무군집)으로 갈수록 증가하는 경향이었다. 5. 백운산지역 토양산도, 수분함량, 유기물함량 및 K^+, Ca^++, Mg^++ 등 토양환경요인을 DCA기법을 적용한 결과, 대부분의 요인에서 소나무, 신갈나무군집은 낮은 계급을 나타내었고, 서어나무군집, 활엽수흔효군집, 고로쇠나무군집 등에서는 높은 계급에 위치하고 있었다. This paper aims at analyzing the plant community in Mt. Bakwoon area. The plant community in Mt. Bakwoon was divided into 95 plots by clumped sampling method. According to DCA ordination, Mt. Bakwoon is composed of Pinus densiflora, Quercus variabilis, and Q. serrata communities. The similarity index between Quercus variabilis and mixed stands of broad leaved trees was more than 55%.

      • 세침 흡인술을 이용한 종창된 림프절의 세포학적 평가

        백강현,윤기영,최호정,정성목,이영원,조성환,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

        Fine needle aspiration(FNA) cytology is considered as the diagnostic technique of choice in the assessment of swellen lymph nodes. The aim of this study is to determine the indication and diagnostic method of FNA of lymph node lesions performed at Veterinary Medicine Teaching Hospital of Chungnam National University. The records of 16 patients which had undergone FNA during the study period were retrieved. The cytological results were classified as lymphadenitis, lymphoid hyperplasia and lymphoma. Lymphoma cases were classified as B-cell origin and T-cell by immunophenotyping. The result of the FNA cytological diagnosis showed that nine (56%) of the patients were lymphoma, five (31%) of the patients were lymphoid hyperplasia and two (13%) of the patients were lymphadenitis.

      • 개 전염성 기관기관지염 치료 증례

        조현석,김대희,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

        A 8-year-old male castrated yorkshire terrier dog with a infectious tracheobronchitis was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Infectious tracheobronchitis was diagnosed by the history, clinical signs, polymerase chain reaction, laboratory examinations (complete blood count, serum chemistry) and the diagnostic imaging. The clinical signs were improved after antibiotics treatment. Doxycycline is effective for Bordetella bronchiseptica as infectious tracheobonchitis in a dog.

      • 연쇄상구균을 실험감염시킨 넙치치어의 병리조직학적 관찰

        조성환,류시윤,김현수,박배근,김덕환,손화영,윤원기,신창호 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-

        Pathological observations were examined after abdominal inoculation in 7∼8㎝ sized flounder (Paralichthys olivaceus) with 1X10^7 cfu/㎖ of Streptococcus faecalis. The infected flounder were clinically observed and weighed a fish body at 0, 5, 10, 15, 20, 25, 30 days post inoculation. In infected group, mortality were 70% and feed efficiency were 7.2%. In non-infected group, mortality were 10% and feed efficiency were 18.2%. Macroscopically, the significant lesions were characterized by protrusions and opacity of the eyes and ulcer of the caudal pecuncle. Histopathologically, the lesions were observed a degeneration. necrosis and inflammatory cells in muscle of the caudal peduncle and a degeneration and necrosis of the rod cells and detached retina from the black pigmented layer

      • KCI등재

        이중에너지 방사선 흡수계측법을 이용한 성인 남녀의 장골 및 경골의 골밀도에 관한 연구

        조용석,김경원,이경호,박현진,서상수,오상엽 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.3

        Purpose : The aim of this study was to evaluate the bone mineral density of iliac and tibial bone which are frequently selected as autogenic bone graft donor sites, and to evaluate the efficiency of this method as a guideline for the selection of bone graft donor site. Materials and Methods : In this study 61 male and 70 female volunteers at Chungbuk National University Hospital were involved between Jan. 1998 to Sept. 1999. We measured bone mineral density of the iliac and the tibial bone using dual energy X-ray absorptiometry. We evaluated the data using the SAS system for Windows and bone mineral density of the lumbar was used for control. Results : Age showed the highest correlation in correlation matrix between physical and bone variables. Height and weight showed lower correlation of linear increment. In man, the change of bone density according to age demonstrated linear decrease irrespective of the lumbar, ilium, and tibia. In woman, the change of bone density according to age showed cubic form, which increased in the third and forth decade. So it had a peak bone mass on about 35 year-old, thereafter, the change of bone density slowly decreased until 50 year-old, but it rapidly decreased after 50 year-old and it slowly decreased again after 65 year-old. Both in all subjects and subject with osteoporosis, the change of bone mineral density according to age showed statistically significant decrease in lumbar and tibia, but ilium was irrespective. Conclusion : In patients of aged or with osteoporosis, ilium demonstrated less tendency of decrease in bone mineral density than tibla. So this preliminary study suggested that ilium seemed better donor site for autogenic bone graft than tibia.

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