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증례 : 내분비-대사 ; 부신수질증식증이 동반된 알도스테론 분비 부신피질선종 1예
이향선 ( Hyang Sun Lee ),김건우 ( Gun Woo Kim ),김재현 ( Jae Hyun Kim ),이미영 ( Mi Young Lee ),엄민섭 ( Min Sub Eum ),신영구 ( Young Goo Shin ),정춘희 ( Choon Hee Chung ) 대한내과학회 2011 대한내과학회지 Vol.81 No.3
부신피질과 수질은 서로 다른 기원과 기능을 가지고 있으나 드물게 혼합된 임상소견을 보이는 경우가 보고되고 있다. 저자 등은 갈색세포종의 증상을 보여 시행한 호르몬 검사상 알도스테론 분비 부신피질선종의 소견을 보인 환자에서 수술 후 병리 조직 소견상 부신피질선종과 부신수질증식증이 동반된 드문 경우가 있어 문헌고찰과 함께 국내에서 처음으로 보고하는 바이다. The relationship between the adrenal cortex and medulla has been studied since the 1960s. Rarely, a patient with an adrenal cortical adenoma presents with the findings of pheochromocytoma. However, there has been no report of a case with the clinical features of pheochromocytoma showing the pathological features of an adrenal cortical adenoma with medullary hyperplasia on histological examination. We report a 59-year-old-man who was shown to have an adrenal cortical adenoma, with medullary hyperplasia, during a diagnostic work up for pheochromocytoma. (Korean J Med 2011;81:393-396)
만성 B 형 간염환자에서 인터페론 치료 중 발생한 급성 신부전 1 예
김종철,박경남,한동수,이민호,강경원,최호순,윤병철,이동후,손주현,이오영,함준수,이원미,박문향,전용철,기춘석 대한내과학회 2001 대한내과학회지 Vol.61 No.1
Hepatitis B virus infection is known to be associated with various types of glomerulonephritis (GN), including membranous GN, membranoproliferative GN, and mesangial proliferative GN. Although there has been considerable experiences with interferon in clinical trials during the past decade, acute renal failure as a complication of interferon treatment has rarely been reported. We report a case in which acute renal failure with proteinuria was associated with interferon-alpha treatment. A 33-year-old man with chronic hepatitis B presented with diarrhea and RUQ pain. Two weeks after INF-alpha treatment, Oliguria and proteinuria suddenly occurred, although the hepatic function was improved. With discontinuation of interferon treatment and ultrafiltration, his renal function was improved. (Korean J Med 61:59-63, 2001)
Hyang-Mi Park,김율호,Man-Soo Choi,Do-Yeon Kwak,Bong-Choon Lee,Jong-Hee Lee,Myeong-Ki Kim,Yeon-Gyu Kim,Dong-Bum Shin,박순기 한국분자세포생물학회 2012 Molecules and cells Vol.33 No.1
Rice stripe virus (RSV) is a viral disease that seriously impacts rice production in East Asia, most notably in Korea, China, and Japan. Highly RSV-resistant transgenic japonica rice plants were generated using a dsRNAi con-struct designed to silence the entire sequence region of the RSV-CP gene. Transgenic rice plants were inoculated with a population of viruliferous insects, small brown plan-thoppers (SBPH), and their resistance was evaluated using ELISA and an infection rate assay. A correlation between the expression of the RSV-CP homologous small RNAs and the RSV resistance of the transgenic rice lines was discovered. These plants were also analyzed by comparing the expression pattern of invading viral genes, small RNA production and the stable transmission of the RSV resistance trait to the T3 generation. Furthermore, the agronomic trait was stably transmitted to the T4 generation of transgenic plants.
Cadmium과 Sulphur 증기 분위기에서 열처리된 CdS 단결정의 열자국 발광
이춘호,김영기,전경남,박향숙 全北大學校 基礎科學硏究所 1991 基礎科學 Vol.14 No.1
Cadmium과 sulphur 중기 중에서 열처리한 CdS 단결정에 대한 열자극 발광을 액체질소 온도로부터 400K 까지의 범위에서 측정하여 열자극 발광(TSL) 글로우곡선을 얻었다. 글로우곡선은 thermal cleaning법과 시료의 온도를 내리면서 자외선을 조사할 때 조사가 끝나는 점의 온도를 차차로 높여 가면서 여러번 글로우곡선을 측정하는 방법을 써서 분석하였다. 분해된 봉우리점의 온도는 110, 160, 195, 235, 260, 295, 330 그리고 365K 이었다. 이들 봉우리를 나타내는 trap의 활성화에너지와 진동수인자의 값을 여러 가지 방법으로 구하였고, Bube^[2]와 Woods^[3]등이 다른 방법으로 얻은 값과 비교하였다. 195K와 295K의 TSL 봉우리는 각각 S와 Cd 중기 분위기하에서 열처리된 결정에서 감도가 크게 나타났으며 365K 봉우리는 Cd 증기 분위기하에서 열처리한 결정에서만 관측되었다. 따라서 195K 봉우리는 고립된 Cd 빈자리와 관련되는 봉우리이고 295K 봉우리는 S 빈자리에 기인하는 봉우리이명 365K 봉우리는 방사선이 조사되는 과정에서 coloid 모양의 Cd 집합체가 생기고 집합체가 천이되는 과정에서 생기는 발광 봉우리라고 생각된다. The glow curves of thermally stimulated luminescence were measured on the CdS single cyrstals annealed in cadmium and sulphur vapours in the range of temperature from liquid nitrogen to 400K. In order to analize the glow curves, we used the methods of thermal cleaning and the temperature of irradiation point was gradually increased. Using this method, we observed eight glow curves of the peak at 110, 160, 195, 235, 260, 295, 330 and 365K. The activation energies and capture cross sections for each of those peaks were calulated using a number of different analytical methods and compared with other data. The 195K and 295K peaks are the dominant feature observed in crystals annealed in sulphur and cadmium vapours respectively, but the 365k peak are found only in cadmium-rich crystals. The 195K and 295K peaks are associated with isolated cadmium vacancies and sulphur vacancies respectively. We infer that the 365K peak is due to the process of transition of colloidal aggregation of cadmium, since colloidal aggregation of cadmium appears during the exposure of sample to the radiation.
기관지 협착증이 동반된 어려운 기관내 삽관(Difficult intubation) 환아의 마취관리 1례
백향원,김치효,김종학,이춘희 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.3
The infant or child with a difficult airway is easily recognized, either by symptomatology or anatomic features. However, in a small but significant number of cases, a difficult airway is unrecognized during the preanesthetic assessment, and becomes recognized only upon the induction of anesthesia. We report a case of difficult airway with congenital tracheal stenosis in neonate. We performed tracheal intubation with small sized tube by using technique to bring head forward slightly while trying to advance tube.
학교폭력예방 및 대책에 관한 법률에서의 학교폭력예방교육의 문제점과 개선방안
정향기 ( Jung Hyang Gi ),이학춘 ( Lee Hak Choon ) 한국사회복지경영학회 2017 사회복지경영연구 Vol.4 No.2
본 논문의 연구목적은 학교폭력예방 및 대책에 관한 법률에서 밝히고 있는 것처럼 입법취지에서 벗어난 예방교육의 문제점이 무엇인지를 찾아보고 그 개선방안을 마련하는데 있다. 구체적으로는 예방교육의 내용상의 문제점과 시행과정에서 그 내용의 불분명성과 해석상의 논란이 될 수 있는 문제와 타당성에 의문이 있는 것들에 대하여 논의와 검토과정을 거쳐 개선방안을 마련하는데 있다. 그동안 정부와 시민단체, 지역사회와 학교에서 학교폭력예방을 위한 다양한 노력에도 불구하고 학교폭력예방 및 대책에 관한 법률 제정과 함께 그 법률의 시행과정에서 교육적 관점, 피해자와 가해자에 대한 조치, 학교폭력의 특수성 등을 고려한 예방과 대책이 좋은 평가를 얻지 못하고 있다. 학교폭력예방교육의 실제를 검토해 본 결과, 첫째, 학교폭력예방 및 법률의 입법취지에 입각한 예방교육의 문제점과 책무성이 강화될 필요성이 있다. 둘째, 청소년 범죄예방을 위한 청소년관련법의 보완과 개정이 요구되고 있다. 셋째, 청소년의 윤리의식을 강화할 필요성이 있다. 넷째, 학교에 설치된 자치위원회는 학교폭력예방과 대책방안을 위하여 전문성과 공정성, 사법적인 권위에 따른 그 실효성을 강화할 필요가 있다. 현실적으로 자치위원회는 예방과 예방을 위한 조치만을 다루고 실제 발생된 학교폭력사건에 대한 처리는 자치위원회가 아닌 시군구 지역단위에 설치된 위원회에서 담당하도록 하는 것이 바람직하다. The purpose of this study is to find out the problems of preventive education which is out of the legislative intent and to prepare the improvement plans, as clarified in the Act on prevention and countermeasures for school violence. Specifically, it is to prepare the improvement plans through discussions and review process about subjects such as problem in content of preventive education, ambiguity of the content in process on enforcement, problem that may be controversial in interpretation, and things are doubtful about validity. Despite various efforts for prevention on school violence between government, civic organizations, local communities, and schools in the meantime, they are not well evaluated even in the enactment of the Act on prevention and countermeasures for school violence and prevention and countermeasures that take account of educational perspectives, measures toward victims and offenders, and specificity of school violence in process of enforcement. As a result of examining the reality of preventive education for school violence, first, it is necessary to strengthen the problems and accountability of preventive education based on the school violence prevention and the legislative intent of the Act. Second, the supplementation and reform of juvenile laws have been required to prevent juvenile delinquency. Third, there is a need to reinforce ethics of adolescents. Fourth, the self-governing committees established in the schools need to strengthen the effectiveness according to professionalism, fairness, and judicial authority for school violence prevention and its countermeasure plans. In reality, it is desirable that the self-governing committees deal only with prevention and measures for prevention, and the actual incidents of school violence should be handled by the committees established at local and regional level.
NIgA 신병증을 동반한 자가면역성 간염과 원발성 담관성 간경변증의 Overlap Syndrome 1 예
한동수,이명호,장세진,조균석,기춘석,전용철,박문향,김호중,노우균,손주현 대한소화기학회 1999 대한소화기학회지 Vol.32 No.6
The case in which patients present clinical, biological, and histological features of both primary biliary cirrhosis (PBC) and autoimmune hepatitis (AIH) is rare. Such overlap syndrome is believed to be associated with a poor prognosis. We report a case of PBC-AIH overlap syndrome associated with IgA nephropathy. The patient showed hepatitic and nephritic features including easy fatigability, pruritus, icteric sclera and gross hematuria. The liver biopsy showed chronic hepatitis with piecemea necrosis and bridging necrosis. The clinical data of high titers of antinuclear antibodies and antimi tochondrial antibodies, elevated serum IgM and recurrent pruritus, suggest mixed features of AIH and PBC. IgA nephropathy was confirmed by renal biopsy. High dose of corticosteroids was effective initially, but clinical symptoms were relapsed after tapering the administration of corticosteroids. Thus, azathioprine was administered at a dose of 2 mg/kg/day. A dramatic improvement was noted in clinical conditions and liver tests.