Pathological characterization of TgElk mice injected with brain homogenate from elk with chronic wasting disease

전용철,최진규,최은경,Richard I. Carp,김용선 대한수의학회 2013 Journal of Veterinary Science Vol.14 No.1

Chronic wasting disease (CWD) is classified as a transmissible spongiform encephalopathy or prion disease that affects cervids. CWD has been reported in 15 US states,two Canadian provinces, and in imported elk on several farms in Korea. This study was conducted to examine the molecular biological and pathogenic characteristics of a CWD-associated prion isolated in Korea. The epidemiological origin of this pathogen was also determined. Homozygous TgElk mice were infected with a CWD-affected elk brain pool prepared from the brain of an imported Canadian elk. We measured the incubation time of the pathogen, neuropathological changes by immunohistochemical staining, the pattern(s) of scrapie prion protein (PrPSc) deposition, and PrPSc protein profiles by Western blotting. We found that TgElk mice infected with brain homogenate from the elk suffering from CWD showed incubation times, vacuolar degeneration, and PrPSc accumulation similar to those previously reported in the literature. Our results suggest that homozygous TgElk mice efficiently transmit CWD with short incubation times and that this animal can serve a valuable research model and reliable in vivo diagnostic tool.

스마트기기에 탑재 가능한 애플리케이션 관련 발명의 특허권법상 보호 방안에 관한 연구

전용철 민사법의 이론과 실무학회 2012 民事法理論과 實務 Vol.16 No.1

This paper discusses a scheme for protecting inventions, distributed in the form of applications that can be installed on smart devices (hereinafter referred to as “app-related inventions”), based on intellectual property laws and the protection limits of the current copyright law and patent law. App-related inventions can be treated in the same manner as software-related inventions in the current patent law, and can be granted patents if they fulfill predetermined requirements. However, since in the case of app-related inventions, the developer of an application and the manufacturer of a smart device are not normally subject to a subordinate-superior or supervisory relationship and independently perform their respective practices without any economic connection therebetween, a problem arises in that the app-related inventions cannot be substantially protected by the current laws even when they have been patented. That is, in the case of an app-related invention in which one or more software elements are combined with one or more hardware elements, a contradiction may occur in that the practice of a patented invention by a single agent is recognized as an infringement but the practice of the patented invention by a plurality of agents is not recognized as an infringement. This paper discusses a scheme for mitigating the all elements rule and using the mitigated rule and a scheme for introducing the provisions of induced infringement and contributory infringement to the patent law and calling upon the developer of software or an application to take responsibility for infringement in order to substantially protect app-related inventions that are practiced by a plurality of agents.

주왕산국립공원의 자생버섯 분포상

전용철,홍기성,최석영,김태헌,고평열 한국버섯학회 2018 한국버섯학회지 Vol.16 No.2

Mushrooms growing spontaneously in the Juwangsan National Park were surveyed from April to October 2017 for supporting management of higher fungi and creating a bio-diversity database of the park. In total, two divisions, eight classes, 21 orders, 85 families, 225 genera, and 503 species were detected. Among them, 247 species belonged to order Agaricales, which occupied 48.8% of the population, followed by members of orders Polyporales and Russulales. The mushrooms were abundant in August, and an altitude of 300-400 m above sea level was optimal for their growth, such as those found at Sanguijigu, Deajeonsa, and Geodaeri semgoal areas. Furthermore, Macrolepiota procera and Sarcodon aspratus, which belong to criteria of climate change, were detected in this survey.

[내 머릿속 두 글자] 단풍

전용철 새가정사 2017 새가정 Vol.703 No.-

쇼트 비디오 플랫폼의 부정적인 정보요인 관점에서 살펴본 소셜미디어 이용중단의도: 중국 틱톡(Tik Tok)이용자를 중심으로

전용철 한국콘텐츠학회 2024 한국콘텐츠학회논문지 Vol.24 No.5

쇼트 비디오 플랫폼은 이용자에게 표현의 자유, 재미를 비롯한 '밝은 면'을 제공하는 반면, 많은 부정적인 정보 요소들이 '어두운 면'을 구성하여 이용자의 지속적인 플랫폼 이용의도를 제약한다. 본 연구는 자극-유기체-반응(SOR) 모델을 프레임워크로 삼아 쇼트 비디오 플랫폼의 '어두운 면'이 이용자의 플랫폼 이용중단의도에 어떤 영향을 미치는지 살펴본다. 본 연구 결과에 따르면 콘텐츠 저속화 외에도 광고 방해성, 정보 모호성, 루머의 확산이 이용자 플로우 경험의 형성을 지연시키고, 이 네 가지 부정적인 정보 요인이 쇼트 비디오 이용자의 소셜 미디어 피로감을 유발하여 소셜 미디어 이용중단의도로 이어진다는 사실을 발견했다. 동시에, 플로우 경험은 이용중단의도에 대한 세 가지 완화효과가 있다. 첫째, 소셜 미디어 피로감이 이용중단의도에 미치는 영향을 완화하고, 둘째, 소셜 미디어 피로감의 형성을 방해하며, 셋째, 이용자의 이용중단의도를 직접적으로 감소시킨다. Short video platforms provide users with a "light side" that includes freedom of expression and fun, but a lot of negative information elements constitute a "dark side" that limits users' intention to continue using the platform. This study adopts the Stimulus-Organism-Response (SOR) model as a framework for exploring how the "dark side" of short-video platforms influences users' intention to discontinue using the platforms. Our results show that in addition to content vulgarization, advertising interference, information equivocality, and rumor dissemination delay the formation of user flow experience, and these four negative information factors cause social media fatigue in short video users, leading to social media discontinuing intention. At the same time, the flow experience has three moderating effects on discontinuing intention. First, it moderates the effect of social media fatigue on discontinuing intention, second, it hinders the formation of social media fatigue, and third, it directly reduces users' discontinuing intention.

Synthesis and Characterization of Poly ( Siloxane - Urethane )

전용철,강석호,임진수,신재섭,김공수 한국고분자학회 1991 한국고분자학회 학술대회 연구논문 초록집 Vol.1991 No.10

[내 머릿속 두 글자] 감사

전용철 새가정사 2017 새가정 Vol.704 No.-

Treatment of an Adult Patient with Atopic Dermatitis Using Traditional Korean Medicine, Especially Sa-Am Acupuncture

전용철,이현배 사단법인약침학회 2016 Journal of Acupuncture & Meridian Studies Vol.9 No.6

Atopic dermatitis is known not to respond well to many clinical treatments. In this report, we present the case of an adult woman with atopic dermatitis who was effectively treated by using traditional Korean medicine (TKM). The patient was diagnosed with psoriasis based on lung dryness and heat and heart fire. The patient underwent acupuncture treatment based on the theory of Sa-Am acupuncture. Two meridians, the hand tai-yin meridian and the foot tai-yang meridian, were used to control lung dryness, lung heat, and heart fire. Using the LU9 and SP3 acupoints to tonify the hand tai-yin meridian, we could sedate lung dryness and heat, and using the BL67 acupoint to tonify the foot tai-yang bladder meridian, we could sedate heart fire. With this treatment, her symptoms completely disappeared in about 6 months. This case report provides a preliminary indication that TKM, especially Sa-Am acupuncture, can be effective for treating patients with psoriasis. Thus, further study is warranted.

[가정 뉴스 되새김] 삶과 죽음 그리고 종교

전용철 새가정사 2018 새가정 Vol.712 No.-

[이슈, 오늘] 선택적 정의 NO! 거짓말은 하지 맙시다!

전용철 새가정사 2020 새가정 Vol.738 No.-