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이중구조 촉매전극을 이용한 알칼리 연료전지에 관한 연구
노용우,이태희,설용건,장의종,김경림 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.1
An experimental low-temperature low-pressure hydrogen-oxygen alkali fuel cell was constructed and its performance was tested for various operating conditions. Hydrogen was used for fuel and oxygen was used for oxidant and KOH solution was used for electrolyte. Both electrodes for hydrogen and oxygen were prepared by the same method and the materials used were carbonyl nickel and ammonium bicarbonate. Experimental results show that maximum current density of 8.91 mA/㎠ was obtained at 40℃ wt% KOH solution and optimum power was 1.74 mW/㎠ at 6.43 mA/㎠ current density.
산화구리에 의한 배기 가스 중의 아황산 가스 제거 : 반응속도에 관한 연구 A Kinetic Study
신창섭,노용우,이태희 연세대학교 산업기술연구소 1985 논문집 Vol.17 No.2
The reaction of cupric oxide powder with 2% sulfur dioxide was investigated over a temperature range of 300-500℃ and over a particle size range of 0.051-3㎜. The experimental data were correlated well by the shrinking unreacted core model and the optimal reaction temperature was found to be 450℃. With average particle diameter less than 1㎜ and superficial gas velocity higher than 8.8 ㎝/sec, the reaction of cupric oxide powder with sulfur dioxide was found to be controlled by the chemical reaction and the intrinsic rate constant was k=8987 exp(-8134/RT).
김성엽,설용건,이태희,노용우 연세대학교 산업기술연구소 1991 논문집 Vol.23 No.2
Pore structure and acid absorbancy of carbon electrode of phosphoric acid fuel cell were studied by varying carbon black, PTFE loading, and fabricating method for Denka black. Results showed that the primary pore(micro pore) of the carbon electrode included the micro space formed around the carbon particles regardless of the carbon black(Vulcan XC-72 and Denka black) used, and that addition of PTFE and pressing of electrode influenced mainly the secondary proe. The acid absorbancy of electrode was decreased as PTFE loading was increased and Denka black showed more hydrophobic than Vulcan XC-72 with three times in saturation time and one-half in acid absorbancy.
천추 전방에서 발생한 신경절 세포종 : 증례 보고 A Case Report
강현구,이승로,박동우,박충기,함창곡,박용욱 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.2
We have experienced a case of presacral ganglioneuroma. So, we report a peripheral ganglioneuroma of sacral origin. The patient is 34-year-old man with intermittent low back pain and right sciatica. Myelographic computed tomography revealed extradural lobulated low attenuated tumor lesion within spinal canal at the level of L5 and S1. Tumor indented the thecal sac to the left side, and extended into the pelvic cavity through the intervertebral foramen between S1 and S2. The mass was surgically excised and turned out to be ganglioneuroma pathologically.
이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1
연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.
면역조직화학법을 이용한 점농어 ( Lateolabrax sp. ) 뇌에서 두 종류 ( sGnRH , CGnRH-2 ) 의 생식소자극호르몬 분비호르몬의 동정
김정우(Jung Woo Kim),이원교(Won Kyo Lee),양석우(Seok Woo Yang),정관식(Kwang Sik Jeong),조용철(Yong Chul Cho),노용길(Yong Gil Rho),방인철(In Chul Bang),김광수(Kwang Soo Kim),임상구(Sang Koo Lim),유명식(Myung Sik Yoo),권혁방(Hyuk Bang 한국수산과학회 1999 한국수산과학회지 Vol.32 No.3
Two forms of gonadotropin releasing hormone (GnRH) are identified in the brain of adult mature spotted sea bass (Lateolabrax sp.) by immunohistochemical methods. Salmon GnRH immunoreactive (sGnRH-ir) cell bodies were distributed in the olfactory bulb, ventral telencephalon and preoptic region. Immunereactive fibers were observed in the vicinity of the brain including the olfactory bulbs, the telencephalon, the optic nerve, the optic tectum, the cerebellum, the medulla oblongata and rostral spinal cord. In most cases, these fibers did not form well defined bundles. However, there was a clear continuum of immunoreactive fibers, extending from the olfactory bulbs to the pituitary. cGnRH-II-ir cell bodies were oily found in olfactory bulbs. However, the distribution of cGnRH-II-ir fibers was basically similar to that of sGnRH-ir fibers except for the absence of their continuity between the olfactory bulbs and the pituitary. These data suggest that sGnRH and cGnRH-II are endogenous peptides and indicate the presence of multiple neuroendocrine functions in the brain of the spotted sea bass. It seems that sGnRH not only regulates GTH secretion but also functions as a neurotransmitter, whereas cGnRH-II functions only as a neurotransmitter.
Ultrasonographic Evaluation of the Endometrial Maturation in the Clomiphene Induced Menstrual Cycles
Rho, Yung Sook,Lee, Jin Woo,Jung, Jae Keun,Lim, Yong Taik,Kim, Seung Jo CATHOLIC MEDICAL CENTER 1986 Bulletin of the Clinical Research Institute Vol.14 No.1
The thrity-two clomiphene induced menstrual cycles were ultrasonographically monitored in order to evaluate the ultrasonographic phasic changes of uterine endometrial morphology and thickness with the follicular maturation (Dates: March, 1985 to February, 1986). 1. The ultrasonographic endometrial changes The ultrasonographic endometrial changes in the early proliferative phase was characterized by a long thin endometrium which became much thicker, giving evidence of growth in endometrial glands and stroma. The stromal cells of the superficial layer may be separated by transduate which was ultrasonographically demonstrated by a hyporeflective area. Following ovulation, we observed the 'ring' sign as an indirect evidence of ovulation. 2. The endometrial thickness The thickness of the central midline uterine echogenic area was 7.29 ± 1.63 ㎜ (Mean ± S.E.M.) in the early proliferative phase. These were 11.43 ± 1.38 ㎜, 11.85 ± 1.08 ㎜, 12.06 ± 1.39 ㎜, 12.52 ± 1.53 ㎜, 13.21 ± 1.81 ㎜, and 13.58 ± 1.61 ㎜, from Day -5 to Day 0 (= The day of ultrasonographic follicular rupture), respectively. It were also 13.66±2.09 ㎜ in the early secretory phase and 15.38±2.31 ㎜ in the late secretory phase, respectively. 3. The mid-luteal serum progesterone level The mean serum level of the mid-luteal progesterone was 22.77±8.75 ng/ml. We concluded that ultrasonographic monitoring of the endometrial morphology and thickness accompanying ovarian follicle monitoring is helpful in determining the endometrial dating as well as the confirmation of the progestational effect on the endometrial tissue and in detecting other organic pelvic disease related to infertility and menstrual disorders.