췌장염에 의한 가성낭종내에 생긴 가성동맥류 : 1례 보고

오연희,이채경,김승현,이성우,양창현,이정호,이영현 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

만성 췌장염의 합병증으로 생긴 가성동맥류는 드문질환으로, 반복적으로 다량의 출혈을 일으킬 수 있으며, 치료를 하지 않을 경우 사망율이 높기 때문에, 조기 진단과 치료가 필수적이다. 저자들은 38세 남자 환자에서 췌장염의 합병증으로 생긴 가성낭종내에서 발생한 가성동맥류 1예를 경험하였기에 보고하는 바이다. 가성 동맥류의 색혈류도플러상 낭종내에 양방향 흐름의 와류를 볼 수 있었다. Pancreatic Pseudoaneurysm within Pseudocyst from Pancreatitis: 1 Case Department of Diagnostic Radiology and Internal Medicine, College of Medicine,DongGuk University Yeon Hee OH M.D., Chae Kyeong Lee M.D., Seoung Hyeon Kim M.D., Sung Woo Lee M.D., Chang Heon Yang M.D., Jung Ho Lee M.D., Young Hyun Lee M.D. Pseudoaneurysm from pancreatitis is uncommon, but it can cause recurrent and massive hemorrhage. Because of high morbidity and mortality, early detection and treatment of the pseudoaneurysm is needed. We report a case of pseudoaneurysm within pseudocyst from pancreatitis. Color-flow Doppler sonography shows bidirectional flow and turbulent arterial flow, within anechoic mass.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

카라기난 분해효소 생산균의 분리, 동정, 및 효소생산 최적 조건

양승택,주동식,박중제,이정석,김명식,이응호 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

해양 동식물, 토양 등으로부터 분리한 카라기난 분해능이 확인되었던 80여 균중에서 환원당 생성능이 가장 높았던 strain no.43 균주를 최종 시험균주로 선택하여 이 균주의 최적 효소 생산 조건을 실험하였다. 질소원으로는 nutrient broth 0.7% 농도가 가장 적절한 조건이었고, 탄소원의 농도는 카라기난 0.2%가 가장 높은 효소활성을 나타내었다. NaCl 농도는 1.5%, pH, 온도는 각각 7.0, 30℃로 이 조건에서 96시간 배양하는 것이 가장 적절한 효소 생산 조건이었음이 확인되었다. 각종 생화학 실험을 통해 동정을 행한 결과 그람음성 간균으로 oxidase, catalase 생성의 호기성균, indole 비생성, proline, arginine, serine, citrate, lactate 이용성, gelatin 액화, glucose, fructose, maltose 비이용, mannitol 이용 등의 특성으로부터 Pseudomonas alcaligenes로 동정할 수 있었고 Pseudomonas alcaligenes JCL-43으로 명명하였다. The 80 strains which produce carrageenan degrading enzyme were isolated from soils, mud, seaweed, marine moluscus and echonodermata samples. Among them, one isolated strain, which showed the highest activity to produced carrageenan degrading enzyme, was used for this study. The isolated strain was identified as Pseudomonas alcaligenes through its morphological, biochemical, and physiological characteristics. The best conditions for enzyme production were 0.7% nutrient broth and 0.2% carrageenan as nitrogen and carbon source, respectively. The optimal pH, NaCl, temperature and culture time for carrageenan degrading enzyme were 7.0, 1.5%, 30* and 96hrs, respectively.

卵穀에서 分離한 Klebsiella 屬菌의 抗生物質 耐性에 관한 硏究

梁成鎬,孫東和,鄭永健 대구산업정보대학 1987 논문집 Vol.1 No.-

This study was carry out to examine hygenic significance and antibiotic resistance of isolates of commercial egg shells. The results obtained from this study were as follows: (1) 266 strains of enteric bacteria were isolated from commercial egg shells. (2) 11 strains of Klebsiella Spp. were identified within 266 isolates. (3) MIC of antibiotics with cell wall synthetic inhibition capability showed wide range of difference which were 50-100 mcg/ml at penicillin 12.5-100mcg/ml at cephaloxyl. (4) Klebsiella Spp. were sensitive to tetracycline streptomycin with protein synthetic inhibition capability which are respectively 1.56-3.20mcg/ml 1.56-12.5mcg/ml and 8 strains within 11 strains of Klebsiella Spp. Were resistance to the lincomycin which overly showed 100mcg/ml.

國民學校 敎師의 指導性類形에 關한 硏究

양승호 건국대학교 교육대학원 1982 敎育論叢 Vol.2 No.-

1. In the past, the leadership type of the elementary school teachers was generally autocratic one. We can find that autocratic type mixed with democratic type and the democratic leadership type are gradually coming into being. 2. Young and high-educated elementary school teachers are inclined to follow the democratic leadership, while old and low-educated ones to follow the something similar to the autocratic leadership. And the questionnaire also says that much difference lies between the urban and the rural areas. 3. It also points out that as for the home education many pupils brought up under the democratic home education are from the parents young, high-educated, living in cities, while the other pupils brought up under autocratic home education are from the parents old, low-educated, living in small towns and villages in poor cultural facilities. 4. Many pupils in questionnaire think that the future desirable type of leadership should be a democratic one, while the elementary school teachers now accupied think that a desirable leadership type should be a mixed one(autocratic and democratic). I suppose this is the result due to the differences in consciousness structure between the generations. 5. The comparative analysis of the preliminary and the main study proved that autocratic types decreased from 35.2% to 16.0% and the democratic ones rapidly changed 7.8% to 50.7% in the past 10 years or so. From the above statements we find that our education is changing from autocratic type into democratic one, that nowdays a generation after the liberation the democratic leadership type is not widely used, that improvement in consciousness in structure takes more than a generation. It also suggests that the leadership in elementary school teachers is developing into a desirable one, that we have a bright future in education.

급성충소돌기염의 임상 : 병리학적 고찰

양기화,조준필,하영천,한진우,정학재,손수창,이성희,황재훈,신철호 최신의학사 1989 最新醫學 Vol.32 No.4

장간막의 염증성 근섬유모세포종 - 1예 보고 -

임성직,김교영,박재훈,김윤화,박용구,이주희,양문호 대한병리학회 1999 Journal of Pathology and Translational Medicine Vol.33 No.9

인체 체액내 황색포도상구균의 증식과 철 획득 기전

신성희,이강길,이명희,양남웅,임용,김진호 대한감염학회 2000 감염 Vol.32 No.5

기수법에서 진수의 변환

양성호,고영종 濟州大學校 師範大學 科學敎育硏究所 1997 科學敎育 Vol.14 No.-

In this paper, we investigate how to chang the base in numeration system as follows: 1) To change the base of p-adic number into p^(n)-adic number. 2) To change the base of p^(n)-adic number into p-adic number. 3) When gcd(n, m) = d, to change the base of p^(n)-adic number into p^(m)-adic number.

조기 양막 파수 신생아에 대한 임상적 연구

양은석,김강호,박상기,나창수 朝鮮大學校 附設 醫學硏究所 1989 The Medical Journal of Chosun University Vol.14 No.1

A clinical study was made on 157 newborns of mothers with premature rupture of membranes (study group) and 916 newborns of mothers without rupture of membranes (control group) at Chosun University Hospital from Jaunary 1987 to Decembcr 1988. The results were as follows: 1) The incidence of PROM was 14.6%. 2) 10.2% of all babies with PROM were born prematurely, significantly higher than the incidence of PROM in all newborn cases with 4.8% (P<0.005). 3) The incidence of neonatal sepsis in the PROM group (4.5%) was four times higher than in the normal group(1.1%) (P<0.005). The incidience was related to the gestational age at birth, and also increased with increasing time interval after PROM. 4) The incidence of neonatal asphyxia in PROM group (7.6%) was twice the normal group (3.6%) (P<0.025). The premature babies had greater incidence in both groups. Also, a positive correlation was found with increasing time interval PROM. 5) Neonatal respiratory distress syndrome(RDS) was found in 1.3% of babies with PROM, whereas 1.4% of babies in the normal group had the syndrome. Premature babies had higher incidence of RDS in both normal and PROM groups, but the latter had an incidence amounting the only 1/5 of the former. And it tended to diminish with creasing time interval after PROM.