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이주희,김제민,이상규,최수연,이주희,이영인,김지희 연세대학교의과대학 2023 Yonsei medical journal Vol.64 No.12
Purpose: Fractional microneedle radiofrequency (FMR) systems are used to treat inflammatory acne and scarring. Nonetheless, few controlled studies have combined this treatment with the traditional ablative fractional laser (AFL). We aimed to assess the safety and efficacy of the combination of FMR and AFL versus AFL alone in treating acne and acne scars. Materials and Methods: In this 20-week, randomized, split-face study, 23 Korean patients with facial acne and acne scars under went FMR and AFL treatments. One half of each patient’s face was randomly assigned to receive FMR+AFL, whereas the other half received AFL alone. Treatments were administered in three consecutive sessions at 4-week intervals. This study investigated the severity of inflammatory acne, acne scars, individual lesion counts, depressed scar volumes, as well as patient and physician satisfaction. In addition, five patients underwent skin biopsy, and sebum output was measured. Results: The FMR+AFL treatment demonstrated superior efficacy compared to AFL alone in terms of inflammatory acne and acne scar grading, lesion counts, and subjective satisfaction. The side effects were minimal and well-tolerated in both groups. Immuno histochemical findings from skin biopsy samples revealed that the application of FMR+AFL could induce an inhibitory effect on sebum secretion at the molecular level. Conclusion: FMR combined with AFL is a well-tolerated and effective treatment modality for inflammatory acne and acne scarring.
구순열 수술 후 흉터를 가진 영유아 환자에서 흉터 복합 레이저요법의 효과 및 안전성에 대한 단일 기관, 후향적 연구
이주희,최수연,김제민,이영인,이주희 대한피부과학회 2022 대한피부과학회지 Vol.60 No.7
Background: Postoperative scars following cleft lip surgery are frequently accompanied by cosmetic and functional problems; therefore, patients with cleft lip scars usually undergo various long-term scar treatment courses. Currently, only a limited number of fractional laser treatment cases of cleft lip scars have been reported. Objective: This study aimed to evaluate the safety and efficacy of the combination laser treatment for hypertrophic scar management following cleft lip surgery. Methods: This single-center retrospective study included 27 patients who underwent cleft lip surgery before 12 months of age. The control group comprising 13 patients received only a silicone gel or sheet for the scars, while the treatment group comprising 14 patients underwent laser treatment with a 1,550 nm non-ablative fractional erbium-glass laser, followed by a 10,600 nm ablative fractional carbon dioxide laser. Intralesional triamcinolone injection (5∼10 mg/mL) was administered immediately after laser treatment. Scar improvement was assessed at 1, 3, and 6 months after surgery using the Vancouver Scar Scale. Results: The mean total Vancouver scar scale showed a statistically significant improvement in the treatment group compared to that in the control group. In the sub-analysis of pigmentation, the vascularity, pliability, and height significantly improved in the treatment group. No differences in the patients’ baseline characteristics between the two groups were noted. No significant adverse effects were observed during the follow-up. Conclusion: Combination laser therapy using fractional lasers and intralesional triamcinolone injection is safe and effective for managing cleft lip surgery scars in infantile patients.
이주희,오성담 숙명여자대학교 자연과학연구소 2002 자연과학논문집 Vol.- No.13
Cabello가 제시한 얽힘의 맞교환(entanglement swapping)에 의한 양자 비밀 나눔(secret sharing)방식은 측정을 위한 특정 축이 필요 없고, 도청 확인을 하는데 합법적 사용자들(legal users)이 기존의 방식보다 적은 비트(bit)를 필요로 한다는 장점을 가지고 있다. Cabello는 그의 방식이 양자비밀 나눔과 키 분배가 동시에 일어날 수 있다고 주장했다. 그러나 우리는 2차원에서 부분적인 양자 키 분배가 이루어지고, 고차원에서는 양자 키 분배가 불가능하다는 것을 알 수 있었다. 보완성(security)을 검사하기 위해, 우리는 incoherent 도청 방식을 intercept-resend 도청방식과 man-in-the-middle 도청방식으로 나누고, 각 경우의 도청방식에서 도청이 인지되지 않을 확률들을 계산하였다. Quantum secret sharing scheme using entanglement swapping proposed by Cabello[1] has merits that do not have to select any specific axis for measurements and requires fewer bits for comparison among legal users to detect eavesdropping. He claimed that quantum secret sharing and quantum key distribution was possible simultaneously in his scheme, but we find that quantum key distribution is only partial in two dimension and impossible in the higher dimensions. To check security, we classify the intercept-resend attack and the man-in-the-middle attack in incoherent attacks, and then calculate the probability that eavesdropping is not detected for each attack.
해조류 청각(Codium fragile) 에탄올 추출물의 항산화에 관한 연구
이주희,김보애 국제문화기술진흥원 2019 The Journal of the Convergence on Culture Technolo Vol.5 No.4
Seaweeds are rich in in minerals, vitamins, proteins, and fiber, and are classified as green algae, and they are distributed on the coasts of Korea, East Asia, Oceania, etc. and are used as a health function material as well as food ingredients in our countries and countries. In this study, Codium fragile was extracted from ethanol and concentrated to confirm DPPH radical scavenging activity, SOD activity, FRAP and ABTS cation radical scavenging ability. As a result, DPPH scavenging activity was 0.83, 22.83, 38.27, 40.93, 45.60% at 6.25, 12.50, 25, 50 and 100 μg/mL, SOD-like activity were 23.13, 33.63, 33.93, 44.07 and 59.07%. FRAP and ABTS showed antioxidant activity in a concentration-dependent manner, as in the previous experiment. Therefore, this study confirmed that it can be used as a cosmetic material using Codium fragile, a natural material. 해조류는 무기질, 비타민, 단백질, 섬유소가 풍부하며 녹조류에 속하는 청각(Codium fragile)은 청각과이며, 우리나라, 동아시아, 오세아니아 등 해안에 분포해 있고 우리나라와 각국에서 식재료 뿐만 아니라 건강기능소재로 사용되고 있다. 본 연구에서는 청각을 주정으로 추출하고 농축하여 DPPH 라디칼 소거능, SOD 활성, FRAP과 ABTS 양이온 라디칼 소거능을 확인하였다. 그 결과 DPPH 소거능 측정 결과 6.25, 12.50, 25, 50, 100 μg/mL 농도에서 0.83, 22.83, 38.27, 40.93, 45.60%의 소거능을 나타냈으며, SOD 유사활성 측정 결과 23.13, 33.63, 33.93, 44.07, 59.07%의 유사활성능을 보였다. FRAP과 ABTS도 앞에서 했던 실험 결과와 마찬가지로 농도의존적으로 항산화 활성을 보였다. 따라서 본 연구결과에서는 천연 소재인 청각을 이용하여 화장품 소재로서 활용할 수 있음을 확인하였다.
이주희,변군혁,안상철 한국현대언어학회 2014 언어연구 Vol.30 No.1
This paper investigates the loanword adaptation patterns of Russian plosives in Korean. To discuss this issue, we observe the loan adaptation patterns of Russian in Seon-bong newspaper (from 1922 to 1937). As well documented in the literature (Avery and Idsardi 2001, Ahn and Iverson 2004), Korean employs a three-way obstruent system showing lax, aspirated and tense contrasts, whereas the plosive series in Russian is characterized by a different two-way contrast, i.e., plain voiceless, and voiced. There are certain common characteristics and differences among these two languages; Russian belongs to a [voice] language whereas Korean belongs to a [aspiration] language. Thus, Russian has the voicing distinction which Korean lacks. In this paper, we will propose typological adaptation in loanword contexts. More specifically, we first argue that the phonemic vs. phonetic mapping patterns can be decided based on the laryngeal typology of the target and the recipient languages. Then, we will show how the phonetic factors such as VOT and F0 function for the loanword adaptation, depending on the laryngeal typology. We also investigate the modern adaptation (The regulation for Russian loan from The National Institute from Korean Academy) patterns of Russian loanwords in Korean.
단절 및 거절 도식과 외로움의 관계: 거절민감성, 정서표현 양가성 및 친밀함에 대한 두려움의 매개효과
이주희,김영근 한국상담학회 2020 상담학연구 Vol.21 No.5
The purpose of this study was to examine mediating effects of rejection sensitivity, ambivalence over emotional expressiveness and fear of intimacy on disconnection and rejection schemas and loneliness through structural equation model. 414 university students from nationwide were selected as subjects for the study. The results of the study yielded a significant correlation between each variable. First, the result of individual mediating effect among factors showed that all the paths of rejection sensitivity through ambivalence over emotional expressiveness and fear of intimacy on relationship between disconnection and rejection schemas and loneliness were not significant. Second, disconnection and rejection schemas had the mediating effect by ambivalence over emotional expressiveness and fear of intimacy on loneliness. Third, it was found that rejection sensitivity, ambivalence over emotional expressiveness and fear of intimacy were mediated sequentially between disconnection and rejection schemas and loneliness. This study is meaningful that it empirically examined the necessity of practical intervention strategies focusing on observing the disconnection and rejection shema, anxiety of rejection, difficulties of emotional expression and fear of intimacy for the university students who complain loneliness. Based on the results, the implications and suggestions for follow up studies were discussed. 본 연구는 대학생의 단절 및 거절 도식이 외로움에 미치는 영향에서 거절민감성, 정서표현양가성, 친밀함에 대한 두려움이 매개하는지 구조방정식 모델을 통해 검증하고자 하였다. 본 연구를 위해 전국 지역의 대학생 414명을 대상으로 자료를 수집하였다. 연구 결과, 각 변인들 간에 유의미한 상관관계를 보였다. 첫째, 단절 및 거절 도식과 외로움의 관계에서 거절민감성과 정서표현양가성, 친밀함에 대한 두려움의 매개효과 검증 결과, 단절 및 거절 도식이 거절민감성을 거쳐 정서표현양가성과 친밀함에 대한 두려움으로 가는 경로가 유의하지 않은 것으로 나타났다. 둘째, 정서표현 양가성을 통해 친밀함에 대한 두려움을 매개하여 외로움에 유의미한 영향을 미치는 것으로 나타났다. 셋째, 단절 및 거절 도식이 거절민감성, 정서표현양가성, 친밀함에 대한 두려움을 순차적으로 매개하여 외로움에 영향을 미치는 것으로 나타났다. 본 연구를 통해 외로움을 호소하는 대학생들의 단절 및 거절 도식의 탐색과 거절에 대한 불안, 정서표현에 대한 어려움, 친밀한 관계에 대한 두려움에 초점을 맞춘 구체적 개입전략의 필요성을 경험적으로 살펴본 것에 의의가 있다. 이러한 결과를 바탕으로 본 연구의 시사점과 후속 연구를 위한 제언을 논의하였다.
발레프로그램이 일반 여대생의 하지(下肢) 유연성, 근기능 특성 및 형태에 미치는 효과
이주희,문달콤 한양대학교 우리춤연구소 2017 우리춤과 과학기술 Vol.13 No.4
본 연구는 일반 여대생들을 대상으로 10주간의 발레 프로그램을 실시하여 이들의 하지 유연성, 하지 근기능 특성 및 하지 형태에 미치는 발레프로그램의 과학적 효과를 규명하는데 그 목적이 있다. 연구의 대상자는 서울시에 소재한 여자 대학교에 재학중인 여대생들 중 사전검사를 실시하지 않은 자, 발목불안정성(CAIT) 진단 결과 중도 불안정성에 해당하는 자. 최근 3개월 이내에 하지외상의 병력이 있는 자를 제외한 발레군 9명, 비교군 9명, 총 18명의 대상자를 최종 대상자로 선정하였다. 발레 프로그램은 매트 워크(Floor Work), 바 워크(Barre Work), 센터 워크(Center Work), 정리운동(Warm down)으로 구성하였으며, ACSM의 권고에 따라 저항운동시 필요한 48시간의 회복시간을 두기 위하여 10주간 주3회 실시하였으며, 운동강도는 1~5주차에는 60분, 6~10주차에는 90분으로 점진적으로 증가시켜 진행하였다. 그 결과는 다음과 같다. 첫째, 10주간의 발레 프로그램 실시 후 유연성에서는 두 그룹(발레군, 비교군) 모두 시간에 따른 주 효과는 나타났으나, 시간에 따른 운동효과에 대한 그룹간의 교호작용 효과에는 유의미한 차이가 나타나지 않았다. 둘째, 10주간의 발레 프로그램 실시 후 좌측 무릎 굴근의 최대근력에는 유의미한 운동효과를 가지는 것으로 나타났으며(p<.05), 그 이외 하지 근기능 특성의 각 변인의 변화에는 차이가 나타나지 않았다. 셋째, 10주간의 발레 프로그램 실시 후 하지형태의 변화에는 차이가 나타나지 않았다. The purpose of this study is to determine the scientific effect of a ballet program which affects the flexibility of their lower limbs and the isokinetic muscular function and the forms of their lower limbs after carrying out a ten-week ballet program with general female university students. The study chose a total of 18 final subjects consisting of 9 ballet group subjects and 9 comparison group subjects except the students who did not receive a pretest, who were diagnosed with severe instability by Cumberland Ankle Instability Tool(CAIT) and who had a history of lower limb injuries within the last 3 months. The ballet program was composed of the Floor Work, Barre Work, Center Work and Warm down, and conducted 3 times for 10 weeks for 48-hour recovery time necessary at the time of a resistance movement according to ACSM's advice. Exercise intensity was gradually increased by 60 minutes during the 1st to the 5th week and by 90 minutes during the 6th to the 10th week. The results are as follows: First, after giving a 10-week ballet program, flexibility had significant key effects according to time both of the two groups, but interaction effects between groups on exercise effects according to time did not have significant differences. Second, after having a 10-week ballet program, the maximum muscle strength of the left knee flexor had significant exercise effects(p<.05), and except that, the change in each variable of the isokinetic muscular strength of lower limbs did not show differences. Third, after having a 10-week ballet program, the change in the forms of lower limbs did not show differences.