성균관대학교 멀티미디어 원격교육 시스템(배움 한마당) 개발에 관한 연구

김석수,권해문,이상권,김상진,전진호,황대준 成均館大學校 科學技術硏究所 1997 論文集 Vol.48 No.1

We propose SKKU Multimedia Distance Education System for distance education between nature science campus(Suwon) and social science campus(Seoul) in Sung Kyun Kwan University on DooRae (Distributed Object Oriented Multimedia Application Crafting Environment for Collaboration) framework (or platform). We support ONE : N study mode for a group lecture and discussion between two campus, and also we support mediation for floor mode of a group lecture and brain storming for floor mode of discussion. The communication portocol of this system is composed of TCP/IP and UDP, and the network type is composed of WAN(El line)for between the Suwon campus and Seoul campus, ATM LAN for each campus(local site). And, this system supports the application development of the collaborative multimedia environment connected with the various network in the CBM (Computer based Multimedia) based. Also, it does not restrict on space between a teacher(s) and a student(s) into cyberspace which made by network. This system has an interaction, late comer, a question and an answer, multi-session, application sharing and whiteboard which resembles chalkboard. Also, various supplementary functions such as video conference and voice conference for this system are what makes face-to-face education effective. Also it supports real or non-real type. The operation system developed on windows 95.

대퇴골두 골괴사를 동반한 슬관절 골괴사 : 증례 보고

송준민,이병일,나수균,신영수,최창욱,박종석,권희 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.1

본 순천향대학교 의과대학 정형외과학 교실에서는 2명의 환자에서 발견된 대퇴골두 골괴사와 함께 발생한 양측 슬관절 골괴사를 경험하였기에 보고하는 바이다. 대퇴골두 골괴사가 있는 환자에서 슬관절 동통을 호소하는 경우 연관통 등으로 여겨 간과하기 쉬우며, 대개 고관절의 통증으로 체중부하 보행이 어려운 경우가 많아 통증이 약하게 나타나기도 하기 때문에 관심을 가지고 슬관절 골괴사를 동반하는지 여부를 판단하여야 할 것이다. Osteonecrosis of the knee associated with osteonecrosis of the femoral head was very rare and reported cases were quite rare. We have experienced two cases of osteonecrosis of both knees associated with osteonecrosis of the femoral head. One is a 44-year-old man who had avascular necrosis of the righ femoral head and osteonecrosis of both knees, femoral condyle and metaphysis of proximal tibia. Another case is a 39-year-old man who had osteonecrosis of both femoral head and osteonecrosis of the both knees, medial condyles of both tibias. They were treated with total hip replacement arthroplasty for avascular necrosis of the femoral head and conservatively for osteonecrosis of the knee. If a person complains of pain in hip and knee simultaneously, we should pay attention and rule out osteonecrosis of the knee.

한우에 감염된 Theileria sergenti merozoite의 순수분리와 genomic DNA probe에 관한 연구

채준석,이주묵,권오덕,채건상 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.17 No.-

To make the genomic DNA probe of Theileria sergenti, the merozoites were purified from bovine crythrocytes. The infected erythrocytes were lysed by Aeromonas hydrophila(Ah-1) hemolysin, and the parasites were isolated by ultracentrifugation on a Percoll discontinuous density gradient. For construction of a T sergenti genomic DNA library, T sergenti DNA was digested with PstI and the fragments were ligated into the PstI site of pUC19 before transformation of Escherichia coli JM83. Out of thousands of transformants obtained by transformation of E coli JM83 with the genomic library, three plasmids were chosen. The sizes of the inserted DNAs were 2.9kb(2.4kb and 0.5kb) in pKTS1, 4.3kb in pKTS2 and 1.5kb in pKTS3, respectively. The DNA fragments used as probe KTS1(2.4kb), KTS2(4.3kb) and KTS3(1.5kb) were labeled digoxigenin-11-dUTP for the Southern hybridization. In Southern hybridization, all of the probes(KTS1, KTS2 and KTS3) reacted specifically to T sergenti DNA, but not to bovine leucocyte DNA. In order to find out the sensitivities of the digoxigenin-11-dUTP-labeled KTS1 and KTS3 as the probes, purified merozoite DNA and bovine DNA(control) were checked by dot blot hybridization with the probes. Both of the probes, KTS1 and KTS3, detected as minimum amount of 975pg of the T sergenti DNA, but not bovine DNA even to 500ng.

후궁성형술로 치료한 경추 척수병증 환자에서 방사선학적 소견이 예후에 미치는 영향

김석준,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.7

심상성 루프스에서 Nested-Primer Gene Amplification Assay에 의한 결핵균 DNA의 검출

신문석,전효진,김병천,이규석,김재룡,권호준,송준영 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Lupus vulgaris, which is a progressive form of postprimary tuberculosis in patients with a moderate to high degree of immunity and tuberculin sensitivity, is the most common, most serious, and most variable type of cutaneous and mucous membrane tuberculosis. Domonstration of M.tuberculosis directly or in culture in some of these eruptions can be difficult. It is essential to demonstrate the presence of M.tuberculosis in a clinical sample for a definitive diagnosis of tuberculosis. With the discovery of the polymerase chain reaction (PCR), the DNA diagnostic approach for infection has developed in a short period. With the dual purpose of definitive and rapid diagnosis of tuberculosis, this study examined the usefulness of a nested PCR for detection of M. turberculosis. Compared with a single-step PCR, the two-step PCR was able to enhance sensitivity approximately 1,000-fold on the basis of bacterial counts and DNA quantity. We concluded that two-step nested PCR appeared to be the most useful PCR protocol for early and sensitive diagnostic method detecting M.tuberculosis in acid-fast stain negative specimens.

영아에서 발생한 골수섬유증 1례

최성민,이동석,권경배,김두권,김나연,원유흥,이준희,권영무 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

특발성 골수섬유증은 만성 골수증식성 질환의 하나로 말초혈액도말에서 백적아구증, 부동변형적혈구 눈물방울세포 소견을 보이며, 골수 생검상 망상 섬유와 교원섬유로 구성된 섬유조직이 증가하는 골수의 섬유화 소견을 보이며, 골수외 조혈작용으로 인한 대상적 비장·간장 종대를 특징으로 하는 소아에서는 극히 드문 질환이다. 저자들은 본원에 복부종괴와 안면창백으로 입원하였던 8개월된 남아에서 임상증상, 말초혈액검사, 골수생검에서 특발성 골수섬유증으로 진단되어 Methylprednisolone 대량 정주 요법으로 치료하였으나 진단7개월만에 패혈증과 심부전으로 사망했던 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Idiopathic myelofibrosis is a chronic myeloproliferative disorder characterized by anemia, leukoerythroblastosis, anisopoikilocytosis, tear-drop cell, extramedullary hematopoiesis with hepatosplenomegaly and varying degrees of myelofibrosis of bone marrow. The mean age is about 60 years, and pediatric cases are rare. We experienced a case of idiopathic myelofibrosis in a 8 months old male who was presented with pallor, huge splenomegaly, leukoerythroblastosis in peripheral blood, myelofibrosis in bone marrow biopsy. We presented a case of idiopathic myelofibrosis with brief review of the literatures.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

외부 프리스트레스 도입에 의한 노후된 콘크리트 거더교의 보강성능평가

박승범,홍석주,이봉춘,장석호,권혁준 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.1

One of the promising methods to enhance the flexural strength of a externally prestressed girder is to place the tendons with large eccentricities. The analysis and design of composite girders prestressed by external tendons involve difficulties related mainly to the position of anchorages and the construction sequences. This study was conducted on the concrete bridges reinforced by the continuous girders and the external prestressing. The test results in this study showed that the external prestressing of a composite girder increased the range of the elastic behavior, reduced deflections, increased ultimate strength, and added to the redundancy by providing the multiple stress paths.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

크론병에 대한 CoPPLX의 방어효과에 대한 연구

이호학,김유림,문창기,이재일,양병윤,김종수,이정민,정재혁,안석진,박상준,김윤권,김소연,김영중,조민구,최영자,장성조 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1