RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 음성지원유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        정신분열병에 대한 리스페리돈의 효과 및 안정성

        이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

        연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

      • KCI등재후보

        개에서 이중 결찰법을 통한 동맥관 개존증의 완치 예

        윤헌영,정순욱,박희명,박철,정만복,김준영,한현정,황민,노병국,박상혁,장하영,박정윤 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1

        A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary teaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 U/L), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasonographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.

      • KCI등재

        단일 치근을 가진 하악 제1유구치

        윤상일,최형준,김성오,이제호,손흥규 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

        본 증례에서는 단일 치근을 가진 하악 제1유구치에 대해 서술하고자 한다. 5세 남아의 하악 제1유구치는 방사선 사진 검사결과 양측성으로 분명한 단일치근을 가진 것으로 나타났다. 보통 상악 구치는 3개의 치근을, 하악 구치는 2개의 치근을 가지나, 치아의 발육시기도중 Hertwig상피근초가 제 시기에 적절히 함입되지 못하면 치근이 서로 나뉘지 못하여 치근의 융합이 발생될 수 있다. 융합된 치근을 가진 구치는 정상적인 구치보다 불리한 치관-치근 비율을 가질 뿐 아니라, 여러 보고에 의하면 융합된 치근을 가진 사람은 다수 치아의 선천적 결손이나, 상악 전치에서 치내치가 발현될 확률이 높아 예방적 치과 치료가 필요할 수 있다. 그리고, 외배엽이형성증, 합지증, 만지증, 청색공막증과 같은 전신 질환과 연관되어 나타날 수도 있다고 한다. 치근융합은 유전적으로 상염색체 열성 유전을 따른다고 밝혀진 바 있다. 현재까지 단일 치근을 가진 구치는 대부분 영구 구치에서 많이 보고된 바 있지만, 유구치에서는 거의 보고된 바가 없기에 이에 보고하는 바이다. In this case, we would like to discuss about the single rooted deciduous mandibular first molar. The deciduous mandibular molar of a five years old boy was shown to have a single root, bilaterally. Ordinarily, the maxilary molars have three roots and the mandibular molars have two roots. However, when the hertwig's epithelial root sheath do not invaginate properly during tooth development, root fusion can occur from the absence of root separation. Molars with fused roots not only have unfavorable crown to root ratio, but also according to many reports, have higher probability of having multiple congenitally missing teeth or dens invaginatus in the maxillary incisors, consequently requiring preventive dental treatment. In addition, disorders such as ectodermal dysplasia, syndactyly, clinodactyly, bluish sclera can also be related to this condition. Root fusion is known to be of autosomal recessive inheritance. Up to date, single rooted molars have been reported several times in permanent dentitions but hardly in deciduous dentition, which is the motive for this paper.

      • [TEACOOH]-Montmorillonite 층간화합물의 형성 및 층 내에서의 고분자화 반응

        윤도우,조성준 배재대학교 공학연구소 2005 공학논문집 Vol.7 No.1

        Na-Montmorillonite와 10-Carboxy-n-decyltriethylammonium bromide (유기 양이온) 사이의 양이온 교환반응에 의해 얻어진 [TEACOOH]-Montmorillonite 층간화합물을 유기 단분자인 ε-caprolactone을 반응시켜 [TEACOOH]-ε-caprolactone-Montmorillonite 층간화합물을 형성하였다. 이렇게 얻어진 [TEACOOH]-ε-caprolactone-Montmorillonite 층간화합물을 220oC의 온도 하에서 48시간 동안 가열하여 고분자화시켜 무기물질인 몬모릴로나이트와 유기 고분자인 폴리카프로락톤이 화학적으로 결합된 몬모릴로나이트/폴리카프로락톤 나노복합재료를 제조하였다. 고분자화반응을 수행한 후 얻어진 시료를 메탄올을 이용하여 추출한 뒤 고진공 하에 65oC로 24 시간 동안 건조시킨 후에 얻은 층간거리 값으로는 34.24 Å이 얻어졌다. [TEACOOH]-Montmorillonite intercalations complex obtained from Na-Montmorillonite and 10-Carboxy-n-decyldimethylethylammonium bromide(organic cation) was reacted with the monomer(ε-caprolactone) to achieve the [TEACOOH]-ε-caprolactone-Montmorillonite intercalations complex. From this intercalations complex Montmorillonite/Polycaprolactone Nanocomposite in which montmorillonite(inorganic material) is chemically linked with the polycaprolactone(organic polymer) was formed at 220oC for 48 h. The basal spacing for the sample obtained after polymerization, extraction with methanol and dried at 65oC in high vacuum for 24 h was 50.7 Å.

      • SF-36을 이용한 농촌 노인들의 건강상태 평가

        전진용,김상아,박웅섭,오미경,홍윤미 관동대학교 의과학연구소 2001 關東醫大學術誌 Vol.5 No.1

        This study was conducted to understand health status by general characteristic, and to find out relationship between the general characteristics and rural elderly's health status. Health status was measured using SF-36(Medical Outcome Study Short From 36). The finding of this study were as follow; Mean scores of health status by sex were higher in male on physical function, social function and role limitation-emotion. The elderly educated more reported good health on physical function, role limitation-physical, vitality, bodily pain and general health than did the elderly educated less. The elderly who have disease reported bad health on social function, mental health and general health. Therefore we reviewed the evidence that sex, education and illness are associated with health status in the elderly, and that specific public health service that related such condition should be considered for the rural elderly.

      • 지역사회교육을 위한 농촌폐교시설의 활용방안에 관한 연구

        윤준상,이창식 公州大學校 産業開發硏究所 1998 産業開發硏究 Vol.6 No.-

        Because of reduction of population in rural area, primary schools in that area are exposed to many problems and the environment of education of rural area has been deterrioration. In this situation, many cases of mergeer and abolition(M&A) of primary school in rural area were reported. The aims of this study were to define the concept of Community Education and to review, factors and method, the situation and problems of M&A and to suggest the policy direction to the M&A in rural area for the Community Education. This study was carried out through review of literature an statistical data collected from varioous sources. The major findings of this study were as follows: 1) The M&A of primary school is inevitable for change of placement standard to primary school and qualitative improvement of environment of education in rural area. 2) By the mobility of modern industrial society and the inequality between urban area and rural area in developing stage, necessity of M&A is increasing. 3) In this consequence, the number of abolished school is also increasing, and the relevant plan of utilization of facilities of abolished school is needed. Based on the results of the study, it was recommended that the M&A of primary school of rural area be changed to the Community Education Center. And comprehensive policy community education directions which include educational inevestment, public relation and gross social welfaree are to be formed.

      • 유도선수들의 개인별 특성에 따른 성취동기에 미치는 영향 : mainly university students

        윤익선,김진표,권성준 龍仁大學校 武道硏究所 2002 武道硏究所誌 Vol.13 No.1

        This investigation used questionnaire which amended and made up for TSMI(Taikyo Sport Motivation Inventory) to verify what effect judo champions personal trait has on accomplishment motive. The subject of the study was 406 men, women judo champion's in Seoul and Kyung-Ki province. The personal trait which is an independent variation was set up as sexual distinction, grade, athlete career, economic standard, record of winning a prize and weight. According to this, the dependent variable for accomplishment motive to find out about accomplishment motive was foxed as competition, ambition, effort and self-confidence and the result of the research is followed as below. Firstly, there seemed to exist a significant difference in competition(p<.001), standard of ambition(p<.006) and self confidence(p.006) in accomplishment motive according to sexual distinction. Secondly, a significant difference in standard of ambition(p<.001) existed among the dependent variable of accomplishment motive according to grade. Result of Scheffe's pre-verification was that significant difference seemed to exist in 4th grade with the 1st and 3rd grade. Thirdly, all of the dependent variable; competition(p<.001), standard of ambition(p<.001), effort(p<.003) and self confidence(p.006) showed significant difference in accomplishment motive according to athlete's career. Scheffe's pre-verification showed that significant difference in competition existed in between 5-8 years and 8-10 years, and significant difference in standard of ambition in between 3-5 years and 8-10 years and also 3-5 years and 5-8년 and over 10 years group existed. Also significant difference in effort showed in 5-8 years and 8-10 years. Fourthly, the accomplishment motive according to the economic levels showed significant difference only in standard of ambition(p<.05) which is a dependent variable. Fifthly, The accomplishment motive according to the career of winning a prize showed a significant difference in competition(p<.01), ambition(p<.01) and effort(p<.05) among the dependent variable, and also Scheffe's pre-verification showed a significant difference in more than 7 times, less than 3times and less than 7 times in ambition. Sixthly, the accomplishment motive according to weight showed a significant difference in competition(p<.001) and effort(p<.05) among the dependent variable, and Scheffe's pre-verification showed significant difference in middle weight class with the lightweight and middle lightweight class in competition.

      • KCI등재

        마이크로 프레스에 의한 미세 펀칭 홀의 디버링 특성

        윤종학,안병운,박성준 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.3

        In micro hole punching process the burr occurs inevitably, but the burr must be minimized in order to improve the quality 1 and accuracy of the product. In this study, magnetic field-assisted polishing technique is applied to remove the burr which exists in nozzles for ink-jet printer head and proved to be a feasible for deburring by experiment. The deburring characterisics of sheet metals was investigated changing with polishing time and magnetic abrasive size. After the deburring, the burr size has remarkably reduced and roundness of the hole also has improved.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼