PMSG를 투여한 미성숙랫드에 발생한 자궁축농증 발생례

김영홍 ( Young Hong Kim ),이근우 ( Keun Woo Lee ) 한국임상수의학회 2000 한국임상수의학회지 Vol.17 No.1

개에서 역행성 관류를 이용한 요관결석 제거술

양우종,장화석,정다정,이재훈,강은희,김대현,정욱헌,최치봉,김휘율 한국임상수의학회 2011 한국임상수의학회지 Vol.28 No.1

A Shihtzu (6-year-old, intact female) was referred to Konkuk University Teaching Animal Hospital for cystic calculus and hydronephrosis of right kiney. The dog was suspected to have ureteral rupture and peritonitis. Radiographic findings included cyctic calculi and right kidney enlargement. On ultrasonographic examination hyperechoic mass with severe acoustic shadowing was located in the right proximal ureter which was dilated. Hydronephrosis of the right kidney, right ureteral caculus and cytic calculus were confirmed by radiography and ultrasonography. Cystotomy for removal of calculus in the bladder and ureterotomy for removal of calculus in the right ureter were performed. Excretory urography (EU) performed one month after surgery revealed that the right ureter was homogeneously opacified and decreased to 3 to 6 mm in diameter. Surgical removal of ureteroliths was appropriate treatment for the ureteral and cystic calculi. The result suggests that ureterotomy is effective treament for the dilation and calculi of ureter.

활 전복 수입에 의한 전복허피스바이러스감염증(abalone herpes-like virus) 유입 위험평가

박선일 한국임상수의학회 2014 한국임상수의학회지 Vol.31 No.1

Abalone herpes-like virus (AbHV) is a fatal disease of abalones that impose severe economic impacts onthe industry of infected regions due to high mortality. The aim of this study was to quantify the risk of introducingAbHV into Korea through the importation of live abalones for human consumption by import risk analysis (IRA). Monte Carlo simulation models were developed to provide estimates of the probability that a ton of imported abalonecontains at least one AbHV-infected individual, using historical trade data and relevant literatures. A sensitivity analysiswith 5,000 iterations was also conducted to determine the extent to which input parameters affect the outcome ofthe model. Although many uncertainties were present in the data, the results indicated that, if 5,000 tons of abalonewere imported from a hypothetical exporting country with low prevalence of AbHV (model 1), there would be atleast one AbHV-infected abalones in 4,816 of those tons (96.3%), while there would be at least one AbHV-infectedabalones in 100% of those tons imported from country with high prevalence (model 2). Sensitivity analysis indicatedthat for model 1, prevalence was the strongest influence factor on the predicted number of infections. For model 2,background mortality and washing to reduce the risk of surface contamination during processing were the majorcontributing factors. Risk management strategies need to be enforced to reduce the risk of AbHV introduction in thatat least one infected abalone would remain in a consignment from country even with a low prevalence of AbHVinfection. The methodology and the results presented here will contribute to improve the development of AbHVmanagement program, and with more accurate data this IRA model will aid science-based decision-making on mitigationstrategies to reduce the risk of AbHV introduction in Korea.

노령견에서 발생한 거대 비장 혈종 증례 보고

정태호,최춘기,박철,최을수 한국임상수의학회 2016 한국임상수의학회지 Vol.33 No.4

A 10-year-old intact female, mixed breed dog presented with abdominal distention of 2 months durationand three days of decreased appetite. The patient was conscious and no other gross abnormalities were noted. A tentativediagnosis of idiopathic massive hematoma or hemangiosarcoma was made on evaluating all clinical findings. Splenectomy was performed for treatment of abdominal distention and histopathological investigation was initiated toconfirm the diagnosis. The hematoma was extremely massive on gross morphology, with the size of 20.2 × 12.4 cmand the splenic mass was diagnosed as hematoma formation, with moderate to marked lymphoid hyperplasia andadjacent moderate extramedullary hematopoiesis, based on microscopic description of spleen histology. This is the firstcase report in veterinary literature of a dog with extremely rare splenomegaly, an unusually large hematoma, withno malignancy or remarkable clinical signs.

Dermatitis Caused by Candida albicans in a Captive Spotted Seal (Phoca largha)

어경연,권오덕 한국임상수의학회 2014 한국임상수의학회지 Vol.31 No.4

Candidiasis caused by Candida albicans is a localized mucocutaneous disease. It occurs worldwide in variouskinds of animals. A 7-year-old male spotted seal weighing 98 kg showed facial skin lesions. The present case wascharacterized by erythematous, thickened, and alopecic skin lesions in the periocular region and on the commissureof the lower lip. For diagnosis, skin scraping and culture of samples from the facial skin lesions were done. Colonieswere cream-colored and glistening after 3 days of culture on Sabouraud dextrose agar. Typical yeast-like cells wereobserved by microscopic inspection after Gram staining. Recovery was achieved with itraconazole (1 mg/kg SID) for7 days, repeated three times at 2-week intervals.

Safety Evaluation of Epimedium koreanum Water Extract in Sprague-Dawley Rats

김주완,임미경,김홍태,구세광,장혜숙,오태호,이근우 한국임상수의학회 2010 한국임상수의학회지 Vol.27 No.2

To evaluate of oral toxicity of Epimedium koreanum nakai (EKN) water extract, three doses of EKN water extract (10, 100 and 1000 mg/kg/day) were administered to healthy Sprague-Dawley rats for 4 weeks. The results showed that there are no abnormal signs during the experimental period. The weights of testis and epididymis were increased dose-dependently, but seminal vesicle was decreased compared with control group. In hematology and serum chemistry, changes were observed within the normal ranges. In histological finding, slight to moderated changes were found but those were commonly or rarely encountered in the normal rats. These results suggest that no observed adverse effect level (NOAEL) of the oral application of EKN was considered to be more than 1000 mg/kg in SD rats under the conditions employed in this study.

개에서 전이성 악성형질세포종양

김방현,최재훈,정승우,김대용,윤화영,한흥율 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.4

A primary metastatic malignant plasma cell tumor was presented in a 7-year-old, female, mixed breed dog. The dog was admitted to Veterinary Teaching Hospital at College of Veterinary Medicine, Seoul National University after suffering from depression, anorexia, and dyspnea. The dog was euthanized due to poor prognosis. At necropsy, numerous, firm and tan round nodules, 1 to 2 cm in diameter were noted in the ribs. The nodules formed chain or were occasionally coalescing, causing osteolysis of the ribs. A large amount of clear fluid was present in the thoracic cavity. The spleen and liver were markedly enlarged and congested. Histologically, the nodular masses were diagnosed as plasma cell tumor which was believed to be originated from the rib. Evidence of metastasis was observed in the spleen, liver, and kidney.

Arterial and Venous Blood Gas, Electrolytes, Biochemical and Hematological Values in Healthy Korean Native Calves

이성환,옥승훈,권혁호,김두 한국임상수의학회 2015 한국임상수의학회지 Vol.32 No.6

The objective of this study was to investigate arterial and venous blood gas, electrolytes, biochemical, and hematological values in healthy Korean native calves (KNC). The healthy 62 KNC within 3 weeks-old were examined. The arterial blood was collected from caudal auricular artery and the venous blood from jugular vein. The blood samples were analyzed immediately using a portable blood gas analyzer. The pH, pO2, pCO2, cHCO3 −, BE, cSO2, Na+, Ca2+, Cl−, anion gap potassium (AgapK), Hct, cHgb, glucose, lactate and creatinine were determined. The normal values for blood gas, electrolytes, biochemical, and hematological variables determined in this study agree with other published values for normal calves. The mean concentration of glucose and lactate within 3 weeks old of KNC is higher than those of adult cattle. The blood values according to weeks of age within 3 weeks-old of arterial and venous blood variables were not significantly different (P > 0.05). Glucose (r = 0.927) had the strongest correlations between arterial and venous values. The correlation between the values of the arterial and the venous blood was strong in creatinine (r = 0.925), lactate (r = 0.815), Ca2+ (r = 0.806), Hct (r = 0.799), Na+ (r = 0.790), cHgb (r = 0.786), base excess (r = 0.749), pH (r = 0.710), HCO3 − (r = 0.710), and cTCO2 (0.663). Analysis of blood samples in a field condition, using hand-held analyzer is rapid and useful in bovine practice.

Micro Total Hip Replacement in Two Dogs with Legg-Calvé-Perthes Disease

노윤석,허수영,윤장원,박지영,정성목,이해범 한국임상수의학회 2017 한국임상수의학회지 Vol.34 No.6

A Maltese (case 1) and a Pomeranian (case 2) presented with acute right and left hind limb weight-bearing lameness. On physical examination, they exhibited severe pain and crepitus on the coxofemoral joint of affected hind limb. In addition, decreased thigh girth measurements were noted compared with the opposite leg. Radiological exam revealed necrotic areas in the femoral head of affected hind limb. These dogs were diagnosed with Legg-Calvé-Perthes disease (LCPD). The dogs underwent micro total hip replacement (THR). After surgery, at 3 years (case 1) and 7 months (case 2), both dogs recovered normal activity. The thigh girth and lameness scores were apparently improved in the affected limbs of both dogs. No complications of prosthesis implants, such as loosening, were noted. The clinical outcomes of these cases indicate that dogs with LCPD can be successfully treated with micro THR and have a good prognosis immediately after surgery.

분산분석

박선일,오태호 한국임상수의학회 2010 한국임상수의학회지 Vol.27 No.1

Analysis of variance (ANOVA) is a method to analyze the data from the experimental designs comparing two or more groups or treatments at the same time, and is the most effective tool of analyzing more complex data sets with different source of variations. This article describes the logic of ANOVA, the application of the method to the analysis of a simple data set, and the methods available for performing planned or post hoc multiple comparisons between the treatments means. In addition, the common misuse of the techniques is also discussed to emphasize that an inappropriate statistical analysis is potentially far more harmful than poorly conducted research. Lastly, an example is given for illustration purposes.