간헐식 흐름방식을 활용한 수직 · 수평 습지의 정화효율 평가

주광진(Kwang Jin Joo),이동민(Dong Min Lee),김기중(Ki Jung Kim),조용철(Yong Chul Cho),장광현(Gwang Hyeon Jang),최이송(I Song Choi),오종민(Jong Min Oh) 응용생태공학회 2017 Ecology and resilient infrastructure Vol.4 No.3

본 연구에서는 부영양화의 원인이 되는 질소와 인의 제거 효율을 향상시킬 목적으로 광물질을 활용한 여재를 이용하여 호기, 혐기의 흐름조건을 만들어주기 위한 수직·수평 흐름 인공습지를 고안하여 아크릴 반응조로 제작한 후 성능평가를 진행하였다. 수직·수평 흐름형 인공습지의 경우 호기 및 혐기조건을 평가하기 위해서 반응조 내 용존산소(DO) 농도를 측정해본 결과 호기상태에서는 2.7 ㎎/L, 혐기상태에서는 N.D로 확인되어 목적에 부합된 결과가 확인되었다. 실험결과에서는 SS 저감효과가 140 min, 80 min, 60 min의 운전시간에서 각각 94%, 91%, 61%의 효율을 보였고, T-P의 경우 각각의 운전시간에 따라 84%, 71%, 63%의 저감효율을 보였다. 또한 T-N의 경우 각각의 운전시간에 따라 63%, 49%, 42%의 저감효율을 보여 기존의 습지가 12~24 hr 체류시간을 가지는 것에 비하여 짧은 운전시간에도 높은 처리효율을 보이는 것으로 확인되었다. 본 연구에서는 수직·수평 흐름 방식을 복합 적용하여 기존 인공습지의 단점을 보완하기 위해 기술개발을 진행한 것으로 어떠한 기능적 효과를 갖는지 확인하였고, 향후 이에 대한 현장적용을 위한 운영 및 관리적 차원의 메커니즘 연구가 추가로 진행 될 필요가 있다. Nitrogen and phosphorus are key factors in causing eutrophication of water body. In this study, ceramics media was selected to increase the removal efficiency of nitrogen and phosphorus. We designed vertical, horizontal flow constructed wetlands to create aerobic and anaerobic flow conditions by using the media, then proceeded to performance evaluations after acrylic reactors were produced. In the case of vertical and horizontal flow constructed wetlands, we measured oxygen concentrations to evaluate aerobic and anaerobic conditions. we got the result of 2.7 ㎎/L in the aerobic condition, N.D in the anaerobic condition respectively, which suited our purpose. The result of the combined vertical and horizontal flow condition showed that the removal efficiency of SS was 94%, 91%, 61% at 140 min, 80 min, 60 min of running times, respectively, and the removal efficiency of T-P was 84%, 71%, 63% during each running time. In case of T-N, the removal efficiency was 63%, 49%, 42% during each running time. We found that the reactor exerted better removal efficiency when in the short time compared to 12 - 24 hr residence time of existing wetlands. In this study, we conducted experiments to explore functional effects after applying combined vertical and horizontal flow methods in the field. Further study will be carried out to identify its mechanism and administrative perspective.

Effect of Chromatin Changes in the Germinal Vesicle on the Development of Porcine Embryos In Vitro

Min‐Gu Lee,Rong‐xun Han,Jin‐Yu zhang,Yun‐Fei Diao,Reza K. Oqani,Dong‐Il Jin 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

In all the studies of mammalian species, chromatin in the germinal vesicle (GV) is initially decondensed with the nucleolus not surrounded by heterochromatin (the NSN configurations). During oocyte growth, the GV chromatin condenses into perinucleolar rings (the SN configurations) or other corresponding configurations with or without the perinucleolar rings, depending on species. During oocyte maturation, the GV chromatin is synchronized in a less condensed state before germinal vesicle breakdown (GVBD) in species that has been minutely studied. As not all the species show the SN configuration and gene transcription always stops at the late stage of oocyte growth, it is suggested that a thorough condensation of GV chromatin is essential for transcriptional repression. Because the GV chromatin status is highly correlated with oocyte competence, oocytes must end the NSN configuration before they gain the full meiotic competence and they must take on the SN/corresponding configurations and stop gene transcription before they acquire the competence for early embryonic development. In this study, we firstly investigated whether the layer of cumulus cells and size of oocytes could determine chromatin configurations in porcine oocytes. Using Hoechst3342 staining, the GV nucleolus and chromatin of porcine oocytes was classified into SN and NSN configurations. Next, we examined the changes in GV chromatin configurations during growth and maturation of porcine oocytes. In addition, the maturation and parthenogenetic development abilities in vitro were significant different between the SN and NSN configurations oocytes. These results indicated that chromatin changes in GV oocytes affect the development potential of parthenogenetic embryos.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

트레드밀 운동시 흡기근 테이핑이 폐활량에 미치는 영향

김민지,신수영,송월섭,조수진,최동락,황미진,황진규,박진현,김경,Dennis W. Fell 대구대학교 특수교육재활과학연구소 2011 再活科學硏究 Vol.29 No.1

이 연구는 트레드밀 운동과 키네시오 테이핑의 효과에 따른 폐활량의 변화를 알아보기 위해 26명의 비흡연자가 참가하였으며 키네시오 테이핑을 적용하지 않은 그룹과 키네시오 테이핑을 적용한 두 그룹으로 무작위로 배정하고 각 군들을 주 3회 6주간의 트레드밀 훈련을 실시하였다. 실험 전과 후, 스파이로미터를 사용하여 키네시오 테이핑의 적용 따른 폐활량 변화 효과를 측정하였다. 이 연구의 결과를 종합해보면 키네시오 테이핑을 적용 그룹에서 적용하지 않은 그룹에 비해 FVC, FEV1에서 유의한 증가를 보였다. 이러한 결과는 건강한 성인에서 키네시오 테이핑을 적용한 경우 키네시오 테이핑을 적용하지 않고 트레드밀 운동을 한 경우보다 폐활량의 향상에 효과적이라고 생각되어진다. The purpose of this study was to investigate the variation of vital capacity(VC) according to the effects of kinesio taping with treadmill exercise. Twenty-six non-smokers were participated in this research and these subjects were randomly assigned into two groups. To measure the VC variation effects of kinesio taping, spirometer was used. The collected data were analyzed statistically by using a paired Mauchly test and repeated measure ANOVA. The results of this study were as follows; A group: treadmill with kinesio taping B group: treadmill without kinesio taping. Between A and B, there were significant differences. In the case of A group, there was 11.66% increase of VC, during 3 weeks experiment(p<.01). In the case of B group, there were significant differences, 3.35% increase of VC, during 3 weeks taping intervention(p<.01). After 6 weeks experiment, the improvement of VC shown a significant difference with intergroup (p<.05). From this result, it was revealed that treadmill exercise with kinesio taping was effective to improve VC to healthy adult than treadmill exercise without kinesio taping.

고압멸균 처리시간에 따른 닭 체내 조류인플루엔자와 뉴캐슬병 바이러스의 멸균효과

이진주 ( Jin Ju Lee ),김동혁 ( Dong Hyeok Kim ),임정주 ( Jeong Ju Lim ),김대근 ( Dae Geun Kim ),민원기 ( Won Gi Min ),이후장 ( Hu Jang Lee ),장홍희 ( Hong Hee Chang ),김석 ( Suk Kim ) 한국예방수의학회(구 한국수의공중보건학회) 2011 예방수의학회지 Vol.35 No.4

Avian influenza (AI) and Newcastle disease (ND) distress a variety of avian species, especially domestic poultry. Severe syndromes are caused by highly virulent specific virus strains termed highly pathogenic AI and velogenic ND viruses, which are potential agrobioterrorism agents. This outbreak emphasizes the need for continuing cooperation between public health and veterinary medical communities in controlling AI and ND when it has a zoonotic potential. Up to date, the stamping out and burying system were applied for controlling methods against these highly infectious diseases in the ordinary way, however these methods had many environmental problems, including leachat and effluvium. Thus, we assessed that sterilization effect of AI and ND virus dependent on several treatment conditions, such as autoclaving time and cutting types of chicken. As a result, we found that the cutting type of chicken meat revealed a reduced HA titer (20) against both of AI and ND virus after 10 min of autoclaving, while whole chicken showed same titer after 30 and 60 min. Therefore, we propose that the conditions of treatment on infected chicken should be developed for convenient, affordable, and effective prevention methods against for AI and ND.

Layer-controlled thinning of black phosphorus by an Ar ion beam

Park, Jin Woo,Jang, Sung Kyu,Kang, Dong Ho,Kim, Doo San,Jeon, Min Hwan,Lee, Won Oh,Kim, Ki Seok,Lee, Sung Joo,Park, Jin-Hong,Kim, Kyong Nam,Yeom, Geun Young Royal Society of Chemistry 2017 Journal of Materials Chemistry C Vol.5 No.41

<▼1><P>BP thinning was carried out using a monoenergetic Ar<SUP>+</SUP> ion beam and the BP could be thinned without damaging the surface.</P></▼1><▼2><P>Black phosphorus (BP) is one of the most interesting two-dimensional (2D) layered materials due to its unique properties, including a band gap energy change from 0.3 eV (bulk) to 2.0 eV (monolayer) depending on the number of BP layers, for application in nanoelectronic devices. In general, 2D layered materials including BP have limitations in terms of synthesis due to the process factors such as time, temperature, <I>etc.</I>, and thus, a thinning technique from the bulk material to a 2D material needs to be used while controlling the removed layer thickness. In this study, layer-controlled thinning of BP was performed by using a controlled Ar<SUP>+</SUP> ion beam method and the BP thinning characteristics were investigated. By using the near monoenergetic ion energy in the range of 45–48 eV, BP could be thinned with the thinning rate of ∼0.55 nm min<SUP>−1</SUP> down to bilayer BP without increasing the surface roughness and without changing the chemical binding states. The BP oxide on the pristine BP could also be successfully removed using the same Ar<SUP>+</SUP> ion beam. 2D BP field-effect transistors (FETs) fabricated with the thinned bilayer–10-layer BPs exhibited electrical characteristics similar to those of pristine BP FETs suggesting no electrical damage on the BP layers thinned by the controlled monoenergetic Ar<SUP>+</SUP> ion beam.</P></▼2>

RSM을 이용한 비규격 제주산 양식 넙치(Paralichthys olivaceus)로부터 연제품의 가공 조건 최적화

김진수 ( Jin Soo Kim ),이동호 ( Dong Ho Lee ),신준호 ( Jun Ho Shin ),전유진 ( You Jin Jeon ),김형준 ( Hyung Jun Kim ),허민수 ( Min Soo Heu ),이지선 ( Ji Sun Lee ),박권현 ( Kwon Hyun Park ) 한국수산과학회(구 한국수산학회) 2011 한국수산과학회지 Vol.44 No.5

This study was conducted to optimize the processing of high quality surimi gel from unmarketable cultured bastard halibut Paralichthys olivaceus. According to endogenous enzyme activity and processing optimization, high quality surimi gel from unmarketable cultured bastard halibut was prepared by mixing 3.0% (w/w) salt, 2.4% (w/w) starch, 5.0% (w/w) egg white and 4.8% (w/w) ice water in a Stephan mixer, set at 5˚C for 24 h, followed by boiling for 30 min, and finally cooling for 30 min. The strength of the surimi gel from unmarketable cultured bastard halibut prepared by the above processing method was 1,257 g×cm, which was 33% higher than that of a commercial surimi gel from Alaska pollock, grade SA.

Use of Electroacupuncture at ST36 to Inhibit Anaphylactic and Inflammatory Reaction in Mice

Moon, Phil-Dong,Jeong, Hyun-Ja,Kim, Su-Jin,An, Hyo-Jin,Lee, Hye-Jung,Yang, Woong Mo,Park, Seong Kyu,Hong, Seung-Heon,Kim, Hyung-Min,Um, Jae-Young S. Karger AG 2007 Neuroimmunomodulation Vol.14 No.1

<P><I>Objective:</I> Electroacupuncture (EA) has been used to treat myalgia, allergy and gastroenteropathy in Korea. To determine whether EA can treat anaphylactic and inflammatory reactions, the effect of EA was investigated in a murine model. <I>Methods:</I> EA stimulation of the ST36 acupoint was performed for 10 min. Using a passive cutaneous anaphylaxis (PCA) model, the antianaphylactic effects of EA were examined. Interleukin-6 and tumor necrosis factor-α were measured using the ELISA method. The level of nuclear factor (NF)-κB/RelA protein and NF-κB DNA-binding activity was determined using the Western blot analysis and the transcription factor enzyme-linked immunoassay method. <I>Results:</I> EA inhibits PCA and β-hexosaminidase release, IL-6 secretion on the PCA, and in addition, EA reduces NF-κB DNA-binding activity. <I>Conclusion:</I> These results indicate that EA may possess antianaphylactic and antiinflammatory properties.</P><P>Copyright © 2007 S. Karger AG, Basel</P>

도심 수목원에서의 경관감상과 산책이 인체의 생리적 안정에 미치는 영향

박범진 ( Bum Jin Park ),가재남 ( Jae Nam Ka ),이민선 ( Min Sun Lee ),김선아 ( Seon A Kim ),박민우 ( Min Woo Park ),최윤호 ( Yoon Ho Choi ),정다워 ( Da Wou Joung ),권치원 ( Chi Weon Kwon ),염동걸 ( Dong Geol Yeom ),박순주 ( Soon Jo 한국산림과학회 2014 한국산림과학회지 Vol.103 No.4

This research was conducted to investigate the impact of viewing scenery and walking in the urban forest onphysiological relaxation of humans. The experiment was conducted in Hanbat Arboretum located in Daejeon, and thecontrol experiment was conducted in front of Daejeon City Hall. The subjects that participated in the experimentcomprised 24 Korean male university students in their 20s (average age, 21.1±2.5 years), participated in the experimentas the subject, and these subjects were classified into three groups divided into three locations such as the pine forest inArboretum, the pond in Arboretum, and the city. The subjects sat down and viewed scenery for 10 min, and they thenwalked for 15 min. Further, physiological changes were measured using indicators such as heart rate variability (HRV),blood pressure, and pulse rate. As a result, when subjects viewed scenery and walked in the urban forest, a statisticallysignificant increase in the high frequency (HF) power of HRV and decrease in systolic pressure was observed comparedwith when subjects viewed scenery and walked in the city. Through this research, it was found that activities like viewingscenery or walking in Arboretum of the city are effective in increasing the physiological relaxation of the city residents.