수학자 이상설이 소개한 근대자연과학: <식물학(植物學)>

박영민 ( Young Min Park ),김채식 ( Chae Sik Kim ),이상구 ( Sang Gu Lee ),이재화 ( Jae Hwa Lee ) 한국수학교육학회 2011 수학교육논문집 Vol.25 No.2

본 원고는 2004년 과학사학자 박성래 교수가 독립 운동가이자 한국 근대 수학교육의 아버지로 부르기 시작한 보재 이상설(李相卨, 1870-1917)이 자연과학에 기여한 내용을 다루고 있다. 한국수학사학회지 2009년 11월 호에 자세히 소개된 〈數理〉를 쓴 시기를 전후하여, 같은 시기에 이상설이 붓으로 쓴 것으로 여겨지는 〈植物學>(이상설, 1899)은 총 4면의 초록 필사본이며, 그 대본(臺本)은 〈植物學啓蒙〉 (Edkins, 1886)으로 영국의 Joseph Edkins(艾約瑟, 1823-1905)가 번역하여 1886년에 간행한 〈西學啓蒙〉 16종 가운데 하나이다. 이상설의 〈植物學>은 이 〈植物學啓蒙〉을 읽으면서 그 책의 내용 중 당시의 조 선 학자가 모르고 있던 새로운 내용을 중심으로 메모를 한 것으로 여겨진다. 본 연구에서는 전통산학과 근대서양수학을 연결하는 〈數理〉를 저술했으며. 우리나라의 정규 교과과정에 수학과 과학을 필수과목으로 지정하고, 첫 번째 수학교과서 〈산術新書〉를 발간함으로 당대 최고의 수학자로 평가된 이상설이 쓴 〈植物學〉을 발굴하여 그 내용과 의미를 최초로 분석한다, 이를 통하여 당시 조선의 서양 과학, 특히 식물학에 대한 이해 수준을 분석하고 〈植物學〉의 원전인 〈植物學啓蒙〉 과 <西學啓蒙〉의 저자에 대하여 알아본다. 이는 당시 수학교육자가 자연과학분야에 행한 교육적 기여를 이해 하는데 필수적인 연구이다. This paper deals with contents that Sang-Seol Lee contributed to the natural science in the 19th century Korea. Prof. Sung-Rae Park, the science historian, called Sang-Seol Lee Father of the Modern Mathematics education of Korea. Sang-Seol Lee wrote a manuscript Botany with a brush in late 19th century. Botany was transcribed from Science Primers: Botany (written by J. D. Hooker), which is translated into Chinese by Joseph Edkins in 1886. The existence of Sang-Seol Lee`s book Botany was not known to Korean scientists before. In this paper, we study the contents of Botany and its original text. Also we analyze people`s level of understanding Western sciences, especially botany at that time. In addition, we study authors of 16 Primers for Western Knowledge. We study the contribution of mathematician Sang-Seol Lee to science education in the 19th century Korea.

경북 최초의 신장이식 1례

이중현,김용섭,이정호,이창우,김상욱,이문섭,오민구,하달봉,이경섭 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

신장이식은 환자의 삶의 질을 높이고 거의 정상적인 사회생활을 가능하게 함으로써 말기신부전 환자의 3가지 신대체 요법(혈액투석, 복막투석, 신장이식) 중에 가장 효과적이고 각광받는 치료법이라 할 수 있다. 최근 들어 의료기술과 의학의 발달로 신장이식의 성공률은 과거에 비해 비약적으로 높아지고 있으며 국내에서도 점차 신장이식수술을 받는 환자가 증가하고 있으나 서울이나 다른 대도시에 비해 의료환경이 열악한 중소도시나 지방의 병원에서는 아직도 시행하지 못하고 있는 형편이다. 이에 저자들은 경북 최초로 자체 의료진에 의해 고혈압과 말기 신부전으로 동국대 포항병원에서 혈액투석을 받고 있던 32세의 남자환자에게 부인으로부터 신장을 제공받아 신장이식을 성공적으로 시행하였기에 문헌고찰과 함께 보고하고자 한다. Kidney transplantation is the preferred treatment modality for many patients with end-stage renal disease (ESRD), because it offers improved quality of life over both hemodialysis and peritoneal dialysis. Patients who do well after transplantation generally report improvement in vitality and freedom to return to the style of life that they experienced before their progression to ESRD. Recently, the success rate of kidney transplantation is greatly being increased as the surgical technique and immunosuppressive drugs are developed. Kidney transplantation is also popular in Korea which has good result. But, until now the general hospitals which are located at small city can't try the kidney transplantation because they don't have proper facilities and experts. We firstly experienced a case of kidney transplantation in a 32 years old man with hypertension and chronic renal failure at KyoungBuk province. So we report this case with references.

Effect of Chromatin Changes in the Germinal Vesicle on the Development of Porcine Embryos In Vitro

Min‐Gu Lee,Rong‐xun Han,Jin‐Yu zhang,Yun‐Fei Diao,Reza K. Oqani,Dong‐Il Jin 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

In all the studies of mammalian species, chromatin in the germinal vesicle (GV) is initially decondensed with the nucleolus not surrounded by heterochromatin (the NSN configurations). During oocyte growth, the GV chromatin condenses into perinucleolar rings (the SN configurations) or other corresponding configurations with or without the perinucleolar rings, depending on species. During oocyte maturation, the GV chromatin is synchronized in a less condensed state before germinal vesicle breakdown (GVBD) in species that has been minutely studied. As not all the species show the SN configuration and gene transcription always stops at the late stage of oocyte growth, it is suggested that a thorough condensation of GV chromatin is essential for transcriptional repression. Because the GV chromatin status is highly correlated with oocyte competence, oocytes must end the NSN configuration before they gain the full meiotic competence and they must take on the SN/corresponding configurations and stop gene transcription before they acquire the competence for early embryonic development. In this study, we firstly investigated whether the layer of cumulus cells and size of oocytes could determine chromatin configurations in porcine oocytes. Using Hoechst3342 staining, the GV nucleolus and chromatin of porcine oocytes was classified into SN and NSN configurations. Next, we examined the changes in GV chromatin configurations during growth and maturation of porcine oocytes. In addition, the maturation and parthenogenetic development abilities in vitro were significant different between the SN and NSN configurations oocytes. These results indicated that chromatin changes in GV oocytes affect the development potential of parthenogenetic embryos.

Sn-3.5Ag 땝납의 Zn첨가가 기계적 특성에 미치는 영향

이도재 ( Lee Do Jae ),이광민 ( Lee Gwang Min ),이경구 ( Lee Gyeong Gu ),오태욱 ( O Tae Ug ),백대화 ( Baeg Dae Hwa ) 한국주조공학회 2003 한국주조공학회지 Vol.23 No.6

N/A Effects of Zn concentration on the mechanical properties of Sn-3.5Ag solder were studied, and compared to those of Sn-40Pb alloy which is widely used currently in electronics industry. Aging treatments were performed at 100 and 150 for up to 120days and then were examined changes of microstructure by optical microscopy, SEM and EDS. Sn-3.5Ag solder was loaded to failure at cross head speed of 0.3 mm. min-1 to measure strength and elongation. Aging treatment changed more or less the tensile properties of the solder itself. In short, Sn-Ag base alloy showed decrease in tensile strength and increase in elongation with prolonged agig time. Sn-3.5Ag alloy showed more sensitive changes in tensile properties than Sn-3.5Ag-1Zn alloy by aging. On the other hand, Sn-40Pb alloy showed decreasing tendances in both tensile strength and elongation by aging.

보문 : 항고혈압성 안지오텐신 전환효소 저해제를 생산하는 새로운 효모의 선별 및 저해물질 최적 생산조건

강민구 ( Min Gu Kang ),김하근 ( Ha Kun Kim ),이성훈 ( Sung Hun Yi ),임성일 ( Sung Il Lim ),이종수 ( Jong Soo Lee ) 한국균학회 2011 韓國菌學會誌 Vol.39 No.3

Forty eight strains of yeast were cultured in potato dextorse(PD) broth at 30˚C for 24 hr and centrifuged with 12,000 rpm for 20 min. After concentrated the cultures, antihypertensive angiotensin I-converting enzyme(ACE) inhibitory activities of its concentrates were investigated. Among them, the concentrates from Saccharomyces cerevisiae Y183-3 showed the highest ACE inhibitory activity of 71.8%. The ACE inhibitor from Saccharomyces cerevisiae Y183-3 was maximally produced when Saccharomyces cerevisiae Y183-3 cultured in PD broth at 30˚C for 36 hr.

다양한 적송잎 추출물의 항생제 내성 황색포도상구균에 대한 항균활성 검증

Nam-Young Kim(김남영),Min-Kyung Jang(장민경),Myung Je Jeon(전명제),Dong-Geun Lee(이동근),HyeJi Jang(장혜지),Seung Woo Lee(이승우),Mihyang Kim(김미향),Sung Gu Kim(김성구),Sang-Hyeon Lee(이상현) 한국생명과학회 2010 생명과학회지 Vol.20 No.4

병원 내 감염의 주된 원인균으로 알려진 황색포도상구균(5. aureus)과 항생제 내성 황색포도상구균(PRSA, MRSA)에 대해 항균활성이 우수한 천연 항균성 물질을 검색하기 위해 적송잎을 대상으로 열수-헥산(HWH), 열수-에탄올(HWE), 헥산, 에탄올 및 열수 등으로 획득된 추출물들로 항균활성을 조사하였다. 헥산, 에탄올, 열수-헥산, 열수-에탄올 추출물들은 그람양성 대표세균인 고초균(B. subfilis), 황색포도상구균 표준균주, 항생제 내성균주인 PRSA 및 MRSA에 대해서 항균활성을 나타내었으며, 특히 MRSA (ATCC 33591) 균주에 대해 다른 균주들 보다 높은 항균활성을 나타냈다. 열수 추출물은 황색포도상구균 표준균주 및 MRSA에서만 항균활성을 나타냈지만, 항균활성은 가장 높아 50 ㎎/㎖의 농도에서 33 ㎜의 생육저해환을 나타냈다. 각 균주들에 대한 생장의 최소저해 농도(MIC)는 HWH 및 HWE 추출물이 모두 0.05 ㎎/㎖의 농도로 가장 낮았고, 열수추출물이 0.5 ㎎/㎖의 농도였으며, 에탄올 추출물은 5 ㎎/㎖의 가장 높은 농도를 나타냈다. 모든 추출물들은 121℃에서 20분간의 열처리 후에도 항균활성이 유지되었으므로 열에 대해 안정한 물질임을 알 수 있었다. 본 연구결과로 식품산업에서 솔잎 추출물을 천연 항균제로 사용할 수 있을 것으로 기대할 수 있다. investigated antimicrobial activities of various pine (Pinus densiflora) needle extracts against antibiotic resistant strains of Staphylococcus aureus. Hot water extract showed the highest antimicrobial activity against normal and methicillin resistant Staphylococcus aureus (MRSA), however, it exhibited no antimicrobial activity against penicillin resistant S. aureus (PRSA). Hot water-hexane (HWH), hot water-ethanol (HWE), hexane, and ethanol extracts showed antimicrobial activity against S. aureus, PRSA and MRSA. Minimum inhibitory concentrations (MIC) of HWH, HWE, hexane, and ethanol extracts were 0.05, 0.05, 0.5 and 5 ㎎/㎖ respectively, and HWH and HWE extracts showed the strongest antimicrobial activity among these extracts. Antimicrobial activities of pine needle extracts were stable after heating at 121℃ for 20 min. These results suggested that pine needle extracts can be used as an effective natural antimicrobial agent for food and medical industries.

찬물 강제수영이 남성화된 암컷 생쥐의 통각예민도에 미치는 영향

이국희,박제민,김명정,양구범,전명호 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.1

The aim of the study was to test the hypothesis that the mice androgenized in their perinatal period show in their later life heightened basal pain sensitivity and lowered analgesic effect induced by cold water swim. Entered into the experiment were 29 female mice androgenized by intraperitoneal injection of 100㎍ testoste-rone propionate within 24 hours after birth and 30 female mice given with intraperitoneal injection of the same amount of normal saline as the control group. On 160th day after birth, the pain sensitivity was measured in terms of the tail flick latency using 52±1℃ water before and after forced swim in cold water(15±1℃) for six minutes to see the change of the pain sensitivity. The results were as follows 1) The androgenized mice revealed significantly heightened basal pain sensitivity as compared to the control mice. 2) The lowering effect of the pain sensitivity by cold water forced swim was significant in both the androgenized and the control groups, but the effect was significantly less in the androgenized mice than in the control group. From these results, the author suggests that the androgenized female mice exposed to the testosterone in the neonatal period have heightened basal pain sensitivity and lowered cold water swim-induced analgesia than the normal female mice in their later lives.

횡문근융해증과 경한 신손상을 동반한 급성 A형 간염 1예

조규민,김창욱,성현진,허준,전부석,이종환,심은희,이석종,이창돈 영남대학교 의과대학 2012 Yeungnam University Journal of Medicine Vol.29 No.1

A 48-year-old male visited the emergency room of the authors’ hospital due to nausea, vomiting, and myalgia for four days. Acute hepatitis A was identified from the serologic marker of the hepatitis A virus. Mild elevation of the serum creatinine and creatinine phosphokinase(CPK) suggested rhabomyolysis, which was confirmed with the serum aldolase, myoglobin, and urine myoglobin. With supportive care, both the liver and renal func- tions were recovered gradually and fully. This case shows that rhabdomyolysis can be one of the mechanisms of renal complication in cases of acute symptomatic hepatitis A.

친환경농업 시범마을에 대한 환경영향평가

이남종,고병구,노기안,한민수,김민경,곽한강,박문희 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

1999년부터 2001년까지 3년간 친환경농업 시범마을에 적용되고 있는 INM (Integrated Nutrient Management) and IPM (Integrated Pest Management) 실천에 따른 추진효과를 분석하기 위하여 시범마을로 지정된 옥천과 양평지역의 농가 포장에서 시비량, 양분유실 및 생태계 변화 등을 조사 분석하였다. 3요소 시비량은 토양검정시비로 인하여 농가관행시비와 비교하여 28.6~39.4% 절감할 수 있었으며, 쌀 수량도 시비량이 비교적 적은 토양검정 시비구에서 3~10% 증수하였다. 영농기간동안 토양 침투수중 NO₃-N 농도는 농가관행 시비구 2.9 ㎎/L에 비하여 토양검정 시비구는 1.5 ㎎/L로 감소하였으며, 시범마을 논으로 유입되는 관개수의 COD, NH₄-N, NO₃-N 농도는 각각 15.0, 0.67, 1.39 ㎎/L, 시범마을 논에서 배출된 용수는 각각 12.4, 0.29, 2.42 ㎎g/L로 감소되는 경향이었다. 처리별 수서곤충, 환형동물, 패류 및 감각류 등의 개체수는 농가관행구 100에 대하여 토양검정 시비구 293, 토양검정과 개량제 혼용구 276, 무비구 90으로 토양검정 시비구에서 많았으며 수서 무척추 동물은 관행농업을 수행하고 있는 지역을 100으로 볼 때 친환경농업마을은 242와 443으로 INM과 IPM을 실천하는 시범마을에서 생물종이 다양하고 그 개체수가 많은 것으로 나타났다. 친환경농업 시범마을 조성 후 작물 추천시비량 준수와 적기 예찰을 통하여 필요이상 사용되는 비료와 농약을 절감하여 생태계의 개선과 토양이 건전화된 것으로 평가되었다. In order to preserve the soundness of ago-ecosystem and products safety in agriculture, this study was evaluated environmental impact in relation to the INM (Integrated Nutrient Management) and IPM (Integrated Pest Management) at paddy fields at Ok-Chun and Yang-Pyung region. By introduction of INM with the application of BB(bulk-blanded) fertilizer based on soil analysis and EM, the application rate of fertilizer was reduced to about 28.6-39.4% and the yield of brown rice was increased to about 3-10% compared to conventional practices. The concentrations of COD, NH4-N, and NO3-N in irrigation water flowed to the environmental-friendly agriculture practices were 15.0, 0.67, and 1.39 ㎎/L, respectively. The concentrations of COD, NH₄-N, and NO₃-N from paddy fields in drainage water were 12.4, 0.29, and 2.42 ㎎/L, respectively. The total number of the freshwater invertebrates was higher in field treated with fektilhtion by prescription with soil testing. Also, the population density of aquatic insects was higher than the other fields at both demonstration villages. In conclusion, it was possible to reduce the amount of fertilizer and agricultural chemicals application, and increase the yield of rice by application of the environmental-friendly agriculture practices.

신주위 공간 및 요근을 침범한 췌장성 가성낭포 1례 : 진단및 경피적 배액술 Diagnosis and Percutaneous Drainage

이현경,오연희,이원재,한동선,오민구,이성우,박수성 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

Pancretic pseudocyst is a well-known complication of pancreatitis and may occur in unusual locations. Involvement of the left perirenal space and psoas muscle is rare. Radiologic findings and management of a surgically proven case of pancreatic pseudocyst extending to left perirenal space and psoas muscle is described.