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Polaron Hopping in the K_(2)O · B_(2)O_(3) · V_(2)O_(5) Glasses
차유정,강재필,홍성덕,김복수,김영훈,서용문,송승기 명지대학교 자연과학연구소 2005 자연과학논문집 Vol.24 No.-
K_(2)O · B_(2)O_(3) · V_(2)O_(5) 계 유리의 조성비에 따른 밀도, 굴절율, 전이온도, 천이금속이온비율 등과 직류 전기 성질을 100~450K 온도영역에서 연구하였다. 실험결과를 비정질 반도체에 관한 전기전도에 대한 이론 모델을 이용하여 분석하였다. 고온 영역에서는 직류전도도의 온도 의존성을 Mott의 포논-도움껑충뛰기 전도모델로 분석할 수 있었다. 활성화에너지는 0.28~0.33 eV로 시료내 V_(2)O_(5) 의 양이 증가할수록 감소하는 경향을 보인다. 저온 영역에서 직류 전기전도도는 Mott의 가변거리 껑충뛰기(variable-range hopping)전기전도도와 잘 일치하며, N(E_(F))값은 국지화 상태에서와 같다. The dc conductivity of K_(2)O-B_(2)O_(3)-V_(2)O_(5) glasses has been investigated in the temperature range 100~450K and physical parameters such as density, refractive indices, glass transition temperature and fraction of reduced transition-metal ion, were observed for various compositions. The experimental results are analyzed with reference to theoretical models proposed for electrical conduction in amorphous semiconductors. The analysis shows that at high temperature region the temperature dependence of the dc conductivity is consistent with Mott's model of phonon-assisted hopping of small polarons. The values of activation energy are 0.28~0.33 eV and decrease with increasing V_(2)O_(5) content in the sample. The lowtemperature dc conductivity data can be well fitted to Mott's variable-range hopping conductivity and the values of N(E_(F)) are also reasonable for localized states.
김복수,김영훈,강재필,백아영,차유정,김민경,서용문,송승기 명지대학교 자연과학연구소 2004 자연과학논문집 Vol.23 No.-
K_(2)SnCl_(6)는 antifluoride계에 속하는 결정으로서 K_(2)SnCl_(6)에 Li^(+)를 첨가하여 ^(7)Li 핵자기공명(NMR)을 측정하여 동형(isomorphic) 혼합결정(K_(1-x)Rb_(x))_(2)SnCl_(6)와 비동형(nonisomorphic) 혼합결정 K_(2)SnCl_(6):Al^(3+)에서의 핵자기공명(NMR), ^(87)Rb NMR과 ^(27)Al NMR의 측정값과 비교하였다. Rb^(+) 이온은 K_(2)SnCl_(6)의 K^(+)이온을 대신해 동형 결정을 이루며, Al^(3+)이온은 Sn^(4+)이온을 대치하면서 비동형 결정을 이루는데 Li^(+)이온 또한 K^(+)이온을 대신하는 동형 혼합결정과 유사한 결과 값을 얻을 수 있었다. 이 연구 결과는 종래의 Cl-NQR 연구 결과와 비교함으로서 K_(2)SnCl_(6)의 동력학적 특성과 구조 상전이 근처에서의 임계현상을 새로운 관점에서 볼 수 있는 가능성을 보여주었다. ^(7)Li, ^(87)Rb and ^(27)Al NMR have been investigated in the isomorphic and nonisomorphic impurity doped crystals (K_(1-x)Li_(x))_(2)SnCl_(6), (K_(1-x)Rb_(x))_(2)SnCl_(6) and K_(2)SnCl_(6):Al^(3+) as a supplementary to the previous Cl NQR studies in these crystals. The results yielded that the features of NMR spectra for both types of crystals are roughly in line with the systematic trends shown in the Cl NQR in these crystals, though the outstanding characteristics exhibited in the Cl NQR become in the case of the NMR of the doped impurities in crystals somewhat weakend. This is due to the degradation of the role of the local field from the main hamiltonian in NQR to the subsidiary in NMR. Each NMR result of the iso/nonisomorphic crystals has been analyzed in terms of the 'impurity induced dynamic lattice defects' for K_(2)SnCl_(6):Al^(3+) and the 'static primary impurity effects' for (K_(1-x)Rb_(x))_(2)SnCl_(6) and (K_(1-x)Li_(x))_(2)SnCl_(6) respectlvely.
김성수,차영민,민승기 강원대학교 정보통신연구소 2003 정보통신논문지 Vol.7 No.-
There is a continuously growing demand for usable channels that are necessary for communication between mobile users and the base stations of cellular radio networks. However, the number of usable channels is very limited. The objective of this paper is to develop a hybrid method of evolution program(EP) and frequency exhaustive assignment(FEA) for the NP-hard channel-assignment problems to find an optimal channel assignment for minimum interference among the channels within a limited time.
좌각차단을 동반한 심부전증 환자에 실시한 양심실 심박조율기 치료 : 증례 보고
김찬욱,차태준,김성만,김민대,권성일,서수홍,최병주,주승재,이재우 고신대학교 의학부 2002 高神大學校 醫學部 論文集 Vol.17 No.1
Epidemiological studies suggest that 30-50% of patients diagnosed with symptomatic congestive heart failure(CHF) have electrocardiographic evidence of a major intraventricular conduction delay, which may worsen left ventricular systolic and diastolic dysfunction through asynchronous ventricular contraction and paradoxical interventricular septal wall motion. Biventricular pacing is an emerging therapy allowing simultaneous electrical stimulation of the both ventricles with an implantable pacing system and it improves hemodynamics and well-being of patient by reducing ventricular asynchrony. Recently, we underwent biventricular DDD pacemaker implantation in a patient with CHF and Left bundle branch block and was significantly improved exercise tolerance and quality of life in that patient.
김보배,노은경,박서영,박영,오승희,전영란,차현진,윤희상,김수지,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38
This study surveyed and analyzed comparatively college students-knowledge' attitude, was to cultivate the right knowledge and attitude on sex, and serve the foundational data for the suitable sex education. The purpose of the study was to identify and examine: 1) students; sexual knowledge and sexual attitude; 2) the differences between variables of gender, age, and self-perceived sexual knowledge in relation to sexual knowledge and sexual attitude; and 3) the relationship between sexual knowledge and sexual attitude. For this study the questionaires were given to 300 students from five different universities located seoul areas. the questionaires were collected Jenuary 8th to 15th in 2004. Two hundred and nigty one samples were analyzed for the study. The adapted SKAT(saxual knowledge & attitude test; Lief & Reed, 1986) was used to determine sexual knowledge and the students' sexual attitude. Collected data were analyzed statistically by means of percentage, t-test, ANOVA test, and pearson correlation analysis with SPSS 12.0 package program. The main results of this analysis are as follows: Participants consisted of male(48.1%) and female(51.9%) which were mainly between the ages of 21.25(71.8%) with an age range of 19 to 30. Knowledge of sexual disease was scored highest of 92.4%, and konwledge of the knowledge of the male and female's anatomy was the lowest at 60.9%. The respondents' level of sexual attitude was tolerant as on average 3.66(on the basis of 5) Relating to the items, the respondents' score of the sexual curiosity was 4.16, sexual behavior 3.85, self-consolation 3.81, aborthon 3.23, virgine 3.19, extramarital experiences 3.17. There were no significant differences in sexual knowledge between male and females, between younger and older students, residence, sexual experience, and how students mainly obtained their sexual knowledge. But a significant difference was also found religion in their sexual attitude(p<.005). In addition, results showed the relationship between sexual knowledge and sexual attitude(P=0.332).
( Seung Soo Yoo ),( Jae Yong Park ),( Jang Hyuck Lee ),( Mi Jung Hong ),( Jin Eun Choi ),( Sun Ha Choi ),( Yong Hoon Lee ),( Hyewon Seo ),( Jaehee Lee ),( Shin Yup Lee ),( Seung Ick Cha ),( Chang Ho K 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-
Background This study was conducted to investigate the impact of genetic variants in immune checkpoint genes on the treatment outcome of patients with small cell lung cancer (SCLC). Methods Two hundred sixty-one patients who treated with platinum doublet were enrolled. Ninety-six polymorphisms in 33 immune checkpoint related genes were selected and their association with chemotherapy response and overall survival were analyzed. Results Among polymorphisms studied, CD155 rs1058402G>A and CD226 rs763361C>T were significantly associated with the treatment outcome of SCLC. The rs1058402G>A had worse chemotherapy response and worse overall survival (under a dominant model, odds ratio [OR] = 0.52, 95% confidence interval [CI] = 0.27 - 0.99, P = 0.05; hazard ratio [HR] = 1.55, 95% CI = 1.12 - 2.14, P = 0.01, respectively). The rs763361C>T had better chemotherapy response and better overall survival (under a dominant model, OR = 2.03, 95% CI = 1.10 - 3.75, P = 0.02; HR = 0.69, 95% CI = 0.51 - 0.94, P = 0.02, respectively). When the rs1058402GA/AA and rs763361CC genotype were combined, the chemotherapy response and overall survival were significantly decreased as the number of bad genotypes increased (OR = 0.52, 95% CI = 0.33 - 0.81, Ptrend = 0.004; HR = 1.48, 95% CI = 1.19 - 1.84, Ptrend = 4 × 10-4, respectively). CD155 rs1058402G>A and CD226 rs763361C>T are both non-synonymous mutations and change the protein sequence CD155 A67T and CD226 G307S, respectively. 3D structural model showed that CD155 A67T created new hydrogen bond and structural change on CD155. These changes resulted in extending the distance and losing the hydrogen bonds between CD155 and CD226, thus would weaken the binding activity of CD155/ CD226. Conclusions CD155 rs1058402G>A (A67T) and CD226 rs763361C>T (G307S) may be useful for predicting the clinical outcome of SCLC after chemotherapy.
The effect of susceptibility variants identified in never-smoking female lung cancer on male smokers
( Seung Soo Yoo ),( Hyo-gyoung Kang ),( Jin Eun Choi ),( Sun Ha Choi ),( Shin Yup Lee ),( Jaehee Lee ),( Seung Ick Cha ),( Chang Ho Kim ),( Eungbae Lee ),( Jae Yong Park ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Genome wide and candidate gene association studies have identified polymorphisms associated with the risk of lung cancer in never-smokers. This study was conducted to evaluate the association between 11 polymorphisms identified in female never smokers and the lung cancer risk in male smokers. Two polymorphisms were associated with the risk of lung cancer in male smokers, as in female never smokers. Male smokers carrying the rs4975616 variant allele had a significantly decreased risk of lung cancer (in a codominant model: odds ratio=0.77, 95% confidence interval=0.61-0.96, P=0.02). The rs9387478 polymorphism also reduced lung cancer risk in male smokers (in a codominant model: odds ratio=0.85, 95% confidence interval=0.73-1.00, P=0.05). In a stratified analysis, the association between these polymorphisms and the risk of lung cancer was predominant in lighter smokers and for cases of adenocarcinoma. These results suggest that a subset of polymorphisms known to be associated with the risk of lung cancer in female never smokers is also associated with the risk of lung cancer in male smokers.