The effect of combined Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max(OPB) extracts on bone mineral density in ovariectomized rats.

Kim,Jung-Keun 대한구강생물학회 2007 International Journal of Oral Biology Vol.32 No.4

This study was conducted to investigate the preventingeffects of OPB (Rehmannia glutinosa Libosch and Eleuth-erococcus senticosus Max extracts) and combined OPB/Calcium therapy on bone loss in ovariectomized rats. SixtySprague Dawley rats of 12-week-old were divided into eightgroups: OVX (ovariectomized), OPBL (OPB 50mg/kg),OPBM (OPB100mg/kg), OPBH (OPB 200mg/kg), OPBL/CAL(OPBL+CAL), OPBM/CAL (OPBM+CAL), OPBH/CAL (OPBH+CAL) and CAL (Calcium citrate 88.33mg/kg+1α, 25-dihydroxy-vitamin D3 33.33IU/kg). Bone mineraldensity (BMD), bone mineral content (BMC), bone strengthindices and cortical thickness were analyzed by peripheralquantitative computerized tomography (pQCT). pQCTscanning showed that OVX induced a significant decreasein trabecular bone mineral density and bone mineralcontent in the proximal tibia (-36.4±2.4%, -21.8±12.7%).These decreases were significantly prevented by theadministration of OPBM and OPBM/CAL. Cortical BMDand BMC of tibia were slightly enhanced by OPB and OPB/CAL. However there was no significant difference betweenOVX and OPB, OPB/CAL treated group. Bone strengthindices and cortical thickness were not significantly different.Our results suggest that OPB and combined OPB/Calciumtherapy are effective in preventing the development of boneloss induced by ovariectomy in rats.

Plasma estradiol-17βand estrogen receptor increased during the artificial induce sexual maturation and it influence choriocapillary layer of eye in Japanese eel, Anguilla japonica

Ji-Yeon Hyeon,Sung-Pyo Hur,Jun-Hwan Byun,Eun-Su Kim3,Shin-Kwon Kim,Han-Jun Kim,Se-Jae Kim,Akihiro Takemura 한국수산해양기술학회(구 한국어업기술학회) 2018 한국수산해양기술학회 학술발표대회 Vol.2018 No.11

올레산의 비율에 따른 아데노신의 경피 투과의 영향

남현빈,정세진,구민석,오예진,김용민,이훈희,윤수정,임정균 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

In addition to the development of functional cosmetics, technology to increase percutaneous absorption rate when applied to the skin is an important task. In this experiment, oleic acid was used as a skin absorption promoter, and its effect on transdermal permeability of adenosine was studied and analyzed using a skin-like membrane. As a result of the experiment, it was investigated that the permeability coefficient and concentration of adenosine are proportional to the content of oleic acid. This indicates that a high proportion of oleic acid is effective as a skin absorption promoter.

공구흔 동일성 여부 감정기법 개발

김상현,이경화,임세혁,김윤희 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

Resilon을 이용한 근관충전 시 수종의 치면처리제에 따른 미세누출 평가

오종현,박세희,신혜진,조경모,김진우 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.2

이 실험의 목적은 Resilon으로 근관충전된 치아에서 자가산부식전처리제에 따른 치근단 미세누출을 평가하고자 함이다. 70개의 단근치를 사응하였고 .04 Taper ProFile을 사용하여 ISO #40까지 근관성형 하였다. 치아는 근관충전 재료와 자가산부식 전처리제에 따라서 15개씩 4개의 실험군과 5개씩 2개의 대조군으로 나누었다. 실험 치아는 치아 장축에 평행하게 잘라내어 염색액의 최대 침투 길이를 측정하였다. 통계분석은 One-way ANOVA test로 분석하였으며 Scheffe test로 사후검정 하였다. 실험결과 자가산부식전처리제를 사용한 2, 3, 4군 사이에서는 통계적으로 유의한 차이를 나타내지 않았다. 그러나 1군과 4군 사이에서는 통계적으로 유의한 차이가 나타났으며 (p < 0.05), 1군에서 가장 적은 치근단 미세누출을 나타냈다. 이 실험 결과에 따르면 Resilon으로 근관충전을 한 치아는 gutta percha와 AH26^(ⓡ)으로 근관충전할 치아와 비교했을 때 더 좋은 치근단 밀폐를 나타내지 않는다는 결론을 얻었으며, Resilon을 사용하여 근관충전을 한 경우에 자가산부식 전처리제의 차이에 따른 치근단 밀폐효과의 차이를 보이지 않는다는 결론을 얻었다. The purpose of this study was to compare the apical microleakage in root canal filled with Resilon by several self-etching primers and methacrylate-based root canal sealer. Seventy single-rooted human teeth were used in this study. The canals were instrumented by a crown-down manner with Gate-Glidden drills and .04 Taper Profile to ISO #40. The teeth were randomly divided into four experimental groups of 15 teeth each according to root canal filling material and self-etching primers and two control groups (positive and negative) of 5 teeth each as follows: group 1 - gutta percha and AH26^(ⓡ) sealer; group 2 - Resilon, RealSeal™ primer and RealSeal™ sealer; group 3 - Resilon, Clearfil SE Bond^(ⓡ) primer and RealSeal™ sealer group 4 - Resilon, AdheSe^(ⓡ) primer and RealSeal™ sealer. Apical leakage was measured by a maximum length of linear dye penetration of roots sectioned longitudinally by diamond disk. Statistical analysis was performed using the One-way ANOVA followed by Scheffe' s test. There were no statistical differences in the mean apical dye penetration among the groups 2, 3 and 4 of self-etching primers. And group 1, 2 and 3 had also no statistical difference in apical dye penetration. But, there was statistical difference between group 1 and 4 (p < 0.05). The group 1 showed the least dye penetration. According to the results of this study, Resilon with self-etching primer was not sealed root canal better than gutta precha with AH26^(ⓡ) at sealing root canals. And there was no significant difference in apical leakage among the three self-etching primers.

개념적 은유를 활용한 영어 구동사 학습효과

정세현,김현옥 이화여자대학교 교과교육연구소 2011 교과교육학연구 Vol.15 No.4

오랫동안 제2외국어 학습자에게 구동사는 암기의 대상으로 간주되어 왔으나, 인지의미론의 대두와 함께 불변사의 이미지와 영상도식을 활용한 교수방법론의 도입으로 깊이 있는 정보처리에 바탕을 둔 학습의 수월성을 기대할 수 있게 되었다. 본 연구는 고등학교 영어 구동사의 수업에 있어 개념적 은유를 활용한 인지전략의 훈련효과를 고찰하고자. 서울시내에 위치한 고등학교 2학년 101명을 연구대상으로 선정하여 다른 형태의 수업을 실시하고, 사후검사와 후속 장기기억 검사를 시행하였다. 학생들을 세 개의 반으로 분리하여, 통제집단은 기존의 암기전략에 따른 구동사 학습이 진행된 반면, 실험집단 1과 실험집단 2는 영상도식에 근거한 개념적 은유전략을 훈련하였고, 실험집단 2는 은유전략 외에도 해당 구동사와 의미가 같은 단어를 추가적으로 제시하였다. 사후검사 결과, 개념적 은유와 언어자료를 함께 사용한 실험집단 2의 학생들의 학습효과가 가장 높게 나타났고, 다음이 단순암기를 훈련한 통제집단 그리고 개념적 은유만을 활용한 실험집단 1의 순으로 나타났다. 반면, 후속검증에서는 개념적 은유만을 활용한 실험집단 1의 학습효과가 가장 높게, 다음이 통제집단 그리고 개념적 은유와 언어자료가 함께 제시된 실험집단 2의 순으로 나타났다. 이 결과는 제2외국어로서 영어 구동사의 학습에 있어서 가장 많이 활용되어온 암기전략의 수월성으로 인해 전략훈련이 크게 효과적이지 못한 것으로 보인다. 한편, 본 연구의 결과는 개념적 은유에 기초한 인지전략의 훈련을 통한 장기기억의 효과를 기대할 수 있음을 시사하였다. By enhancing an awareness of conceptual metaphors embedded in particles in the construction of phrasal verbs, this study investigated the training effect of conceptual metaphors in learning English phrasal verbs. A total of 101 second-year, high school students were assigned to three different kinds of treatment groups in learning English phrasal verbs. The students in the control group received the conventional type of instruction in learning phrasal verbs using memorization strategies, while the students in the two experimental groups were given awareness tasks by enhancing conceptual metaphors. The second experimental group was also presented with additional linguistic support by providing a word, the meaning of which was identical with that of each phrasal verb. The results showed that the students who received both conceptual metaphors and linguistic input outperformed the students in the control group, indicating that conceptual metaphors help students process the meaning of phrasal verbs. On the other hand, the students in the control group had higher scores than those who only had the image enhancement work; this needs corroborative support through further study. In the test for delayed effect, the students in the metaphor group outperformed those in the control and the second experimental group. When the effect of the instruction was compared with literal versus figurative phrasal verbs, the presentation and explanation of the metaphoric image was seen to be equally facilitative. The findings imply that grammar teaching needs to incorporate alternative approaches including conceptual metaphors and other cognitive strategies.

비기질적인 흉통환자의 정신과적 임상 특성에 대한 연구

서세령,김진세,이현수,정인과 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.5

이 연구는 93년 9월에 5월까지 비기질적인 흉통 환자들중 정신과 진료를 거부한 22명, 정신과 진료를 받은25명과 대조 집단인 공황장애 환자 23명을 대상으로 하였다. 이들에게 불안 및 공포 상태를 평가하기 위해 Sheehan 임상 불안 척도, Spielberg 상태 - 특성 불안 검사, Sheehan 공포 척도와 우울정도를 평가하기위하여 Beck 우울 척도, 생활상의 장애를 평가하기 위해 사회 장애 척도 및 스트레스를 평가하기 위해 사회 재적응 평가 척도를 실시하였으며 다음과 같은 결과를 얻었다. 1) Sheehan 임상 불안 척도, Spielberg 특성 상태 불안 척도, Sheehan 공포 척도, Beck 우울 척도 및 사회 장애 척도에서 3군사이에 통계적으로 의미있는 차이는 없었다. 2) 사회 재적응 평가 척도에서 내과 환자가 공황장애 환자에 비해 통계적으로 유의하게 점수가 높았다. 이와 같은 결과로 비기질적인 흉통 환자들이 정신과적 장애가 있음을 강력히 시사하고 특히 최근 스트레스를 겪은 내과 환자에서 더욱 신속한 정신과적 평가와 치료가 중요하다는 것을 생각할 수 있다. 또한 이런 정신병리는 다시 기질적인 심장질환 발생의 원인이 되기도 하는 바 기기질적인 흉통 환자에 있어서 적극적인 정신과적 치료가 필요하다. Objective : We tried to compare and assess nonorganic chest pain patients and panic disorder patients in clinical manifestations. Methods : We compared the result of clinical scale for anxiety, depression, phobia and avoidance, stress, and social disability in twenty-two patients diagnosed to have nonorganic chest pain and having refused psychiatric consultation, twenty-five patients with nonorganic chest pain admitted to psychiatric department, and twenty-three panic disorder patients with no chest pain. Results : No significant difference was found among the three groups except social readjustment rating scale. Conclusion : The patients with nonorganic chest pain showed as much anxiety, depression, phobia and avoidance, stress, and social disability as the panic patients. Early psychiatric assessment and treatment of patients with nonorganic chest pain is warranted.

공구흔 동일성 감정기법의 실제 감정대상에 적용

임세혁,김상현,이경화,김윤회 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

외안각 절제술과 경결막 절개에 의한 안와 접근법

정종철,김성범,서지훈,송민석,전창훈,최세훈,김현민 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.4

Various surgical approaches to the orbits have been used. But the transconjunctival approach, also called the inferior fornix incision, provides adequate access to the orbital floor with esthetic results. Additionally, transconjunctival approach with lateral canthotomy allows more wide surgical field and good access to the orbital area. Generally, preseptal approach is more used rather than postseptal approach in the transconjunctival incision for the prevention of fat herniation during surgery. There are some complications in transconjunctival approaches but these complications can be prevented with careful surgical techniques. We report clinical results in 12 patients who were treated by preseptal transconjunctival incision with lateral canthotomoy for the treatment of orbital trauma. We were satisfied with this technique for reduction and reconstruction of the orbital trauma and we could also observe relatively good esthetic results.

소목(Caesalpinia sappan) 추출물의 Streptococcus mutans에 대한 성장, 산생성, 부착 및 비수용성 글루칸 합성 억제에 미치는 영향

유용욱,유현희,김윤정,유미선,서세정,이황,이흥수 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.2

Streptococcus mutans is known as the causative bacterial playing the most important role in forming plaque and it is being noticed as major causative bacteria of dental caries. Therefore, development of more effective, substantial and safe preventive agent against dental caries and periodontal disease is honestly required. The present study was designed to investigate the effect of chloroform extract(CE), n-butanol extract(BE),methanol extract(ME) and water extract(WE) of Caesalpinia on the growth, acid production, adhesion, and insoluble glucan synthesis of Streptococcus mutans. The CE, BE, ME and WE decreased the growth and acid production of S.mutans than that of control, especially, the ME was more effective than other extracts. The effect of CE, BE, ME and WE on the adherences to saliva-coated hydroxyapatite bead(S-HA) were evaluated. At the concentration of 2,000 ㎍/㎖, the CE showed 32% rate of bacterial adherence to S-HA, whereas, other extracts of the same concentration producedgreater than 50% rate. The CE and BE were significantly decreased the reduction rates of water insoluble glucan formation from sucrose by crude glucosyltransferase of S.mutans. Thus, the application of C. sappan can be considered a useful and a practical method for the prevention of dental caries.